Host susceptibility to Brucella abortus infection is more pronounced in IFN-γ knockout than IL-12/β2-microglobulin double-deficient mice

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Brandão, Ana Paula M S ^a   Oliveira, Fernanda S ^a   Carvalho, Natalia B ^a   Vieira, Leda Q ^a   Azevedo, Vasco ^a   MacEdo, Gilson C ^b   Oliveira, Sergio C ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; GAMMA INTERFERON; INTERLEUKIN 12; ALPHA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; BRUCELLA ABORTUS; BRUCELLOSIS; CD8+ T LYMPHOCYTE; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOTOXICITY; DISEASE PREDISPOSITION; HOST SUSCEPTIBILITY; IMMUNE RESPONSE; KNOCKOUT MOUSE; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; MICROBIOLOGY; MOUSE MUTANT;

ANIMALS; BETA 2-MICROGLOBULIN; BRUCELLA ABORTUS; BRUCELLOSIS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERFERON-ALPHA; INTERFERON-GAMMA; INTERLEUKIN-12; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLEEN;

EID: 84855583666     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/589494     Document Type: Article

References (31)

1. Corbel M. J., Brucellosis: an overview Emerging Infectious Diseases 1997 3 2 213 221 (Pubitemid 127431682)
2. Detilleux P. G., Deyoe B. L., Cheville N. F., Penetration and intracellular growth of Brucella abortus in nonphagocytic cells in vitro Infection and Immunity 1990 58 7 2320 2328 (Pubitemid 20212314)
3. Jones S. M., Winter A. J., Survival of virulent and attenuated strains of Brucella abortus in normal and gamma interferon-activated murine peritoneal macrophages Infection and Immunity 1992 60 7 3011 3014
4. Archambaud C., Salcedo S. P., Lelouard H., Devilard E., De Bovis B., Van Rooijen N., Gorvel J. P., Malissen B., Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection European Journal of Immunology 2010 40 12 3458 3471
5. Golding B., Scott D. E., Scharf O., Huang L. Y., Zaitseva M., Lapham C., Eller N., Golding H., Immunity and protection against Brucella abortus Microbes and Infection 2001 3 1 43 48 (Pubitemid 32172039)
6. Oliveira S. C., Harms J. S., Rech E. L., Rodarte R. S., Bocca A. L., Goes A. M., Splitter G. A., The role of T cell subsets and cytokines in the regulation of intracellular bacterial infection Brazilian Journal of Medical and Biological Research 1998 31 1 77 84 (Pubitemid 128524614)
7. Oliveira S. C., Splitter G. A., CD8+ type 1 CD44(hl) CD45 RB(lo)T lymphocytes control intracellular Brucella abortus infection as demonstrated in major histocompatibility complex class I- and class II-deficient mice European Journal of Immunology 1995 25 9 2551 2557
8. Murphy E. A., Sathiyaseelan J., Parent M. A., Zou B., Baldwin C. L., Interferon- is crucial for surviving a Brucella abortus infection in both resistant C57BL/6 and susceptible BALB/c mice Immunology 2001 103 4 511 518 (Pubitemid 32744399)
9. Sathiyaseelan J., Goenka R., Parent M., Benson R. M., Murphy E. A., Fernandes D. M., Foulkes A. S., Baldwin C. L., Treatment of Brucella -susceptible mice with IL-12 increases primary and secondary immunity Cellular Immunology 2006 243 1 1 9 (Pubitemid 46275613)
10. Zhan Y., Cheers C., Endogenous gamma interferon mediates resistance to Brucella abortus infection Infection and Immunity 1993 61 11 4899 4901 (Pubitemid 23320553)
11. Fernandes D. M., Baldwin C. L., Interleukin-10 downregulates protective immunity to Brucella abortus Infection and Immunity 1995 63 3 1130 1133
12. Fernandes D. M., Jiang X., Jung J. H., Baldwin C. L., Comparison of T cell cytokines in resistant and susceptible mice infected with virulent Brucella abortus strain 2308 FEMS Immunology and Medical Microbiology 1996 16 3-4 193 203 (Pubitemid 27041955)
13. Zhan Y., Kelso A., Cheers C., Differential activation of Brucella -reactive CD4+ T cells by Brucella infection or immunization with antigenic extracts Infection and Immunity 1995 63 3 969 975
