Antiarrhythmic effects of free polyunsaturated fatty acids in an experimental model of LQT2 and LQT3 due to suppression of early afterdepolarizations and reduction of spatial and temporal dispersion of repolarization

Heart Rhythm

Volumn 8, Issue 9, 2011, Pages 1492-1500

  Milberg, Peter ^a   Frommeyer, Gerrit ^a   Kleideite, Anne ^a   Fischer, Alicia ^a   Osada, Nani ^b   Breithardt, Günter ^a   Fehr, Michael ^c   Eckardt, Lars ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

Dispersion of repolarization; Early afterdepolarizations; Long QT syndrome; PUFA; Torsades de pointes

Indexed keywords

DOCOSAHEXAENOIC ACID; ERYTHROMYCIN; ICOSAPENTAENOIC ACID; LINOLENIC ACID; POTASSIUM; VERATRIDINE; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; DISPERSION; EARLY AFTERDEPOLARIZATION; EXPERIMENTAL MODEL; EXPERIMENTAL STUDY; FEMALE; HEART; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; LONG QT SYNDROME; LONG QT2 SYNDROME; LONG QT3 SYNDROME; NONHUMAN; PRIORITY JOURNAL; RABBIT; TORSADE DES POINTES; ANIMAL; DISEASE MODEL; DRUG EFFECT; HEART MUSCLE CONDUCTION SYSTEM; PATHOPHYSIOLOGY;

ALPHA-LINOLENIC ACID; ANIMALS; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; FATTY ACIDS, UNSATURATED; FEMALE; HEART CONDUCTION SYSTEM; LONG QT SYNDROME; RABBITS; TORSADES DE POINTES;

EID: 84855358563     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2011.03.058     Document Type: Article

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