메뉴 건너뛰기




Volumn 21, Issue 12, 2008, Pages 1118-1135

Clinical experience with mixed chimerism to induce transplantation tolerance

Author keywords

Bone marrow transplantation; Clinical trial; Mixed chimerism; Myeloma; Tolerance

Indexed keywords

CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUDARABINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SIPLIZUMAB; THYMOCYTE ANTIBODY;

EID: 55649124879     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2008.00783.x     Document Type: Review
Times cited : (62)

References (95)
  • 1
    • 0033518231 scopus 로고    scopus 로고
    • Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant
    • Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999 341 : 1725.
    • (1999) N Engl J Med , vol.341 , pp. 1725
    • Wolfe, R.A.1    Ashby, V.B.2    Milford, E.L.3
  • 2
    • 70449215374 scopus 로고
    • Kidney transplantation between seven pairs of identical twins
    • Murray JE, Merrill JP, Harrison JH. Kidney transplantation between seven pairs of identical twins. Ann Surg 1958 148 : 343.
    • (1958) Ann Surg , vol.148 , pp. 343
    • Murray, J.E.1    Merrill, J.P.2    Harrison, J.H.3
  • 5
    • 42149137365 scopus 로고    scopus 로고
    • Cold ischemia is a major determinant of acute rejection and renal graft survival in the modern era of immunosuppression
    • Mikhalski D, Wissing KM, Ghisdal L, et al. Cold ischemia is a major determinant of acute rejection and renal graft survival in the modern era of immunosuppression. Transplantation 2008 85 : S3.
    • (2008) Transplantation , vol.85
    • Mikhalski, D.1    Wissing, K.M.2    Ghisdal, L.3
  • 6
    • 0035874547 scopus 로고    scopus 로고
    • Intra-bone marrow injection of allogeneic bone marrow cells: A powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice
    • Kushida T, Inaba M, Hisha H, et al. Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice. Blood 2001 97 : 3292.
    • (2001) Blood , vol.97 , pp. 3292
    • Kushida, T.1    Inaba, M.2    Hisha, H.3
  • 7
    • 0034718372 scopus 로고    scopus 로고
    • Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem-cell transplantation: A phase I study
    • Traynor AE, Schroeder J, Rosa RM, et al. Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem-cell transplantation: a phase I study. Lancet 2000 356 : 701.
    • (2000) Lancet , vol.356 , pp. 701
    • Traynor, A.E.1    Schroeder, J.2    Rosa, R.M.3
  • 8
    • 0842310011 scopus 로고    scopus 로고
    • Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity
    • Nikolic B, Takeuchi Y, Leykin I, Fudaba Y, Smith RN, Sykes M. Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity. Diabetes 2004 53 : 376.
    • (2004) Diabetes , vol.53 , pp. 376
    • Nikolic, B.1    Takeuchi, Y.2    Leykin, I.3    Fudaba, Y.4    Smith, R.N.5    Sykes, M.6
  • 9
    • 33744765798 scopus 로고    scopus 로고
    • Bone marrow transplantation attenuates murine IgA nephropathy: Role of a stem cell disorder
    • Imasawa T, Nagasawa R, Utsunomiya Y, et al. Bone marrow transplantation attenuates murine IgA nephropathy: role of a stem cell disorder. Kidney Int 1999 56 : 1809.
    • (1999) Kidney Int , vol.56 , pp. 1809
    • Imasawa, T.1    Nagasawa, R.2    Utsunomiya, Y.3
  • 10
    • 0027310882 scopus 로고
    • Evidence that improved late renal transplant outcome correlates with the development of in vitro donor antigen-specific hyporeactivity
    • Reinsmoen NL, Matas AJ. Evidence that improved late renal transplant outcome correlates with the development of in vitro donor antigen-specific hyporeactivity. Transplantation 1993 55 : 1017.
    • (1993) Transplantation , vol.55 , pp. 1017
    • Reinsmoen, N.L.1    Matas, A.J.2
  • 12
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M. Mixed chimerism and transplant tolerance. Immunity 2001 14 : 417.
    • (2001) Immunity , vol.14 , pp. 417
    • Sykes, M.1
  • 14
    • 0035672484 scopus 로고    scopus 로고
    • STEALTH matters: A novel paradigm of durable primate allograft tolerance
    • Thomas JM, Hubbard WJ, Sooudi SK, Thomas FT. STEALTH matters: a novel paradigm of durable primate allograft tolerance. Immunol Rev 2001 183 : 223.
