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Volumn 107, Issue 2, 2012, Pages 603-617

Central chemoreceptor modulation of breathing via multipath tuning in medullary ventrolateral respiratory column circuits

Author keywords

Cross correlation; Inspiratory and expiratory neurons; Pre b tzinger complex; Respiratory network; Spike train

Indexed keywords

CARBON DIOXIDE;

EID: 84855365951     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00808.2011     Document Type: Article
Times cited : (15)

References (84)
  • 1
    • 65949119125 scopus 로고    scopus 로고
    • Photostimulation of retrotrapezoid nucleus Phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats
    • Abbott SBG, Stornetta RL, Fortuna MG, Depuy SD, West GH, Harris TE, Guyenet PG. Photostimulation of retrotrapezoid nucleus Phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci 29: 5806-5819, 2009.
    • (2009) J Neurosci , vol.29 , pp. 5806-5819
    • Abbott, S.B.G.1    Stornetta, R.L.2    Fortuna, M.G.3    Depuy, S.D.4    West, G.H.5    Harris, T.E.6    Guyenet, P.G.7
  • 2
    • 0022391859 scopus 로고
    • Evaluation of neuronal connectivity: Sensitivity of cross-correlation
    • Aertsen AM, Gerstein GL. Evaluation of neuronal connectivity: sensitivity of cross-correlation. Brain Res 340: 341-354, 1985.
    • (1985) Brain Res , vol.340 , pp. 341-354
    • Aertsen, A.M.1    Gerstein, G.L.2
  • 3
    • 0024599599 scopus 로고
    • Dynamics of neuronal firing correlation: Modulation of effective connectivity
    • Aertsen AM, Gerstein GL, Habib MK, Palm G. Dynamics of neuronal firing correlation: modulation of "effective connectivity." J Neurophysiol 61: 900-917, 1989.
    • (1989) J Neurophysiol , vol.61 , pp. 900-917
    • Aertsen, A.M.1    Gerstein, G.L.2    Habib, M.K.3    Palm, G.4
  • 5
    • 0023835658 scopus 로고
    • Locations of medullary neurons with nonphasic discharges excited by stimulation of central and/or peripheral chemoreceptors and by activation of nociceptors in cat
    • Arita H, Kogo N, Ichikawa K. Locations of medullary neurons with nonphasic discharges excited by stimulation of central and/or peripheral chemoreceptors and by activation of nociceptors in cat. Brain Res 442: 1-10, 1988a.
    • (1988) Brain Res , vol.442 , pp. 1-10
    • Arita, H.1    Kogo, N.2    Ichikawa, K.3
  • 6
    • 0023946380 scopus 로고
    • Rapid and transient excitation of respiration mediated by central chemoreceptor
    • Arita H, Kogo N, Ichikawa K. Rapid and transient excitation of respiration mediated by central chemoreceptor. J Appl Physiol 64: 1369-1375, 1988b.
    • (1988) J Appl Physiol , vol.64 , pp. 1369-1375
    • Arita, H.1    Kogo, N.2    Ichikawa, K.3
  • 7
    • 0035878643 scopus 로고    scopus 로고
    • Medullary respiratory neurones and control of laryngeal motoneurones during fictive eupnoea and cough in the cat
    • Baekey DM, Morris KF, Gestreau C, Li Z, Lindsey BG, Shannon R. Medullary respiratory neurones and control of laryngeal motoneurones during fictive eupnoea and cough in the cat. J Physiol 534: 565-581, 2001.
    • (2001) J Physiol , vol.534 , pp. 565-581
    • Baekey, D.M.1    Morris, K.F.2    Gestreau, C.3    Li, Z.4    Lindsey, B.G.5    Shannon, R.6
  • 9
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 57: 289-300, 1995.
    • (1995) J R Stat Soc Ser B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 11
    • 0028984595 scopus 로고
    • Central control of breathing in mammals: Neuronal circuitry, membrane properties, and neurotransmitters
    • Bianchi AL, Denavit-Saubie M, Champagnat J. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev 75: 1-45, 1995.
