메뉴 건너뛰기




Volumn 40, Issue 2, 2012, Pages 131-142.e4

Role of tumor suppressor p53 in megakaryopoiesis and platelet function

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; PADGEM PROTEIN; PROTEIN P53;

EID: 84855610427     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2011.10.006     Document Type: Article
Times cited : (29)

References (65)
  • 2
    • 33846921755 scopus 로고    scopus 로고
    • The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging
    • Dumble M., Moore L., Chambers S.M., et al. The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood 2007, 109:1736-1742.
    • (2007) Blood , vol.109 , pp. 1736-1742
    • Dumble, M.1    Moore, L.2    Chambers, S.M.3
  • 3
    • 58049216794 scopus 로고    scopus 로고
    • P53 regulates hematopoietic stem cell quiescence
    • Liu Y., Elf S.E., Miyata Y., et al. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 2009, 4:37-48.
    • (2009) Cell Stem Cell , vol.4 , pp. 37-48
    • Liu, Y.1    Elf, S.E.2    Miyata, Y.3
  • 4
    • 0037711685 scopus 로고    scopus 로고
    • Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice
    • TeKippe M., Harrison D.E., Chen J. Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice. Exp Hematol 2003, 31:521-527.
    • (2003) Exp Hematol , vol.31 , pp. 521-527
    • TeKippe, M.1    Harrison, D.E.2    Chen, J.3
  • 5
    • 70349897697 scopus 로고    scopus 로고
    • The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior
    • Liu Y., Elf S.E., Asai T., et al. The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior. Cell Cycle 2009, 8:3120-3124.
    • (2009) Cell Cycle , vol.8 , pp. 3120-3124
    • Liu, Y.1    Elf, S.E.2    Asai, T.3
  • 6
    • 38349119453 scopus 로고    scopus 로고
    • A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis
    • Chen C., Fuhrken P.G., Huang L.T., et al. A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis. BMC Genomics 2007, 8:384.
    • (2007) BMC Genomics , vol.8 , pp. 384
    • Chen, C.1    Fuhrken, P.G.2    Huang, L.T.3
  • 7
    • 47049121303 scopus 로고    scopus 로고
    • Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis
    • Fuhrken P.G., Apostolidis P.A., Lindsey S., Miller W.M., Papoutsakis E.T. Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis. J Biol Chem 2008, 283:15589-15600.
    • (2008) J Biol Chem , vol.283 , pp. 15589-15600
    • Fuhrken, P.G.1    Apostolidis, P.A.2    Lindsey, S.3    Miller, W.M.4    Papoutsakis, E.T.5
  • 8
    • 43049102041 scopus 로고    scopus 로고
    • Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis
    • Fuhrken P.G., Chen C., Apostolidis P.A., Wang M., Miller W.M., Papoutsakis E.T. Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis. Physiol Genomics 2008, 33:159-169.
    • (2008) Physiol Genomics , vol.33 , pp. 159-169
    • Fuhrken, P.G.1    Chen, C.2    Apostolidis, P.A.3    Wang, M.4    Miller, W.M.5    Papoutsakis, E.T.6
  • 9
    • 33847044392 scopus 로고    scopus 로고
    • Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation
    • Fuhrken P.G., Chen C., Miller W.M., Papoutsakis E.T. Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation. Exp Hematol 2007, 35:476-489.
    • (2007) Exp Hematol , vol.35 , pp. 476-489
    • Fuhrken, P.G.1    Chen, C.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 10
    • 70349810821 scopus 로고    scopus 로고
    • Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition
    • 1340-1352, e3
    • Giammona L.M., Panuganti S., Kemper J.M., et al. Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. Exp Hematol 2009, 37. 1340-1352, e3.
    • (2009) Exp Hematol , vol.37
    • Giammona, L.M.1    Panuganti, S.2    Kemper, J.M.3
  • 11
    • 0033580225 scopus 로고    scopus 로고
    • Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e
    • Ritchie A., Braun S.E., He J., Broxmeyer H.E. Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e. Oncogene 1999, 18:1465-1477.
