Mammosphere cells from high-passage MCF7 cell line show variable loss of tumorigenicity and radioresistance

Cancer Letters

Volumn 316, Issue 1, 2012, Pages 53-61

  Xie, Guozhu ^a   Zhan, Junfang ^a   Tian, Yunhong ^a   Liu, Ying ^a   Chen, Zhixian ^a   Ren, Chen ^a   Sun, Quanquan ^a   Lian, Jianping ^a   Chen, Longhua ^a   Ruan, Jian ^a   Ye, Changsheng ^a   Sun, Aimin ^a   Yuan, Yawei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Mammosphere cells; Radiation sensitivity; Stem like cancer cells; Tumorigenicity

Indexed keywords

ATM PROTEIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL TRAIT; BREAST CANCER; CANCER CELL; CARCINOGENICITY; CELL ACTIVITY; CELL COMPOSITION; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL LEVEL; CELL LOSS; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFER; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMOSPHERE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION RESPONSE; RADIOSENSITIVITY; X IRRADIATION;

ANTIGENS, CD24; ANTIGENS, CD44; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; G2 PHASE; HUMANS; MUTATION; NEOPLASTIC STEM CELLS; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SPHEROIDS, CELLULAR; TELANGIECTASIS; X-RAYS;

ATAXIA TELANGIECTASIA;

EID: 84855342315     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.10.018     Document Type: Article

References (44)