    • (2001) Immunol Rev , vol.183 , pp. 223
    • Thomas, J.M.1    Hubbard, W.J.2    Sooudi, S.K.3    Thomas, F.T.4
  • 15
    • 14544294574 scopus 로고    scopus 로고
    • Use of skin grafting to demonstrate tolerance before kidney transplantation without immunosuppression in the recipient of a previous bone marrow transplant
    • Ravanan R, Dudley CR, Smith RM, Burton CJ, Lear PA, Unsworth DJ. Use of skin grafting to demonstrate tolerance before kidney transplantation without immunosuppression in the recipient of a previous bone marrow transplant. Transplantation 2005 79 : 375.
    • (2005) Transplantation , vol.79 , pp. 375
    • Ravanan, R.1    Dudley, C.R.2    Smith, R.M.3    Burton, C.J.4    Lear, P.A.5    Unsworth, D.J.6
  • 16
    • 33645981255 scopus 로고    scopus 로고
    • Skin transplantation to monitor clinical donor-related tolerance in mixed hematopoietic chimerism
    • Mache CJ, Schwinger W, Spendel S, Zach O, Regauer S, Ring E. Skin transplantation to monitor clinical donor-related tolerance in mixed hematopoietic chimerism. Pediatr Transplant 2006 10 : 128.
    • (2006) Pediatr Transplant , vol.10 , pp. 128
    • MacHe, C.J.1    Schwinger, W.2    Spendel, S.3    Zach, O.4    Regauer, S.5    Ring, E.6
  • 17
    • 33746931587 scopus 로고    scopus 로고
    • Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: In vivo and in vitro analyses
    • Fudaba Y, Spitzer TR, Shaffer J, et al. Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant 2006 6 : 2121.
    • (2006) Am J Transplant , vol.6 , pp. 2121
    • Fudaba, Y.1    Spitzer, T.R.2    Shaffer, J.3
  • 18
    • 33644803882 scopus 로고    scopus 로고
    • Use of skin grafting to demonstrate tolerance before kidney transplantation without immunosuppression in the recipient of a previous bone marrow transplant
    • Fehr T, Bardwell PD, Sykes M. Use of skin grafting to demonstrate tolerance before kidney transplantation without immunosuppression in the recipient of a previous bone marrow transplant. Transplantation 2005 80 : 1359.
    • (2005) Transplantation , vol.80 , pp. 1359
    • Fehr, T.1    Bardwell, P.D.2    Sykes, M.3
  • 19
    • 33746891447 scopus 로고    scopus 로고
    • Should skin grafts be used to test for tolerance?
    • Deeg HJ. Should skin grafts be used to test for tolerance? Pediatr Transplant 2006 10 : 755.
    • (2006) Pediatr Transplant , vol.10 , pp. 755
    • Deeg, H.J.1
  • 20
    • 34250317456 scopus 로고    scopus 로고
    • Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine
    • Shaffer J, Villard J, Means TK, et al. Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine. Exp Hematol 2007 35 : 1140.
    • (2007) Exp Hematol , vol.35 , pp. 1140
    • Shaffer, J.1    Villard, J.2    Means, T.K.3
  • 21
    • 34848857054 scopus 로고    scopus 로고
    • Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance
    • Brouard S, Mansfield E, Braud C, et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A 2007 104 : 15448.
    • (2007) Proc Natl Acad Sci U S a , vol.104 , pp. 15448
    • Brouard, S.1    Mansfield, E.2    Braud, C.3
  • 22
    • 33846252277 scopus 로고    scopus 로고
    • Multiparameter immune profiling of operational tolerance in liver transplantation
    • Martinez-Llordella M, Puig-Pey I, Orlando G, et al. Multiparameter immune profiling of operational tolerance in liver transplantation. Am J Transplant 2007 7 : 309.
    • (2007) Am J Transplant , vol.7 , pp. 309
    • Martinez-Llordella, M.1    Puig-Pey, I.2    Orlando, G.3
  • 23
    • 4544374473 scopus 로고    scopus 로고
    • Tolerance induction in clinical transplantation
    • Fehr T, Sykes M. Tolerance induction in clinical transplantation. Transpl Immunol 2004 13 : 117.
    • (2004) Transpl Immunol , vol.13 , pp. 117
    • Fehr, T.1    Sykes, M.2
  • 25
    • 0028560026 scopus 로고
    • Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation
    • Helg C, Chapuis B, Bolle JF, et al. Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation. Transplantation 1994 58 : 1420.
    • (1994) Transplantation , vol.58 , pp. 1420
    • Helg, C.1    Chapuis, B.2    Bolle, J.F.3
  • 26
    • 23444459237 scopus 로고
    • Tolerance to an HLA-B,DR disparate kidney allograft after bone-marrow transplantation from same donor
    • Jacobsen N, Taaning E, Ladefoged J, Kristensen JK, Pedersen FK. Tolerance to an HLA-B,DR disparate kidney allograft after bone-marrow transplantation from same donor. Lancet 1994 343 : 800.
