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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 876-880

Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases

(5) Sabbah, Dima A a Simms, Neka A b Brattain, Michael G b Vennerstrom, Jonathan L a Zhong, Haizhen c

a NEBRASKA MEDICAL CENTER (United States)

b UNIVERSITY OF NEBRASKA MEDICAL CENTER (United States)

c UNIVERSITY OF NEBRASKA AT OMAHA (United States)

Author keywords

Apoptosis; Docking; GSK2126458; LY294002; Pharmacophore modeling; PI3K

Indexed keywords

NSC 408120; NSC 675972; NSC 79888; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; COLON CANCER; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; PHARMACOPHORE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855662356 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.12.044 Document Type: Article

Times cited : (30)

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