-
2
-
-
0036284984
-
The role of TH1/TH2 polarization in mucosal immunity
-
DOI 10.1038/nm0602-567
-
Neurath MF, Finotto S, Glimcher LH,. The role of Th1/Th2 polarization in mucosal immunity. Nat Med. 2002; 8: 567-573. (Pubitemid 34633433)
-
(2002)
Nature Medicine
, vol.8
, Issue.6
, pp. 567-573
-
-
Neurath, M.F.1
Finotto, S.2
Glimcher, L.H.3
-
3
-
-
0037043658
-
Inflammatory bowel disease
-
DOI 10.1056/NEJMra020831
-
Podolsky DK,. Inflammatory bowel disease. N Engl J Med. 2002; 347: 417-429. (Pubitemid 34851835)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.6
, pp. 417-429
-
-
Podolsky, D.K.1
-
4
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
DOI 10.1126/science.1135245
-
Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006; 314: 1461-1463. (Pubitemid 44871953)
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
5
-
-
34249030920
-
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
-
DOI 10.1002/ibd.20126
-
Dubinsky MC, Wang D, Picornell Y, et al. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm Bowel Dis. 2007; 13: 511-515. (Pubitemid 46799633)
-
(2007)
Inflammatory Bowel Diseases
, vol.13
, Issue.5
, pp. 511-515
-
-
Dubinsky, M.C.1
Wang, D.2
Picornell, Y.3
Wrobel, I.4
Katzir, L.5
Quiros, A.6
Dutridge, D.7
Wahbeh, G.8
Silber, G.9
Bahar, R.10
Mengesha, E.11
Targan, S.R.12
Taylor, K.D.13
Rotter, J.I.14
-
6
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, et al. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology. 2008; 135: 1130-1141.
-
(2008)
Gastroenterology.
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
-
7
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
DOI 10.1084/jem.20070663
-
Annunziato F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17. J Exp Med. 2007; 204: 1849-1861. (Pubitemid 47240944)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.8
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Fili, L.8
Ferri, S.9
Frosali, F.10
Giudici, F.11
Romagnani, P.12
Parronchi, P.13
Tonelli, F.14
Maggi, E.15
Romagnani, S.16
-
9
-
-
72549107316
-
Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
-
Rovedatti L, Kudo T, Biancheri P, et al. Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease. Gut. 2009; 58: 1629-1636.
-
(2009)
Gut.
, vol.58
, pp. 1629-1636
-
-
Rovedatti, L.1
Kudo, T.2
Biancheri, P.3
-
10
-
-
53049091561
-
A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, et al. A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology. 2008; 135: 1130-1141.
-
(2008)
Gastroenterology.
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
-
12
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
DOI 10.1126/science.1106442
-
MacDonald TT, Monteleone G,. Immunity, inflammation, and allergy in the gut. Science. 2005; 307: 1920-1925. (Pubitemid 40404695)
-
(2005)
Science
, vol.307
, Issue.5717
, pp. 1920-1925
-
-
MacDonald, T.T.1
Monteleone, G.2
-
13
-
-
78649704149
-
Interleukin-25: A two-edged sword in the control of immune-inflammatory responses
-
Monteleone G, Pallone F, Macdonald TT,. Interleukin-25: a two-edged sword in the control of immune-inflammatory responses. Cytokine Growth Factor Rev. 2010; 21: 471-475.
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 471-475
-
-
Monteleone, G.1
Pallone, F.2
MacDonald, T.T.3
-
14
-
-
66149156478
-
Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut
-
Caruso R, Sarra M, Stolfi C, et al. Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut. Gastroenterology. 2009; 136: 2270-2279.
-
(2009)
Gastroenterology.
