메뉴 건너뛰기




Volumn 40, Issue 2, 2012, Pages 97-106

Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; DIPROTIN A; SITAGLIPTIN;

EID: 84855610542     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2011.10.010     Document Type: Article
Times cited : (8)

References (47)
  • 1
    • 77957576120 scopus 로고    scopus 로고
    • Transplantation tolerance through mixed chimerism
    • Pilat N., Wekerle T. Transplantation tolerance through mixed chimerism. Nat Rev Nephrol 2010, 6:594-605.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 594-605
    • Pilat, N.1    Wekerle, T.2
  • 2
    • 38549088096 scopus 로고    scopus 로고
    • HLA-mismatched renal transplantation without maintenance immunosuppression
    • Kawai T., Cosimi A.B., Spitzer T.R., et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008, 358:353-361.
    • (2008) N Engl J Med , vol.358 , pp. 353-361
    • Kawai, T.1    Cosimi, A.B.2    Spitzer, T.R.3
  • 3
    • 55649124879 scopus 로고    scopus 로고
    • Clinical experience with mixed chimerism to induce transplantation tolerance
    • Fehr T., Sykes M. Clinical experience with mixed chimerism to induce transplantation tolerance. Transpl Int 2008, 21:1118-1135.
    • (2008) Transpl Int , vol.21 , pp. 1118-1135
    • Fehr, T.1    Sykes, M.2
  • 4
    • 67649892543 scopus 로고    scopus 로고
    • Hurdles to the induction of tolerogenic mixed chimerism
    • Pilat N., Klaus C., Schwaiger E., Wekerle T. Hurdles to the induction of tolerogenic mixed chimerism. Transplantation 2009, 87(Suppl):S79-S84.
    • (2009) Transplantation , vol.87 , Issue.SUPPL.
    • Pilat, N.1    Klaus, C.2    Schwaiger, E.3    Wekerle, T.4
  • 5
    • 23944502334 scopus 로고    scopus 로고
    • Costimulation blockade with belatacept in renal transplantation
    • Vincenti F., Larsen C., Durrbach A., et al. Costimulation blockade with belatacept in renal transplantation. N Engl J Med 2005, 353:770-781.
    • (2005) N Engl J Med , vol.353 , pp. 770-781
    • Vincenti, F.1    Larsen, C.2    Durrbach, A.3
  • 6
    • 33645890847 scopus 로고    scopus 로고
    • New approaches to prevent transplant rejection: costimulation blockers anti-CD40L and CTLA4Ig
    • Pree I., Wekerle T. New approaches to prevent transplant rejection: costimulation blockers anti-CD40L and CTLA4Ig. Drug Discov Today Ther Strateg 2006, 3:41-47.
    • (2006) Drug Discov Today Ther Strateg , vol.3 , pp. 41-47
    • Pree, I.1    Wekerle, T.2
  • 7
    • 0032526283 scopus 로고    scopus 로고
    • Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
    • Wekerle T., Sayegh M.H., Hill J., et al. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J Exp Med 1998, 187:2037-2044.
    • (1998) J Exp Med , vol.187 , pp. 2037-2044
    • Wekerle, T.1    Sayegh, M.H.2    Hill, J.3
  • 8
    • 0034071426 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment
    • Wekerle T., Kurtz J., Ito H., et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med 2000, 6:464-469.
    • (2000) Nat Med , vol.6 , pp. 464-469
    • Wekerle, T.1    Kurtz, J.2    Ito, H.3
  • 9
    • 0035879193 scopus 로고    scopus 로고
    • Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression
    • Adams A.B., Durham M.M., Kean L., et al. Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression. J Immunol 2001, 167:1103-1111.
