메뉴 건너뛰기




Volumn 674, Issue 2-3, 2012, Pages 337-344

Effects of MDMA and related analogs on plasma 5-HT: Relevance to 5-HT transporters in blood and brain

Author keywords

5 HT (serotonin); Blood; Brain; MDMA; Microdialysis; Platelet; SERT (serotonin transporter)

Indexed keywords

3 O METHYL ALPHA METHYLDOPAMINE; 3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 HYDROXY 3 METHOXYMETHAMPHETAMINE; AMPHETAMINE DERIVATIVE; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

EID: 84855523883     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.033     Document Type: Article
Times cited : (24)

References (37)
  • 1
    • 33751230490 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: A reappraisal of past and present findings
    • DOI 10.1007/s00213-006-0322-6, MDMA (Ecstasy)
    • Baumann, M.H., Wang, X., Rothman, R.B., 2007. 3,4- Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings. Psychopharmacology 189, 407-424. (Pubitemid 44791212)
    • (2007) Psychopharmacology , vol.189 , Issue.4 , pp. 407-424
    • Baumann, M.H.1    Wang, X.2    Rothman, R.B.3
  • 2
    • 41049096536 scopus 로고    scopus 로고
    • Tolerance to 3,4-methylenedioxymethamphetamine (MDMA) in rats exposed to single high-dose binges
    • Baumann, M.H., Clark, R.D., Franken, F.H., Rutter, J.J., Rothman, R.B., 2008. Tolerance to 3,4-methylenedioxymethamphetamine (MDMA) in rats exposed to single high-dose binges. Neuroscience 152, 773-784.
    • (2008) Neuroscience , vol.152 , pp. 773-784
    • Baumann, M.H.1    Clark, R.D.2    Franken, F.H.3    Rutter, J.J.4    Rothman, R.B.5
  • 3
    • 70350330871 scopus 로고    scopus 로고
    • Effects of dose and route of administration on pharmacokinetics of (+/-)-3,4-methylenedioxymethamphetamine in the rat
    • Baumann, M.H., Zolkowska, D., Kim, I., Scheidweiler, K.B., Rothman, R.B., Huestis, M.A., 2009. Effects of dose and route of administration on pharmacokinetics of (+/-)-3,4-methylenedioxymethamphetamine in the rat. Drug Metab. Dispos. 37, 2163-2170.
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 2163-2170
    • Baumann, M.H.1    Zolkowska, D.2    Kim, I.3    Scheidweiler, K.B.4    Rothman, R.B.5    Huestis, M.A.6
  • 4
    • 33845942152 scopus 로고    scopus 로고
    • Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?
    • DOI 10.1378/chest.130.6.1657
    • Chin, K.M., Channick, R.N., Rubin, L.J., 2006. Is methamphetamine use associated with idiopathic pulmonary arterial hypertension? Chest 130, 1657-1663. (Pubitemid 46033416)
    • (2006) Chest , vol.130 , Issue.6 , pp. 1657-1663
    • Chin, K.M.1    Channick, R.N.2    Rubin, L.J.3
  • 5
    • 0030796047 scopus 로고    scopus 로고
    • 2+-dependent 5-HT and dopamine release induced by(+)-amphetamine, 3,4,-methylendioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine
    • DOI 10.1038/sj.bjp.0701325
    • Crespi, D., Mennini, T., Gobbi, M., 1997. Carrier-dependent and Ca(2+)-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylendioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine. Br. J. Pharmacol. 121, 1735-1743. (Pubitemid 27343404)
    • (1997) British Journal of Pharmacology , vol.121 , Issue.8 , pp. 1735-1743
    • Crespi, D.1    Mennini, T.2    Gobbi, M.3
  • 7
    • 53849130971 scopus 로고    scopus 로고
    • Pulmonary hypertension: Therapeutic targets within the serotonin system
    • Dempsie, Y., MacLean, M.R., 2008. Pulmonary hypertension: therapeutic targets within the serotonin system. Br. J. Pharmacol. 155, 455-462.
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 455-462
    • Dempsie, Y.1    MacLean, M.R.2
  • 8
    • 34648831594 scopus 로고    scopus 로고
    • Neuroimaging of the serotonin reuptake site requires high-affinity ligands
    • DOI 10.1002/syn.20443