    • (1994) Lancet , vol.343 , pp. 800
    • Jacobsen, N.1    Taaning, E.2    Ladefoged, J.3    Kristensen, J.K.4    Pedersen, F.K.5
  • 27
    • 0029033078 scopus 로고
    • Renal transplantation without chronic immunosuppression after T cell-depleted, HLA-mismatched bone marrow transplantation
    • Sorof JM, Koerper MA, Portale AA, Potter D, DeSantes K, Cowan M. Renal transplantation without chronic immunosuppression after T cell-depleted, HLA-mismatched bone marrow transplantation. Transplantation 1995 59 : 1633.
    • (1995) Transplantation , vol.59 , pp. 1633
    • Sorof, J.M.1    Koerper, M.A.2    Portale, A.A.3    Potter, D.4    Desantes, K.5    Cowan, M.6
  • 28
    • 0032814930 scopus 로고    scopus 로고
    • Renal transplantation for end-stage renal disease following bone marrow transplantation: A report of six cases, with and without immunosuppression
    • Butcher JA, Hariharan S, Adams MB, Johnson CP, Roza AM, Cohen EP. Renal transplantation for end-stage renal disease following bone marrow transplantation: a report of six cases, with and without immunosuppression. Clin Transplant 1999 13 : 330.
    • (1999) Clin Transplant , vol.13 , pp. 330
    • Butcher, J.A.1    Hariharan, S.2    Adams, M.B.3    Johnson, C.P.4    Roza, A.M.5    Cohen, E.P.6
  • 29
    • 0035875792 scopus 로고    scopus 로고
    • Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-up
    • Sellers MT, Deierhoi MH, Curtis JJ, et al. Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-up. Transplantation 2001 71 : 1681.
    • (2001) Transplantation , vol.71 , pp. 1681
    • Sellers, M.T.1    Deierhoi, M.H.2    Curtis, J.J.3
  • 30
    • 0037356931 scopus 로고    scopus 로고
    • Outcomes of renal transplantation following bone marrow transplantation
    • Hamawi K, Magalhaes-Silverman M, Bertolatus JA. Outcomes of renal transplantation following bone marrow transplantation. Am J Transplant 2003 3 : 301.
    • (2003) Am J Transplant , vol.3 , pp. 301
    • Hamawi, K.1    Magalhaes-Silverman, M.2    Bertolatus, J.A.3
  • 31
    • 0028816806 scopus 로고
    • Transplantation of a lobe of lung from mother to child following previous transplantation with maternal bone marrow
    • Svendsen UG, Aggestrup S, Heilmann C, et al. Transplantation of a lobe of lung from mother to child following previous transplantation with maternal bone marrow. Eur Respir J 1995 8 : 334.
    • (1995) Eur Respir J , vol.8 , pp. 334
    • Svendsen, U.G.1    Aggestrup, S.2    Heilmann, C.3
  • 32
    • 0141544923 scopus 로고    scopus 로고
    • Living donor liver transplantation and tolerance: A potential strategy in cholangiocarcinoma
    • Kadry Z, Mullhaupt B, Renner EL, et al. Living donor liver transplantation and tolerance: a potential strategy in cholangiocarcinoma. Transplantation 2003 76 : 1003.
    • (2003) Transplantation , vol.76 , pp. 1003
    • Kadry, Z.1    Mullhaupt, B.2    Renner, E.L.3
  • 33
    • 0036893468 scopus 로고    scopus 로고
    • Discontinuation of immunosuppression for prevention of kidney graft rejection after receiving a bone marrow transplant from the same HLA identical sibling donor
    • Gajewski JL, Ippoliti C, Ma Y, Champlin R. Discontinuation of immunosuppression for prevention of kidney graft rejection after receiving a bone marrow transplant from the same HLA identical sibling donor. Am J Hematol 2002 71 : 311.
    • (2002) Am J Hematol , vol.71 , pp. 311
    • Gajewski, J.L.1    Ippoliti, C.2    Ma, Y.3    Champlin, R.4
  • 34
    • 0034551674 scopus 로고    scopus 로고
    • Successful stem cell transplantation following orthotopic liver transplantation from the same haploidentical family donor in a girl with hemophagocytic lymphohistiocytosis
    • Matthes-Martin S, Peters C, Konigsrainer A, et al. Successful stem cell transplantation following orthotopic liver transplantation from the same haploidentical family donor in a girl with hemophagocytic lymphohistiocytosis. Blood 2000 96 : 3997.
    • (2000) Blood , vol.96 , pp. 3997
    • Matthes-Martin, S.1    Peters, C.2    Konigsrainer, A.3
  • 35
    • 0342696159 scopus 로고    scopus 로고
    • Transplantation of autologous and allogeneic bone marrow with liver from a cadaveric donor for primary liver cancer
    • Ringden O, Soderdahl G, Mattsson J, et al. Transplantation of autologous and allogeneic bone marrow with liver from a cadaveric donor for primary liver cancer. Transplantation 2000 69 : 2043.