    • (1999) Oncogene , vol.18 , pp. 1465-1477
    • Ritchie, A.1    Braun, S.E.2    He, J.3    Broxmeyer, H.E.4
  • 12
    • 0029894091 scopus 로고    scopus 로고
    • Thrombopoietin suppresses apoptosis and behaves as a survival factor for the human growth factor-dependent cell line, M07e
    • Ritchie A., Vadhan-Raj S., Broxmeyer H.E. Thrombopoietin suppresses apoptosis and behaves as a survival factor for the human growth factor-dependent cell line, M07e. Stem Cells 1996, 14:330-336.
    • (1996) Stem Cells , vol.14 , pp. 330-336
    • Ritchie, A.1    Vadhan-Raj, S.2    Broxmeyer, H.E.3
  • 14
    • 0032523012 scopus 로고    scopus 로고
    • Role of p53 in hematopoietic recovery after cytotoxic treatment
    • Wlodarski P., Wasik M., Ratajczak M.Z., et al. Role of p53 in hematopoietic recovery after cytotoxic treatment. Blood 1998, 91:2998-3006.
    • (1998) Blood , vol.91 , pp. 2998-3006
    • Wlodarski, P.1    Wasik, M.2    Ratajczak, M.Z.3
  • 15
    • 0036987287 scopus 로고    scopus 로고
    • P53 dependency of radio-adaptive responses in endogenous spleen colonies and peripheral blood-cell counts in C57BL mice
    • Horie K., Kubo K., Yonezawa M. p53 dependency of radio-adaptive responses in endogenous spleen colonies and peripheral blood-cell counts in C57BL mice. J Radiat Res (Tokyo) 2002, 43:353-360.
    • (2002) J Radiat Res (Tokyo) , vol.43 , pp. 353-360
    • Horie, K.1    Kubo, K.2    Yonezawa, M.3
  • 16
    • 0028118111 scopus 로고
    • Tumor spectrum analysis in p53-mutant mice
    • Jacks T., Remington L., Williams B.O., et al. Tumor spectrum analysis in p53-mutant mice. Curr Biol 1994, 4:1-7.
    • (1994) Curr Biol , vol.4 , pp. 1-7
    • Jacks, T.1    Remington, L.2    Williams, B.O.3
  • 17
    • 73849128091 scopus 로고    scopus 로고
    • A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome
    • Barlow J.L., Drynan L.F., Hewett D.R., et al. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome. Nat Med 2010, 16:59-66.
    • (2010) Nat Med , vol.16 , pp. 59-66
    • Barlow, J.L.1    Drynan, L.F.2    Hewett, D.R.3
  • 18
    • 0035496922 scopus 로고    scopus 로고
    • Mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis
    • Pestina T.I., Cleveland J.L., Yang C., Zambetti G.P., Jackson C.W. Mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis. Blood 2001, 98:2084-2090.
    • (2001) Blood , vol.98 , pp. 2084-2090
    • Pestina, T.I.1    Cleveland, J.L.2    Yang, C.3    Zambetti, G.P.4    Jackson, C.W.5
  • 19
    • 77953412766 scopus 로고    scopus 로고
    • Gender dependence for a subset of the low-abundance signaling proteome in human platelets
    • Eidelman O., Jozwik C., Huang W., et al. Gender dependence for a subset of the low-abundance signaling proteome in human platelets. Hum Genomics Proteomics 2010, 2010:164906.
    • (2010) Hum Genomics Proteomics , vol.2010 , pp. 164906
    • Eidelman, O.1    Jozwik, C.2    Huang, W.3
  • 20
    • 33748189345 scopus 로고    scopus 로고
    • Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3
    • Larson M.K., Watson S.P. Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3. Blood 2006, 108:1509-1514.
    • (2006) Blood , vol.108 , pp. 1509-1514
    • Larson, M.K.1    Watson, S.P.2
  • 21
    • 0030942587 scopus 로고    scopus 로고
    • A single injection of pegylated murine megakaryocyte growth and development factor (MGDF) into mice is sufficient to produce a profound stimulation of megakaryocyte frequency, size, and ploidization
    • Arnold J.T., Daw N.C., Stenberg P.E., Jayawardene D., Srivastava D.K., Jackson C.W. A single injection of pegylated murine megakaryocyte growth and development factor (MGDF) into mice is sufficient to produce a profound stimulation of megakaryocyte frequency, size, and ploidization. Blood 1997, 89:823-833.
