Synthesis and anticancer activity of new class of bisphosphonates/phosphanamidates

European Journal of Medicinal Chemistry

Volumn 43, Issue 4, 2008, Pages 885-892

  Kiran, Y B ^a   Devendranath Reddy, C ^a   Gunasekar, D ^a   Suresh Reddy, C ^a   Leon, Annette ^b   Barbosa, Luiz C A ^c  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

Author keywords

Adenocarcinoma; Bisphosphanamidates; Bisphosphonates; Cytotoxicity; Glioblastoma; Pudovick reaction

Indexed keywords

[(4 CHLOROPHENYL)(HYDROXYAMIDOPHOSPHINOYL)METHYL]PHOSPHONIC ACID; ANTINEOPLASTIC AGENT; BISPHOSPHONAMIDATE DERIVATIVE; BISPHOSPHONIC ACID DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG SYNTHESIS; GLIOBLASTOMA; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS; HUMANS; HYDROCARBONS, CHLORINATED; MOLECULAR STRUCTURE; NEOPLASMS; PHOSPHONIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 41249085021     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.05.014     Document Type: Article

References (22)

1. In: Blomen L.J.M.J., Bijuoet O.L.M., Fleisch H.A., Canfield R.E., and Russell R.G.G. (Eds). History of the Bisphosphonates: Discovery and History of the Non-Medical Uses of Bisphosphonates (1995), Elsevier, Amsterdam 111-124
2. Fleish H., Russel R.G., and Straumann F. Nature 212 (1966) 901-903
3. Francis M.D., Russel R.G., and Fleish H. Science 165 (1969) 1264-1266
4. Fleisch H., Russel R.G., and Francis M.D. Science 165 (1969) 1262-1264
5. Widler L., Jaeggi K.A., Glatt M., Muller K., Bachmann R., Bisping M., Born A.-R., Cortesi R., Guiglia G., Jeker H., Klein R., Ramseier U., Schmid J., Schreiber G., Seltenmeyer Y., and Green J.R. J. Med. Chem. 45 (2002) 3721-3738
6. Nugent R.A., Schlachter S.T., Murphy M., Dunn C.J., Staite N.D., Galinet L.A., Shields S.K., Wu H., Aspar D.G., and Richard K.A. J. Med. Chem. 37 (1994) 4449-4454
7. Nugent R.A., Murphy M., Schlachter S.T., Dunn C.J., Smith R.J., Staite N.D., Galinet L.A., Shields S.K., Aspar D.G., Richard K.A., and Rohloff N.A. J. Med. Chem. 36 (1993) 134-139
8. Martin M.B., Sanders J.M., Kendrick H., de Luca-Fradley K., Lewis J.C., Grimley J.S., Van Brussel E.M., Olsen J.R., Meints G.A., Burzynska A., Kafarski P., Croft S.L., and Oldfield E. J. Med. Chem. 45 (2002) 2904-2914
9. Mundy G.R., and Yoneda T. New Engl. J. Med. 339 (1998) 398-400
10. Mc Kenng C.E., Khawli L.A., Levy J.N., Harutumian V., Ye T.G., Bapat A., Starnes M.C., and Cheng Y.C. ACS Symp. Ser. 401 (1989) 1
11. Lisic E.C., Philips M., Eusor D., Nash K.L., Beets A., and Knapp Jr. F.F. Nucl. Med. Biol. 28 (2001) 419-424
12. Pudovik A.N. Chemistry of Organophosphorus Compounds (1989), MIR Publishers, Moscow p. 110
13. Kiran Y.B., Gunasekar D., Reddy C.D., Reddy C.S., Tran K., Thane L., Berlin K.D., Srinivasan K., and Devi M.C. Pest Manag. Sci. 61 (2005) 1016-1023
14. Silverstein R.M., and Webster F.X. Spectrometric Identification of Organic Compounds. sixth ed. (1998), John Wiley & Sons, New York
15. Reddy P.V.G., Reddy C.S., and Venugopal M. Heteroat. Chem. 14 (2003) 509-512
16. Furniss B.S., Hannaford A.J., Smith P.W.G., and Tatchell A.R. Vogel's Text Book of Practical Organic Chemistry. fifth ed. (1989), Addison Wesley Longman Inc., Harlow
17. Zwierzak A. Can. J. Chem. 45 (1967) 2501-2512
18. Muthiah C., Kumar K.P., Mani C.A., and Swamy K.C.K. J. Org. Chem. 65 (2000) 3733-3737
19. Cristau H.-J., Brahic C., and Pirat J.-L. Tetrahedron 57 (2001) 9149-9156
20. Herczegh P., Buxton T.B., McPherson III J.C., Kulyassa A.K., Brewer P.D., Sztaricskai F., Sterebel G.G., Polwman K.M., Farcasiu D., and Hartmann J.F. J. Med. Chem. 45 (2002) 2338-2341
21. ATCC, 2001, posting date. MTT cell proliferation assay. ATCC, Manassas, VA. .
22. Software for Windows, GraphPad Software Inc., SanDiego, CA. .