, vol.136
, pp. 2270-2279
-
-
Caruso, R.1
Sarra, M.2
Stolfi, C.3
-
15
-
-
18244387204
-
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
-
DOI 10.1038/ni1192
-
Rimoldi M, Chieppa M, Salucci V, et al. Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat Immunol. 2005; 6: 507-514. (Pubitemid 41716764)
-
(2005)
Nature Immunology
, vol.6
, Issue.5
, pp. 507-514
-
-
Rimoldi, M.1
Chieppa, M.2
Salucci, V.3
Avogadri, F.4
Sonzogni, A.5
Sampietro, G.M.6
Nespoli, A.7
Viale, G.8
Allavena, P.9
Rescigno, M.10
-
16
-
-
70349208627
-
Dendritic cells in intestinal homeostasis and disease
-
Rescigno M, Di Sabatino A,. Dendritic cells in intestinal homeostasis and disease. J Clin Invest. 2009; 119: 2441-2450.
-
(2009)
J Clin Invest.
, vol.119
, pp. 2441-2450
-
-
Rescigno, M.1
Di Sabatino, A.2
-
17
-
-
36749038197
-
Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease
-
DOI 10.1136/gut.2006.116467
-
Kugathasan S, Saubermann LJ, Smith L, et al. Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease. Gut. 2007; 56: 1696-1705. (Pubitemid 350206296)
-
(2007)
Gut
, vol.56
, Issue.12
, pp. 1696-1705
-
-
Kugathasan, S.1
Saubermann, L.J.2
Smith, L.3
Kou, D.4
Itoh, J.5
Binion, D.G.6
Levine, A.D.7
Blumberg, R.S.8
Fiocchi, C.9
-
18
-
-
34249799285
-
- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β
-
Xu L, Kitani A, Fuss I, Strober W,. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol. 2007; 178: 6725-6729. (Pubitemid 46847395)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 6725-6729
-
-
Xu, L.1
Kitani, A.2
Fuss, I.3
Strober, W.4
-
19
-
-
67049097104
-
Developmental plasticity of Th17 and Treg cells
-
Lee YK, Mukasa R, Hatton RD, Weaver CT,. Developmental plasticity of Th17 and Treg cells. Curr Opin Immunol. 2009; 21: 274-280.
-
(2009)
Curr Opin Immunol.
, vol.21
, pp. 274-280
-
-
Lee, Y.K.1
Mukasa, R.2
Hatton, R.D.3
Weaver, C.T.4
-
20
-
-
33745536739
-
Functional consequences of NOD2 (CARD15) mutations
-
DOI 10.1097/01.MIB.0000225332.83861.5f, PII 0005472520060700000014
-
Abraham C, Cho JH,. Functional consequences of NOD2 (CARD15) mutations. Inflamm Bowel Dis. 2006; 12: 641-650. (Pubitemid 43977746)
-
(2006)
Inflammatory Bowel Diseases
, vol.12
, Issue.7
, pp. 641-650
-
-
Abraham, C.1
Cho, J.H.2
-
21
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
DOI 10.1086/339432
-
Lesage S, Zouali H, Cézard JP, et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet. 2002; 70: 845-857. (Pubitemid 34259301)
-
(2002)
American Journal of Human Genetics
, vol.70
, Issue.4
, pp. 845-857
-
-
Lesage, S.1
Zouali, H.2
Cezard, J.-P.3
Colombel, J.-F.4
Belaiche, J.5
Almer, S.6
Tysk, C.7
O'Morain, C.8
Gassull, M.9
Binder, V.10
Finkel, Y.11
Modigliani, R.12
Gower-Rousseau, C.13
Macry, J.14
Merlin, F.15
Chamaillard, M.16
Jannot, A.-S.17
Thomas, G.18
Hugot, J.-P.19
-
22
-
-
29144483937
-
Reduced Paneth cell α-defensins in ileal Crohn's disease
-
DOI 10.1073/pnas.0505256102
-
Wehkamp J, Salzman NH, Porter E, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A. 2005; 102: 18129-18134. (Pubitemid 41798513)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.50
, pp. 18129-18134
-
-
Wehkamp, J.1
Salzman, N.H.2
Porter, E.3
Nuding, S.4
Weichenthal, M.5
Petras, R.E.6
Shen, B.7
Schaeffeler, E.8
Schwab, M.9
Linzmeier, R.10
Feathers, R.W.11
Chu, H.12
Lima Jr., H.13
Fellermann, K.14
Ganz, T.15
Stange, E.F.16
Bevins, C.L.17
-
23
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
DOI 10.1038/nri2161, PII NRI2161
-
Levine B, Deretic V,. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol. 2007; 7: 767-777. (Pubitemid 47480305)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
24
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007; 39: 207-211. (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
25
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16L1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16L1 in mouse and human intestinal Paneth cells. Nature. 2008; 456: 259-263.
