Carbocyclic dinucleoside polyphosphonates: Interaction with HIV reverse transcriptase and antiviral activity

Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2002, Pages 1284-1291

  Khandazhinskaya, Anastasya L ^a   Shirokova, Elena A ^a   Skoblov, Yurii S ^a   Victorova, Lyubov S ^a,b   Goryunova, Ludmila Ye ^c   Beabealashvilli, Robert S ^c   Pronyaeva, Tatyana R ^d   Fedyuk, Nina V ^d   Zolin, Vladimir V ^d   Pokrovsky, Andrey G ^d   Kukhanova, Marina K ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b UNIVERSITY OF OSLO   (Norway)

^c INSTITUTE OF EXPERIMENTAL CARDIOLOGY   (Russian Federation)

^d STATE RESEARCH CENTER OF VIROLOGY AND BIOTECHNOLOGY VECTOR   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC ALPHA,DELTA BIS(NUCLEOSIDE) 5,5' TETRAPHOSPHONATE; CARBOCYCLIC ALPHA,GAMMA BIS(NUCLEOSIDE) 5,5' TRIPHOSPHONATE; DNA; LIPOSOME; NUCLEOSIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CELL FREE SYSTEM; CHEMICAL INTERACTION; DNA SYNTHESIS INHIBITION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ENZYME SUBSTRATE; FIBROBLAST CULTURE; NONHUMAN; RAT;

ANIMALS; ANTI-HIV AGENTS; CELLS, CULTURED; CYCLOPENTANES; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; LIPOSOMES; NUCLEOSIDES; ORGANOPHOSPHORUS COMPOUNDS; RATS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037075818     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm011011l     Document Type: Article

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