14. Pavlov H., Hogarth M., McKenzie F. C., Cheers C., In vivo and in vitro effects of monoclonal antibody to Ly antigens on immunity to infection Cellular Immunology 1982 71 1 127 138 (Pubitemid 12032752)
15. Araya L. N., Elzer P. H., Rowe G. E., Enright F. M., Winter A. J., Temporal development of protective cell-mediated and humoral immunity in BALB/c mice infected with Brucella abortus Journal of Immunology 1989 143 10 3330 3337 (Pubitemid 20010164)
16. Zhan Y., Cheers C., Endogenous interleukin-12 is involved in resistance to Brucella abortus infection Infection and Immunity 1995 63 4 1387 1390
17. Trant C. G. M. C., Lacerda T. L. S., Carvalho N. B., Azevedo V., Rosinha G. M. S., Salcedo S. P., Gorvel J. P., Oliveira S. C., The Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces protection superior to that of vaccine strain 19 in immunocompromised and immunocompetent mice Infection and Immunity 2010 78 5 2283 2291
18. Macedo G. C., Magnani D. M., Carvalho N. B., Bruna-Romero O., Gazzinelli R. T., Oliveira S. C., Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection Journal of Immunology 2008 180 2 1080 1087
19. Lacerda T. L. S., Cardoso P. G., Augusto de Almeida L., Camargo I. L. B. D. C., Afonso D. A. F., Trant C. C., Macedo G. C., Campos E., Cravero S. L., Salcedo S. P., Gorvel J. P., Oliveira S. C., Inactivation of formyltransferase (wbkC) gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice Vaccine 2010 28 34 5627 5634
20. Coffman R. L., Origins of the TH1-TH2 model: a personal perspective Nature Immunology 2006 7 6 539 541 (Pubitemid 43797329)
21. Oliveira S. C., de Almeida L. A., Carvalho N. B., Oliveira F. S., Lacerda T. L. S., Update on the role of innate immune receptors during Brucella abortus infection. Veterinary Immunology and Immunopathology. In press
22. Zinkernagel R. M., Restriction by H 2 gene complex of transfer of cell mediated immunity to Listeria monocytogenes Nature 1974 251 5472 230 233
23. Ko J., Gendron-Fitzpatrick A., Splitter G. A., Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to Brucellosis Journal of Immunology 2002 168 5 2433 2440 (Pubitemid 34171847)
24. Norman M. U., Zbytnuik L., Kubes P., Interferon- limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism European Journal of Immunology 2008 38 5 1368 1380
25. Yagi R., Junttila I. S., Wei G., Urban J. F., Zhao K., Paul W. E., Zhu J., The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon- Immunity 2010 32 4 507 517
26. Brombacher F., Dorfmller A., Magram J., Dai W. J., Khler G., Wunderlin A., Palmer-Lehmann K., Gately M. K., Alber G., IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes International Immunology 1999 11 3 325 332 (Pubitemid 29121619)
27. Freudenberg M. A., Merlin T., Kalis C., Chvatchko Y., Stbig H., Galanos C., Cutting edge: a murine, IL-12-independent pathway of IFN-γ induction by gram-negative bacteria based on STAT4 activation by type I IFN and IL-18 signaling Journal of Immunology 2002 169 4 1665 1668 (Pubitemid 34857622)
28. Paranavitana C., Zelazowska E., Izadjoo M., Hoover D., Interferon- associated cytokines and chemokines produced by spleen cells from Brucella -immune mice Cytokine 2005 30 2 86 92 (Pubitemid 40432634)
29. de Almeida L. A., Carvalho N. B., Oliveira F. S., Lacerda T. L.S., Vasconcelos A. C., Nogueira L., Bafica A., Silva A. M., Oliveira S. C., MyD88 and STING signaling pathways are required for IRF3-mediated IFN-γ induction in response to Brucella abortus infection PLoS ONE 2011 6 8
30. Oliveira S. C., de Oliveira F. S., Macedo G. C., de Almeida L. A., Carvalho N. B., The role of innate immune receptors in the control of Brucella abortus infection: toll-like receptors and beyond Microbes and Infection 2008 10 9 1005 1009
31. Durward M. A., Harms J., Magnani D. M., Eskra L., Splitter G. A., Discordant Brucella melitensis antigens yield cognate CD8 T cells in vivo Infection and Immunity 2010 78 1 168 176