    • Elkving, B., Madsen, J., Knudsen, G.M., 2007. Neuroimaging of the serotonin reuptake site requires high-affinity ligands. Synapse 61, 882-888. (Pubitemid 47464084)
    • (2007) Synapse , vol.61 , Issue.11 , pp. 882-888
    • Elfving, B.1    Madsen, J.2    Knudsen, G.M.3
  • 9
    • 13444269027 scopus 로고    scopus 로고
    • A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice
    • DOI 10.1038/sj.bjp.0706071
    • Escobedo, I., O'Shea, E., Orio, L., Sanchez, V., Segura, M., de la Torre, R., Farre, M., Green, A.R., Colado, M.I., 2005. A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine on brain monoamine levels after i.p. or striatal administration in mice. Br. J. Pharmacol. 144, 231-241. (Pubitemid 40216121)
    • (2005) British Journal of Pharmacology , vol.144 , Issue.2 , pp. 231-241
    • Escobedo, I.1    O'Shea, E.2    Orio, L.3    Sanchez, V.4    Segura, M.5    De La, T.R.6    Farre, M.7    Green, A.R.8    Colado, M.I.9
  • 10
    • 66749120158 scopus 로고    scopus 로고
    • Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and its enantiomers in mice: Pharmacokinetic considerations
    • Fantegrossi, W.E., Murai, N., Mathúna, B.O., Pizarro, N., de la Torre, R., 2009. Discriminative stimulus effects of 3,4- methylenedioxymethamphetamine and its enantiomers in mice: pharmacokinetic considerations. J. Pharmacol. Exp. Ther. 329, 1006-1015.
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 1006-1015
    • Fantegrossi, W.E.1    Murai, N.2    Mathúna, B.O.3    Pizarro, N.4    De La Torre, R.5
  • 11
    • 0036183351 scopus 로고    scopus 로고
    • The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from isolated rat hypothalamus
    • Forsling, M.L., Fallon, J.K., Shah, D., Tilbrook, G.S., Cowan, D.A., Kicman, A.T., Hutt, A.J., 2002. The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from isolated rat hypothalamus. Br. J. Pharmacol. 135, 649-658.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 649-658
    • Forsling, M.L.1    Fallon, J.K.2    Shah, D.3    Tilbrook, G.S.4    Cowan, D.A.5    Kicman, A.T.6    Hutt, A.J.7
  • 12
    • 40949119918 scopus 로고    scopus 로고
    • The relationship between core body temperature and 3,4- methylenedioxymethamphetamine metabolism in rats: Implications for neurotoxicity
    • Goni-Allo, B., Mathuna, B.O., Segura, M., Puerta, E., Lasheras, B., de la Torre, R., Aguirre, N., 2008. The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicity. Psychopharmacology 197, 263-278.
    • (2008) Psychopharmacology , vol.197 , pp. 263-278
    • Goni-Allo, B.1    Mathuna, B.O.2    Segura, M.3    Puerta, E.4    Lasheras, B.5    De La Torre, R.6    Aguirre, N.7
  • 13
    • 0030070015 scopus 로고    scopus 로고
    • Carrier-mediated release of serotonin by 3,4- methylenedioxymethamphetamine: Implications for serotonin-dopamine interactions
    • Gudelsky, G.A., Nash, J.F., 1996. Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions. J. Neurochem. 66, 243-249.
    • (1996) J. Neurochem. , vol.66 , pp. 243-249
    • Gudelsky, G.A.1    Nash, J.F.2
  • 14
    • 0034176712 scopus 로고    scopus 로고
    • A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity
    • DOI 10.1016/S0006-3223(99)00171-7, PII S0006322399001717
    • Heinz, A., Jones, D.W., Mazzanti, C., Goldman, D., Ragan, P., Hommer, D., Linnoila, M., Weinberger, D.R., 2000. A relationship between serotonin transporter genotype, in vivo protein expression and alcohol neurotoxicity. Biol. Psychiatry 47, 643-649. (Pubitemid 30169258)
    • (2000) Biological Psychiatry , vol.47 , Issue.7 , pp. 643-649
    • Heinz, A.1    Jones, D.W.2    Mazzanti, C.3    Goldman, D.4    Ragan, P.5    Hommer, D.6    Linnoila, M.7    Weinberger, D.R.8
  • 16
    • 77958022683 scopus 로고    scopus 로고
    • Development of effective PET and SPECT imaging agents for the serotonin transporter: Has a twenty-year journey reached its destination?
