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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 1068-1072

Facile synthesis of tetracyclic azepine and oxazocine derivatives and their potential as MAPKAP-K2 (MK2) inhibitors

(10) Rao, Ashwin U a Xiao, Dong a Huang, Xianhai a Zhou, Wei a Fossetta, James a Lundell, Dan a Tian, Fang a Trivedi, Prashant a Aslanian, Robert a Palani, Anandan a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Azepine; MK2; Oxazocine; Tetracyclic

Indexed keywords

AZEPINE DERIVATIVE; OXAZOCINE DERIVATIVE; SYNAPTOPHYSIN; SYNAPTOPHYSIN MK2; TETRACYCLIC AZEPINE DERIVATIVE; TETRACYCLIC OXAZOCINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; DRUG STRUCTURE; DRUG SYNTHESIS;

AZEPINES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR STRUCTURE; OXAZOCINES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855680778 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.113 Document Type: Article

Times cited : (51)

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