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Volumn 57, Issue 5, 2008, Pages 1331-1339

Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; SITAGLIPTIN; ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; PYRAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

EID: 48449086945     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db07-1639     Document Type: Article
Times cited : (80)

References (40)
  • 2
    • 64549106249 scopus 로고    scopus 로고
    • Collaborative Islet Transplant Registry Annual Reports [article online]. Available from https://web.emmes.com/study/isl/reports/reports.htm. Accessed 20 December 2007
    • Collaborative Islet Transplant Registry Annual Reports [article online]. Available from https://web.emmes.com/study/isl/reports/reports.htm. Accessed 20 December 2007
  • 5
    • 0036924904 scopus 로고    scopus 로고
    • Intrahepatically transplanted islets-strangers in a strange land [Editorial]
    • Robertson RP: Intrahepatically transplanted islets-strangers in a strange land [Editorial]. Endocrinology 8:5416-5417, 2002
    • (2002) Endocrinology , vol.8 , pp. 5416-5417
    • Robertson, R.P.1
  • 6
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttrransplantation period: Dynamic changes in structure and function
    • Davalli AM, Scaglia L, Zangen DH, Hollister J, Bonner-Weir S, Weir GC: Vulnerability of islets in the immediate posttrransplantation period: dynamic changes in structure and function. Diabetes 45:1161-1167, 1996
    • (1996) Diabetes , vol.45 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 7
    • 33646735392 scopus 로고    scopus 로고
    • Biological and biomaterial approaches for improved islet transplantation
    • Narang AS, Mahato RI: Biological and biomaterial approaches for improved islet transplantation. Pharmacol Rev 58:194-243, 2006
    • (2006) Pharmacol Rev , vol.58 , pp. 194-243
    • Narang, A.S.1    Mahato, R.I.2
  • 8
    • 2542479899 scopus 로고    scopus 로고
    • Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
    • Brubaker PL, Drucker DJ: Minireview: glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 145:2653-2659, 2004
    • (2004) Endocrinology , vol.145 , pp. 2653-2659
    • Brubaker, P.L.1    Drucker, D.J.2
  • 9
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker DJ: The biology of incretin hormones. Cell Metab 3:153-165, 2006
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 10
    • 0141785429 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypep-tide promotes beta-(INS-1) cell survival via cyclic adenosine monophos-phate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase
    • Ehses JA, Casilla VR, Doty T, Pospisilik JA, Winter KD, Demuth HU, Pederson RA, McIntosh CHS: Glucose-dependent insulinotropic polypep-tide promotes beta-(INS-1) cell survival via cyclic adenosine monophos-phate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase. Endocrinology 144:4433-4445, 2003
    • (2003) Endocrinology , vol.144 , pp. 4433-4445
    • Ehses, J.A.1    Casilla, V.R.2    Doty, T.3    Pospisilik, J.A.4    Winter, K.D.5    Demuth, H.U.6    Pederson, R.A.7    McIntosh, C.H.S.8
  • 11
    • 20444491588 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/ protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression
    • Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CHS: Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/ protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression. J Biol Chem 280:22297-22307, 2005
    • (2005) J Biol Chem , vol.280 , pp. 22297-22307
    • Kim, S.J.1    Winter, K.2    Nian, C.3    Tsuneoka, M.4    Koda, Y.5    McIntosh, C.H.S.6
  • 12
    • 40749157994 scopus 로고    scopus 로고
    • Glucose-dependent insuli-notropic polypeptide (GIP) mediated up-regulation of β-cell antiapoptotic Bcl-2 gene expression is coordinated by cAMP-response element binding protein (CREB) and cAMP-responsive CREB coactivator 2 (TORC2)
    • Kim SJ, Nian C, Widenmaier S, McIntosh CHS: Glucose-dependent insuli-notropic polypeptide (GIP) mediated up-regulation of β-cell antiapoptotic Bcl-2 gene expression is coordinated by cAMP-response element binding protein (CREB) and cAMP-responsive CREB coactivator 2 (TORC2). Mol Cell Biol 28:1644-1656, 2008
    • (2008) Mol Cell Biol , vol.28 , pp. 1644-1656
    • Kim, S.J.1    Nian, C.2    Widenmaier, S.3    McIntosh, C.H.S.4
  • 13
    • 0027215348 scopus 로고
    • Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, pep-tide histidine methionine and is responsible for their degradation in human serum
    • Mentlein R, Gallwitz B, Schmidt WE: Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, pep-tide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem 214:829-835, 1993
    • (1993) Eur J Biochem , vol.214 , pp. 829-835
    • Mentlein, R.1    Gallwitz, B.2    Schmidt, W.E.3
  • 14
    • 0029118049 scopus 로고
    • Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
    • Kieffer TJ, McIntosh CHS, Pederson RA: Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology 136:3585-3596, 1995
    • (1995) Endocrinology , vol.136 , pp. 3585-3596
    • Kieffer, T.J.1    McIntosh, C.H.S.2    Pederson, R.A.3
  • 15
    • 0028953577 scopus 로고
    • Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
    • Deacon CF, Johnsen AH, Holst JJ: Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. J Clin Endocrinol Metab 80:952-957, 1995
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 952-957
    • Deacon, C.F.1    Johnsen, A.H.2    Holst, J.J.3
