-
1
-
-
0037389607
-
Critical role of oxidative stress in estrogen-induced carcinogenesis
-
Bhat,H.K. et al. (2003) Critical role of oxidative stress in estrogen-induced carcinogenesis. Proc. Natl. Acad. Sci. USA, 100, 3913-3918.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3913-3918
-
-
Bhat, H.K.1
-
2
-
-
10744225225
-
Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators
-
Cavalieri,E.L. et al. (1997) Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc. Natl. Acad. Sci. USA, 94, 10937-10942.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10937-10942
-
-
Cavalieri, E.L.1
-
3
-
-
0034099083
-
Hormonal carcinogenesis
-
Henderson,B.E. et al. (2000) Hormonal carcinogenesis. Carcinogenesis, 21, 427-433.
-
(2000)
Carcinogenesis
, vol.21
, pp. 427-433
-
-
Henderson, B.E.1
-
4
-
-
51549099366
-
Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure
-
Mense,S.M. et al. (2008) Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure. Toxicol. Appl. Pharmacol., 232, 78-85.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.232
, pp. 78-85
-
-
Mense, S.M.1
-
5
-
-
67650159397
-
Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats
-
Mense,S.M. et al. (2009) Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats. Carcinogenesis, 30, 1202-1208.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1202-1208
-
-
Mense, S.M.1
-
6
-
-
67649329396
-
Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats
-
Singh,B. et al. (2009) Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats. J. Biochem. Mol. Toxicol., 23, 202-211.
-
(2009)
J. Biochem. Mol. Toxicol.
, vol.23
, pp. 202-211
-
-
Singh, B.1
-
7
-
-
40749161927
-
The molecular etiology of breast cancer: evidence from biomarkers of risk
-
Gaikwad,N.W. et al. (2008) The molecular etiology of breast cancer: evidence from biomarkers of risk. Int. J. Cancer, 122, 1949-1957.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 1949-1957
-
-
Gaikwad, N.W.1
-
8
-
-
70249107870
-
Urine biomarkers of risk in the molecular etiology of breast cancer
-
Gaikwad,N.W. et al. (2009) Urine biomarkers of risk in the molecular etiology of breast cancer. Breast Cancer (Auckl), 3, 1-8.
-
(2009)
Breast Cancer (Auckl)
, vol.3
, pp. 1-8
-
-
Gaikwad, N.W.1
-
9
-
-
75149174413
-
Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers
-
Cavalieri,E.L. et al. (2010) Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers. Future Oncol., 6, 75-91.
-
(2010)
Future Oncol
, vol.6
, pp. 75-91
-
-
Cavalieri, E.L.1
-
10
-
-
0035945656
-
Estrogen and the risk of breast cancer
-
Clemons,M. et al. (2001) Estrogen and the risk of breast cancer. N. Engl. J. Med., 344, 276-285.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 276-285
-
-
Clemons, M.1
-
11
-
-
0033657888
-
Tissue-specific synthesis and oxidative metabolism of estrogens
-
Jefcoate,C.R. et al. (2000) Tissue-specific synthesis and oxidative metabolism of estrogens. J. Natl. Cancer Inst. Monogr., 27, 95-112.
-
(2000)
J. Natl. Cancer Inst. Monogr.
, vol.27
, pp. 95-112
-
-
Jefcoate, C.R.1
-
12
-
-
0027350669
-
32P-postlabelling in studies of hormonal carcinogenesis
-
Liehr,J.G. et al. (1993) 32P-postlabelling in studies of hormonal carcinogenesis. IARC Sci. Publ., 124, 149-155.
-
(1993)
IARC Sci. Publ.
, vol.124
, pp. 149-155
-
-
Liehr, J.G.1
-
13
-
-
0025313058
-
Free radical generation by redox cycling of estrogens
-
Liehr,J.G. et al. (1990) Free radical generation by redox cycling of estrogens. Free Radic. Biol. Med., 8, 415-423.
-
(1990)
Free Radic. Biol. Med.