    • (1997) Blood , vol.89 , pp. 823-833
    • Arnold, J.T.1    Daw, N.C.2    Stenberg, P.E.3    Jayawardene, D.4    Srivastava, D.K.5    Jackson, C.W.6
  • 22
    • 38349102225 scopus 로고    scopus 로고
    • Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout
    • Hitchcock I.S., Fox N.E., Prevost N., Sear K., Shattil S.J., Kaushansky K. Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout. Blood 2008, 111:596-604.
    • (2008) Blood , vol.111 , pp. 596-604
    • Hitchcock, I.S.1    Fox, N.E.2    Prevost, N.3    Sear, K.4    Shattil, S.J.5    Kaushansky, K.6
  • 23
    • 78851470497 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization
    • Lindsey S., Papoutsakis E.T. The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization. Br J Haematol 2011, 152:469-484.
    • (2011) Br J Haematol , vol.152 , pp. 469-484
    • Lindsey, S.1    Papoutsakis, E.T.2
  • 24
    • 79251576222 scopus 로고    scopus 로고
    • Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells
    • Kostyak J.C., Naik U.P. Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells. PLoS One 2011, 6:e14513.
    • (2011) PLoS One , vol.6
    • Kostyak, J.C.1    Naik, U.P.2
  • 25
    • 33750061906 scopus 로고    scopus 로고
    • Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes
    • Giammona L.M., Fuhrken P.G., Papoutsakis E.T., Miller W.M. Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes. Br J Haematol 2006, 135:554-566.
    • (2006) Br J Haematol , vol.135 , pp. 554-566
    • Giammona, L.M.1    Fuhrken, P.G.2    Papoutsakis, E.T.3    Miller, W.M.4
  • 26
    • 43249121384 scopus 로고    scopus 로고
    • P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1
    • Gilles L., Guieze R., Bluteau D., et al. P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1. Blood 2008, 111:4081-4091.
    • (2008) Blood , vol.111 , pp. 4081-4091
    • Gilles, L.1    Guieze, R.2    Bluteau, D.3
  • 27
    • 58149388333 scopus 로고    scopus 로고
    • A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion
    • Tucker K.L., Sage T., Stevens J.M., et al. A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion. Blood 2008, 112:4523-4531.
    • (2008) Blood , vol.112 , pp. 4523-4531
    • Tucker, K.L.1    Sage, T.2    Stevens, J.M.3
  • 28
    • 22244469478 scopus 로고    scopus 로고
    • Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets
    • Prevost N., Woulfe D.S., Jiang H., et al. Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. Proc Natl Acad Sci U S A 2005, 102:9820-9825.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9820-9825
    • Prevost, N.1    Woulfe, D.S.2    Jiang, H.3
  • 29
    • 0037093203 scopus 로고    scopus 로고
    • Fibronectin- and protein kinase C-mediated activation of ERK/MAPK are essential for proplateletlike formation
    • Jiang F., Jia Y., Cohen I. Fibronectin- and protein kinase C-mediated activation of ERK/MAPK are essential for proplateletlike formation. Blood 2002, 99:3579-3584.
    • (2002) Blood , vol.99 , pp. 3579-3584
    • Jiang, F.1    Jia, Y.2    Cohen, I.3
  • 30
    • 0037417895 scopus 로고    scopus 로고
    • A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis
    • Yang H., Haddad H., Tomas C., Alsaker K., Papoutsakis E.T. A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis. Proc Natl Acad Sci U S A 2003, 100:1122-1127.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1122-1127
    • Yang, H.1    Haddad, H.2    Tomas, C.3    Alsaker, K.4    Papoutsakis, E.T.5
  • 31
    • 51049113603 scopus 로고    scopus 로고
    • Notch signaling specifies megakaryocyte development from hematopoietic stem cells
    • Mercher T., Cornejo M.G., Sears C., et al. Notch signaling specifies megakaryocyte development from hematopoietic stem cells. Cell Stem Cell 2008, 3:314-326.
    • (2008) Cell Stem Cell , vol.3 , pp. 314-326
    • Mercher, T.1    Cornejo, M.G.2    Sears, C.3
  • 33
    • 33846921020 scopus 로고    scopus 로고
    • Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2
    • Chen Z., Hu M., Shivdasani R.A. Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2. Blood 2007, 109:1451-1459.
