Cell proliferation regulated by estradiol receptor: Therapeutic implications

Steroids

Volumn 75, Issue 8-9, 2010, Pages 524-527

  Castoria, Gabriella ^a   Migliaccio, Antimo ^a   Giovannelli, Pia ^a   Auricchio, Ferdinando ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Breast cancer therapy; Estradiol receptor; Non genomic action; Nuclear export; Specific interfering peptides

Indexed keywords

ALANYLCYSTEINYLGLUTAMYLPHENYLALANYLVALYLCYSTEINYLLEUCYLLYSYLSERYLISOLEUCYLISOLEUCYLLEUCYLLEUCYLASPARAGINYLSERYLALANYLALANYLALANYLARGINYLLYSYLLYSYLARGINYLARGINYLGLUTAMINYLARGINYLARGINYLARGINYLAMIDE; ALANYLCYSTEINYLLEUCYLTYROSYLASPARTYLLEUCYLLEUCYLLEUCYLAMIDE; ANTINEOPLASTIC AGENT; CYCLIN D1; ESTRADIOL; ESTRADIOL RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPEPTIDE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELLULAR DISTRIBUTION; CONFERENCE PAPER; DNA SYNTHESIS; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ESTROGEN ACTIVITY; GENE EXPRESSION REGULATION; GENETIC MODEL; HUMAN; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR EXPORT SIGNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR; UPREGULATION; BREAST TUMOR; GENETICS; METABOLISM;

BREAST NEOPLASMS; CELL PROLIFERATION; HUMANS; RECEPTORS, ESTRADIOL; SRC-FAMILY KINASES;

EID: 77954243044     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2009.10.007     Document Type: Conference Paper

References (27)

1. A.E. Gururaj, S.K. Rayala, R.K. Vadlamudi, and R. Kumar Novel mechanisms of resistance to endocrine therapy: genomic and nongenomic considerations Clin Cancer Res 12 2006 1001s 1007s
2. J.S. Biscardi, R.C. Ishizawar, C.M. Silva, and S.J. Parsons Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer Breast Cancer Res 2 2000 203 210
3. M. Beato, P. Herrlich, and G. Schütz Steroid hormone receptors: many actors in search of a plot Cell 83 1995 851 857
4. A. Migliaccio, G. Castoria, and F. Auricchio Src-dependent signalling pathway regulation by sex-steroid hormones: therapeutic implications Int J Biochem Cell Biol 39 2007 1343 1348
5. A. Migliaccio, M. Di Domenico, G. Castoria, M. Nanayakkara, M. Lombardi, and A. de Falco Steroid receptor regulation of EGF signaling through Src in breast and prostate cancer cells: steroid antagonist action Cancer Res 65 2005 10585 10593
6. G. Castoria, M.V. Barone, M. Di Domenico, A. Bilancio, D. Ametrano, and A. Migliaccio Non-transcriptional action of estrogen and progestin triggers DNA synthesis EMBO J 18 1999 2500 2510
7. G. Castoria, A. Migliaccio, A. Bilancio, M. Di Domenico, A. de Falco, and M. Lombardi PI3-kinase in concert with Src promotes the S-phase entry of estradiol-stimulated MCF-7 cells EMBO J 20 2001 6050 6059
8. G. Castoria, A. Migliaccio, M. Di Domenico, M. Lombardi, A. de Falco, and L. Varricchio Role of atypical PKC in estradiol-triggered G1/S progression of MCF-7 cells Mol Cell Biol 24 2004 7643 7653
9. M. Lombardi, G. Castoria, A. Migliaccio, M.V. Barone, R. Di Stasio, and A. Ciociola Hormone-dependent nuclear export of estradiol receptor and DNA synthesis in breast cancer cells J Cell Biol 182 2008 327 340
10. M. Le Romancer, I. Treilleux, N. Leconte, Y. Robein-Lespinasse, S. Sentis, and K. Bouchekioua-Bouzaghou Regulation of estrogen rapid signaling through arginine methylation by PRMT1 Mol Cell 31 2008 212 221
11. L. Varricchio, A. Migliaccio, G. Castoria, H. Yamaguchi, A. de Falco, and M. Di Domenico Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor {alpha} tyrosine-phosphorylated peptide Mol Cancer Res 11 2007 1213 1221
12. G. Castoria, A. Migliaccio, L. D'Amato, R. Di Stasio, A. Ciociola, and M. Lombardi Integrating signals between cAMP and MAPK pathways in breast cancer Front Biosci 13 2008 1318 1327
13. A. Migliaccio, M. Di Domenico, G. Castoria, A. de Falco, P. Bontempo, and E. Nola Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells EMBO J 15 1996 1292 1300
14. A. Migliaccio, D. Piccolo, G. Castoria, M. Di Domenico, A. Bilancio, and M. Lombardi Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor EMBO J 17 1998 2008 2018
15. A. Migliaccio, G. Castoria, M. Di Domenico, A. de Falco, A. Bilancio, and M. Lombardi Steroid-induced androgen receptor-oestradiol receptor beta Src complex triggers prostate cancer cell proliferation EMBO J 19 2000 5406 5417
16. A. Migliaccio, M. Pagano, and F. Auricchio Immediate and transient stimulation of protein tyrosine phosphorylation by estradiol in MCF-7 cells Oncogene 8 1993 2183 2191
17. S.R. Hammes, and E.R. Levin Extranuclear steroid receptors: nature and actions Endocr Rev 28 2007 726 741
18. K.U. Birkenkamp, and P.J. Coffer Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors Biochem Soc Trans 31 2003 292 297
19. W.H. Biggs 3rd, J. Meisenhelder, T. Hunter, W.K. Cavenee, and K.C. Arden Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 Proc Natl Acad Sci USA 96 1999 7421 7426
20. N. Nakamura, S. Ramaswamy, F. Vazquez, S. Signoretti, M. Loda, and W.R. Sellers Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN Mol Cell Biol 20 2000 8969 8982
21. kip1 Nature 404 2000 782 787
22. M. Schmidt, S.F. de Mattos, A. van der Horst, R. Klompmaker, G.J.P.L. Kops, and E.W.F. Lam Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D1 Mol Cell Biol 22 2002 7842 7852
23. S. Ramaswamy, N. Nakamura, I. Sansal, L. Bergeron, and W.R. Sellers A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR Cancer Cell 2 2002 81 91
24. F. Auricchio, A. Migliaccio, and G. Castoria Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors Steroids 73 2008 880 884
25. G. Castoria, A. Migliaccio, and F. Auricchio Signaling-dependent nuclear export of estradiol receptor controls cell cycle progression in breast cancer cells Mol Cell Endocrinol 308 2009 26 31
26. A. Joliot, and A. Prochiantz Transduction peptides: from technology to physiology Nat Cell Biol 6 2004 189 196
27. R. Kumar, R.A. Wang, A. Mazumdar, A.H. Talukder, M. Mandal, and Z. Yang A naturally occurring MTA1 variant sequesters oestrogen receptor-alpha in the cytoplasm Nature 418 2002 654 657