    • (2000) Transplantation , vol.69 , pp. 2043
    • Ringden, O.1    Soderdahl, G.2    Mattsson, J.3
  • 36
    • 0031658155 scopus 로고    scopus 로고
    • Outcomes of recipients of both bone marrow and solid organ transplants. a review
    • Dey B, Sykes M, Spitzer TR. Outcomes of recipients of both bone marrow and solid organ transplants. A review. Medicine (Baltimore) 1998 77 : 355.
    • (1998) Medicine (Baltimore) , vol.77 , pp. 355
    • Dey, B.1    Sykes, M.2    Spitzer, T.R.3
  • 37
    • 34247338572 scopus 로고    scopus 로고
    • Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft
    • Koyama I, Nadazdin O, Boskovic S, et al. Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant 2007 7 : 1055.
    • (2007) Am J Transplant , vol.7 , pp. 1055
    • Koyama, I.1    Nadazdin, O.2    Boskovic, S.3
  • 38
    • 0018654378 scopus 로고
    • Allograft tolerance after total lymphoid irradiation (TLI)
    • Strober S, Slavin S, Gottlieb M, et al. Allograft tolerance after total lymphoid irradiation (TLI). Immunol Rev 1979 46 : 87.
    • (1979) Immunol Rev , vol.46 , pp. 87
    • Strober, S.1    Slavin, S.2    Gottlieb, M.3
  • 39
    • 0021348233 scopus 로고
    • Induction of specific unresponsiveness to heart allografts in mongrel dogs treated with total lymphoid irradiation and antithymocyte globulin
    • Strober S, Modry DL, Hoppe RT, et al. Induction of specific unresponsiveness to heart allografts in mongrel dogs treated with total lymphoid irradiation and antithymocyte globulin. J Immunol 1984 132 : 1013.
    • (1984) J Immunol , vol.132 , pp. 1013
    • Strober, S.1    Modry, D.L.2    Hoppe, R.T.3
  • 41
    • 0019302736 scopus 로고
    • Transplantation tolerance in primates following total lymphoid irradiation and allogeneic bone marrow injection. II. Renal allografts
    • Myburgh JA, Smit JA, Hill RR, Browde S. Transplantation tolerance in primates following total lymphoid irradiation and allogeneic bone marrow injection. II. Renal allografts. Transplantation 1980 29 : 405.
    • (1980) Transplantation , vol.29 , pp. 405
    • Myburgh, J.A.1    Smit, J.A.2    Hill, R.R.3    Browde, S.4
  • 42
    • 0018818630 scopus 로고
    • Transplantation tolerance in primates after total lymphoid irradiation and allogeneic bone marrow injection. III. Lymphocyte responsiveness and suppressor cell activity
    • Smit JA, Hill RR, Myburgh JA, Browde S. Transplantation tolerance in primates after total lymphoid irradiation and allogeneic bone marrow injection. III. Lymphocyte responsiveness and suppressor cell activity. Transplantation 1980 30 : 107.
    • (1980) Transplantation , vol.30 , pp. 107
    • Smit, J.A.1    Hill, R.R.2    Myburgh, J.A.3    Browde, S.4
  • 43
    • 0035959972 scopus 로고    scopus 로고
    • Tolerance in baboon kidney transplantation with total lymphoid irradiation (TLI) and anti-CD3/CD4-idarubicin conjugates
    • Myburgh JA, Smit JA, Pieterz GA, Ling S, Sandrin MS, McKenzie IF. Tolerance in baboon kidney transplantation with total lymphoid irradiation (TLI) and anti-CD3/CD4-idarubicin conjugates. Transplantation 2001 72 : 1150.
    • (2001) Transplantation , vol.72 , pp. 1150
    • Myburgh, J.A.1    Smit, J.A.2    Pieterz, G.A.3    Ling, S.4    Sandrin, M.S.5    McKenzie, I.F.6
  • 44
    • 0024364744 scopus 로고
    • Acquired immune tolerance to cadaveric renal allografts. a study of three patients treated with total lymphoid irradiation
    • Strober S, Dhillon M, Schubert M, et al. Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation. N Engl J Med 1989 321 : 28.
    • (1989) N Engl J Med , vol.321 , pp. 28
    • Strober, S.1    Dhillon, M.2    Schubert, M.3
  • 45
    • 0034720063 scopus 로고    scopus 로고
    • Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: Studies of chimerism and anti-donor reactivity
    • Strober S, Benike C, Krishnaswamy S, Engleman EG, Grumet FC. Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: studies of chimerism and anti-donor reactivity. Transplantation 2000 69 : 1549.
