-
1
-
-
52949108830
-
Anticancer alkylphospholipids: Mechanisms of action, cellular sensitivity and resistance, and clinical prospects
-
van Blitterswijk WJ and Verheij M: Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects. Curr Pharm Des 14: 2061-2074, 2008.
-
(2008)
Curr Pharm des
, vol.14
, pp. 2061-2074
-
-
Van Blitterswijk, W.J.1
Verheij, M.2
-
2
-
-
0032189615
-
Cytotoxic etherphospholipid analogues
-
Berkovic D: Cytotoxic etherphospholipid analogues. Gen Pharmacol 31: 511-517, 1998.
-
(1998)
Gen Pharmacol
, vol.31
, pp. 511-517
-
-
Berkovic, D.1
-
3
-
-
77950641684
-
In vitro and in vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts
-
Mollinedo F, de la Iglesia-Vicente J, Gajate C et al: In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts. Clin Cancer Res 16: 2046-2054, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2046-2054
-
-
Mollinedo, F.1
De La Iglesia-Vicente, J.2
Gajate, C.3
-
4
-
-
1842290345
-
3 (edelfosine): Molecular structure requirements, cellular uptake, and protection by bcl-2 and bcl-x(L)
-
Mollinedo F, Fernández-Luna JL, Gajate C, Martín- Martín B, Benito A, Martínez-Dalmau R and Modolell M: Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L). Cancer Res 57: 1320-1328, 1997. (Pubitemid 27152558)
-
(1997)
Cancer Research
, vol.57
, Issue.7
, pp. 1320-1328
-
-
Mollinedo, F.1
Fernandez-Luna, J.L.2
Gajate, C.3
Martin-Martin, B.4
Benito, A.5
Martinez-Dalmau, R.6
Modolell, M.7
-
5
-
-
25444468325
-
Phospholipids reduce gastric cancer cell adhesion to extracellular matrix in vitro
-
Jansen M, Treutner KH, Schmitz B, Otto J, Jansen P, Neuss S and Schumpelick V: Phospholipids reduce gastric cancer cell adhesion to extracellular matrix in vitro. BMC Gastroenterol 4: 33, 2004.
-
(2004)
BMC Gastroenterol
, vol.4
, pp. 33
-
-
Jansen, M.1
Treutner, K.H.2
Schmitz, B.3
Otto, J.4
Jansen, P.5
Neuss, S.6
Schumpelick, V.7
-
6
-
-
33645767205
-
The inhibition of tumor cell adhesion on human mesothelial cells (HOMC) by phospholipids in vitro
-
Jansen M, Jansen PL, Otto J, Kirtil T, Neuss S, Treutner KH and Schumpelick V: The inhibition of tumor cell adhesion on human mesothelial cells (HOMC) by phospholipids in vitro. Langenbecks Arch Surg 391: 96-101, 2006.
-
(2006)
Langenbecks Arch Surg
, vol.391
, pp. 96-101
-
-
Jansen, M.1
Jansen, P.L.2
Otto, J.3
Kirtil, T.4
Neuss, S.5
Treutner, K.H.6
Schumpelick, V.7
-
7
-
-
77951761725
-
Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids
-
Jiménez-López JM, Ríos-Marco P, Marco C, Segovia JL and Carrasco MP: Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids. Lipids Health Dis 9: 33, 2010.
-
(2010)
Lipids Health Dis
, vol.9
, pp. 33
-
-
Jiménez-López, J.M.1
Ríos-Marco, P.2
Marco, C.3
Segovia, J.L.4
Carrasco, M.P.5
-
8
-
-
64549139703
-
Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells
-
Gajate C, Gonzalez-Camacho F and Mollinedo F: Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells. PLoS One 4: 5044, 2009.
-
(2009)
PLoS One
, vol.4
, pp. 5044
-
-
Gajate, C.1
Gonzalez-Camacho, F.2
Mollinedo, F.3
-
9
-
-
72449158057
-
The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma
-
Kumar A, Fillmore HL, Kadian R, Broaddus WC, Tye GW and Van Meter TE: The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma. Mol Cancer Res 7: 1813-1821, 2009.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1813-1821
-
-
Kumar, A.1
Fillmore, H.L.2
Kadian, R.3
Broaddus, W.C.4
Tye, G.W.5
Van Meter, T.E.6
-
10
-
-
45049086503
-
Perifosine induces differentiation and cell death in prostate cancer cells
-
Floryk D and Thompson TC: Perifosine induces differentiation and cell death in prostate cancer cells. Cancer Letter 266: 216-226, 2008.
