Gating NO release from nitric oxide synthase

Journal of the American Chemical Society

Volumn 134, Issue 1, 2012, Pages 27-30

  Whited, Charlotte A ^a   Warren, Jeffrey J ^a   Lavoie, Katherine D ^a   Weinert, Emily E ^b   Agapie, Theodor ^a   Winkler, Jay R ^a   Gray, Harry B ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER SOLUTIONS; DIATOMIC MOLECULES; DOUBLE MUTANTS; GEOBACILLUS STEAROTHERMOPHILUS; KINETICS EXPERIMENTS; MAMMALIAN ENZYMES; NITRIC-OXIDE SYNTHASE; NO RELEASE; SINGLE MUTANT; STOPPED FLOW; WILD-TYPE ENZYMES;

AMINO ACIDS; KINETICS; MAMMALS; NITRIC OXIDE;

ENZYMES;

ARGININE; BUFFER; N HYDROXYARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ABSORPTION; ARTICLE; ENZYME ACTIVE SITE; GEOBACILLUS STEAROTHERMOPHILUS; MUTANT; NONHUMAN; PH; ULTRAVIOLET RADIATION;

CATALYTIC DOMAIN; GEOBACILLUS STEAROTHERMOPHILUS; KINETICS; MODELS, MOLECULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 84855684273     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2069533     Document Type: Article

References (30)

1. Marletta, M. A. J. Biol. Chem. 1993, 268, 12231
2. Wei, C. C.; Wang, Z. Q.; Stuehr, D. J. In Enzyme Kinetics and Mechanism, Part F: Detection and Characterization of Enzyme Reaction Intermediates; Academic Press Inc: San Diego, 2002; Vol. 354, p 320.
3. Marletta, M. A.; Hurshman, A. R.; Rusche, K. M. Curr. Opin. Chem. Biol. 1998, 2, 656
4. Alderton, W. K.; Cooper, C. E.; Knowles, R. G. Biochem. J. 2001, 357, 593
5. Gusarov, I.; Shatalin, K.; Starodubtseva, M.; Nudler, E. Science 2009, 325, 1380
6. Gusarov, I.; Starodubtseva, M.; Wang, Z. Q.; McQuade, L.; Lippard, S. J.; Stuehr, D. J.; Nudler, E. J. Biol. Chem. 2008, 283, 13140
7. Johnson, E. G.; Sparks, J. P.; Dzikovski, B.; Crane, B. R.; Gibson, D. M.; Loria, R. Chem. Biol. 2008, 15, 43
8. Dawson, J. H.; Sono, M. Chem. Rev. 1987, 87, 1255
9. Gorren, A. C. F.; Mayer, B. Biochim. Biophys. Acta 2007, 1770, 432
10. Sono, M.; Roach, M. P.; Coulter, E. D.; Dawson, J. H. Chem. Rev. 1996, 96, 2841
11. Stuehr, D.; Pou, S.; Rosen, G. M. J. Biol. Chem. 2001, 276, 14533
12. Stuehr, D. J.; Santolini, J.; Wang, Z. Q.; Wei, C. C.; Adak, S. J. Biol. Chem. 2004, 279, 36167
13. Stuehr, D. J.; Tejero, J.; Haque, M. M. FEBS J. 2009, 276, 3959
14. Sudhamsu, J.; Crane, B. R. Trends Microbiol. 2009, 17, 212
15. Beaumont, E.; Lambry, J. C.; Wang, Z. Q.; Stuehr, D. J.; Martin, J. L.; Slama-Schwok, A. Biochemistry 2007, 46, 13533
16. Salard, I.; Mercey, E.; Rekka, E.; Boucher, J. L.; Nioche, P.; Mikula, I.; Martasek, P.; Raman, C. S.; Mansuy, D. J. Inorg. Biochem. 2006, 100, 2024
17. Wang, Z. Q.; Wei, C. C.; Sharma, M.; Pant, K.; Crane, B. R.; Stuehr, D. J. J. Biol. Chem. 2004, 279, 19018
18. Wang, Z. Q.; Wei, C. C.; Stuehr, D. J. J. Inorg. Biochem. 2010, 104, 349
19. Crane, B. R.; Sudhamsu, J.; Patel, B. A. Annu. Rev. Biochem. 2010, 79, 445
20. Sudhamsu, J.; Crane, B. R. J. Biol. Chem. 2006, 281, 9623
21. Reece, S. Y.; Woodward, J. J.; Marletta, M. A. Biochemistry 2009, 48, 5483
22. Agapie, T.; Suseno, S.; Woodward, J. J.; Stoll, S.; Britt, R. D.; Marletta, M. A. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 16221
23. Zhou, L.; Zhu, D. Y. Nitric Oxide-Biol. Chem. 2009, 20, 223
24. Boggs, S.; Huang, L. X.; Stuehr, D. J. Biochemistry 2000, 39, 2332
25. Tejero, J. S.; Biswas, A.; Wang, Z. Q.; Page, R. C.; Haque, M. M.; Hemann, C.; Zweier, J. L.; Misra, S.; Stuehr, D. J. J. Biol. Chem. 2008, 283, 33498
26. Binstead, R. A.; Zuberbühler, A. D.; Jung, B. Specfit, version 3.0.38 (32-bit Windows); Spectrum Software Associates: Chapel Hill, NC, 2006.
27. Tejero, J. S.; Biswas, A.; Wang, Z. Q.; Page, R. C.; Haque, M. M.; Hemann, C.; Zweier, J. L.; Misra, S.; Stuehr, D. J. J. Biol. Chem. 2008, 283, 33498
28. Reversible oxidation of NOHA is very unlikely based on the currently proposed mechanism(s). See: Woodward, J. J.; Chang, M. M.; Martin, N. I.; Marletta., M. A. J. Am. Chem. Soc. 2008, 131, 297-305
29. Wei, C. C.; Wang, Z. Q.; Tejero, J.; Yang, Y. P.; Hemann, C.; Hille, R.; Stuehr, D. J. J. Biol. Chem. 2008, 283, 11734
30. Woodward, J. J.; NejatyJahromy, Y.; Britt, R. D.; Marletta, M. A. J. Am. Chem. Soc. 2010, 132, 5105