, vol.8
, pp. 415-423
-
-
Liehr, J.G.1
-
14
-
-
30944469849
-
Estrogen carcinogenesis in breast cancer
-
Yager,J.D. et al. (2006) Estrogen carcinogenesis in breast cancer. N. Engl. J. Med., 354, 270-282.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 270-282
-
-
Yager, J.D.1
-
15
-
-
31844450313
-
The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity
-
Zahid,M. et al. (2006) The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity. Chem. Res. Toxicol., 19, 164-172.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 164-172
-
-
Zahid, M.1
-
16
-
-
0023181602
-
Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism
-
Li,J.J. et al. (1987) Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism. Fed. Proc., 46, 1858-1863.
-
(1987)
Fed. Proc.
, vol.46
, pp. 1858-1863
-
-
Li, J.J.1
-
17
-
-
0034650264
-
Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens
-
Newbold,R.R. et al. (2000) Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens. Cancer Res., 60, 235-237.
-
(2000)
Cancer Res
, vol.60
, pp. 235-237
-
-
Newbold, R.R.1
-
18
-
-
1542270862
-
Differential oxidant potential of carcinogenic and weakly carcinogenic estrogens: involvement of metabolic activation and cytochrome P450
-
Patel,M.M. et al. (2004) Differential oxidant potential of carcinogenic and weakly carcinogenic estrogens: involvement of metabolic activation and cytochrome P450. J. Biochem. Mol. Toxicol., 18, 37-42.
-
(2004)
J. Biochem. Mol. Toxicol.
, vol.18
, pp. 37-42
-
-
Patel, M.M.1
-
19
-
-
0022568510
-
Carcinogenicity of catechol estrogens in Syrian hamsters
-
Liehr,J.G. et al. (1986) Carcinogenicity of catechol estrogens in Syrian hamsters. J. Steroid Biochem., 24, 353-356.
-
(1986)
J. Steroid Biochem.
, vol.24
, pp. 353-356
-
-
Liehr, J.G.1
-
20
-
-
0033655698
-
Endogenous estrogens as carcinogens through metabolic activation
-
Yager,J.D. (2000) Endogenous estrogens as carcinogens through metabolic activation. J. Natl Cancer Inst. Monogr., 27, 67-73.
-
(2000)
J. Natl Cancer Inst. Monogr.
, vol.27
, pp. 67-73
-
-
Yager, J.D.1
-
21
-
-
1242319539
-
Chemoprevention by 1,2-dithiole-3-thiones through induction of NQO1 and other phase 2 enzymes
-
Kwak,M.K. et al. (2004) Chemoprevention by 1,2-dithiole-3-thiones through induction of NQO1 and other phase 2 enzymes. Methods Enzymol., 382, 414-423.
-
(2004)
Methods Enzymol
, vol.382
, pp. 414-423
-
-
Kwak, M.K.1
-
22
-
-
76249129074
-
Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors
-
Shen,J. et al. (2010) Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors. Cancer Res., 70, 1006-1014.
-
(2010)
Cancer Res.
, vol.70
, pp. 1006-1014
-
-
Shen, J.1
-
23
-
-
34548714650
-
Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones
-
Gaikwad,N.W. et al. (2007) Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones. Free Radic. Biol. Med., 43, 1289-1298.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 1289-1298
-
-
Gaikwad, N.W.1
-
24
-
-
60549118140
-
Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells
-
Lu,F. et al. (2008) Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells. Cancer Prev. Res. (Phila. Pa), 1, 135-145.
-
(2008)
Cancer Prev. Res. (Phila. Pa)
, vol.1
, pp. 135-145
-
-
Lu, F.1
-
25
-
-
0034531564
-
NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms
-
Ross,D. et al. (2000) NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms. Chem. Biol. Interact., 129, 77-97.
-
(2000)
Chem. Biol. Interact.