  • 16
    • 0037787851 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV
    • Lambeir AM, Durinx C, Scharpe S, De Meester I: Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit Rev Clin Lab Sc 40:209-294, 2003
    • (2003) Crit Rev Clin Lab Sc , vol.40 , pp. 209-294
    • Lambeir, A.M.1    Durinx, C.2    Scharpe, S.3    De Meester, I.4
  • 18
    • 34249868446 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors: Clinical data and clinical implications
    • Ahrén B: Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications. Diabetes Care 30:1344-1350, 2007
    • (2007) Diabetes Care , vol.30 , pp. 1344-1350
    • Ahrén, B.1
  • 19
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA: The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 368:1696-1705, 2006
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 20
    • 0029954211 scopus 로고    scopus 로고
    • Creutzfeldt WO, Kleine N, Willms B, 0rskov C, Holst JJ, Nauck MA: Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. Diabetes Care 19:580-586, 1996
    • Creutzfeldt WO, Kleine N, Willms B, 0rskov C, Holst JJ, Nauck MA: Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. Diabetes Care 19:580-586, 1996
  • 21
    • 15044357070 scopus 로고    scopus 로고
    • Glycaemic effects of incretins in type 1 diabetes mellitus: A concise review, with emphasis on studies in humans
    • Dupre J: Glycaemic effects of incretins in type 1 diabetes mellitus: a concise review, with emphasis on studies in humans. Regul Pept 128:149-157, 2005
    • (2005) Regul Pept , vol.128 , pp. 149-157
    • Dupre, J.1
  • 24
    • 19944427998 scopus 로고    scopus 로고
    • Kim D, Wang L, Beconi M, Eiermann GJ, Fisher MH, He H, Hickey GJ, Kowalchick JE, Leiting B, Lyons K, Marsilio F, McCann ME, Patel RA, Petrov A, Scapin G, Patel SB, Roy RS, Wu JK, Wyvratt MJ, Zhang BB, Zhu L, Thornberry NA, Weber AE: (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J Med Chem 48:141-151, 2005
    • Kim D, Wang L, Beconi M, Eiermann GJ, Fisher MH, He H, Hickey GJ, Kowalchick JE, Leiting B, Lyons K, Marsilio F, McCann ME, Patel RA, Petrov A, Scapin G, Patel SB, Roy RS, Wu JK, Wyvratt MJ, Zhang BB, Zhu L, Thornberry NA, Weber AE: (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J Med Chem 48:141-151, 2005
  • 27
    • 64549086471 scopus 로고    scopus 로고
    • Kim SJ, Doudet DJ, Studenov AR, Ruth TJ, Gambhir SS, McIntosh CHS: Seeing is believing-in vivo functional real-time imaging of transplanted islets using positron emission tomography (PET). DOI: 10.1038/ nprot.2006.491 [article online]. Nature Protocols Network. Available from: http://www.natureprotocols. com/2006/12/21/seeing-is-believing-in-vivo-fu.php
    • Kim SJ, Doudet DJ, Studenov AR, Ruth TJ, Gambhir SS, McIntosh CHS: Seeing is believing-in vivo functional real-time imaging of transplanted islets using positron emission tomography (PET). DOI: 10.1038/ nprot.2006.491 [article online]. Nature Protocols Network. Available from: http://www.natureprotocols. com/2006/12/21/seeing-is-believing-in-vivo-fu.php
  • 28
    • 33845532052 scopus 로고    scopus 로고
    • Quantitative in vivo imaging of transplanted islets using microPET (positron emission tomography) scanning
    • Kim SJ, Doudet DJ, Studenov AR, Ruth TJ, Gambhir SS, McIntosh CHS: Quantitative in vivo imaging of transplanted islets using microPET (positron emission tomography) scanning. Nat Med 12:1423-1428, 2006
    • (2006) Nat Med , vol.12 , pp. 1423-1428
    • Kim, S.J.1    Doudet, D.J.2    Studenov, A.R.3    Ruth, T.J.4    Gambhir, S.S.5    McIntosh, C.H.S.6
  • 31
    • 0034178295 scopus 로고    scopus 로고
    • Comparison of 3-D maximum a posteriori and filtered back projection algorithms for high-resolution animal imaging with microPET
    • Chatziioannou A, Qi J, Moore A, Annala A, Nguyen K, Leahy R, Cherry SR: Comparison of 3-D maximum a posteriori and filtered back projection algorithms for high-resolution animal imaging with microPET. IEEE Trans Med Imag 19:507-512, 2000
    • (2000) IEEE Trans Med Imag , vol.19 , pp. 507-512
    • Chatziioannou, A.1    Qi, J.2    Moore, A.3    Annala, A.4    Nguyen, K.5    Leahy, R.6    Cherry, S.R.7
  • 32
    • 28044464932 scopus 로고    scopus 로고
    • Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo
    • Richards SK, Parton LE, Leclerc I, Rutter GA, Smith RM: Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo. J Endocrinol 187:225-235, 2005
    • (2005) J Endocrinol , vol.187 , pp. 225-235
    • Richards, S.K.1    Parton, L.E.2    Leclerc, I.3    Rutter, G.A.4    Smith, R.M.5
  • 35
    • 31044450746 scopus 로고    scopus 로고
    • Streptozotocin-induced diabetes in large animals (pigs/primates): Role of GLUT2 transporter and β-cell plasticity
    • Dufrane D, van Steenberghe M, Guiot Y, Goebbels R-M, Sakiez A, Gianello P: Streptozotocin-induced diabetes in large animals (pigs/primates): role of GLUT2 transporter and β-cell plasticity. Transplantation 81:36-45, 2006
    • (2006) Transplantation , vol.81 , pp. 36-45
    • Dufrane, D.1    van Steenberghe, M.2    Guiot, Y.3    Goebbels, R.-M.4    Sakiez, A.5    Gianello, P.6
  • 36
    • 34948899336 scopus 로고    scopus 로고
    • Estimation of β-cell mass by metabolic tests: Necessary, but how sufficient?
    • Robertson RP: Estimation of β-cell mass by metabolic tests: necessary, but how sufficient? Diabetes 56:2420-2424, 2007
    • (2007) Diabetes , vol.56 , pp. 2420-2424
    • Robertson, R.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.