    • (1995) Physiol Rev , vol.75 , pp. 1-45
    • Bianchi, A.L.1    Denavit-Saubie, M.2    Champagnat, J.3
  • 12
    • 77953915875 scopus 로고    scopus 로고
    • Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit
    • Bongianni F, Mutolo D, Cinelli E, Pantaleo T. Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit. Brain Res 1344: 134-147, 2010.
    • (2010) Brain Res , vol.1344 , pp. 134-147
    • Bongianni, F.1    Mutolo, D.2    Cinelli, E.3    Pantaleo, T.4
  • 13
    • 18844482118 scopus 로고    scopus 로고
    • A combined blockade of glycine and calcium-dependent potassium channels abolishes the respiratory rhythm
    • Büsselberg D, Bischoff AM, Richter DW. A combined blockade of glycine and calcium-dependent potassium channels abolishes the respiratory rhythm. Neuroscience 122: 831-841, 2003.
    • (2003) Neuroscience , vol.122 , pp. 831-841
    • Büsselberg, D.1    Bischoff, A.M.2    Richter, D.W.3
  • 14
    • 0015324122 scopus 로고
    • On the regulation of depth and rate of breathing
    • Clark FJ, von Euler C. On the regulation of depth and rate of breathing. J Physiol 222: 267-295, 1972.
    • (1972) J Physiol , vol.222 , pp. 267-295
    • Clark, F.J.1    von Euler, C.2
  • 15
    • 0014262155 scopus 로고
    • Discharge patterns of brain-stem respiratory neurons in relation to carbon dioxide tension
    • Cohen MI. Discharge patterns of brain-stem respiratory neurons in relation to carbon dioxide tension. J Neurophysiol 31: 142-165, 1968.
    • (1968) J Neurophysiol , vol.31 , pp. 142-165
    • Cohen, M.I.1
  • 16
    • 0026610241 scopus 로고
    • Pre-Bötzinger complex in cats: Respiratory neuronal discharge patterns
    • Connelly CA, Dobbins EG, Feldman JL. Pre-Bötzinger complex in cats: respiratory neuronal discharge patterns. Brain Res 590: 337-340, 1992.
    • (1992) Brain Res , vol.590 , pp. 337-340
    • Connelly, C.A.1    Dobbins, E.G.2    Feldman, J.L.3
  • 17
    • 0022461442 scopus 로고
    • Statistical limits for detecting change in the cumulative sum derivative of the peristimulus time histogram
    • Davey NJ, Ellaway PH, Stein RB. Statistical limits for detecting change in the cumulative sum derivative of the peristimulus time histogram. J Neurosci Methods 17: 153-166, 1986.
    • (1986) J Neurosci Methods , vol.17 , pp. 153-166
    • Davey, N.J.1    Ellaway, P.H.2    Stein, R.B.3
  • 18
    • 77956858355 scopus 로고    scopus 로고
    • Patterns of expiratory and inspiratory activation for thoracic motoneurones in the anaesthetized and the decerebrate rat
    • de Almeida ATR, Al-Izki S, Denton ME, Kirkwood PA. Patterns of expiratory and inspiratory activation for thoracic motoneurones in the anaesthetized and the decerebrate rat. J Physiol 588: 2707-2729, 2010.
    • (2010) J Physiol , vol.588 , pp. 2707-2729
    • de Almeida, A.T.R.1    Al-Izki, S.2    Denton, M.E.3    Kirkwood, P.A.4
  • 19
    • 15544366320 scopus 로고    scopus 로고
    • Respiratory action of the intercostal muscles
    • De Troyer A, Kirkwood PA, Wilson TA. Respiratory action of the intercostal muscles. Physiol Rev 85: 717-756, 2005.
    • (2005) Physiol Rev , vol.85 , pp. 717-756
    • de Troyer, A.1    Kirkwood, P.A.2    Wilson, T.A.3
  • 20
    • 0018073914 scopus 로고
    • Cumulative sum technique and its application to the analysis of peristimulus time histograms
    • Ellaway PH. Cumulative sum technique and its application to the analysis of peristimulus time histograms. Electroencephalogr Clin Neurophysiol 45: 302-304, 1978.