-
(2008)
Nature.
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
26
-
-
46049083963
-
Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease
-
DOI 10.1053/j.gastro.2008.04.002, PII S0016508508006276
-
Vetrano S, Rescigno M, Cera MR, et al. Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease. Gastroenterology. 2008; 135: 173-184. (Pubitemid 351899025)
-
(2008)
Gastroenterology
, vol.135
, Issue.1
, pp. 173-184
-
-
Vetrano, S.1
Rescigno, M.2
Rosaria Cera, M.3
Correale, C.4
Rumio, C.5
Doni, A.6
Fantini, M.7
Sturm, A.8
Borroni, E.9
Repici, A.10
Locati, M.11
Malesci, A.12
Dejana, E.13
Danese, S.14
-
27
-
-
0242678327
-
Increased Enterocyte Apoptosis in Inflamed Areas of Crohn's Disease
-
DOI 10.1007/s10350-004-6802-z
-
Di Sabatino A, Ciccocioppo R, Luinetti O, et al. Increased enterocyte apoptosis in inflamed areas of Crohn's disease. Dis Colon Rectum. 2003; 46: 1498-1507. (Pubitemid 37429731)
-
(2003)
Diseases of the Colon and Rectum
, vol.46
, Issue.11
, pp. 1498-1507
-
-
Di Sabatino, A.1
Ciccocioppo, R.2
Luinetti, O.3
Ricevuti, L.4
Morera, R.5
Cifone, M.G.6
Solcia, E.7
Corazza, G.R.8
-
28
-
-
0032733508
-
Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease
-
Souza HS, Elia CC, Spencer J, et al. Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease. Gut. 1999; 45: 856-863.
-
(1999)
Gut.
, vol.45
, pp. 856-863
-
-
Souza, H.S.1
Elia, C.C.2
Spencer, J.3
-
29
-
-
0038297520
-
Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients
-
DOI 10.1016/S0016-5085(03)00289-0
-
Danese S, de la Motte C, Sturm A, et al. Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients. Gastroenterology. 2003; 124: 1249-1264. (Pubitemid 36531801)
-
(2003)
Gastroenterology
, vol.124
, Issue.5
, pp. 1249-1264
-
-
Danese, S.1
De La Motte, C.2
Sturm, A.3
Vogel, J.D.4
West, G.A.5
Strong, S.A.6
Katz, J.A.7
Fiocchi, C.8
-
30
-
-
67649888821
-
Intestinal fibrosis in IBD â a dynamic, multifactorial process
-
Rieder F, Fiocchi C,. Intestinal fibrosis in IBD â a dynamic, multifactorial process. Nat Rev. 2009; 6: 228-235.
-
(2009)
Nat Rev.
, vol.6
, pp. 228-235
-
-
Rieder, F.1
Fiocchi, C.2
-
31
-
-
66649106333
-
Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures
-
Di Sabatino A, Jackson CL, Pickard KM, et al. Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures. Gut. 2009; 58: 777-789.
-
(2009)
Gut.
, vol.58
, pp. 777-789
-
-
Di Sabatino, A.1
Jackson, C.L.2
Pickard, K.M.3
|