Respiratory neurons mediating the Breuer-Hering reflex prolongation of expiration in rat

Journal of Neuroscience

Volumn 16, Issue 20, 1996, Pages 6526-6536

  Hayashi, Fumiaki ^a,b   Coles, Sharon K ^a,c   McCrimmon, Donald R ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CHIBA UNIVERSITY   (Japan)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Breuer Hering reflex; control of breathing; pulmonary stretch receptor; respiratory pattern; vagus nerve; ventral respiratory group

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BREATHING PATTERN; EXCITATORY POSTSYNAPTIC POTENTIAL; HERING BREUER REFLEX; INHIBITORY POSTSYNAPTIC POTENTIAL; LUNG RECEPTOR; MALE; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; VAGUS NERVE;

EID: 0029794367     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-20-06526.1996     Document Type: Article

References (41)

1. Averill DB, Cameron WE, Berger AJ (1984) Monosynaptic excitation of dorsal medullary respiratory neurons by slowly adapting pulmonary stretch receptors. J Neurophysiol 52:771-785.
2. Balis UJ, Morris KF, Koleski J, Lindsey BG (1994) Simulations of a ventrolateral medullary neural network for respiratory rhythmogenesis inferred from spike train cross-correlation. Biol Cybern 70:311-327.
3. Barillot JC, Bianchi AL (1971) Activité des motoneurones laryngés pendant les réflexes de Hering-Breuer. J Physiol (Paris) 63:783-792.
4. Berger AJ (1977) Dorsal respiratory group neurons in the medulla of cat: spinal projections, responses to lung inflation, and superior laryngeal nerve stimulation. Brain Res 135:231-254.
5. Berger AJ, Dick TE (1987) Connectivity of slowly adapting pulmonary stretch receptors with dorsal medullary respiratory neurons. J Neurophysiol 58:1259-1274.
6. Bianchi AL, Barillot JC (1975) Activity of medullary respiratory neurones during reflexes from the lungs in cats. Respir Physiol 25:335-352.
7. Bonham AC, McCrimmon DR (1990) Neurones in a discrete region of the nucleus tractus solitarius required for the Breuer-Hering reflex in rat. J Physiol (Lond) 427:261-280.
8. Bonham AC, Coles SK, McCrimmon DR (1993) Pulmonary stretch receptor afferents activate excitatory amino receptors in the nucleus tractus solitarii in rat. J Physiol (Lond) 464:725-745.
9. Davies RO, Kubin L, Pack AI (1987) Pulmonary stretch receptor relay neurones of the cat: localization and contralateral medullary projections. J Physiol (Lond) 383:571-585.
10. Duffin J, Ezure K, Lipski J (1995) Breathing rhythm generation: focus on the rostral ventrolateral medulla. News Physiol Sci 10:133-140.
11. Ezure K (1990) Synaptic connections between medullary respiratory neurons and considerations on the genesis of respiratory rhythm. Prog Neurobiol 35:429-450.
12. Ezure K, Manabe M (1988) Decrementing expiratory neurons of the Bötzinger complex. II. Direct inhibitory synaptic linkage with ventral respiratory group neurons. Exp Brain Res 72:159-166.
13. Ezure K, Manabe M, Yamada H (1988) Distribution of medullary respiratory neurons in the rat. Brain Res 455:262-270.
14. Feldman JL (1986) Neurophysiology of breathing in mammals. In: Handbook of physiology, Sec 1, The nervous system, Vol 4, Intrinsic regulatory systems of the brain (Bloom FE, ed), pp 463-524. Bethesda, MD: American Physiology Society.
15. Feldman L, Cohen MI (1978) Relation between expiratory duration and rostral medullary expiratory neuronal discharge. Brain Res 141:172-178.
16. Feldman JL, Gautier H (1976) Interaction of pulmonary afferent and pneumotaxic center in control of respiratory pattern in cats. J Neurophysiol 39:31-44.
17. Feldman JL, Speck DF (1983) Interactions among inspiratory neurons in dorsal and ventral respiratory groups in cat medulla. J Neurophysiol 49:472-490.