    • (2000) Transplantation , vol.69 , pp. 1549
    • Strober, S.1    Benike, C.2    Krishnaswamy, S.3    Engleman, E.G.4    Grumet, F.C.5
  • 46
    • 0019538224 scopus 로고
    • Transplantation tolerance in the primate following total lymphoid irradiation (TLI) and bone marrow (BM) injection
    • Myburgh JA, Smit JA, Browde S. Transplantation tolerance in the primate following total lymphoid irradiation (TLI) and bone marrow (BM) injection. Transplant Proc 1981 13 : 434.
    • (1981) Transplant Proc , vol.13 , pp. 434
    • Myburgh, J.A.1    Smit, J.A.2    Browde, S.3
  • 47
    • 0030896219 scopus 로고    scopus 로고
    • Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation
    • Storb R, Yu C, Wagner JL, et al. Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation. Blood 1997 89 : 3048.
    • (1997) Blood , vol.89 , pp. 3048
    • Storb, R.1    Yu, C.2    Wagner, J.L.3
  • 48
    • 0033178876 scopus 로고    scopus 로고
    • Stable mixed hematopoietic chimerism in dog leukocyte antigen-identical littermate dogs given lymph node irradiation before and pharmacologic immunosuppression after marrow transplantation
    • Storb R, Yu C, Barnett T, et al. Stable mixed hematopoietic chimerism in dog leukocyte antigen-identical littermate dogs given lymph node irradiation before and pharmacologic immunosuppression after marrow transplantation. Blood 1999 94 : 1131.
    • (1999) Blood , vol.94 , pp. 1131
    • Storb, R.1    Yu, C.2    Barnett, T.3
  • 49
    • 0037093296 scopus 로고    scopus 로고
    • Tolerance to vascularized kidney grafts in canine mixed hematopoietic chimeras
    • Kuhr CS, Allen MD, Junghanss C, et al. Tolerance to vascularized kidney grafts in canine mixed hematopoietic chimeras. Transplantation 2002 73 : 1487.
    • (2002) Transplantation , vol.73 , pp. 1487
    • Kuhr, C.S.1    Allen, M.D.2    Junghanss, C.3
  • 50
    • 34347395540 scopus 로고    scopus 로고
    • Stable trichimerism after marrow grafting from two DLA-identical canine donors and nonmyeloablative conditioning
    • Graves SS, Hogan WJ, Kuhr CS, et al. Stable trichimerism after marrow grafting from two DLA-identical canine donors and nonmyeloablative conditioning. Blood 2007 110 : 412.
    • (2007) Blood , vol.110 , pp. 412
    • Graves, S.S.1    Hogan, W.J.2    Kuhr, C.S.3
  • 51
    • 0024561069 scopus 로고
    • Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen
    • Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 1989 169 : 493.
    • (1989) J Exp Med , vol.169 , pp. 493
    • Sharabi, Y.1    Sachs, D.H.2
  • 53
    • 0033572899 scopus 로고    scopus 로고
    • Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance
    • Kawai T, Poncelet A, Sachs DH, et al. Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance. Transplantation 1999 68 : 1767.
    • (1999) Transplantation , vol.68 , pp. 1767
    • Kawai, T.1    Poncelet, A.2    Sachs, D.H.3
  • 54
    • 4344586455 scopus 로고    scopus 로고
    • CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates
    • Kawai T, Sogawa H, Boskovic S, et al. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant 2004 4 : 1391.
    • (2004) Am J Transplant , vol.4 , pp. 1391
    • Kawai, T.1    Sogawa, H.2    Boskovic, S.3
  • 55
    • 0037096615 scopus 로고    scopus 로고
    • Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeys
    • Kawai T, Cosimi AB, Wee SL, et al. Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeys. Transplantation 2002 73 : 1757.
    • (2002) Transplantation , vol.73 , pp. 1757
    • Kawai, T.1    Cosimi, A.B.2    Wee, S.L.3
  • 56
    • 0028341472 scopus 로고
    • Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen
    • Tomita Y, Khan A, Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen. J Immunol 1994 153 : 1087.
    • (1994) J Immunol , vol.153 , pp. 1087
    • Tomita, Y.1    Khan, A.2    Sykes, M.3
  • 57
    • 0030024697 scopus 로고    scopus 로고
    • Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation
    • Tomita Y, Sachs DH, Khan A, Sykes M. Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation. Transplantation 1996 61 : 469.
    • (1996) Transplantation , vol.61 , pp. 469
    • Tomita, Y.1    Sachs, D.H.2    Khan, A.3    Sykes, M.4
  • 58
    • 0035069856 scopus 로고    scopus 로고
    • Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: The importance of overcoming intrathymic alloresistance
    • Nikolic B, Khan A, Sykes M. Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: the importance of overcoming intrathymic alloresistance. Biol Blood Marrow Transplant 2001 7 : 144.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 144
    • Nikolic, B.1    Khan, A.2    Sykes, M.3
  • 59
    • 0033571542 scopus 로고    scopus 로고
    • Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance
    • Wekerle T, Sayegh MH, Ito H, et al. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance. Transplantation 1999 68 : 1348.
