-
1
-
-
78650407231
-
Identification of PP2A complexes and pathways involved in cell transformation
-
Sobhna AA, Hector M, Colpaert N, Hahn WC. Identification of PP2A complexes and pathways involved in cell transformation. Cancer Res 2010;70:10474-84.
-
(2010)
Cancer Res
, vol.70
, pp. 10474-10484
-
-
Sobhna, A.A.1
Hector, M.2
Colpaert, N.3
Hahn, W.C.4
-
2
-
-
12344308021
-
PP2A: The expected tumor suppressor
-
DOI 10.1016/j.gde.2004.12.004, PII S0959437X0400190X, Oncogenes and Cell Proliferation
-
Janssens V, Jozef Goris J, Van Hoof C. PP2A: the expected tumor suppressor. Curr Opin Genet Dev 2005;15:34-41. (Pubitemid 40127629)
-
(2005)
Current Opinion in Genetics and Development
, vol.15
, Issue.1
, pp. 34-41
-
-
Janssens, V.1
Goris, J.2
Van Hoof, C.3
-
4
-
-
0033621057
-
Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A
-
DOI 10.1073/pnas.96.18.10080
-
Shtrichman R, Sharf R, Barr H, et al. Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A. Proc. Natl Acad Sci USA 1999;96:10080-5. (Pubitemid 29422515)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.18
, pp. 10080-10085
-
-
Shtrichman, R.1
Sharf, R.2
Barr, H.3
Dobner, T.4
Kleinberger, T.5
-
5
-
-
0019505477
-
Association of cellular 56,000- and 32,000-molecular-weight proteins with BK virus and polyoma virus t-antigens
-
Rundell K, Major EO, Lanpert M. Association of cellular 56000-and 32000-molecular-weight protein with BK virus and polyoma virus t-antigens. J Virol 1981;37:1090-3. (Pubitemid 11102664)
-
(1981)
Journal of Virology
, vol.37
, Issue.3
, pp. 1090-1093
-
-
Rundell, K.1
Major, E.O.2
Lampert, M.3
-
6
-
-
34447270509
-
Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A
-
Garibal J, Hollville E, Bell Al, et al. Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A. J Virol 2007;81:598-607.
-
(2007)
J Virol
, vol.81
, pp. 598-607
-
-
Garibal, J.1
Hollville, E.2
Al, B.3
-
7
-
-
43249107658
-
Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: Inhibition by small t antigen
-
Sariyer IK, Khalili K, Safak M. Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: inhibition by small t antigen. Virology 2008;375:64-79.
-
(2008)
Virology
, vol.375
, pp. 64-79
-
-
Sariyer, I.K.1
Khalili, K.2
Safak, M.3
-
8
-
-
77956500009
-
JC virus small t antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity
-
Bollag B, Hofstetter CA, Reviriego-Mendoza MM, Frisque RJ. JC virus small t antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity PLoS One 2010;5:e10606.
-
(2010)
PLoS One
, vol.5
-
-
Bollag, B.1
Hofstetter, C.A.2
Reviriego-Mendoza, M.M.3
Frisque, R.J.4
-
9
-
-
33746134804
-
The protein phosphatase 2A represents a novel cellular target for hepatitis C virus NS5A protein
-
DOI 10.1016/j.biochi.2005.12.003, PII S0300908405002774
-
Georgopoulou U, Tsitoura P, Kalamvoki M, Mavromara P. The protein phosphatase 2A represents a novel cellular target for hepatitis C virus NS5A protein. Biochimie 2006;88:651-62. (Pubitemid 44081829)
-
(2006)
Biochimie
, vol.88
, Issue.6
, pp. 651-662
-
-
Georgopoulou, U.1
Tsitoura, P.2
Kalamvoki, M.3
Mavromara, P.4
-
10
-
-
78249270751
-
PP2A, binding, cell transducing and apoptotic properties of Vpr7MI: A new functional domain of HIV-1 Vpr proteins
-
Godet AN, Guergnon J, Croset A, et al. PP2A, binding, cell transducing and apoptotic properties of Vpr7MI: a new functional domain of HIV-1 Vpr proteins. PLoS One 2010;5:e13760.
-
(2010)
PLoS One
, vol.5
-
-
Godet, A.N.1
Guergnon, J.2
Croset, A.3
-
11
-
-
28344447599
-
Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A
-
Pirn D, Massimi P, Dilworth SM, Banks L. Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A. Oncogene 2005;24:830-8.
