miRNA expression profile in primary gastric cancers and paired lymph node metastases indicates that miR-10a plays a role in metastasis from primary gastric cancer to lymph nodes

Experimental and Therapeutic Medicine

Volumn 3, Issue 2, 2012, Pages 351-356

  Chen, Weidong ^a   Tang, Zhaoqing ^a   Sun, Yihong ^a   Zhang, Youyou ^a   Wang, Xuefei ^a   Shen, Zhenbin ^a   Liu, Fenglin ^a   Qin, Xinyu ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Gastric cancer; Lymph node metastasis; miR 10a

Indexed keywords

MICRORNA; MICRORNA 10A; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; DOWN REGULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; MALE; POLYMERASE CHAIN REACTION; PRIMARY GASTRIC CANCER; PRIMARY TUMOR; STOMACH CANCER; STOMACH MUCOSA; UPREGULATION;

EID: 84855435443     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2011.411     Document Type: Article

References (27)

1. Wightman B, Ha I and Ruvkun G: Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862, 1993.
2. Lee RC, Feinbaum RL and Ambros V: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854, 1993.
3. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
4. Calin GA and Croce CM: MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866, 2006.
5. Esquela-Kerscher A and Slack FJ: Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269, 2006.
6. Huang Q, Gumireddy K, Schrier M, et al: The microRNAs miR-373 and miR-520c promote tumor invasion and metastasis. Nat Cell Biol 10: 202-210, 2008.
7. Ma L and Weinberg RA: MicroRNAs in malignant progression. Cell Cycle 7: 570-572, 2008.
8. Chen C, Ridzon DA, Broomer AJ, et al: Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33: e179, 2005.
9. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method. Methods 25: 402-408, 2001.
10. Wang L, Zhu JS, Song MQ, et al: Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray. World J Gastroenterol 12: 6949-6954, 2006.
11. Mori M, Mimori K, Yoshikawa Y, et al: Analysis of the gene-expression profile regarding the progression of human gastric carcinoma. Surgery 131 (Suppl 1): S39-S47, 2002.
12. Ushijima T and Sasako M: Focus on gastric cancer. Cancer Cell 5: 121-125, 2004.
13. Onate-Ocana LF, Aiello-Crocifoglio V, Mondragon-Sanchez R, et al: Survival benefit of D2 lympadenectomy in patients with gastric adenocarcinoma. Ann Surg Oncol 7: 210-217, 2000.
14. + cells increase USF2-mediated cell growth. Mol Cancer Res 6: 1830-1840, 2008.
15. Zhang L, Huang J, Yang N, et al: MicroRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci USA 103: 9136-9141, 2006.
16. Jongen-Lavrencic M, Sun SM, Dijkstra MK, et al: MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia. Blood 111: 5078-5085, 2008.
17. Varnholt H, Drebber U, Schulze F, et al: MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma. Hepatology 47: 1223-1232, 2008.
18. Ma L, Teruya-Feldstein J and Weinberg RA: Tumor invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688, 2007.
19. Ma L, Reinhardt F, Weinberg RA, et al: Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 28: 341-347, 2010.
20. Weiss FU, Margues IJ, Woltering JM, et al: Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer. Gastroenterology 137: 2136-2145, 2009.
21. Li X, Zhang Y, Fan D, et al: Survival prediction of gastric cancer by a seven-microRNA signature. Gut 59: 579-585, 2010.
22. Ueda T, Volinia S, Okumura H, et al: Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol 11: 136-146, 2010.
23. Krek A, Grun D, Poy MN, et al: Combinatorial microRNA target predictions. Nat Genet 37: 495-500, 2005.
24. Lewis BP, Burge CB and Bartel DP: Conserved seed pairing, often flanked by adenosines indicates that thousands of human genes are microRNA targets. Cell 120: 15-20, 2005.
25. Megraw M, Sethupathy P, Corda B, et al: miRGen: a database for the study of animal microRNA genomic organization and function. Nucleic Acids Res 35: D149-D155, 2007.
26. Kanehisa M and Goto S: KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30, 2000.
27. Polakis P: Wnt signaling and cancer. Genes Dev 14: 1837-1851, 2000.