    • (1999) Transplantation , vol.68 , pp. 1348
    • Wekerle, T.1    Sayegh, M.H.2    Ito, H.3
  • 60
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
    • Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med 2000 6 : 114.
    • (2000) Nat Med , vol.6 , pp. 114
    • Kawai, T.1    Andrews, D.2    Colvin, R.B.3    Sachs, D.H.4    Cosimi, A.B.5
  • 61
    • 25444461935 scopus 로고    scopus 로고
    • Protective conditioning for acute graft-versus-host disease
    • Lowsky R, Takahashi T, Liu YP, et al. Protective conditioning for acute graft-versus-host disease. N Engl J Med 2005 353 : 1321.
    • (2005) N Engl J Med , vol.353 , pp. 1321
    • Lowsky, R.1    Takahashi, T.2    Liu, Y.P.3
  • 62
    • 36549078572 scopus 로고    scopus 로고
    • Protective conditioning against GVHD and graft rejection after combined organ and hematopoietic cell transplantation
    • Strober S. Protective conditioning against GVHD and graft rejection after combined organ and hematopoietic cell transplantation. Blood Cells Mol Dis 2008 40 : 48.
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 48
    • Strober, S.1
  • 63
    • 4944246445 scopus 로고    scopus 로고
    • Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning
    • Baron F, Baker JE, Storb R, et al. Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. Blood 2004 104 : 2254.
    • (2004) Blood , vol.104 , pp. 2254
    • Baron, F.1    Baker, J.E.2    Storb, R.3
  • 64
    • 0024209925 scopus 로고
    • Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells
    • Sykes M, Sheard MA, Sachs DH. Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells. J Exp Med 1988 168 : 2391.
    • (1988) J Exp Med , vol.168 , pp. 2391
    • Sykes, M.1    Sheard, M.A.2    Sachs, D.H.3
  • 65
    • 0032617123 scopus 로고    scopus 로고
    • Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen
    • Pelot MR, Pearson DA, Swenson K, et al. Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen. Biol Blood Marrow Transplant 1999 5 : 133.
    • (1999) Biol Blood Marrow Transplant , vol.5 , pp. 133
    • Pelot, M.R.1    Pearson, D.A.2    Swenson, K.3
  • 66
    • 0035544028 scopus 로고    scopus 로고
    • Induction of stable long-term mixed hematopoietic chimerism following nonmyeloablative conditioning with T cell-depleting antibodies, cyclophosphamide, and thymic irradiation leads to donor-specific in vitro and in vivo tolerance
    • Mapara MY, Pelot M, Zhao G, Swenson K, Pearson D, Sykes M. Induction of stable long-term mixed hematopoietic chimerism following nonmyeloablative conditioning with T cell-depleting antibodies, cyclophosphamide, and thymic irradiation leads to donor-specific in vitro and in vivo tolerance. Biol Blood Marrow Transplant 2001 7 : 646.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 646
    • Mapara, M.Y.1    Pelot, M.2    Zhao, G.3    Swenson, K.4    Pearson, D.5    Sykes, M.6
  • 67
    • 33746932816 scopus 로고    scopus 로고
    • An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues
    • Chakraverty R, Cote D, Buchli J, et al. An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med 2006 203 : 2021.
    • (2006) J Exp Med , vol.203 , pp. 2021
    • Chakraverty, R.1    Cote, D.2    Buchli, J.3
  • 68
    • 0036720416 scopus 로고    scopus 로고
    • Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: A critical role for host antigen-presenting cells
    • Mapara MY, Kim YM, Wang SP, Bronson R, Sachs DH, Sykes M. Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood 2002 100 : 1903.
    • (2002) Blood , vol.100 , pp. 1903
    • Mapara, M.Y.1    Kim, Y.M.2    Wang, S.P.3    Bronson, R.4    Sachs, D.H.5    Sykes, M.6
  • 69
    • 0141475940 scopus 로고    scopus 로고
    • Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation
    • Dey BR, McAfee S, Colby C, et al. Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biol Blood Marrow Transplant 2003 9 : 320.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 320
    • Dey, B.R.1    McAfee, S.2    Colby, C.3
  • 70
    • 0033594552 scopus 로고    scopus 로고
    • Mixed lymphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation
    • Sykes M, Preffer F, McAfee S, et al. Mixed lymphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation. Lancet 1999 353 : 1755.
    • (1999) Lancet , vol.353 , pp. 1755
    • Sykes, M.1    Preffer, F.2    McAfee, S.3
  • 71
    • 0033610642 scopus 로고    scopus 로고
    • Selective deletion of antigen-specific, activated T cells by a humanized MAB to CD2 (MEDI-507) is mediated by NK cells
    • Branco L, Barren P, Mao SY, et al. Selective deletion of antigen-specific, activated T cells by a humanized MAB to CD2 (MEDI-507) is mediated by NK cells. Transplantation 1999 68 : 1588.