    • (2001) J Immunol , vol.167 , pp. 1103-1111
    • Adams, A.B.1    Durham, M.M.2    Kean, L.3
  • 10
    • 0036402128 scopus 로고    scopus 로고
    • H2-mismatched transplantation with repetitive cell infusions and CD40 ligand antibody infusions without myeloablation
    • Lambert J.F., Colvin G.A., Zhong S., et al. H2-mismatched transplantation with repetitive cell infusions and CD40 ligand antibody infusions without myeloablation. Br J Haematol 2002, 119:155-163.
    • (2002) Br J Haematol , vol.119 , pp. 155-163
    • Lambert, J.F.1    Colvin, G.A.2    Zhong, S.3
  • 11
    • 0035746174 scopus 로고    scopus 로고
    • Tolerance through bone marrow transplantation with costimulation blockade
    • Wekerle T., Blaha P., Langer F., Schmid M., Muehlbacher F. Tolerance through bone marrow transplantation with costimulation blockade. Transpl Immunol 2002, 9:125-133.
    • (2002) Transpl Immunol , vol.9 , pp. 125-133
    • Wekerle, T.1    Blaha, P.2    Langer, F.3    Schmid, M.4    Muehlbacher, F.5
  • 12
    • 0038576227 scopus 로고    scopus 로고
    • The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade
    • Blaha P., Bigenzahn S., Koporc Z., et al. The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood 2003, 101:2886-2893.
    • (2003) Blood , vol.101 , pp. 2886-2893
    • Blaha, P.1    Bigenzahn, S.2    Koporc, Z.3
  • 13
    • 0036839605 scopus 로고    scopus 로고
    • Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions
    • Taylor P.A., Lees C.J., Wilson J.M., et al. Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions. Blood 2002, 100:3400-3407.
    • (2002) Blood , vol.100 , pp. 3400-3407
    • Taylor, P.A.1    Lees, C.J.2    Wilson, J.M.3
  • 14
    • 77949852097 scopus 로고    scopus 로고
    • Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning
    • Pilat N., Baranyi U., Klaus C., et al. Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning. Am J Transplant 2010, 10:751-762.
    • (2010) Am J Transplant , vol.10 , pp. 751-762
    • Pilat, N.1    Baranyi, U.2    Klaus, C.3
  • 15
    • 33846217342 scopus 로고    scopus 로고
    • Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression
    • Kean L.S., Adams A.B., Strobert E., et al. Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression. Am J Transplant 2007, 7:320-335.
    • (2007) Am J Transplant , vol.7 , pp. 320-335
    • Kean, L.S.1    Adams, A.B.2    Strobert, E.3
  • 16
    • 4344586455 scopus 로고    scopus 로고
    • CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates
    • Kawai T., Sogawa H., Boskovic S., et al. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant 2004, 4:1391-1398.
    • (2004) Am J Transplant , vol.4 , pp. 1391-1398
    • Kawai, T.1    Sogawa, H.2    Boskovic, S.3
  • 17
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled A., Petit I., Kollet O., et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999, 283:845-848.
    • (1999) Science , vol.283 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3
  • 18
    • 0035839639 scopus 로고    scopus 로고
    • Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family
    • Lambeir A.M., Proost P., Durinx C., et al. Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family. J Biol Chem 2001, 276:29839-29845.
    • (2001) J Biol Chem , vol.276 , pp. 29839-29845
    • Lambeir, A.M.1    Proost, P.2    Durinx, C.3
  • 19
    • 0037114177 scopus 로고    scopus 로고
    • Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells
    • Christopherson K.W., Hangoc G., Broxmeyer H.E. Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells. J Immunol 2002, 169:7000-7008.
    • (2002) J Immunol , vol.169 , pp. 7000-7008
    • Christopherson, K.W.1    Hangoc, G.2    Broxmeyer, H.E.3
  • 20
    • 4043117769 scopus 로고    scopus 로고
    • Modulation of hematopoietic stem cell homing and engraftment by CD26
    • Christopherson K.W., Hangoc G., Mantel C.R., Broxmeyer H.E. Modulation of hematopoietic stem cell homing and engraftment by CD26. Science 2004, 305:1000-1003.
