Serum amyloid P component facilitates DNA clearance and inhibits plasmid transfection: Implications for human DNA vaccine

Gene Therapy

Volumn 19, Issue 1, 2012, Pages 70-77

  Wang, Y ^a   Guo, Y ^a   Wang, X ^a   Huang, J ^a   Shang, J ^a   Sun, S ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

DNA vaccine; DNA binding proteins; immunogenicity; serum amyloid P component

Indexed keywords

AMYLOID P COMPONENT; DNA VACCINE; PLASMID DNA; PLASMID VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA CLEARANCE; DNA IMMUNIZATION; DNA PROTEIN COMPLEX; DNA TRANSFECTION; ENDOCYTOSIS; EXTRACELLULAR SPACE; FEMALE; GENE EXPRESSION; GENETIC PARAMETERS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGENICITY; MACROPHAGE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DNA BINDING; PROTEOMICS; SOMATIC CELL;

AMINO ACID SEQUENCE; ANIMALS; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOCYTOSIS; FEMALE; GENE EXPRESSION REGULATION; GENES, TAT; HEK293 CELLS; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HIV; HUMANS; IMMUNITY, CELLULAR; MACROPHAGES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEOMICS; SERUM AMYLOID P-COMPONENT; SPECIES SPECIFICITY; TRANSFECTION; VACCINATION; VACCINES, DNA;

MUS;

EID: 84855422153     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.67     Document Type: Article

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