18. 2 responsiveness of efferent superior laryngeal, hypoglossal, and phrenic activities in anesthetized rats. Jpn J Physiol 32:689-698.
19. Hayashi F, McCrimmon DR (1996) Respiratory motor responses to cranial nerve afferent stimulation in rats. Am J Physiol 271:R1054-R1062.
20. Hayashi F, Coles SK, Behnia R, McCrimmon DR (1991) Vagal input to the ventral respiratory group (VRG) of the rat. Soc Neurosci Abstr 17:200.
21. Jiang C, Lipski J (1990) Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat. Exp Brain Res 81:639-648.
22. Kita H, Armstrong W (1991) A biotin-containing compound N-(2-aminoethyl) biotinamide for intracellular labeling and neuronal tracing studies: comparison with biocytin. J Neurosci Methods 37:141-150.
23. Lindsey BG, Segers LS, Shannon R (1987) Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. II. Evidence for inhibitory actions of expiratory neurons. J Neurophysiol 57:1101-1117.
24. Lipski J (1981) Antidromic activation of neurons as an analytical tool in the study of the central nervous system. J Neurosci Methods 4:1-31.
25. Manabe M, Ezure K (1988) Decrementing expiratory neurons of Bötzinger complex. I. Response to lung inflation and axonal projection. Exp Brain Res 72:150-158.
26. Ogilvie MD, Gottschalk A, Anders K, Richter DW, Pack AI (1992) A network model of respiratory rhythmogenesis. Am J Physiol 32:R962-R975.
27. Oku Y, Tanaka I, Ezure K (1992) Possible inspiratory off-switch neurones in the ventrolateral medulla of the cat. NeuroReport 3:933-936.
28. Pack AI (1981) Sensory inputs to the medulla. Annu Rev Physiol 43:73-90.
29. Parkes MJ, Lara-Muñoz JP, Izzo PN, Spyer KM (1994) Responses of ventral respiratory neurones in the rat to vagus stimulation and the functional division of expiration. J Physiol (Lond) 476:131-139.
30. Quintin L, Gillon JY, Saunier CF, Chouvet G, Chignone M (1989) Continuous volume infusion improves circulatory stability in anesthetized rats. J Neurosci Methods 30:77-83.
31. Remmers JE, Richter DW, Ballantyne D, Bainton CR, Klein JP (1986) Reflex prolongation of stage I of expiration. Pflügers Arch 407:190-198.
32. Richter DW (1982) Generation of maintenance of the respiratory rhythm. J Exp Biol 100:93-107.
33. Richter DW, Ballantyne D, Remmers JE (1986) How is the respiratory rhythm generated? A model. News Physiol Sci 1:109-112.
34. Richter DW, Ballanyi K, Schwarzacher S (1992) Mechanisms of respiratory rhythm generation. Curr Opin Neurobiol 2:788-793.
35. Rossignol S, Lund JP, Drew T (1988) The role of sensory inputs in regulating patterns of rhythmical movements in higher vertebrates. In: Neural control of rhythmic movements in vertebrates (Cohen AH, Rossignol S, Grillner S, eds), pp 201-283. New York: Wiley.
36. Schwarzacher SW, Wilhelm Z, Anders K, Richter DW (1991) The medullary respiratory network in the rat. J Physiol (Lond) 435:631-644.
37. Segers LS, Shannon R, Saporta S, Lindsey BG (1987) Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. I. Evidence for excitatory and inhibitory actions of inspiratory neurons. J Neurophysiol 57:1078-1100.
38. Smith JC, Ellenberger HH, Ballanyi K, Richter DW, Feldman JL (1991a) Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254:726-729.
39. Smith JC, Greer JJ, Liu G, Feldman JL (1991b) Neural mechanisms generating respiratory pattern in mammalian brain stem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity. J Neurophysiol 64:1149-1167.
40. Zheng Y, Barillot JC, Bianchi AL (1991a) Patterns of membrane potentials and distributions of the medullary respiratory neurons in the decerebrate rat. Brain Res 546:261-270.
41. Zheng Y, Barillot JC, Bianchi AL (1991b) Are the post-inspiratory neurons in the decerebrate rat cranial motoneurons or interneurons? Brain Res 551:256-266.