    • (2004) Science , vol.305 , pp. 1000-1003
    • Christopherson, K.W.1    Hangoc, G.2    Mantel, C.R.3    Broxmeyer, H.E.4
  • 21
    • 33645108527 scopus 로고    scopus 로고
    • Inhibition of CD26 peptidase activity significantly improves engraftment of retrovirally transduced hematopoietic progenitors
    • Tian C., Bagley J., Forman D., Iacomini J. Inhibition of CD26 peptidase activity significantly improves engraftment of retrovirally transduced hematopoietic progenitors. Gene Ther 2006, 13:652-658.
    • (2006) Gene Ther , vol.13 , pp. 652-658
    • Tian, C.1    Bagley, J.2    Forman, D.3    Iacomini, J.4
  • 22
    • 33845483092 scopus 로고    scopus 로고
    • CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation
    • Peranteau W.H., Endo M., Adibe O.O., Merchant A., Zoltick P.W., Flake A.W. CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation. Blood 2006, 108:4268-4274.
    • (2006) Blood , vol.108 , pp. 4268-4274
    • Peranteau, W.H.1    Endo, M.2    Adibe, O.O.3    Merchant, A.4    Zoltick, P.W.5    Flake, A.W.6
  • 23
    • 34347334543 scopus 로고    scopus 로고
    • CD26 inhibition on CD34+ or lineage-human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice
    • Christopherson K.W., Paganessi L.A., Napier S., Porecha N.K. CD26 inhibition on CD34+ or lineage-human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice. Stem Cells Dev 2007, 16:355-360.
    • (2007) Stem Cells Dev , vol.16 , pp. 355-360
    • Christopherson, K.W.1    Paganessi, L.A.2    Napier, S.3    Porecha, N.K.4
  • 24
    • 34347325114 scopus 로고    scopus 로고
    • Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells
    • Kawai T., Choi U., Liu P.C., Whiting-Theobald N.L., Linton G.F., Malech H.L. Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells. Stem Cells Dev 2007, 16:361-370.
    • (2007) Stem Cells Dev , vol.16 , pp. 361-370
    • Kawai, T.1    Choi, U.2    Liu, P.C.3    Whiting-Theobald, N.L.4    Linton, G.F.5    Malech, H.L.6
  • 25
    • 34347366261 scopus 로고    scopus 로고
    • Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice
    • Campbell T.B., Hangoc G., Liu Y., Pollok K., Broxmeyer H.E. Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells Dev 2007, 16:347-354.
    • (2007) Stem Cells Dev , vol.16 , pp. 347-354
    • Campbell, T.B.1    Hangoc, G.2    Liu, Y.3    Pollok, K.4    Broxmeyer, H.E.5
  • 26
    • 17144446373 scopus 로고    scopus 로고
    • Inhibition of CD26/dipeptidyl peptidase IV activity invivo prolongs cardiac allograft survival in rat recipients
    • Korom S., De Meester I., Stadlbauer T.H., et al. Inhibition of CD26/dipeptidyl peptidase IV activity invivo prolongs cardiac allograft survival in rat recipients. Transplantation 1997, 63:1495-1500.
    • (1997) Transplantation , vol.63 , pp. 1495-1500
    • Korom, S.1    De Meester, I.2    Stadlbauer, T.H.3
  • 27
    • 33748163907 scopus 로고    scopus 로고
    • CD26/dipeptidylpeptidase IV-targeted therapy of acute lung rejection in rats
    • Jung F.J., Yang L., De Meester I., et al. CD26/dipeptidylpeptidase IV-targeted therapy of acute lung rejection in rats. J Heart Lung Transplant 2006, 25:1109-1116.