    • (1978) Electroencephalogr Clin Neurophysiol , vol.45 , pp. 302-304
    • Ellaway, P.H.1
  • 21
    • 0141641041 scopus 로고    scopus 로고
    • Glycine is used as a transmitter by decrementing expiratory neurons of the ventrolateral medulla in the rat
    • Ezure K, Tanaka I, Kondo M. Glycine is used as a transmitter by decrementing expiratory neurons of the ventrolateral medulla in the rat. J Neurosci 23: 8941-8948, 2003.
    • (2003) J Neurosci , vol.23 , pp. 8941-8948
    • Ezure, K.1    Tanaka, I.2    Kondo, M.3
  • 22
    • 0024457372 scopus 로고
    • Inhibition of inspiratory neurons of the nucleus retroambigualis by expiratory neurons of the Bötzinger complex in the cat
    • Fedorko L, Duffin J, England S. Inhibition of inspiratory neurons of the nucleus retroambigualis by expiratory neurons of the Bötzinger complex in the cat. Exp Neurol 106: 74-77, 1989.
    • (1989) Exp Neurol , vol.106 , pp. 74-77
    • Fedorko, L.1    Duffin, J.2    England, S.3
  • 25
    • 0034047299 scopus 로고    scopus 로고
    • Neuropharmacology of control of respiratory rhythm and pattern in mature mammals
    • Haji A, Takeda R, Okazaki M. Neuropharmacology of control of respiratory rhythm and pattern in mature mammals. Pharmacol Ther 86: 277-304, 2000.
    • (2000) Pharmacol Ther , vol.86 , pp. 277-304
    • Haji, A.1    Takeda, R.2    Okazaki, M.3
  • 26
    • 0029794367 scopus 로고    scopus 로고
    • Respiratory neurons mediating the Breuer-Hering reflex prolongation of expiration in rat
    • Hayashi F, Coles SK, McCrimmon DR. Respiratory neurons mediating the Breuer-Hering reflex prolongation of expiration in rat. J Neurosci 16: 6526-6536, 1996.
    • (1996) J Neurosci , vol.16 , pp. 6526-6536
    • Hayashi, F.1    Coles, S.K.2    McCrimmon, D.R.3
  • 27
    • 0020563054 scopus 로고
    • Respiratory-related hypoglossal nerve activity: Influence of anesthetics
    • Hwang JC, St John WM, Bartlett D. Respiratory-related hypoglossal nerve activity: influence of anesthetics. J Appl Physiol 55: 785-792, 1983.
    • (1983) J Appl Physiol , vol.55 , pp. 785-792
    • Hwang, J.C.1    St John, W.M.2    Bartlett, D.3
  • 28
    • 0031698170 scopus 로고    scopus 로고
    • Control of abdominal muscles
    • Iscoe SD. Control of abdominal muscles. Prog Neurobiol 56: 433-506, 1998.
    • (1998) Prog Neurobiol , vol.56 , pp. 433-506
    • Iscoe, S.D.1
  • 29
    • 0025180513 scopus 로고
    • Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat
    • Jiang C, Lipski J. Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat. Exp Brain Res 81: 639-648, 1990.
    • (1990) Exp Brain Res , vol.81 , pp. 639-648
    • Jiang, C.1    Lipski, J.2
  • 30
    • 0018330594 scopus 로고
    • On the use and interpretation of cross-correlation measurements in the mammalian central nervous system
    • Kirkwood PA. On the use and interpretation of cross-correlation measurements in the mammalian central nervous system. J Neurosci Methods 1: 107-132, 1979.
    • (1979) J Neurosci Methods , vol.1 , pp. 107-132
    • Kirkwood, P.A.1
  • 32
    • 0023067361 scopus 로고
    • Effect of hypercapnic blood injection into the vertebral artery on the phrenic nerve activity in cats
    • Kuwana S, Natsui T. Effect of hypercapnic blood injection into the vertebral artery on the phrenic nerve activity in cats. Jpn J Physiol 37: 155-159, 1987.
