Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A1 receptors: Insights using knockout mice

Neuroscience Letters

Volumn 473, Issue 3, 2010, Pages 178-181

  Sawynok, Jana ^a   Reid, Allison R ^a   Fredholm, Bertil B ^b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adenosine A1 receptors; Antinociception; Caffeine; Oxcarbazepine

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; CAFFEINE; FORMALDEHYDE; OXCARBAZEPINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EVOKED RESPONSE; FEMALE; HETEROZYGOTE; HOMOZYGOTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; WILD TYPE;

ANALGESICS; ANIMALS; CAFFEINE; CARBAMAZEPINE; DRUG ANTAGONISM; FEMALE; MALE; MICE; MICE, KNOCKOUT; PAIN; PAIN MEASUREMENT; RECEPTOR, ADENOSINE A1;

EID: 77950339237     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.02.028     Document Type: Article

References (31)

1. Abo Saleem O., Hayallah A.M., Bilkei-Gorzo A., Filipek B., Zimmer A., Muller C.E. Antinociceptive effects of novel A2B adenosine receptor antagonists. J. Pharmacol. Exp. Ther. 2004, 308:358-366.
2. Ambrósio A.F., Soares-da-Silva P., Carvalho M., Carvalho A.P. Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA-093 and BIA 2-024. Neurochem. Res. 2002, 27:121-130.
3. Bianchi M., Rossini G., Sacerdote P., Panerai A.E., Berti F. Carbamazepine exerts anti-inflammatory effects in the rat. Eur. J. Pharmacol. 1995, 294:71-74.
4. Fredholm B.B., Bättig K., Holmén J., Nehlig A., Zvartau E.E. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol. Rev. 1999, 51:83-133.
5. Fredholm B.B., Chen J.-F., Masino S.A., Vaugeois J.-M. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annu. Rev. Pharmacol. Toxicol. 2005, 45:385-412.
6. 2) receptors. Psychopharmacology 1986, 90:332-335.
7. 1-adenosine receptors. Neurosci. Lett. 1988, 91:189-193.
8. Gaumond I., Arsenault P., Marchand S. Specificity of female and male sex hormones on excitatory and inhibitor phases of formalin-induced nociceptive responses. Brain Res. 2005, 1052:105-111.
9. 1 receptor. Proc. Natl. Acad. Sci. U.S.A. 2001, 16:9407-9412.
10. Kiguchi S., Ichikawa K., Kojima M. Suppressive effects of oxcarbazepine on tooth pulp-evoked potentials recorded at the trigeminal spinal tract nucleus in cats. Clin. Exp. Pharmacol. Physiol. 2001, 28:169-175.
11. Kiguchi S., Imamura T., Ichikawa K., Kojima M. Oxcarbazepine antinociception in animals with inflammatory pain or painful diabetic neuropathy. Clin. Exp. Pharmacol. Physiol. 2004, 31:57-64.
12. Mashimoto S., Ushijima I., Suetsugi M., Akimoto T., Watanabe K., Yamada M. Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats. Prog. Neuro-Psychopharmacol. Biol. Psychiat. 1998, 22:159-168.
13. Nasreddine W., Beydoun A. Oxcarbazepine in neuropathic pain. Expert Opin. Invest. Drugs 2007, 16:1615-1625.
14. Okada M., Kiryu K., Kawata Y., Mizuno K., Wada K., Tasaki H., Kaneko S. Determination of the effects of caffeine and carbamazepine on striatal dopamine release by in vivo microdialysis. Eur. J. Pharmacol. 1997, 321:181-188.
15. Sawynok J. Adenosine receptor activation and nociception. Eur. J. Pharmacol. 1998, 347:1-11.
16. J. Sawynok, Methylxanthines and pain, in: B.B. Fredholm (Ed.), Methylxanthines. Handbook of Experimental Pharmacology, Springer-Verlag, Berlin, in press.
17. Sawynok J., Liu X.J. Adenosine in the spinal cord and periphery, release and regulation of pain. Prog. Neurobiol. 2003, 69:313-340.
18. 1 receptors. Neurosci. Lett. 2008, 440:181-184.
19. Shannon H.E., Eberle E.L., Peters S.C. Comparison of the effects of anticonvulsant drugs with diverse mechanisms of action in the formalin test in rats. Neuropharmacology 2005, 48:1012-1020.
20. Skerritt J.H., Davies L.P., Johnston G.A. A purinergic component in the anticonvulsant action of carbamazepine?. Eur. J. Pharmacol. 1982, 82:195-197.
21. Skerritt J.H., Davies L.P., Johnston G.A. Interactions of the anticonvulsant carbamazepine with adenosine receptors. 1. Neurochemical studies. Epilepsia 1983, 24:634-642.
22. Stepanović-Petrović R., Tomić M., Vućkovic S., Kocev N., Ugrešić N.D., Prostran M.S., Bošković B. GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia. Pharmacology 2008, 82:53-58.
23. Tomić M.A., Vučović S.M., Stepanović-Petrović R.M., Ugrešić N., Prostran M.S., Bošković B. The anti-hyperalgesic effects of carbamazepine and oxcarbazepine are attenuated by treatment with adenosine receptor antagonists. Pain 2004, 111:253-260.
24. 1 receptors. Pharmazie 2006, 61:566-568.
25. Van Calker D., Steber R., Klotz K.N., Greil W. Carbamazepine distinguishes between adenosine receptors that mediate different second messenger responses. J. Pharmacol. 1991, 206:285-290.
26. Vućkovic S., Tomić M., Stepanović-Petrović R., Ugrešić N., Prostran M., Bošković B. Peripheral antinociception by carbamazepine in an inflammatory hyperalgesia model in the rat: a new target for carbamazepine?. J. Pharmacol. Sci. 2006, 100:310-314.
27. Vućkovic S., Tomić M., Stepanović-Petrović R., Ugrešić N., Prostran M., Bošković B. The effects of α2-adrenoceptor agents on anti-hyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory pain. Pain 2006, 125:10-19.
28. 3H]cyclohexyladenosine binding by carbamazepine. Epilepsia 1990, 31:503-512.
29. 1 receptor. Pain 2005, 113:395-404.
30. 2A adenosine receptor genes show similarities to mice given long-term caffeine. J. Appl. Physiol. 2009, 106:631-639.
31. 1 receptors. Acta Physiol. 2007, 190:63-75.