-
(2005)
Oncogene
, vol.24
, pp. 830-838
-
-
Pirn, D.1
Massimi, P.2
Dilworth, S.M.3
Banks, L.4
-
12
-
-
70450170962
-
The minimum replication origin of Merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication
-
Kwun HJ, Guastafierro A, Shuda M, et al. The minimum replication origin of Merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication. J Virol 2009;83:12118-28.
-
(2009)
J Virol
, vol.83
, pp. 12118-12128
-
-
Kwun, H.J.1
Guastafierro, A.2
Shuda, M.3
-
13
-
-
0035950606
-
Polyoma virus: Old findings and new challenges
-
DOI 10.1006/viro.2001.1124
-
Benjamin TL. Polyoma virus: old findings and new challenges. Virology 2001;289:167-73. (Pubitemid 33140995)
-
(2001)
Virology
, vol.289
, Issue.2
, pp. 167-173
-
-
Benjamin, T.L.1
-
14
-
-
0036884703
-
Polyoma virus middle T antigen and its role in identifying cancer-related molecules
-
DOI 10.1038/nrc946
-
Dilworth SM. Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nat Rev Cancer 2002;2:951-6. (Pubitemid 37328896)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.12
, pp. 951-956
-
-
Dilworth, S.M.1
-
15
-
-
34249717337
-
Heptad repeats regulate protein phosphatase 2A recruitment to I-κB kinase γ/NF-κB essential modulator and are targeted by human T-lymphotropic virus type 1 tax
-
DOI 10.1074/jbc.M610392200
-
Hong S, Wang LC, Gao X, et al. Heptad repeats regulate protein phosphatase 2a recruitment to 1-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax. J Biol Chem 2007;282:12119-26. (Pubitemid 47100718)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 12119-12126
-
-
Hong, S.1
Wang, L.-C.2
Gao, X.3
Kuo, Y.-L.4
Liu, B.5
Merling, R.6
Kung, H.-J.7
Shih, H.-M.8
Giam, C.-Z.9
-
17
-
-
38749091638
-
PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: A mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment
-
Guénin S, Schwartz L, Morvan D, et al. PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment. Int J Oncol 2008;32:49-57. (Pubitemid 351176061)
-
(2008)
International Journal of Oncology
, vol.32
, Issue.1
, pp. 49-57
-
-
Guenin, S.1
Schwartz, L.2
Morvan, D.3
Steyaert, J.M.4
Poignet, A.5
Madelmont, J.C.6
Demidem, A.7
-
18
-
-
34447283580
-
CIP2A Inhibits PP2A in Human Malignancies
-
DOI 10.1016/j.cell.2007.04.044, PII S0092867407006666
-
Junttila MR, Puustinen P, Niemela M, et al. CIP2A inhibits PP2A in human malignancies. Cell 2007;130:51-62. (Pubitemid 47039258)
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 51-62
-
-
Junttila, M.R.1
Puustinen, P.2
Niemela, M.3
Ahola, R.4
Arnold, H.5
Bottzauw, T.6
Ala-aho, R.7
Nielsen, C.8
Ivaska, J.9
Taya, Y.10
Lu, S.-L.11
Lin, S.12
Chan, E.K.L.13
Wang, X.-J.14
Grenman, R.15
Kast, J.16
Kallunki, T.17
Sears, R.18
Kahari, V.-M.19
Westermarck, J.20
more..
-
19
-
-
69349102025
-
CIP2A is associated with human breast cancer aggressivity
-
Come C, Laine A, Chanrion M, et al. CIP2A is associated with human breast cancer aggressivity. J Clin Cancer Res 2009;15:5092-5100.
-
(2009)
J Clin Cancer Res
, vol.15
, pp. 5092-5100
-
-
Come, C.1
Laine, A.2
Chanrion, M.3
-
20
-
-
76649101395
-
Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERKpathways
-
Zhao D, Liu Z, Ding J, et al. Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERKpathways. J Med Microbiol 2010;59:259-65.