    • (2006) J Heart Lung Transplant , vol.25 , pp. 1109-1116
    • Jung, F.J.1    Yang, L.2    De Meester, I.3
  • 28
    • 33845467401 scopus 로고    scopus 로고
    • Ischemia/reperfusion injury: the role of CD26/dipeptidyl-peptidase-IV-inhibition in lung transplantation
    • Zhai W., Cardell M., De Meester I., et al. Ischemia/reperfusion injury: the role of CD26/dipeptidyl-peptidase-IV-inhibition in lung transplantation. Transplant Proc 2006, 38:3369-3371.
    • (2006) Transplant Proc , vol.38 , pp. 3369-3371
    • Zhai, W.1    Cardell, M.2    De Meester, I.3
  • 29
    • 0037787851 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV
    • Lambeir A.M., Durinx C., Scharpe S., De Meester I. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit Rev Clin Lab Sci 2003, 40:209-294.
    • (2003) Crit Rev Clin Lab Sci , vol.40 , pp. 209-294
    • Lambeir, A.M.1    Durinx, C.2    Scharpe, S.3    De Meester, I.4
  • 30
    • 17144404555 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    • Gorrell M.D. Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin Sci (Lond) 2005, 108:277-292.
    • (2005) Clin Sci (Lond) , vol.108 , pp. 277-292
    • Gorrell, M.D.1
  • 31
    • 0027270023 scopus 로고
    • The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity
    • Tanaka T., Kameoka J., Yaron A., Schlossman S.F., Morimoto C. The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity. Proc Natl Acad Sci U S A 1993, 90:4586-4590.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4586-4590
    • Tanaka, T.1    Kameoka, J.2    Yaron, A.3    Schlossman, S.F.4    Morimoto, C.5
  • 32
    • 0027215591 scopus 로고
    • Cloning and functional expression of the T cell activation antigen CD26
    • Tanaka T. Cloning and functional expression of the T cell activation antigen CD26. J Immunol 1993, 150:2090.
    • (1993) J Immunol , vol.150 , pp. 2090
    • Tanaka, T.1
  • 33
    • 70349326304 scopus 로고    scopus 로고
    • A CD26-controlled cell surface cascade for regulation of T cell motility and chemokine signals
    • Liu Z., Christensson M., Forslow A., De Meester I., Sundqvist K.G. A CD26-controlled cell surface cascade for regulation of T cell motility and chemokine signals. J Immunol 2009, 183:3616-3624.
    • (2009) J Immunol , vol.183 , pp. 3616-3624
    • Liu, Z.1    Christensson, M.2    Forslow, A.3    De Meester, I.4    Sundqvist, K.G.5
  • 34
    • 44549085494 scopus 로고    scopus 로고
    • Revisiting an old acquaintance: CD26 and its molecular mechanisms in T cell function
    • Ohnuma K., Dang N.H., Morimoto C. Revisiting an old acquaintance: CD26 and its molecular mechanisms in T cell function. Trends Immunol 2008, 29:295-301.
    • (2008) Trends Immunol , vol.29 , pp. 295-301
    • Ohnuma, K.1    Dang, N.H.2    Morimoto, C.3
  • 36
    • 33244488261 scopus 로고    scopus 로고
    • Induction of mixed chimerism through transplantation of CD45-congenic mobilized peripheral blood stem cells after nonmyeloablative irradiation
    • Koporc Z., Bigenzahn S., Blaha P., et al. Induction of mixed chimerism through transplantation of CD45-congenic mobilized peripheral blood stem cells after nonmyeloablative irradiation. Biol Blood Marrow Transplant 2006, 12:284-292.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 284-292
    • Koporc, Z.1    Bigenzahn, S.2    Blaha, P.3
  • 37
    • 0037777665 scopus 로고    scopus 로고
    • Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells
    • Christopherson K.W., Cooper S., Broxmeyer H.E. Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells. Blood 2003, 101:4680-4686.
