Comparison of T cell cytokines in resistant and susceptible mice infected with virulent Brucella abortus strain 2308

FEMS Immunology and Medical Microbiology

Volumn 16, Issue 3-4, 1996, Pages 193-203

  Fernandes, Dancella M ^a,b   Jiang, Xiaosui ^a,c   Jung, Jae Ho ^a,d   Baldwin, Cynthia L ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Brucella; interleukin 10; interleukin 4; type 1 CD4+ T cells

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BRUCELLA ABORTUS; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; BRUCELLA ABORTUS; BRUCELLOSIS; CYTOKINES; DISEASE SUSCEPTIBILITY; FEMALE; IMMUNITY, NATURAL; INTERFERON TYPE II; INTERLEUKIN-10; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SPECIES SPECIFICITY; SPLEEN; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0030608475     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(96)00083-1     Document Type: Article

References (21)

1. [1] Baldwin, C.L. and Winter, A.J. (1993) Macrophages and Brucella. In: Macrophage Pathogen Interactions (Zwilling, B. and Eisenstein, T., Eds.), pp. 363. Marcel Dekker, New York.
2. [2] Ho, M. and Cheers, C. (1982) Resistance and susceptibility of mice to bacterial infection. IV. Genetic and cellular basis of resistance to chronic infection with Brucella abortus. J. Infect. Dis. 146, 381.
3. [3] Montaraz, J.A. and Winter, A.J. (1986) Comparison of living and non living vaccines for Brucella abortus in BALB/c mice. Infect. Immun. 53, 245.
4. [4] Winter, A.J., Duncan, J.R., Santisteban, C.G., Douglas, J.T. and Adams, L.G. (1989) Capacity of passively transferred antibody to prevent establishment of Brucella abortus infection in mice. Infect. Immun. 57, 3438.
5. [5] Araya, L.N. and Winter, A.J. (1990) Comparative protection of mice against virulent and attenuated strains of Brucella abortus by passive transfer of immune T cells or serum. Infect. Immun. 58, 254.
6. [6] Araya, L.N., Elzer, P.M., Rowe, G.E., Enright, F.M. and Winter, A.J. (1989) Temporal development of protective cell mediated and humoral immunity in BALB/c mice, J. Immunol. 143, 3330.
7. [7] Pavlov, H., Hogarth, M., Mckenzie, I.F.C. and Cheers, C. (1982) In vivo and in vitro effects of monoclonal antibody to Ly antigens in immunity to infection. Cell. Immunol, 71, 127.
8. [8] Mielke, M.E.A. (1991) T cell subsets in granulatomous inflammation and immunity to Listeria monocytogenes and Brucella abortus. Behring Inst. Mitt. 88, 99.
9. [9] Jiang, X. and Baldwin, C.L. (1993) Effects of cytokines on the intracellular growth of Brucella abortus. Infect. Immun. 61, 124.
10. [10] Stevens, M.G., Pugh, G.W. and Tabatabai, L.B. (1992) Effects of IFN-γ and indomethacin in preventing Brucella abortus infection in mice. Infect. Immun. 60, 4407.
11. [11] Fernandes, D.M. and Baldwin, C.L. (1995) IL-10 downregulates protective immunity to Brucella abortus. Infect. Immun. 63, 1130.
12. [12] Khan, Y. and Cheers, C. (1993) Endogenous gamma-interferon mediates resistance to Brucella abortus infection. Infect. Immun. 61, 4899.
13. [13] Fernandes, D.M., Benson, R. and Baldwin, C.L. (1995) Lack of a role for natural killer cells in early control of Brucella abortus. Infect. Immun. 63, 4029.
14. + T cell subsets in the regulation of parasite immunity and disease. Immunol. Rev. 112, 161.
15. [15] Kaye, P.M., Curry, A.J. and Blackwell, J.M. (1991) Differential production of Th1 and Th2 derived cytokines does not determine the genetically controlled or vaccine induced rate of cure in murine visceral leishmaniasis. J. Immunol. 146, 2763.
16. [16] Andrew, S.M. and Titus, J.A. (1992) Purification of immunoglobulin G. In: Current Protocols in Immunology (Colligan, J.E. et al., Eds.), p. 2.7. John Wiley and Sons, New York.
17. [17] Dunn, P.L. and North, R.L. (1991) Early gamma interferon production by natural killer cells is important in defense against murine listeriosis. Infect. Immun. 59, 2892.
18. [18] Mossman, T.R. and Fong, T.A.T. (1989) Specific assays for cytokine production by T cells. J. Immunol. Methods 116, 151.
19. + T cells express Th1-like cytokine mRNA and proteins following in vitro stimulation with heat-inactivated Brucella abortus. Infect. Immun. 63, 2720.
20. [20] Tyring, S.K. and Lefkowitz, S.S. (1980) Strain differences in production of murine interferons. Proc. Soc. Exp. Biol. Med. 164, 519.
21. + T cells. Int. Immunol. 5, 877.