    • (2007) Blood , vol.109 , pp. 1451-1459
    • Chen, Z.1    Hu, M.2    Shivdasani, R.A.3
  • 34
    • 0037311919 scopus 로고    scopus 로고
    • TM4: a free, open-source system for microarray data management and analysis
    • Saeed A.I., Sharov V., White J., et al. TM4: a free, open-source system for microarray data management and analysis. Biotechniques 2003, 34:374-378.
    • (2003) Biotechniques , vol.34 , pp. 374-378
    • Saeed, A.I.1    Sharov, V.2    White, J.3
  • 35
    • 34250006259 scopus 로고    scopus 로고
    • Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization
    • Muntean A.G., Pang L., Poncz M., Dowdy S.F., Blobel G.A., Crispino J.D. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood 2007, 109:5199-5207.
    • (2007) Blood , vol.109 , pp. 5199-5207
    • Muntean, A.G.1    Pang, L.2    Poncz, M.3    Dowdy, S.F.4    Blobel, G.A.5    Crispino, J.D.6
  • 36
    • 34147162377 scopus 로고    scopus 로고
    • A guide to murine platelet structure, function, assays, and genetic alterations
    • Jirouskova M., Shet A.S., Johnson G.J. A guide to murine platelet structure, function, assays, and genetic alterations. J Thromb Haemost 2007, 5:661-669.
    • (2007) J Thromb Haemost , vol.5 , pp. 661-669
    • Jirouskova, M.1    Shet, A.S.2    Johnson, G.J.3
  • 37
    • 21644440111 scopus 로고    scopus 로고
    • Flow-cytometric analysis of mouse platelet function
    • Nieswandt B., Schulte V., Bergmeier W. Flow-cytometric analysis of mouse platelet function. Methods Mol Biol 2004, 272:255-268.
    • (2004) Methods Mol Biol , vol.272 , pp. 255-268
    • Nieswandt, B.1    Schulte, V.2    Bergmeier, W.3
  • 38
    • 21644481801 scopus 로고    scopus 로고
    • Flow-cytometric analysis of platelet-membrane glycoprotein expression and platelet activation
    • Goodall A.H., Appleby J. Flow-cytometric analysis of platelet-membrane glycoprotein expression and platelet activation. Methods Mol Biol 2004, 272:225-253.
    • (2004) Methods Mol Biol , vol.272 , pp. 225-253
    • Goodall, A.H.1    Appleby, J.2
  • 39
    • 0032698162 scopus 로고    scopus 로고
    • Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways
    • Shattil S.J. Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways. Thromb Haemost 1999, 82:318-325.
    • (1999) Thromb Haemost , vol.82 , pp. 318-325
    • Shattil, S.J.1
  • 40
    • 61749097572 scopus 로고    scopus 로고
    • PKCalpha regulates platelet granule secretion and thrombus formation in mice
    • Konopatskaya O., Gilio K., Harper M.T., et al. PKCalpha regulates platelet granule secretion and thrombus formation in mice. J Clin Invest 2009, 119:399-407.
    • (2009) J Clin Invest , vol.119 , pp. 399-407
    • Konopatskaya, O.1    Gilio, K.2    Harper, M.T.3
  • 41
    • 0035760897 scopus 로고    scopus 로고
    • Role of p21(Cip1/Waf1) in cell-cycle exit of endomitotic megakaryocytes
    • Baccini V., Roy L., Vitrat N., et al. Role of p21(Cip1/Waf1) in cell-cycle exit of endomitotic megakaryocytes. Blood 2001, 98:3274-3282.
    • (2001) Blood , vol.98 , pp. 3274-3282
    • Baccini, V.1    Roy, L.2    Vitrat, N.3
  • 42
    • 0028957238 scopus 로고
    • Invitro p53 and/or Rb antisense oligonucleotide treatment in association with growth factors induces the proliferation of peripheral hematopoietic progenitors
    • Mahdi T., Brizard A., Millet C., Dore P., Tanzer J., Kitzis A. Invitro p53 and/or Rb antisense oligonucleotide treatment in association with growth factors induces the proliferation of peripheral hematopoietic progenitors. J Cell Sci 1995, 108(Pt 3):1287-1293.