    • (1987) Jpn J Physiol , vol.37 , pp. 155-159
    • Kuwana, S.1    Natsui, T.2
  • 33
    • 0032213529 scopus 로고    scopus 로고
    • Medullary raphé neurones and baroreceptor modulation of the respiratory motor pattern in the cat
    • Lindsey BG, Arata A, Morris KF, Hernandez YM, Shannon R. Medullary raphé neurones and baroreceptor modulation of the respiratory motor pattern in the cat. J Physiol 512: 863-882, 1998.
    • (1998) J Physiol , vol.512 , pp. 863-882
    • Lindsey, B.G.1    Arata, A.2    Morris, K.F.3    Hernandez, Y.M.4    Shannon, R.5
  • 34
    • 80053039408 scopus 로고    scopus 로고
    • Central chemoreceptors modulate breathing via multipath tuning in ventrolateral respiratory column circuits
    • Lindsey BG, Ott MM, Nuding SC, Segers LS, O'Connor R, Morris KF. Central chemoreceptors modulate breathing via multipath tuning in ventrolateral respiratory column circuits. FASEB J 25: 847.27, 2011.
    • (2011) FASEB J , vol.25 , Issue.847 , pp. 27
    • Lindsey, B.G.1    Ott, M.M.2    Nuding, S.C.3    Segers, L.S.4    O'Connor, R.5    Morris, K.F.6
  • 35
    • 0024411817 scopus 로고
    • Discharge patterns of rostrolateral medullary expiratory neurons in the cat: Regulation by concurrent network processes
    • Lindsey BG, Segers LS, Shannon R. Discharge patterns of rostrolateral medullary expiratory neurons in the cat: regulation by concurrent network processes. J Neurophysiol 61: 1185-1196, 1989.
    • (1989) J Neurophysiol , vol.61 , pp. 1185-1196
    • Lindsey, B.G.1    Segers, L.S.2    Shannon, R.3
  • 36
    • 0023178903 scopus 로고
    • Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. II. Evidence for inhibitory actions of expiratory neurons
    • Lindsey BG, Segers LS, Shannon R. Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. II. Evidence for inhibitory actions of expiratory neurons. J Neurophysiol 57: 1101-1117, 1987.
    • (1987) J Neurophysiol , vol.57 , pp. 1101-1117
    • Lindsey, B.G.1    Segers, L.S.2    Shannon, R.3
  • 37
    • 58649102927 scopus 로고    scopus 로고
    • Neural circuits controlling diaphragm function in the cat revealed by transneuronal tracing
    • Lois JH, Rice CD, Yates BJ. Neural circuits controlling diaphragm function in the cat revealed by transneuronal tracing. J Appl Physiol 106: 138-152, 2009.
    • (2009) J Appl Physiol , vol.106 , pp. 138-152
    • Lois, J.H.1    Rice, C.D.2    Yates, B.J.3
  • 38
    • 0018196396 scopus 로고
    • Two types of vagal preganglionic motoneurones projecting to the heart and lungs
    • McAllen RM, Spyer KM. Two types of vagal preganglionic motoneurones projecting to the heart and lungs. J Physiol 282: 353-364, 1978.
    • (1978) J Physiol , vol.282 , pp. 353-364
    • McAllen, R.M.1    Spyer, K.M.2
  • 39
    • 0023478805 scopus 로고
    • Detection and estimation of neural connectivity based on crosscorrelation analysis
    • Melssen WJ, Epping WJ. Detection and estimation of neural connectivity based on crosscorrelation analysis. Biol Cybern 57: 403-414, 1987.
    • (1987) Biol Cybern , vol.57 , pp. 403-414
    • Melssen, W.J.1    Epping, W.J.2
  • 40
    • 0021231780 scopus 로고
    • Monosynaptic inhibition of phrenic motoneurons: A long descending projection from Bötzinger neurons
    • Merrill EG, Fedorko L. Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Bötzinger neurons. J Neurosci 4: 2350-2353, 1984.
