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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 1027-1030

Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors

(3) Park, Hwangseo a Jeong, Yujeong b Hong, Sungwoo b

a Sejong University (South Korea)

b Korea Advanced Institute of Science and Technology (KAIST) (South Korea)

Author keywords

Anticancer agents; BRAF kinase; De novo design; Docking; Inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATE; B RAF KINASE INHIBITOR;

ARTICLE; BINDING SITE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; ENZYME INHIBITION; PHYSICAL CHEMISTRY;

AMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS B-RAF; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE;

EID: 84855708686 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.124 Document Type: Article

Times cited : (14)

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