-
(2010)
J Med Microbiol
, vol.59
, pp. 259-265
-
-
Zhao, D.1
Liu, Z.2
Ding, J.3
-
21
-
-
27644569730
-
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
-
DOI 10.1016/j.ccr.2005.10.015, PII S1535610805003363
-
Neviani P, Santhanam R, Trotta R, et al. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer Cell 2005;8:355-68. (Pubitemid 41579831)
-
(2005)
Cancer Cell
, vol.8
, Issue.5
, pp. 355-368
-
-
Neviani, P.1
Santhanam, R.2
Trotta, R.3
Notari, M.4
Blaser, B.W.5
Liu, S.6
Mao, H.7
Chang, J.S.8
Galietta, A.9
Uttam, A.10
Roy, D.C.11
Valtieri, M.12
Bruner-Klisovic, R.13
Caligiuri, M.A.14
Bloomfield, C.D.15
Marcucci, G.16
Perrotti, D.17
-
22
-
-
79959829735
-
α4 is highly expressed in carcinogentransformed human cells and primary human cancers
-
Chen LP, Lai YD, Li DC, et al. α4 is highly expressed in carcinogentransformed human cells and primary human cancers. Oncogene 2011;20:2943-53.
-
(2011)
Oncogene
, vol.20
, pp. 2943-2953
-
-
Chen, L.P.1
Lai, Y.D.2
Li, D.C.3
-
23
-
-
0033881446
-
Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A
-
Marcellus RC, Chan H, Paquette D, et al. Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A. J Virof 2000;74:7869-87.
-
(2000)
J Virof
, vol.74
, pp. 7869-7887
-
-
Marcellus, R.C.1
Chan, H.2
Paquette, D.3
-
24
-
-
0036324663
-
Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein
-
DOI 10.1083/jcb.200201106
-
Robert A, Miron MJ, Champagne C, et al. Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein. J Cell Biol 2002;158:519-28. (Pubitemid 34851710)
-
(2002)
Journal of Cell Biology
, vol.158
, Issue.3
, pp. 519-528
-
-
Robert, A.1
Miron, M.-J.2
Champagne, C.3
Gingras, M.-C.4
Branton, P.E.5
Lavoie, J.N.6
-
25
-
-
17444407035
-
Tumour therapy with genes encoding apoptin and E4orf4
-
Mitrus I, Missol-Kolka E, Piucienniczak A, Szala S. Tumour therapy with genes encoding apoptin and E4orf4. Anticancer Res 2005;25:1087-90. (Pubitemid 40546885)
-
(2005)
Anticancer Research
, vol.25
, Issue.2 A
, pp. 1087-1090
-
-
Mitrus, I.1
Missol-Kolka, E.2
Plucienniczak, A.3
Szala, S.4
-
26
-
-
34648832173
-
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia
-
DOI 10.1172/JCI31095
-
Neviani P, Santhanam R, Oaks JJ, et al. FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosomepositive acute lymphocytic leukemia. J Clin Invest 2007;117:2408-21. (Pubitemid 47494343)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2408-2421
-
-
Neviani, P.1
Santhanam, R.2
Oaks, J.J.3
Eiring, A.M.4
Notari, M.5
Blaser, B.W.6
Liu, S.7
Trotta, R.8
Muthusamy, N.9
Gambacorti-Passerini, C.10
Druker, B.J.11
Cortes, J.12
Marcucci, G.13
Chen, C.-S.14
Verrills, N.M.15
Roy, D.C.16
Caligiuri, M.A.17
Bloomfield, C.D.18
Byrd, J.C.19
Perrotti, D.20
more..
-
27
-
-
0037739755
-
A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells
-
DOI 10.1038/sj.bjp.0705182
-
Matsuoka Y, Nagahara Y, Ikekita M, Shinomiya T. A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells. Br J Pharmacol 2003;138:1303-12. (Pubitemid 36543128)
-
(2003)
British Journal of Pharmacology
, vol.138
, Issue.7
, pp. 1303-1312
-
-
Matsuoka, Y.1
Nagahara, Y.2
Ikekita, M.3
Shinomiya, T.4
-
28
-
-
33645099459
-
Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology
-
Guergnon J, Dessauge F, Dominguez V, et al. Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology. Mot Pharmacol 2006;69:1115-24.
-
(2006)
Mot Pharmacol
, vol.69
, pp. 1115-1124
-
-
Guergnon, J.1
Dessauge, F.2
Dominguez, V.3
-
29
-
-
77956321594
-
x (0, 1) V/lxFxx (R/K) x (R/K) is a new apoptotic signature
-
x (0, 1) V/lxFxx (R/K) x (R/K) is a new apoptotic signature. PloS One 2010;5:e9981.
-
(2010)
PloS One
, vol.5
-
-
Godet, A.N.1
Guergnon, J.2
Maire, V.3
|