-
(2008)
Cancer Letter
, vol.266
, pp. 216-226
-
-
Floryk, D.1
Thompson, T.C.2
-
11
-
-
78651521276
-
Perifosine induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cell lines by blockade of Akt phosphorylation
-
Fei HR, Chen G, Wang JM and Wang FZ: Perifosine induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cell lines by blockade of Akt phosphorylation. Cytotechnology 62: 449-460, 2010.
-
(2010)
Cytotechnology
, vol.62
, pp. 449-460
-
-
Fei, H.R.1
Chen, G.2
Wang, J.M.3
Wang, F.Z.4
-
12
-
-
0036305933
-
Structure-activity relationships of alkylphosphocholine derivatives: Antineoplastic action on brain tumor cell lines in vitro
-
DOI 10.1007/s00280-002-0440-8
-
Jendrossek V, Hammersen K, Erdlenbruch B, Kugler W, Krügener R, Eibl H and Lakomek M: Structure-activity relationships of alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro. Cancer Chemother Pharmacol 50: 71-79, 2002. (Pubitemid 34743999)
-
(2002)
Cancer Chemotherapy and Pharmacology
, vol.50
, Issue.1
, pp. 71-79
-
-
Jendrossek, V.1
Hammersen, K.2
Erdlenbruch, B.3
Kugler, W.4
Krugener, R.5
Eibl, H.6
Lakomek, M.7
-
13
-
-
79952917187
-
Synthetic Phosphoethanolamine Induces Apoptosis Through Caspase-3 Pathway by Decreasing Expression of Bax/Bad Protein and Changes Cell Cycle in Melanoma
-
Ferreira AK, Meneguelo R, Neto SC, Chierice GO and Maria DA: Synthetic Phosphoethanolamine Induces Apoptosis Through Caspase-3 Pathway by Decreasing Expression of Bax/Bad Protein and Changes Cell Cycle in Melanoma. J Cancer Sci Ther 3: 053-059, 2011.
-
(2011)
J Cancer Sci Ther
, vol.3
, pp. 053-059
-
-
Ferreira, A.K.1
Meneguelo, R.2
Neto, S.C.3
Chierice, G.O.4
Maria, D.A.5
-
14
-
-
0026663526
-
Tumor cell kinetics following antineoplastic ether phospholipid treatment
-
Principe P, Sidoti C and Braquet P: Tumor cell kinetics following antineoplastic ether phospholipid treatment. Cancer Res 52: 2509-2515, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2509-2515
-
-
Principe, P.1
Sidoti, C.2
Braquet, P.3
-
15
-
-
0028083999
-
Tumor cell kinetics following long-term treatment with antineoplastic ether phospholipids
-
Principe P, Sidoti C, Coulomb H, Broquet C and Braquet P: Tumor cell kinetics following long-term treatment with antineoplastic ether phospholipids. Cancer Detect Prev 18: 393-400, 1994. (Pubitemid 2156069)
-
(1994)
Cancer Detection and Prevention
, vol.18
, Issue.5
, pp. 393-400
-
-
Principe, P.1
Sidoti, C.2
Coulomb, H.3
Broquet, C.4
Braquet, P.5
-
16
-
-
33847289770
-
Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy
-
DOI 10.1016/j.ctrv.2006.12.001, PII S0305737206002386
-
Vink SR, van Blitterswijk WJ, Schellens JH and Verheij M: Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy. Cancer Treat Rev 33: 191-202, 2007. (Pubitemid 46323398)
-
(2007)
Cancer Treatment Reviews
, vol.33
, Issue.2
, pp. 191-202
-
-
Vink, S.R.1
Van Blitterswijk, W.J.2
Schellens, J.H.M.3
Verheij, M.4
-
17
-
-
77951675862
-
Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membranetargeted alkylphospholipid analogues
-
Carrasco MP, Jiménez-López JM, Ríos-Marco P, Segovia JL and Marco C: Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membranetargeted alkylphospholipid analogues. Br J Pharmacol 160: 355-366, 2010.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 355-366
-
-
Carrasco, M.P.1
Jiménez-López, J.M.2
Ríos-Marco, P.3
Segovia, J.L.4
Marco, C.5
-
18
-
-
77950920621
-
Glycosidated phospholipids: Uncoupling of signalling pathways at the plasma membrane
-
Danker K, Reutter W and Semini G: Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane. Br J Pharmacol 160: 36-47, 2010.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 36-47
-
-
Danker, K.1
Reutter, W.2
Semini, G.3
-
19
-
-
0030763045
-
3 and the DNA-interacting agent, etoposide
-
Fujiwara K, Koike H, Ohishi Y, Shirafuji H, Kohno I, Modest EJ and Kataoka S: Cytokinetic and morphologic differences in ovarian cancer cells treated with ET-18-OCH3 and the DNA-interacting agent, etoposide. Anticancer Res 17: 2159-67, 1997. (Pubitemid 27320962)
-
(1997)
Anticancer Research
, vol.17
, Issue.3 C
, pp. 2159-2167
-
-
Fujiwara, K.1
Koike, H.2
Ohishi, Y.3
Shirafuji, H.4
Kohno, I.5
Modest, E.J.6
Kataoka, S.7
-
20
-
-
0026648486
-
Anti-neoplastic action of peritoneal macrophages following oral administration of ether analogues of lysophospholipids
-
Ngwenya BZ, Fiavey NP and Mogashoa MM: Anti-neoplastic action of peritoneal macrophages following oral administration of ether analogues of lysophospholipids. Eur J Cancer 28: 1637-1642, 1992.