    • Huang, Y., Zheng, M.Q., Gerdes, J.M., 2010. Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination? Curr. Top. Med. Chem. 10, 1499-1526.
    • (2010) Curr. Top. Med. Chem. , vol.10 , pp. 1499-1526
    • Huang, Y.1    Zheng, M.Q.2    Gerdes, J.M.3
  • 17
    • 47249166411 scopus 로고    scopus 로고
    • Plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine after controlled oral administration to young adults
    • Kolbrich, E.A., Goodwin, R.S., Gorelick, D.A., Hayes, R.J., Stein, E.A., Huestis, M.A., 2008. Plasma pharmacokinetics of 3,4- methylenedioxymethamphetamine after controlled oral administration to young adults. Ther. Drug Monit. 30, 320-332.
    • (2008) Ther. Drug Monit. , vol.30 , pp. 320-332
    • Kolbrich, E.A.1    Goodwin, R.S.2    Gorelick, D.A.3    Hayes, R.J.4    Stein, E.A.5    Huestis, M.A.6
  • 18
    • 0035674880 scopus 로고    scopus 로고
    • Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies
    • DOI 10.1002/hup.348
    • Liechti, M.E., Vollenweider, F.X., 2001. Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies. Hum. Psychopharmacol. 16, 589-598. (Pubitemid 34036939)
    • (2001) Human Psychopharmacology , vol.16 , Issue.8 , pp. 589-598
    • Liechti, M.E.1    Vollenweider, F.X.2
  • 20
    • 77956034606 scopus 로고    scopus 로고
    • Molecular mechanisms of SERT in platelets: Regulation of plasma serotonin levels
    • Mercado, C.P., Kilic, F., 2010. Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels. Mol. Interv. 10, 231-241.
    • (2010) Mol. Interv. , vol.10 , pp. 231-241
    • Mercado, C.P.1    Kilic, F.2
  • 21
    • 33745124642 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine in the cardiovascular system: Focus on the serotonin transporter (SERT)
    • DOI 10.1111/j.1440-1681.2006.04410.x
    • Ni, W., Watt, S.W., 2006. 5-Hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT). Clin. Exp. Pharmacol. Physiol. 33, 575-583. (Pubitemid 43894017)
    • (2006) Clinical and Experimental Pharmacology and Physiology , vol.33 , Issue.7 , pp. 575-583
    • Ni, W.1    Watts, S.W.2
  • 23
    • 0035669358 scopus 로고    scopus 로고
    • Human psychopharmacology of Ecstasy (MDMA): A review of 15 years of empirical research
    • DOI 10.1002/hup.351
    • Parrott, A.C., 2001. Human psychopharmacology of ecstasy (MDMA): a review of 15 years of empirical research. Hum. Psychopharmacol. 16, 557-577. (Pubitemid 34040989)
    • (2001) Human Psychopharmacology , vol.16 , Issue.8 , pp. 557-577
    • Parrott, A.C.1
  • 25
    • 21344469121 scopus 로고    scopus 로고
    • Serotonin transport kinetics correlated between human platelets and brain synaptosomes
    • DOI 10.1007/s00213-005-2178-6
    • Rausch, J.L., Johnson, M.E., Li, J., Hutcheson, J., Carr, B.M., Corley, K.M., Gowans, A.B., Smith, J., 2005. Serotonin transport kinetics correlated between human platelets and brain synaptosomes. Psychopharmacology 180, 391-398. (Pubitemid 40905028)
    • (2005) Psychopharmacology , vol.180 , Issue.3 , pp. 391-398
    • Rausch, J.L.1    Johnson, M.E.2    Li, J.3    Hutcheson, J.4    Carr, B.M.5    Corley, K.M.6    Gowans, A.B.7    Smith, J.8
  • 26
    • 66149087730 scopus 로고    scopus 로고
    • A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters
    • Robertson, S.D., Matthies, H.J.G., Galli, A., 2009. A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters. Mol. Neurobiol. 39, 73-80.
    • (2009) Mol. Neurobiol. , vol.39 , pp. 73-80
    • Robertson, S.D.1    Matthies, H.J.G.2    Galli, A.3
  • 27
    • 35448942332 scopus 로고    scopus 로고
    • Methamphetamine and idiopathic pulmonary arterial hypertension: Role of the serotonin transporter [14]
    • DOI 10.1378/chest.07-0235
    • Rothman, R.B., Baumann, M.H., 2007. Methamphetamine and idiopathic pulmonary arterial hypertension: role of the serotonin transporter. Chest 132, 1412-1413. (Pubitemid 47621034)