    • (1984) J Neurosci , vol.4 , pp. 2350-2353
    • Merrill, E.G.1    Fedorko, L.2
  • 42
  • 43
    • 0030041446 scopus 로고    scopus 로고
    • Inspiratory drive and phase duration during carotid chemoreceptor stimulation in the cat: Medullary neurone correlations
    • Morris KF, Arata A, Shannon R, Lindsey BG. Inspiratory drive and phase duration during carotid chemoreceptor stimulation in the cat: medullary neurone correlations. J Physiol 491: 241-259, 1996a.
    • (1996) J Physiol , vol.491 , pp. 241-259
    • Morris, K.F.1    Arata, A.2    Shannon, R.3    Lindsey, B.G.4
  • 44
    • 0030034415 scopus 로고    scopus 로고
    • Long-term facilitation of phrenic nerve activity in cats: Responses and short time scale correlations of medullary neurones
    • Morris KF, Arata A, Shannon R, Lindsey BG. Long-term facilitation of phrenic nerve activity in cats: responses and short time scale correlations of medullary neurones. J Physiol 490: 463-480, 1996b.
    • (1996) J Physiol , vol.490 , pp. 463-480
    • Morris, K.F.1    Arata, A.2    Shannon, R.3    Lindsey, B.G.4
  • 46
    • 1942518928 scopus 로고    scopus 로고
    • Persistent respiratory changes following intermittent hypoxic stimulation in cats and human beings
    • Morris KF, Gozal D. Persistent respiratory changes following intermittent hypoxic stimulation in cats and human beings. Respir Physiol Neurobiol 140: 1-8, 2004.
    • (2004) Respir Physiol Neurobiol , vol.140 , pp. 1-8
    • Morris, K.F.1    Gozal, D.2
  • 48
    • 0035185242 scopus 로고    scopus 로고
    • Central chemosensitivity, sleep, and wakefulness
    • Nattie EE. Central chemosensitivity, sleep, and wakefulness. Respir Physiol 129: 257-268, 2001.
    • (2001) Respir Physiol , vol.129 , pp. 257-268
    • Nattie, E.E.1
  • 49
    • 0029804202 scopus 로고    scopus 로고
    • Central chemoreception in the region of the ventral respiratory group in the rat
    • Nattie EE, Li AI. Central chemoreception in the region of the ventral respiratory group in the rat. J Appl Physiol 81: 1987-1995, 1996.
    • (1996) J Appl Physiol , vol.81 , pp. 1987-1995
    • Nattie, E.E.1    Li, A.I.2
  • 50
    • 0019432208 scopus 로고
    • Erroneous classification of neuronal activity by the respiratory modulation index
    • Netick A, Orem J. Erroneous classification of neuronal activity by the respiratory modulation index. Neurosci Lett 21: 301-306, 1981.
    • (1981) Neurosci Lett , vol.21 , pp. 301-306
    • Netick, A.1    Orem, J.2
  • 52
    • 69949102053 scopus 로고    scopus 로고
    • Central and peripheral chemoreceptors evoke distinct responses in simultaneously recorded neurons of the raphé-pontomedullary respiratory network
    • Nuding SC, Segers LS, Shannon R, O'Connor R, Morris KF, Lindsey BG. Central and peripheral chemoreceptors evoke distinct responses in simultaneously recorded neurons of the raphé-pontomedullary respiratory network. Philos Trans R Soc Lond B Biol Sci 364: 2501-2516, 2009b.
    • (2009) Philos Trans R Soc Lond B Biol Sci , vol.364 , pp. 2501-2516
    • Nuding, S.C.1    Segers, L.S.2    Shannon, R.3    O'Connor, R.4    Morris, K.F.5    Lindsey, B.G.6
  • 53
    • 84855362515 scopus 로고    scopus 로고
    • Open source spike sorting software for large multi-electrode systems. Neuroscience
    • Abstracts. Washington, DC: Society for Neuroscience, 2005, (Online)
    • O'Connor RE, Barnhill PR, Nuding SC, Morris KF, Lindsey BG. Open source spike sorting software for large multi-electrode systems. Neuroscience 2005 Abstracts. Washington, DC: Society for Neuroscience, 2005, Program No. 689.3 (Online).