    • (2003) Blood , vol.101 , pp. 4680-4686
    • Christopherson, K.W.1    Cooper, S.2    Broxmeyer, H.E.3
  • 38
    • 34548437672 scopus 로고    scopus 로고
    • AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated bytheSDF-1/CXCL12-CXCR4 axis
    • Broxmeyer H.E., Hangoc G., Cooper S., Campbell T., Ito S., Mantel C. AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated bytheSDF-1/CXCL12-CXCR4 axis. Ann N Y Acad Sci 2007, 1106:1-19.
    • (2007) Ann N Y Acad Sci , vol.1106 , pp. 1-19
    • Broxmeyer, H.E.1    Hangoc, G.2    Cooper, S.3    Campbell, T.4    Ito, S.5    Mantel, C.6
  • 39
    • 79953320085 scopus 로고    scopus 로고
    • Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
    • Matheeussen V., Baerts L., De Meyer G., et al. Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries. Biol Chem 2011, 392:189-198.
    • (2011) Biol Chem , vol.392 , pp. 189-198
    • Matheeussen, V.1    Baerts, L.2    De Meyer, G.3
  • 40
    • 0024267488 scopus 로고
    • Assay of dipeptidyl peptidase IV in serum by fluorometry of 4-methoxy-2-naphthylamine
    • Scharpe S., De Meester I., Vanhoof G., et al. Assay of dipeptidyl peptidase IV in serum by fluorometry of 4-methoxy-2-naphthylamine. Clin Chem 1988, 34:2299-2301.
    • (1988) Clin Chem , vol.34 , pp. 2299-2301
    • Scharpe, S.1    De Meester, I.2    Vanhoof, G.3
  • 41
    • 1442331657 scopus 로고    scopus 로고
    • Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites
    • Ito H., Takeuchi Y., Shaffer J., Sykes M. Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites. Blood 2004, 103:1949-1954.
    • (2004) Blood , vol.103 , pp. 1949-1954
    • Ito, H.1    Takeuchi, Y.2    Shaffer, J.3    Sykes, M.4
  • 42
    • 33845476757 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone
    • Charbonnel B., Karasik A., Liu J., Wu M., Meininger G. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone. Diabetes Care 2006, 29:2638-2643.
    • (2006) Diabetes Care , vol.29 , pp. 2638-2643
    • Charbonnel, B.1    Karasik, A.2    Liu, J.3    Wu, M.4    Meininger, G.5
  • 43
    • 33746977707 scopus 로고    scopus 로고
    • Sitagliptin: a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    • Miller S., St Onge E.L. Sitagliptin: a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Ann Pharmacother 2006, 40:1336-1343.
    • (2006) Ann Pharmacother , vol.40 , pp. 1336-1343
    • Miller, S.1    St Onge, E.L.2
  • 44
    • 0032103285 scopus 로고    scopus 로고
    • Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4
    • Markees T.G., Phillips N.E., Gordon E.J., et al. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest 1998, 101:2446-2455.
    • (1998) J Clin Invest , vol.101 , pp. 2446-2455
    • Markees, T.G.1    Phillips, N.E.2    Gordon, E.J.3
  • 45
    • 79961026257 scopus 로고    scopus 로고
    • Therapeutic efficacy of polyclonal Tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model
    • Pilat N., Klaus C., Gattringer M., et al. Therapeutic efficacy of polyclonal Tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model. Transplantation 2011, 92:280-288.
    • (2011) Transplantation , vol.92 , pp. 280-288
    • Pilat, N.1    Klaus, C.2    Gattringer, M.3
  • 46
    • 25844459084 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9
    • Lankas G.R., Leiting B., Roy R.S., et al. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes 2005, 54:2988-2994.
    • (2005) Diabetes , vol.54 , pp. 2988-2994
    • Lankas, G.R.1    Leiting, B.2    Roy, R.S.3
  • 47
    • 48449086945 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice
    • Kim S.J., Nian C., Doudet D.J., McIntosh C.H. Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice. Diabetes 2008, 57:1331-1339.
    • (2008) Diabetes , vol.57 , pp. 1331-1339
    • Kim, S.J.1    Nian, C.2    Doudet, D.J.3    McIntosh, C.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.