The Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces protection superior to that of vaccine strain 19 in immunocompromised and immunocompetent mice

Infection and Immunity

Volumn 78, Issue 5, 2010, Pages 2283-2291

  Trant, Cyntia G M C ^a   Lacerda, Thais L S ^a   Carvalho, Natalia B ^a   Azevedo, Vasco ^a   Rosinha, Gracia M S ^b   Salcedo, Suzana P ^c,d,e   Gorvel, Jean Pierre ^c,d,e   Oliveira, Sergio C ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b EMBRAPA CERRADOS   (Brazil)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d INSERM   (France)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BRUCELLA VACCINE; INTERFERON REGULATORY FACTOR 1; LIVE VACCINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PHOSPHOGLYCERATE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BAGG ALBINO MOUSE; BONE MARROW; BRUCELLA ABORTUS; BRUCELLOSIS; CELL VACUOLE; CONTROLLED STUDY; DELETION MUTANT; ENDOPLASMIC RETICULUM; ENDOSOME; FEMALE; GENE DELETION; GENE IDENTIFICATION; HOMOLOGOUS RECOMBINATION; IMMUNE DEFICIENCY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SOUTHERN BLOTTING; WESTERN BLOTTING; WILD TYPE;

EID: 77951251674     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01433-09     Document Type: Article

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