    • (2005) Program No , vol.3 , pp. 689
    • O'Connor, R.E.1    Barnhill, P.R.2    Nuding, S.C.3    Morris, K.F.4    Lindsey, B.G.5
  • 54
    • 58149393861 scopus 로고    scopus 로고
    • 2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal rat
    • Onimaru H, Ikeda K, Kawakami K. CO2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal rat. J Neurosci 28: 12845-12850, 2008.
    • (2008) J Neurosci , vol.28 , pp. 12845-12850
    • Onimaru, H.1    Ikeda, K.2    Kawakami, K.3
  • 55
    • 0019991399 scopus 로고
    • Characteristics of midbrain respiratory neurons in sleep and wakefulness in the cat
    • Orem J, Netick A. Characteristics of midbrain respiratory neurons in sleep and wakefulness in the cat. Brain Res 244: 231-241, 1982.
    • (1982) Brain Res , vol.244 , pp. 231-241
    • Orem, J.1    Netick, A.2
  • 56
    • 69049105412 scopus 로고    scopus 로고
    • How connectivity, background activity, and synaptic properties shape the cross-correlation between spike trains
    • Ostojic S, Brunel N, Hakim V. How connectivity, background activity, and synaptic properties shape the cross-correlation between spike trains. J Neurosci 29: 10234-10253, 2009.
    • (2009) J Neurosci , vol.29 , pp. 10234-10253
    • Ostojic, S.1    Brunel, N.2    Hakim, V.3
  • 57
    • 84855392764 scopus 로고    scopus 로고
    • Correlational linkage maps of rostral medullary neurons and the ventral respiratory column suggest multiple network sites for motor pattern modulation
    • Abstracts. Washington, DC: Society for Neuroscience, 2008, Program No
    • Ott MM, Nuding SC, Morris KF, Lindsey BG. Correlational linkage maps of rostral medullary neurons and the ventral respiratory column suggest multiple network sites for motor pattern modulation. Neuroscience 2008 Abstracts. Washington, DC: Society for Neuroscience, 2008, Program No. 476.4 (Online).
    • (2008) Neuroscience , vol.4 , Issue.Online , pp. 476
    • Ott, M.M.1    Nuding, S.C.2    Morris, K.F.3    Lindsey, B.G.4
  • 58
    • 79959327616 scopus 로고    scopus 로고
    • Ventrolateral medullary functional connectivity and the respiratory and central chemoreceptor-evoked modulation of retrotrapezoid-parafacial neurons
    • Ott MM, Nuding SC, Segers LS, Lindsey BG, Morris KF. Ventrolateral medullary functional connectivity and the respiratory and central chemoreceptor-evoked modulation of retrotrapezoid-parafacial neurons. J Neurophysiol 105: 2960-2975, 2011.
    • (2011) J Neurophysiol , vol.105 , pp. 2960-2975
    • Ott, M.M.1    Nuding, S.C.2    Segers, L.S.3    Lindsey, B.G.4    Morris, K.F.5
  • 60
    • 0035161123 scopus 로고    scopus 로고
    • Nucleus raphé obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices
    • Peever JH, Necakov A, Duffin J. Nucleus raphé obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices. J Appl Physiol 90: 269-279, 2001.
    • (2001) J Appl Physiol , vol.90 , pp. 269-279
    • Peever, J.H.1    Necakov, A.2    Duffin, J.3
  • 61
    • 0014109171 scopus 로고
    • Neuronal spike trains and stochastic point processes. I. The single spike train
    • Perkel DH, Gerstein GL, Moore GP. Neuronal spike trains and stochastic point processes. I. The single spike train. Biophys J 7: 391-418, 1967a.