    • (1995) J Cell Sci , vol.108 , Issue.PART 3 , pp. 1287-1293
    • Mahdi, T.1    Brizard, A.2    Millet, C.3    Dore, P.4    Tanzer, J.5    Kitzis, A.6
  • 43
    • 0033957407 scopus 로고    scopus 로고
    • Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin invivo
    • Luoh S.M., Stefanich E., Solar G., et al. Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin invivo. Mol Cell Biol 2000, 20:507-515.
    • (2000) Mol Cell Biol , vol.20 , pp. 507-515
    • Luoh, S.M.1    Stefanich, E.2    Solar, G.3
  • 44
    • 75649135006 scopus 로고    scopus 로고
    • Differences between newborn and adult mice in their response to immune thrombocytopenia
    • Hu Z., Slayton W.B., Rimsza L.M., Bailey M., Sallmon H., Sola-Visner M.C. Differences between newborn and adult mice in their response to immune thrombocytopenia. Neonatology 2010, 98:100-108.
    • (2010) Neonatology , vol.98 , pp. 100-108
    • Hu, Z.1    Slayton, W.B.2    Rimsza, L.M.3    Bailey, M.4    Sallmon, H.5    Sola-Visner, M.C.6
  • 45
    • 67651028102 scopus 로고    scopus 로고
    • Survivin is not required for the endomitotic cell cycle of megakaryocytes
    • Wen Q., Leung C., Huang Z., et al. Survivin is not required for the endomitotic cell cycle of megakaryocytes. Blood 2009, 114:153-156.
    • (2009) Blood , vol.114 , pp. 153-156
    • Wen, Q.1    Leung, C.2    Huang, Z.3
  • 46
    • 43249101683 scopus 로고    scopus 로고
    • Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice
    • McCrann D.J., Yezefski T., Nguyen H.G., et al. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice. Blood 2008, 111:4092-4095.
    • (2008) Blood , vol.111 , pp. 4092-4095
    • McCrann, D.J.1    Yezefski, T.2    Nguyen, H.G.3
  • 47
    • 0033557572 scopus 로고    scopus 로고
    • P21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells
    • Mantel C., Braun S.E., Reid S., et al. p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells. Blood 1999, 93:1390-1398.
    • (1999) Blood , vol.93 , pp. 1390-1398
    • Mantel, C.1    Braun, S.E.2    Reid, S.3
  • 49
    • 6344221309 scopus 로고    scopus 로고
    • Cell division and cell survival in the absence of survivin
    • Yang D., Welm A., Bishop J.M. Cell division and cell survival in the absence of survivin. Proc Natl Acad Sci U S A 2004, 101:15100-15105.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15100-15105
    • Yang, D.1    Welm, A.2    Bishop, J.M.3
  • 50
    • 0345826036 scopus 로고    scopus 로고
    • Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis
    • Beltrami E., Plescia J., Wilkinson J.C., Duckett C.S., Altieri D.C. Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis. J Biol Chem 2004, 279:2077-2084.
    • (2004) J Biol Chem , vol.279 , pp. 2077-2084
    • Beltrami, E.1    Plescia, J.2    Wilkinson, J.C.3    Duckett, C.S.4    Altieri, D.C.5
  • 51
    • 77957702911 scopus 로고    scopus 로고
    • Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process
    • Epub 2010 Jun 14
    • Lordier L., Chang Y., Jalil A., et al. Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process. Blood 2010, 116:2345-2355. Epub 2010 Jun 14.
    • (2010) Blood , vol.116 , pp. 2345-2355
    • Lordier, L.1    Chang, Y.2    Jalil, A.3
  • 52
    • 77956290439 scopus 로고    scopus 로고
    • The c-Myc target Glycoprotein1balpha links cytokinesis failure to oncogenic signal transduction pathways in cultured human cells
    • Wu Q., Xu F.L., Li Y., Prochownik E.V., Saunders W.S. The c-Myc target Glycoprotein1balpha links cytokinesis failure to oncogenic signal transduction pathways in cultured human cells. PLoS One 2010, 5:e10819.