    • (2007) Chest , vol.132 , Issue.4 , pp. 1412-1413
    • Rothman, R.B.1    Baumann, M.H.2
  • 28
    • 0033600538 scopus 로고    scopus 로고
    • Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates: Implications for primary pulmonary hypertension
    • Rothman, R.B., Ayestas, M.A., Dersch, C.M., Baumann, M.H., 1999. Aminorex, fenfluramine and chlorphentermine are serotonin transporter substrates. Implications for pulmonary hypertension. Circulation 100, 869-875. (Pubitemid 29398887)
    • (1999) Circulation , vol.100 , Issue.8 , pp. 869-875
    • Rothman, R.B.1    Ayestas, M.A.2    Dersch, C.M.3    Baumann, M.H.4
  • 29
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman, R.B., Baumann, M.H., Dersch, C.M., Romero, D.V., Rice, K.C., Carroll, F.I., Partilla, J.S., 2001. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39, 32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 31
    • 0026546876 scopus 로고
    • The molecular mechanism of "ecstasy" [3,4- methylenedioxymethamphetamine (MDMA)]: Serotonin transporters are targets for MDMA-induced serotonin release
    • Rudnick, G., Wall, S.C., 1992. The molecular mechanism of "ecstasy" [3,4-methylenedioxymethamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release. Proc. Natl. Acad. Sci. 89, 1817-1821.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 1817-1821
    • Rudnick, G.1    Wall, S.C.2
  • 32
    • 0027731280 scopus 로고
    • Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters
    • Schuldiner, S., Steiner-Mordoch, S., Yelin, R., Wall, S.C., Rudnick, G., 1993. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters. Mol. Pharmacol. 44, 1227-1231. (Pubitemid 24008607)
    • (1993) Molecular Pharmacology , vol.44 , Issue.6 , pp. 1227-1231
    • Schuldiner, S.1    Steiner-Mordoch, S.2    Yelin, R.3    Wall, S.C.4    Rudnick, G.5
  • 33
    • 72849113289 scopus 로고    scopus 로고
    • - coupled neurotransmitter transporters: Why amphetamines take two to tango
    • - coupled neurotransmitter transporters: why amphetamines take two to tango. J. Neurochem. 112, 340-355.
    • (2010) J. Neurochem. , vol.112 , pp. 340-355
    • Sitte, H.H.1    Freissmuth, M.2
  • 35
    • 33751237085 scopus 로고    scopus 로고
    • MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: Implications for MDMA-induced neurotoxicity and treatment
    • DOI 10.1007/s00213-005-0174-5, MDMA (Ecstasy)
    • Verrico, C.D., Miller, G.M., Madras, B.K., 2007. MDMA (Ecstasy) and human dopamine, norepinephrine and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment. Psychopharmacology 189, 489-503. (Pubitemid 44791219)
    • (2007) Psychopharmacology , vol.189 , Issue.4 , pp. 489-503
    • Verrico, C.D.1    Miller, G.M.2    Madras, B.K.3
  • 36
    • 34548700385 scopus 로고    scopus 로고
    • 2 formation
    • DOI 10.1016/j.thromres.2007.01.007, PII S0049384807000369
    • Viisoreanu, D., Gear, A., 2007. Effect of physiologic shear stresses and calcium on agonist-induced platelet aggregation, secretion and thromboxane A2 formation. Thromb. Res. 120, 885-892. (Pubitemid 47418229)
    • (2007) Thrombosis Research , vol.120 , Issue.6 , pp. 885-892
    • Viisoreanu, D.1    Gear, A.2
  • 37
    • 33745947405 scopus 로고    scopus 로고
    • Amphetamine analogs increase plasma serotonin: Implications for cardiac and pulmonary disease
    • DOI 10.1124/jpet.106.101618
    • Zolkowska, D., Rothman, R.B., Baumann, M.H., 2006. Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease. J. Pharmacol. Exp. Ther. 318, 604-610. (Pubitemid 44061235)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.318 , Issue.2 , pp. 604-610
    • Zolkowska, D.1    Rothman, R.B.2    Baumann, M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.