Synthesis and cytotoxicity evaluation of phosphorylated derivatives of ribavirin

Journal of the Korean Chemical Society

Volumn 55, Issue 6, 2011, Pages 952-959

  Rao, Valasani Koteswara ^a   Reddy, Sanapalli Subba ^a   Babu, Kilaru Raveendra ^a   Kumar, Kuntrapakam Hema ^b   Ghosh, Sunil Kumar ^c   Raju, Chamarthi Naga ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b Aptus Biosciences Private Limited   (India)

^c BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

MCF 7 cell lines; MTT assay; Phosphorylated ribavirins; Trypan blue assay

Indexed keywords

AMINO ACID ESTERS; ANTICANCER ACTIVITIES; IN-VITRO; MASS-SPECTRAL ANALYSIS; MCF-7 BREAST CANCER CELLS; MCF-7 CELLS; MTT ASSAYS; PHOSPHORYLATED DERIVATIVES; PHOSPHORYLATED RIBAVIRINS; RIBAVIRIN; TETRA-HYDROFURAN; TITLE COMPOUNDS; TRIETHYLAMINES;

AMIDES; AMINO ACIDS; CELL CULTURE; ORGANIC SOLVENTS; REACTION INTERMEDIATES; SPECTRUM ANALYSIS; SYNTHESIS (CHEMICAL);

PHOSPHORYLATION;

EID: 84855451440     PISSN: 10172548     EISSN: None     Source Type: Journal    
DOI: 10.5012/jkcs.2011.55.6.952     Document Type: Article

References (25)

1. Albrand, G.; Terret, C. Drugs Aging. 2008, 25, 35.
2. Labrie, F.; Labrie, C.; Belanger, A.; Simard, J.; Gauthier, S.; Luu-The, V.; Merand, Y.; Giguere, V.; Candas, B.; Luo, S.; Martel, C.; Singh, S. M.; Fournier, M.; Coquet, A.; Richard, V.; Charbonneau, R.; Charpenet, G.; Tremblay, A.; Tremblay, G.; Cusan, L.; Veilleux, R. J. Steroid Biochem. Mol. Biol. 1999, 69, 51.
3. The American Cancer Society Web page. Breast Cancer Facts & Figures 2005-2006. http://www.cancer.org/downloads/STT/CAFF2005BrF.pdf
4. Baumann, C. K.; Castiglione-Gertsch, M. Drugs. 2007, 67, 2335.
5. Ikeda, K.; Inoue, S. Arch. Histol. Cytol. 2004, 67, 435.
6. Hobbs, J. B. Comprehensive Medicinal Chemistry, Sammes P.G., Ed, Pergamon Press: Oxford, 1990; Vol. 2, pp 299-305.
7. Riley, T. A.; Larson, S. B.; Avery, T. L.; Finch, R. A.; Robins, R. K. J. Med. Chem. 1990, 33, 572.
8. Smith, R. A.; Kirkpatrick, W. Ribavirin A Broad Spectrum Antiviral Agent; Academic Press: New York, 1980; p 231.
9. Smith, R. A.; Knight, V.; Smith, J. A. D. Clinical Applications of Ribavirin; Academic Press: New York, 1984; p 203.
10. Sidwell, R. W.; Revankar, G. R.; Robins, R. K. In Viral Chemotherapy; D.; Shugar, Ed.; Pergamon Press: New York, 1985; Vol. 2; p 49.
11. McCormick, J. B.; Getchell, J. P.; Mitchell, S. W.; Hicks, D. R. Lancet ii. 1984, 1367.
12. Witkowski, J. T.; Robins, R. K.; Khare, G. P.; Sidwell, R. W. J. Med. Chem. 1973, 16, 937.
13. Sanghvi, Y. S.; Hanna, N. B.; Larson, S. B.; Robins, R. K. revankar, G. R. Nucleosides, Nucleotides Nucleic Acids 1987, 6, 761.
14. Franchetti, P.; Grifantini, M. Curr. Med. Chem. 1999, 6, 599.
15. Ibarrola, N.; Moreno-Monteagudo, J.A.; Sáiz, M.; Garcia Monzon, C.; Sobrino, F.; Garcia Buey, L.; Lo Iacono, O.; Moreno Otero, R.; Martinez Salas, E. Am. J. Gastroenterol. 1999, 94, 2487.
16. Armarego, W. L. F.; Perrin, D. D. Purification of Laboratory Chemicals, 4th ed.; Butterworth-Heinemann, Oxford OX2 8DP, 1997.
17. Freshney, R. Culture of Animal Cells: A Manual of Basic Techniques, Alan R. Liss, Inc.: New York, 1987; p 117.
18. Alley, M. C.; Scudiero, D. A.; Anne, M.; Hursey, M. L.; Czerwinski, M. J.; Fine, D. L.; Abbott, B. J.; Mayo, J. G.; Shoemaker, R. H.; Boyd, M. R. Cancer Res. 1988, 48, 589.
19. Kiran, Y. B.; Devendranath Reddy, C.; Gunasekar, D.; Suresh Reddy, C.; Leon, A.; Barbosa, C. A. Eur. J. Med. Chem. 2008, 43, 885.
20. Kumar, R.; Semaine, W.; Johar, M.; Lorne, D.; Tyrrell, J.; Agrawal, B. J. Med. Chem. 2006, 12, 3693.
21. Khandazhinskaya, A.L.; Shirokova, E.A.; Skoblov, Y.S.; Victorova, L. S.; Goryunova, L. Y.; Beabealashvilli, R. S.; Pronyaeva, T. R.; Fedyuk, N. V.; Zolin, V. V.; Pokrovsky, A. G.; Kukhanova, M. K. J. Med. Chem. 2002, 6, 1284.
22. Han, S. Y.; Sweeney, J. E.; Bachman, E. S.; Schweiger E. J., Forlorin, G.; Coyle, J. T.; Davis, B. M.; Joullie, M. M. Eur. J. Med. Chem. 1992, 27, 673.
23. Zatorski, A.; Watanabe, A. K.; Carr, F. S.; Goldstein, M. B.; Pankiewicz, W. K. J. Med. Chem. 1996, 39, 2422.
24. Lois, B.; Allen, K. H.; Boswell, Khwaja, A.; Meyer, B.; Robert, Jr.; Sidwell, W.; Witkowski, J. T. J. Med. Chem. 1978, 21, 742.
25. Wang, R.; Harada, S.; Mitsuya, H.; Zemlicka, J. J. Med. Chem. 2003, 22, 4799.