    • (2010) PLoS One , vol.5
    • Wu, Q.1    Xu, F.L.2    Li, Y.3    Prochownik, E.V.4    Saunders, W.S.5
  • 53
    • 62549148270 scopus 로고    scopus 로고
    • P53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M., Zhu S., Wu F., et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A 2009, 106:3207-3212.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 54
    • 70349246859 scopus 로고    scopus 로고
    • C-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors
    • Guo Y., Niu C., Breslin P., et al. c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Blood 2009, 114:2097-2106.
    • (2009) Blood , vol.114 , pp. 2097-2106
    • Guo, Y.1    Niu, C.2    Breslin, P.3
  • 55
    • 61849152839 scopus 로고    scopus 로고
    • Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes
    • Tiedt R., Coers J., Ziegler S., et al. Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. Blood 2009, 113:1768-1777.
    • (2009) Blood , vol.113 , pp. 1768-1777
    • Tiedt, R.1    Coers, J.2    Ziegler, S.3
  • 56
    • 77955895723 scopus 로고    scopus 로고
    • Role of the p53 family in stabilizing the genome and preventing polyploidization
    • Talos F., Moll U.M. Role of the p53 family in stabilizing the genome and preventing polyploidization. Adv Exp Med Biol 2010, 676:73-91.
    • (2010) Adv Exp Med Biol , vol.676 , pp. 73-91
    • Talos, F.1    Moll, U.M.2
  • 58
    • 79151476371 scopus 로고    scopus 로고
    • The clock gene Per2 is required for normal platelet formation and function
    • Zhao Y., Zhang Y., Wang S., Hua Z., Zhang J. The clock gene Per2 is required for normal platelet formation and function. Thromb Res 2011, 127:122-130.
    • (2011) Thromb Res , vol.127 , pp. 122-130
    • Zhao, Y.1    Zhang, Y.2    Wang, S.3    Hua, Z.4    Zhang, J.5
  • 59
    • 36148955807 scopus 로고    scopus 로고
    • Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion
    • Leon C., Eckly A., Hechler B., et al. Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. Blood 2007, 110:3183-3191.
    • (2007) Blood , vol.110 , pp. 3183-3191
    • Leon, C.1    Eckly, A.2    Hechler, B.3
  • 60
    • 0001027292 scopus 로고    scopus 로고
    • Gelsolin, a multifunctional actin regulatory protein
    • Sun H.Q., Yamamoto M., Mejillano M., Yin H.L. Gelsolin, a multifunctional actin regulatory protein. J Biol Chem 1999, 274:33179-33182.
    • (1999) J Biol Chem , vol.274 , pp. 33179-33182
    • Sun, H.Q.1    Yamamoto, M.2    Mejillano, M.3    Yin, H.L.4
  • 61
    • 0028914814 scopus 로고
    • Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin
    • Witke W., Sharpe A.H., Hartwig J.H., Azuma T., Stossel T.P., Kwiatkowski D.J. Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell 1995, 81:41-51.
    • (1995) Cell , vol.81 , pp. 41-51
    • Witke, W.1    Sharpe, A.H.2    Hartwig, J.H.3    Azuma, T.4    Stossel, T.P.5    Kwiatkowski, D.J.6
  • 63
    • 79961006027 scopus 로고    scopus 로고
    • Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes
    • Shin J.W., Swift J., Spinler K.R., Discher D.E. Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes. Proc Natl Acad Sci US A 2011, 127:122-130.
    • (2011) Proc Natl Acad Sci US A , vol.127 , pp. 122-130
    • Shin, J.W.1    Swift, J.2    Spinler, K.R.3    Discher, D.E.4
  • 64
    • 0035901615 scopus 로고    scopus 로고
    • A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets
    • Schwer H.D., Lecine P., Tiwari S., Italiano J.E., Hartwig J.H., Shivdasani R.A. A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets. Curr Biol 2001, 11:579-586.
    • (2001) Curr Biol , vol.11 , pp. 579-586
    • Schwer, H.D.1    Lecine, P.2    Tiwari, S.3    Italiano, J.E.4    Hartwig, J.H.5    Shivdasani, R.A.6
  • 65
    • 28844485066 scopus 로고    scopus 로고
    • Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes
    • Patel S.R., Richardson J.L., Schulze H., et al. Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood 2005, 106:4076-4085.
    • (2005) Blood , vol.106 , pp. 4076-4085
    • Patel, S.R.1    Richardson, J.L.2    Schulze, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.