    • (1967) Biophys J , vol.7 , pp. 391-418
    • Perkel, D.H.1    Gerstein, G.L.2    Moore, G.P.3
  • 62
    • 0014104894 scopus 로고
    • Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains
    • Perkel DH, Gerstein GL, Moore GP. Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains. Biophys J 7: 419-440, 1967b.
    • (1967) Biophys J , vol.7 , pp. 419-440
    • Perkel, D.H.1    Gerstein, G.L.2    Moore, G.P.3
  • 63
    • 0032548984 scopus 로고    scopus 로고
    • Multiple fragment statistical analysis of postspike effects in spike-triggered averages of rectified EMG
    • Poliakov AV, Schieber MH. Multiple fragment statistical analysis of postspike effects in spike-triggered averages of rectified EMG. J Neurosci Methods 79: 143-150, 1998.
    • (1998) J Neurosci Methods , vol.79 , pp. 143-150
    • Poliakov, A.V.1    Schieber, M.H.2
  • 64
    • 0031596646 scopus 로고    scopus 로고
    • PreBötzinger complex and pacemaker neurons: Hypothesized site and kernel for respiratory rhythm generation
    • Rekling JC, Feldman JL. PreBötzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annu Rev Physiol 60: 385-405, 1998.
    • (1998) Annu Rev Physiol , vol.60 , pp. 385-405
    • Rekling, J.C.1    Feldman, J.L.2
  • 66
    • 0033577685 scopus 로고    scopus 로고
    • Evidence for glycinergic respiratory neurons: Bötzinger neurons express mRNA for glycinergic transporter 2
    • Schreihofer AM, Stornetta RL, Guyenet PG. Evidence for glycinergic respiratory neurons: Bötzinger neurons express mRNA for glycinergic transporter 2. J Comp Neurol 407: 583-597, 1999.
    • (1999) J Comp Neurol , vol.407 , pp. 583-597
    • Schreihofer, A.M.1    Stornetta, R.L.2    Guyenet, P.G.3
  • 68
    • 84855414006 scopus 로고
    • On the relative parts played by nervous and chemical factors in the regulation of respiration
    • Scott FH. On the relative parts played by nervous and chemical factors in the regulation of respiration. J Physiol 37: 301-326, 1908.
    • (1908) J Physiol , vol.37 , pp. 301-326
    • Scott, F.H.1
  • 69
    • 0019941803 scopus 로고
    • Reciprocal tonic activation of inspiratory and expiratory motoneurones by chemical drives
    • Sears TA, Berger AJ, Phillipson EA. Reciprocal tonic activation of inspiratory and expiratory motoneurones by chemical drives. Nature 299: 728-730, 1982.
    • (1982) Nature , vol.299 , pp. 728-730
    • Sears, T.A.1    Berger, A.J.2    Phillipson, E.A.3
  • 71
    • 0023177632 scopus 로고
    • Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. I. Evidence for excitatory and inhibitory actions of inspiratory neurons
    • Segers LS, Shannon R, Saporta S, Lindsey BG. Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. I. Evidence for excitatory and inhibitory actions of inspiratory neurons. J Neurophysiol 57: 1078-1100, 1987.
    • (1987) J Neurophysiol , vol.57 , pp. 1078-1100
    • Segers, L.S.1    Shannon, R.2    Saporta, S.3    Lindsey, B.G.4
  • 72
    • 0034657149 scopus 로고    scopus 로고
    • Functional connectivity among ventrolateral medullary respiratory neurones and responses during fictive cough in the cat
    • Shannon R, Baekey DM, Morris KF, Li Z, Lindsey BG. Functional connectivity among ventrolateral medullary respiratory neurones and responses during fictive cough in the cat. J Physiol 525: 207-224, 2000.