-
(1992)
Eur J Cancer
, vol.28
, pp. 1637-1642
-
-
Ngwenya, B.Z.1
Fiavey, N.P.2
Mogashoa, M.M.3
-
21
-
-
43749088540
-
Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: Single activity and combination with other antileukemic drugs
-
DOI 10.1007/s00280-007-0612-7
-
Fiegl M, Lindner LH, Juergens M, Eibl H, Hiddemann W and Braess J: Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: single activity and combination with other antileukemic drugs. Cancer Chemother Pharmacol 62: 321-329, 2008. (Pubitemid 351692092)
-
(2008)
Cancer Chemotherapy and Pharmacology
, vol.62
, Issue.2
, pp. 321-329
-
-
Fiegl, M.1
Lindner, L.H.2
Juergens, M.3
Eibl, H.4
Hiddemann, W.5
Braess, J.6
-
22
-
-
0034520113
-
Permeabilization of the mitochondrial inner membrane during apoptosis: Impact of the adenine nucleotide translocator
-
DOI 10.1038/sj.cdd.4400778
-
Vieira HL, Haouzi D, El Hamel C, Jacotot E, Belzacq AS, Brenner C and Kroemer G: Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator. Cell Death Differ 7: 1146-1154, 2000. (Pubitemid 32042221)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.12
, pp. 1146-1154
-
-
Vieira, H.L.A.1
Haouzi, D.2
El, H.C.3
Jacotot, E.4
Belzacq, A.-S.5
Brenner, C.6
Kroemer, G.7
-
23
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
Riedl SJ and Salvesen GS: The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 8: 405-401, 2007.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 405-1401
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
25
-
-
67650751080
-
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
-
Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C et al: Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 16: 1093-1107, 2009.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1093-1107
-
-
Galluzzi, L.1
Aaronson, S.A.2
Abrams, J.3
Alnemri, E.S.4
Andrews, D.W.5
Baehrecke, E.H.6
Bazan, N.G.7
Blagosklonny, M.V.8
Blomgren, K.9
Borner, C.10
Bredesen, D.E.11
Brenner, C.12
-
26
-
-
77956095537
-
Mitochondria and cell death: Outer membrane permeabilization and beyond
-
Tait SW and Green DR: Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 11: 621-632, 2010.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
27
-
-
60549104289
-
Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins
-
Aouacheria A, Cibiel A, Guillemin Y, Gillet G and Lalle P: Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins. Recent Pat DNA Gene Seq 1: 43-46, 2007.
-
(2007)
Recent Pat DNA Gene Seq
, vol.1
, pp. 43-46
-
-
Aouacheria, A.1
Cibiel, A.2
Guillemin, Y.3
Gillet, G.4
Lalle, P.5
-
28
-
-
0038052805
-
The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
-
DOI 10.1046/j.1365-2184.2003.00266.x
-
Vermeulen K, Van Bockstaele DR and Berneman ZN: The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 36: 131-149, 2003. (Pubitemid 36808270)
-
(2003)
Cell Proliferation
, vol.36
, Issue.3
, pp. 131-149
-
-
Vermeulen, K.1
Van Bockstaele, D.R.2
Berneman, Z.N.3
-
29
-
-
80054727886
-
Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: Involvement of intrinsic pathway
-
Aghaei M, Panjehpour M, Karami-Tehrani F and Salami S: Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway. J Cancer Res Clin Oncol 2011.
-
(2011)
J Cancer Res Clin Oncol
-
-
Aghaei, M.1
Panjehpour, M.2
Karami-Tehrani, F.3
Salami, S.4
|