    • (1999) Transplantation , vol.68 , pp. 1588
    • Branco, L.1    Barren, P.2    Mao, S.Y.3
  • 72
    • 0141596015 scopus 로고    scopus 로고
    • NK cell recovery, chimerism, function, and recognition in recipients of haploidentical hematopoietic cell transplantation following nonmyeloablative conditioning using a humanized anti-CD2 mAb, Medi-507
    • Koenecke C, Shaffer J, Alexander SI, et al. NK cell recovery, chimerism, function, and recognition in recipients of haploidentical hematopoietic cell transplantation following nonmyeloablative conditioning using a humanized anti-CD2 mAb, Medi-507. Exp Hematol 2003 31 : 911.
    • (2003) Exp Hematol , vol.31 , pp. 911
    • Koenecke, C.1    Shaffer, J.2    Alexander, S.I.3
  • 73
    • 20244388936 scopus 로고    scopus 로고
    • Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies
    • Spitzer TR, McAfee SL, Dey BR, et al. Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation 2003 75 : 1748.
    • (2003) Transplantation , vol.75 , pp. 1748
    • Spitzer, T.R.1    McAfee, S.L.2    Dey, B.R.3
  • 74
    • 0000658958 scopus 로고
    • Immunogenetic consequences of vascular anastomoses between bovine twins
    • Owen RD. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 1945 102 : 400.
    • (1945) Science , vol.102 , pp. 400
    • Owen, R.D.1
  • 75
    • 0021251825 scopus 로고
    • Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts
    • Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984 307 : 168.
    • (1984) Nature , vol.307 , pp. 168
    • Ildstad, S.T.1    Sachs, D.H.2
  • 76
    • 0026080585 scopus 로고
    • Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients
    • Barber WH, Mankin JA, Laskow DA, et al. Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients. Transplantation 1991 51 : 70.
    • (1991) Transplantation , vol.51 , pp. 70
    • Barber, W.H.1    Mankin, J.A.2    Laskow, D.A.3
  • 78
    • 0033504043 scopus 로고    scopus 로고
    • Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients
    • Corry RJ, Chakrabarti PK, Shapiro R, et al. Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients. Ann Surg 1999 230 : 372.
    • (1999) Ann Surg , vol.230 , pp. 372
    • Corry, R.J.1    Chakrabarti, P.K.2    Shapiro, R.3
  • 79
    • 0037093290 scopus 로고    scopus 로고
    • Mixed chimerism and immunosuppressive drug withdrawal after HLA-mismatched kidney and hematopoietic progenitor transplantation
    • Millan MT, Shizuru JA, Hoffmann P, et al. Mixed chimerism and immunosuppressive drug withdrawal after HLA-mismatched kidney and hematopoietic progenitor transplantation. Transplantation 2002 73 : 1386.
    • (2002) Transplantation , vol.73 , pp. 1386
    • Millan, M.T.1    Shizuru, J.A.2    Hoffmann, P.3
  • 81
    • 38549134052 scopus 로고    scopus 로고
    • Tolerance and chimerism after renal and hematopoietic-cell transplantation
    • Scandling JD, Busque S, Dejbakhsh-Jones S, et al. Tolerance and chimerism after renal and hematopoietic-cell transplantation. N Engl J Med 2008 358 : 362.
    • (2008) N Engl J Med , vol.358 , pp. 362
    • Scandling, J.D.1    Busque, S.2    Dejbakhsh-Jones, S.3
  • 82
    • 0032852141 scopus 로고    scopus 로고
    • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
    • Spitzer TR, Delmonico F, Tolkoff-Rubin N, et al. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation 1999 68 : 480.
    • (1999) Transplantation , vol.68 , pp. 480
    • Spitzer, T.R.1    Delmonico, F.2    Tolkoff-Rubin, N.3
  • 83
    • 0036853026 scopus 로고    scopus 로고
    • Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease
    • Buhler LH, Spitzer TR, Sykes M, et al. Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation 2002 74 : 1405.
    • (2002) Transplantation , vol.74 , pp. 1405
    • Buhler, L.H.1    Spitzer, T.R.2    Sykes, M.3
  • 84
    • 0030987616 scopus 로고    scopus 로고
    • Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys
    • Kimikawa M, Sachs DH, Colvin RB, Bartholomew A, Kawai T, Cosimi AB. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation 1997 64 : 709.
    • (1997) Transplantation , vol.64 , pp. 709
    • Kimikawa, M.1    Sachs, D.H.2    Colvin, R.B.3    Bartholomew, A.4    Kawai, T.5    Cosimi, A.B.6
  • 85
    • 38549088096 scopus 로고    scopus 로고
    • HLA-mismatched renal transplantation without maintenance immunosuppression
    • Kawai T, Cosimi AB, Spitzer TR, et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008 358 : 353.