    • (2000) J Physiol , vol.525 , pp. 207-224
    • Shannon, R.1    Baekey, D.M.2    Morris, K.F.3    Li, Z.4    Lindsey, B.G.5
  • 73
    • 0031003530 scopus 로고    scopus 로고
    • Respiratory rhythm generation and synaptic inhibition of expiratory neurons in pre-Bötzinger complex: Differential roles of glycinergic and GABAergic neural transmission
    • Shao XM, Feldman JL. Respiratory rhythm generation and synaptic inhibition of expiratory neurons in pre-Bötzinger complex: differential roles of glycinergic and GABAergic neural transmission. J Neurophysiol 77: 1853- 1860, 1997.
    • (1997) J Neurophysiol 77: 1853- , pp. 1860
    • Shao, X.M.1    Feldman, J.L.2
  • 75
    • 0026360052 scopus 로고
    • Pre-Bötzinger complex: A brainstem region that may generate respiratory rhythm in mammals
    • Smith JC, Ellenberger HH, Ballanyi K, Richter DW, Feldman JL. Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254: 726-729, 1991.
    • (1991) Science , vol.254 , pp. 726-729
    • Smith, J.C.1    Ellenberger, H.H.2    Ballanyi, K.3    Richter, D.W.4    Feldman, J.L.5
  • 77
    • 57749096876 scopus 로고    scopus 로고
    • Lateral parabrachial nucleus mediates shortening of expiration and increase of inspiratory drive during hypercapnia
    • Song G, Poon CS. Lateral parabrachial nucleus mediates shortening of expiration and increase of inspiratory drive during hypercapnia. Respir Physiol Neurobiol 165: 9-12, 2009.
    • (2009) Respir Physiol Neurobiol , vol.165 , pp. 9-12
    • Song, G.1    Poon, C.S.2
  • 78
    • 69949102883 scopus 로고    scopus 로고
    • Chemosensory pathways in the brainstem controlling cardiorespiratory activity
    • Spyer KM, Gourine AV. Chemosensory pathways in the brainstem controlling cardiorespiratory activity. Philos Trans R Soc Lond B Biol Sci 364: 2603-2610, 2009.
    • (2009) Philos Trans R Soc Lond B Biol Sci , vol.364 , pp. 2603-2610
    • Spyer, K.M.1    Gourine, A.V.2
  • 79
    • 53849126814 scopus 로고    scopus 로고
    • Identification of neurotransmitters and co-localization of transmitters in brainstem respiratory neurons
    • Stornetta RL. Identification of neurotransmitters and co-localization of transmitters in brainstem respiratory neurons. Respir Physiol Neurobiol 164: 18-27, 2008.
    • (2008) Respir Physiol Neurobiol , vol.164 , pp. 18-27
    • Stornetta, R.L.1
  • 80
    • 0017349299 scopus 로고
    • Ventilatory response of decorticate and decerebrate cats to hypoxia and CO2
    • Tenney SM, Ou LC. Ventilatory response of decorticate and decerebrate cats to hypoxia and CO2. Respir Physiol 29: 81-92, 1977.
    • (1977) Respir Physiol , vol.29 , pp. 81-92
    • Tenney, S.M.1    Ou, L.C.2
  • 82
    • 0032980799 scopus 로고    scopus 로고
    • Measures of degeneracy and redundancy in biological networks
    • Tononi G, Sporns O, Edelman GM. Measures of degeneracy and redundancy in biological networks. Proc Natl Acad Sci USA 96: 3257-3262, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3257-3262
    • Tononi, G.1    Sporns, O.2    Edelman, G.M.3
  • 83
    • 67649557436 scopus 로고    scopus 로고
    • Glycinergic interneurons are functionally integrated into the inspiratory network of mouse medullary slices
    • Winter S, Fresemann J, Schnell C, Oku Y, Hirrlinger J, Hülsmann S. Glycinergic interneurons are functionally integrated into the inspiratory network of mouse medullary slices. Pflügers Arch 458: 459-469, 2009.
    • (2009) Pflügers Arch , vol.458 , pp. 459-469
    • Winter, S.1    Fresemann, J.2    Schnell, C.3    Oku, Y.4    Hirrlinger, J.5    Hülsmann, S.6


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