, vol.129
, pp. 77-97
-
-
Ross, D.1
-
26
-
-
44649133781
-
Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol
-
Zahid,M. et al. (2008) Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol. Free Radic. Biol. Med., 45, 136-145.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 136-145
-
-
Zahid, M.1
-
27
-
-
0034704137
-
Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H: quinone oxidoreductase1 gene
-
Dhakshinamoorthy,S. et al. (2000) Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H: quinone oxidoreductase1 gene. J. Biol. Chem., 275, 40134-40141.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40134-40141
-
-
Dhakshinamoorthy, S.1
-
28
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak,M.K. et al. (2003) Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem., 278, 8135-8145.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
-
29
-
-
37449000924
-
Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection
-
Reddy,N.M. et al. (2007) Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection. Physiol. Genomics, 32, 74-81.
-
(2007)
Physiol. Genomics
, vol.32
, pp. 74-81
-
-
Reddy, N.M.1
-
30
-
-
74049120454
-
Nrf2: friend or foe for chemoprevention?
-
Kensler,T.W. et al. (2010) Nrf2: friend or foe for chemoprevention? Carcinogenesis, 31, 90-99.
-
(2010)
Carcinogenesis
, vol.31
, pp. 90-99
-
-
Kensler, T.W.1
-
31
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler,T.W. et al. (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol., 47, 89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
-
32
-
-
73649134320
-
Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression
-
Kaspar,J.W. et al. (2010) Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression. J. Biol. Chem., 285, 153-162.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 153-162
-
-
Kaspar, J.W.1
-
33
-
-
22344441219
-
Antioxidant indices of some green leafy vegetables
-
Akindahunsi,A.A. et al. (2005) Antioxidant indices of some green leafy vegetables. Trop. Sci., 45, 33-35.
-
(2005)
Trop. Sci.
, vol.45
, pp. 33-35
-
-
Akindahunsi, A.A.1
-
34
-
-
0033547645
-
Treatment of hypertension with ascorbic acid
-
Duffy,S.J. et al. (1999) Treatment of hypertension with ascorbic acid. Lancet, 354, 2048-2049.
-
(1999)
Lancet
, vol.354
, pp. 2048-2049
-
-
Duffy, S.J.1
-
35
-
-
0037178573
-
Dietary intake of antioxidants and risk of Alzheimer disease
-
Engelhart,M.J. et al. (2002) Dietary intake of antioxidants and risk of Alzheimer disease. JAMA, 287, 3223-3229.
-
(2002)
JAMA
, vol.287
, pp. 3223-3229
-
-
Engelhart, M.J.1
-
36
-
-
0035799105
-
Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition
-
Khaw,K.T. et al. (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet, 357, 657-663.
-
(2001)
Lancet
, vol.357
, pp. 657-663
-
-
Khaw, K.T.1
-
37
-
-
0036280986
-
Plasma vitamin C modifies the association between hypertension and risk of stroke
-
Kurl,S. et al. (2002) Plasma vitamin C modifies the association between hypertension and risk of stroke. Stroke, 33, 1568-1573.
-
(2002)
Stroke
, vol.33
, pp. 1568-1573
-
-
Kurl, S.1
-
38
-
-
0035874967
-
Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
-
Lee,S.H. et al. (2001) Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Science, 292, 2083-2086.
-
(2001)
Science
, vol.292
, pp. 2083-2086
-
-
Lee, S.H.1
-
39
-
-
18844470060
-
Vitamin C exhibits pro-oxidant properties
-
Podmore,I.D. et al. (1998) Vitamin C exhibits pro-oxidant properties. Nature, 392, 559.
-
(1998)
Nature
, vol.392
, pp. 559
-
-
Podmore, I.D.1
-
40
-
-
0021271602
-
Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure
-
McCormick,D.L. et al. (1984) Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure. Cancer Res., 44, 2858-2863.
-
(1984)
Cancer Res.
, vol.44
, pp. 2858-2863
-
-
McCormick, D.L.1
-
41
-
-
0019955793
-
Comparative effects of dietary administration of 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on several hepatic enzyme activities in mice and rats
-
Cha,Y.N. et al. (1982) Comparative effects of dietary administration of 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on several hepatic enzyme activities in mice and rats. Cancer Res., 42, 2609-2615.
-
(1982)
Cancer Res.