    • (2008) N Engl J Med , vol.358 , pp. 353
    • Kawai, T.1    Cosimi, A.B.2    Spitzer, T.R.3
  • 86
    • 0034988517 scopus 로고    scopus 로고
    • Engraftment syndrome following hematopoietic stem cell transplantation
    • Spitzer TR. Engraftment syndrome following hematopoietic stem cell transplantation. Bone Marrow Transplant 2001 27 : 893.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 893
    • Spitzer, T.R.1
  • 87
    • 17844372217 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation, mixed chimerism, and tolerance in living related donor renal allograft recipients
    • Trivedi HL, Vanikar AV, Modi PR, et al. Allogeneic hematopoietic stem-cell transplantation, mixed chimerism, and tolerance in living related donor renal allograft recipients. Transplant Proc 2005 37 : 737.
    • (2005) Transplant Proc , vol.37 , pp. 737
    • Trivedi, H.L.1    Vanikar, A.V.2    Modi, P.R.3
  • 88
    • 4544223677 scopus 로고    scopus 로고
    • Donor stem cell infusion after non-myeloablative conditioning for tolerance induction to HLA mismatched adult living-donor liver graft
    • Donckier V, Troisi R, Toungouz M, et al. Donor stem cell infusion after non-myeloablative conditioning for tolerance induction to HLA mismatched adult living-donor liver graft. Transpl Immunol 2004 13 : 139.
    • (2004) Transpl Immunol , vol.13 , pp. 139
    • Donckier, V.1    Troisi, R.2    Toungouz, M.3
  • 89
    • 49149127206 scopus 로고    scopus 로고
    • Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance
    • Stapler D, Lee ED, Selvaraj SA, et al. Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance. J Immunol 2008 180 : 3190.
    • (2008) J Immunol , vol.180 , pp. 3190
    • Stapler, D.1    Lee, E.D.2    Selvaraj, S.A.3
  • 90
    • 31144479123 scopus 로고    scopus 로고
    • TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts
    • Thornley TB, Brehm MA, Markees TG, et al. TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol 2006 176 : 1561.
    • (2006) J Immunol , vol.176 , pp. 1561
    • Thornley, T.B.1    Brehm, M.A.2    Markees, T.G.3
  • 91
    • 0037097798 scopus 로고    scopus 로고
    • Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms
    • Forman D, Welsh RM, Markees TG, et al. Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms. J Immunol 2002 168 : 6047.
    • (2002) J Immunol , vol.168 , pp. 6047
    • Forman, D.1    Welsh, R.M.2    Markees, T.G.3
  • 92
    • 0024348810 scopus 로고
    • Antiviral T cell competence and restriction specificity of mixed allogeneic (P1+ P2 - - P1) irradiation chimeras
    • Rüedi E, Sykes M, Ildstad ST, et al. Antiviral T cell competence and restriction specificity of mixed allogeneic (P1+ P2 - - P1) irradiation chimeras. Cell Immunol 1989 121 : 185.
    • (1989) Cell Immunol , vol.121 , pp. 185
    • Rüedi, E.1    Sykes, M.2    Ildstad, S.T.3
  • 93
    • 34848815451 scopus 로고    scopus 로고
    • Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections
    • Koehn BH, Williams MA, Borom K, et al. Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections. J Immunol 2007 179 : 2616.
    • (2007) J Immunol , vol.179 , pp. 2616
    • Koehn, B.H.1    Williams, M.A.2    Borom, K.3
  • 94
    • 33750131777 scopus 로고    scopus 로고
    • Early immunosuppression withdrawal after living donor liver transplantation and donor stem cell infusion
    • Donckier V, Troisi R, Le Moine A, et al. Early immunosuppression withdrawal after living donor liver transplantation and donor stem cell infusion. Liver Transpl 2006 12 : 1523.
    • (2006) Liver Transpl , vol.12 , pp. 1523
    • Donckier, V.1    Troisi, R.2    Le Moine, A.3
  • 95
    • 4544288229 scopus 로고    scopus 로고
    • A strategy to achieve donor-specific hyporesponsiveness in cadaver renal allograft recipients by donor haematopoietic stem cell transplantation into the thymus and periphery
    • Trivedi HL, Vanikar AV, Vakil JM, Shah VR, Modi PR, Trivedi VB. A strategy to achieve donor-specific hyporesponsiveness in cadaver renal allograft recipients by donor haematopoietic stem cell transplantation into the thymus and periphery. Nephrol Dial Transplant 2004 19 : 2374.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2374
    • Trivedi, H.L.1    Vanikar, A.V.2    Vakil, J.M.3    Shah, V.R.4    Modi, P.R.5    Trivedi, V.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.