1. Al-Hajj M., Becker M.W., Wicha M., Weissman I., Clarke M.F. Therapeutic implications of cancer stem cells. Curr. Opin. Genet. Dev. 2004, 14:43-47.
2. Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 2003, 100:3983-3988.
3. Ailles L.E., Weissman I.L. Cancer stem cells in solid tumors. Curr. Opin. Biotechnol. 2007, 18:460-466.
4. Rosen J.M., Jordan C.T. The increasing complexity of the cancer stem cell paradigm. Science 2009, 324:1670-1673.
5. Shackleton M., Quintana E., Fearon E.R., Morrison S.J. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 2009, 138:822-829.
6. Rappa G., Mercapide J., Anzanello F., Prasmickaite L., Xi Y., Ju J., Fodstad O., Lorico A. Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets. Exp. Cell Res. 2008, 314:2110-2122.
7. Ponti D., Costa A., Zaffaroni N., Pratesi G., Petrangolini G., Coradini D., Pilotti S., Pierotti M.A., Daidone M.G. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 2005, 65:5506-5511.
8. Phillips T.M., McBride W.H., Pajonk F. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J. Natl. Cancer Inst. 2006, 98:1777-1785.
9. Briske-Anderson M.J., Finley J.W., Newman S.M. The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells. Proc. Soc. Exp. Biol. Med. 1997, 214:248-257.
10. Chang-Liu C.M., Woloschak G.E. Effect of passage number on cellular response to DNA-damaging agents: cell survival and gene expression. Cancer Lett. 1997, 113:77-86.
11. Yu H., Cook T.J., Sinko P.J. Evidence for diminished functional expression of intestinal transporters in Caco-2 cell monolayers at high passages. Pharm. Res. 1997, 14:757-762.
12. Sambuy Y., De Angelis I., Ranaldi G., Scarino M.L., Stammati A., Zucco F. The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics. Cell Biol. Toxicol. 2005, 21:1-26.
13. Wenger S.L., Senft J.R., Sargent L.M., Bamezai R., Bairwa N., Grant S.G. Comparison of established cell lines at different passages by karyotype and comparative genomic hybridization. Biosci. Rep. 2004, 24:631-639.
14. Osborne C.K., Hobbs K., Trent J.M. Biological differences among MCF-7 human breast cancer cell lines from different laboratories. Breast Cancer Res. Treat. 1987, 9:111-121.
15. Page M.J., Field J.K., Everett N.P., Green C.D. Serum regulation of the estrogen responsiveness of the human breast cancer cell line MCF-7. Cancer Res. 1983, 43:1244-1250.
16. Lippman M., Bolan G., Huff K. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res. 1976, 36:4595-4601.
17. Reddel R.R., Murphy L.C., Hall R.E., Sutherland R.L. Differential sensitivity of human breast cancer cell lines to the growth-inhibitory effects of tamoxifen. Cancer Res. 1985, 45:1525-1531.
18. Graham K.A., Richardson C.L., Minden M.D., Trent J.M., Buick R.N. Varying degrees of amplification of the N-ras oncogene in the human breast cancer cell line MCF-7. Cancer Res. 1985, 45:2201-2205.
19. Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., Wicha M.S. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003, 17:1253-1270.
20. Prevo R., Deutsch E., Sampson O., Diplexcito J., Cengel K., Harper J., O'Neill P., McKenna W.G., Patel S., Bernhard E.J. Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity. Cancer Res. 2008, 68:5915-5923.
21. Imrich A., Kobzik L. Flow cytometric analysis of macrophage oxidative metabolism using DCFH. Methods Mol. Biol. 1998, 91:97-108.
22. Wollman R., Yahalom J., Maxy R., Pinto J., Fuks Z. Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro. Int. J. Radiat. Oncol. Biol. Phys. 1994, 30:91-98.
23. Paris F., Fuks Z., Kang A., Capodieci P., Juan G., Ehleiter D., Haimovitz-Friedman A., Cordon-Cardo C., Kolesnick R. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001, 293:293-297.
24. Smith J., Ladi E., Mayer-Proschel M., Noble M. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell. Proc. Natl. Acad. Sci. USA 2000, 97:10032-10037.
25. Ito K., Hirao A., Arai F., Matsuoka S., Takubo K., Hamaguchi I., Nomiyama K., Hosokawa K., Sakurada K., Nakagata N., Ikeda Y., Mak T.W., Suda T. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004, 431:997-1002.
26. Tsatmali M., Walcott E.C., Crossin K.L. Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors. Brain Res. 2005, 1040:137-150.
27. Tothova Z., Kollipara R., Huntly B.J., Lee B.H., Castrillon D.H., Cullen D.E., McDowell E.P., Lazo-Kallanian S., Williams I.R., Sears C., Armstrong S.A., Passegue E., DePinho R.A., Gilliland D.G. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 2007, 128:325-339.
28. Miyamoto K., Araki K.Y., Naka K., Arai F., Takubo K., Yamazaki S., Matsuoka S., Miyamoto T., Ito K., Ohmura M., Chen C., Hosokawa K., Nakauchi H., Nakayama K., Nakayama K.I., Harada M., Motoyama N., Suda T., Hirao A. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 2007, 1:101-112.
29. Diehn M., Cho R.W., Lobo N.A., Kalisky T., Dorie M.J., Kulp A.N., Qian D., Lam J.S., Ailles L.E., Wong M., Joshua B., Kaplan M.J., Wapnir I., Dirbas F.M., Somlo G., Garberoglio C., Paz B., Shen J., Lau S.K., Quake S.R., Brown J.M., Weissman I.L., Clarke M.F. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009, 458:780-783.
30. Ito K., Takubo K., Arai F., Satoh H., Matsuoka S., Ohmura M., Naka K., Azuma M., Miyamoto K., Hosokawa K., Ikeda Y., Mak T.W., Suda T., Hirao A. Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J. Immunol. 2007, 178:103-110.
31. Yalcin S., Zhang X., Luciano J.P., Mungamuri S.K., Marinkovic D., Vercherat C., Sarkar A., Grisotto M., Taneja R., Ghaffari S. Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J. Biol. Chem. 2008, 283:25692-25705.
32. Momcilovic O., Choi S., Varum S., Bakkenist C., Schatten G., Navara C. Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. Stem Cells 2009, 27:1822-1835.
33. - phenotype is enriched in basal-like breast tumors. Breast Cancer Res. 2008, 10:R53.
34. Ginestier C., Hur M.H., Charafe-Jauffret E., Monville F., Dutcher J., Brown M., Jacquemier J., Viens P., Kleer C.G., Liu S., Schott A., Hayes D., Birnbaum D., Wicha M.S., Dontu G. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007, 1:555-567.
35. Fillmore C.M., Kuperwasser C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res. 2008, 10:R25.
36. Powell S., McMillan T.J. DNA damage and repair following treatment with ionizing radiation. Radiother. Oncol. 1990, 19:95-108.
37. Ward J.F. Biochemistry of DNA lesions. Radiat. Res. Suppl. 1985, 8:S103-111.
38. Tamamoto T., Ohnishi K., Takahashi A., Wang X., Yosimura H., Ohishi H., Uchida H., Ohnishi T. Correlation between gamma-ray-induced G2 arrest and radioresistance in two human cancer cells. Int. J. Radiat. Oncol. Biol. Phys. 1999, 44:905-909.
39. Teyssier F., Bay J.O., Dionet C., Verrelle P. [Cell cycle regulation after exposure to ionizing radiation]. Bull. Cancer 1999, 86:345-357.
40. Bernhard E.J., McKenna W.G., Muschel R.J. Cyclin expression and G2-phase delay after irradiation. Radiat. Res. 1994, 138:S64-S67.
41. Warenius H.M., Jones M.D., Thompson C.C. Exit from G2 phase after 2 Gy gamma irradiation is faster in radiosensitive human cells with high expression of the RAF1 proto-oncogene. Radiat. Res. 1996, 146:485-493.
42. Raju U., Nakata E., Yang P., Newman R.A., Ang K.K., Milas L. In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations. Int. J. Radiat. Oncol. Biol. Phys. 2002, 54:886-894.
43. Elkind M.M. Fractional dose radiotherapy and its relationship to survival curve shape. Cancer Treat. Rev. 1976, 3:1-15.
44. Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.