, vol.42
, pp. 2609-2615
-
-
Cha, Y.N.1
-
42
-
-
0032861814
-
In vivo studies on butylated hydroxyanisole
-
Iverson,F. (1999) In vivo studies on butylated hydroxyanisole. Food Chem. Toxicol., 37, 993-997.
-
(1999)
Food Chem. Toxicol.
, vol.37
, pp. 993-997
-
-
Iverson, F.1
-
43
-
-
0028234634
-
DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy
-
Han,X. et al. (1994) DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy. Carcinogenesis, 15, 997-1000.
-
(1994)
Carcinogenesis
, vol.15
, pp. 997-1000
-
-
Han, X.1
-
44
-
-
13244295677
-
Suppression of calbindin D28K in estrogen-induced hamster renal tumors
-
Bhat,H.K. et al. (2004) Suppression of calbindin D28K in estrogen-induced hamster renal tumors. J. Steroid Biochem. Mol. Biol., 92, 391-398.
-
(2004)
J. Steroid Biochem. Mol. Biol.
, vol.92
, pp. 391-398
-
-
Bhat, H.K.1
-
45
-
-
44649093884
-
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin
-
Mense,S.M. et al. (2008) Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. J. Steroid Biochem. Mol. Biol., 110, 157-162.
-
(2008)
J. Steroid Biochem. Mol. Biol.
, vol.110
, pp. 157-162
-
-
Mense, S.M.1
-
46
-
-
0019142866
-
Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity
-
Benson,A.M. et al. (1980) Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc. Natl Acad. Sci. USA, 77, 5216-5220.
-
(1980)
Proc. Natl Acad. Sci. USA
, vol.77
, pp. 5216-5220
-
-
Benson, A.M.1
-
47
-
-
0029690878
-
Subcellular fractionation of animal tissues
-
Ryan,N.M. (1996) Subcellular fractionation of animal tissues. Methods Mol. Biol., 59, 49-56.
-
(1996)
Methods Mol. Biol.
, vol.59
, pp. 49-56
-
-
Ryan, N.M.1
-
48
-
-
0035584274
-
Importance of complete DNA digestion in minimizing variability of 8-oxo-dG analyses
-
Huang,X. et al. (2001) Importance of complete DNA digestion in minimizing variability of 8-oxo-dG analyses. Free Radic. Biol. Med., 31, 1341-1351.
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1341-1351
-
-
Huang, X.1
-
49
-
-
34249309939
-
Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis
-
Montano,M.M. et al. (2007) Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis. Oncogene, 26, 3587-3590.
-
(2007)
Oncogene
, vol.26
, pp. 3587-3590
-
-
Montano, M.M.1
-
50
-
-
79952281710
-
Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer
-
Patrick,B.A. et al. (2011) Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer. Oncogene, 30, 1098-1107.
-
(2011)
Oncogene
, vol.30
, pp. 1098-1107
-
-
Patrick, B.A.1
-
51
-
-
0034646213
-
Rat strain-specific actions of 17beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers
-
Harvell,D.M. et al. (2000) Rat strain-specific actions of 17beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers. Proc. Natl Acad. Sci. USA, 97, 2779-2784.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 2779-2784
-
-
Harvell, D.M.1
-
52
-
-
0036144435
-
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer
-
Li,J.J. et al. (2002) Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Mol. Carcinog., 33, 56-65.
-
(2002)
Mol. Carcinog.
, vol.33
, pp. 56-65
-
-
Li, J.J.1
-
53
-
-
0037634342
-
Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage
-
Bianco,N.R. et al. (2003) Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol. Endocrinol., 17, 1344-1355.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1344-1355
-
-
Bianco, N.R.1
-
54
-
-
2942729478
-
Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats
-
Mesia-Vela,S. et al. (2004) Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats. Toxicology, 200, 103-111.
-
(2004)
Toxicology
, vol.200
, pp. 103-111
-
-
Mesia-Vela, S.1
-
55
-
-
0037292971
-
Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies
-
Peter Guengerich,F. et al. (2003) Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies. Mutat. Res., 523-524, 173-182.
-
(2003)
Mutat. Res.
, vol.523-524
, pp. 173-182
-
-
Peter Guengerich, F.1
|