Preventive effect of Teucrium polium on learning and memory deficits in diabetic rats

Medical Science Monitor

Volumn 18, Issue 1, 2012, Pages

  Hasanein, Parisa ^a   Shahidi, Siamak ^b  

^a BU ALI SINA UNIVERSITY   (Iran)

^b HAMADAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Diabetes mellitus; Learning; Memory; Rats; Teucrium polium

Indexed keywords

GLUCOSE; TEUCRIUM POLIUM EXTRACT;

AMNESIA; ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GLUCOSE MONITORING; BLOOD SAMPLING; BODY WEIGHT; COGNITION; CONTROLLED STUDY; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; LEARNING; LEARNING DISORDER; MALE; MEMORY; MENTAL PERFORMANCE; NONHUMAN; PASSIVE AVOIDANCE LEARNING TEST; RAT; RETENTION TEST; STREPTOZOCIN DIABETES;

EID: 84855293905     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.882201     Document Type: Article

References (43)

1. Gispen WH, Biessels GJ: Cognition and synaptic plasticity in diabetes mellitus. Trends in Neurosci, 2000; 23: 542-49
2. McCall AL: The impact of diabetes on the CNS. Diabetes, 1992; 41: 557-70
3. Artola A, Kamal A, Ramakers GM et al: Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus. Eur J Neurosci, 2005; 22: 169-78
4. Kucukatay V, Ǎar A, Gumuslu S et al: Effect of sulfur dioxide on active and passive avoidance in experimental diabetes mellitus: Relation to oxidant stress and antioxidant enzymes. Int J Neurosci, 2007; 117: 1091-107
5. Kucukatay V, Hacioǧlu G, Ozkaya G et al: The effect of diabetes mellitus on active avoidance learning in rats: the role of nitric oxide. Med Sci Monit, 2009; 15(3): BR88-93
6. Reaven GM, Thompson LW, Nahum D et al: Relationship between hyperglycemia and cognitive function in older NIDDM patients. Diabetes Care, 1990; 13: 16-21
7. Ryan CM: Neurobehavioral complications of type I diabetes. Examination of possible risk factors. Diabetes Care, 1988; 11: 86-93
8. Tun PA, Nathan DM, Perlmuter LC: Cognitive and affective disorders in elderly diabetics. Clin Geriatr Med, 1990; 6: 731-46
9. Baydas G, Nedzvetskii VS, Nerush PA et al: Altered expression of NCAM in hippocampus and cortex may underlie memory and learning deficits in rats with streptozotocin-induced diabetes mellitus. Life Sci, 2003; 73: 1907-16
10. Lupien SB, Bluhm EJ, Ishii DN: Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. J Neurosci Res, 2003; 74: 512-23
11. Patil CS, Singh VP, Kulkarni SK: Modulatory effect of sildenafil in diabetes and electroconvulsive shock-induced cognitive dysfunction in rats. Pharmacol Rep, 2006; 58: 373-80
12. Tuzcu M, Baydas G: Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur J Pharmacol, 2006; 537: 106-10
13. Craig WJ: Health-promoting properties of common herbs. Am J Clin Nutr, 1999; 70: S491-99
14. Hasani-Ranjbar S, Nayebi N, Larijani B et al: A systematic review of the efficacy and safety of Teucrium species; From anti-oxidant to antidiabetic effects. Int J Pharmacol, 2010; 6: 315-25
15. Howes MJR, Perry NSL, Houghton PJ: Plants with traditional uses and activities relevant to the management of Alzheimer's disease and other cognitive disorders. Phytother Res, 2003; 17: 1-18
16. Perry N, Court G, Bidet N et al: Cholinergic activities of European herbs and potential for dementia therapy. J Geriatr Psychiatry, 1996; 11: 1063-69
17. Tuncer H: Utilization of Wild Plants as Medicine, Vol. II. In: The Ministry of Food and Agriculture eds. 1978, Ankara, Atak Printhouse
18. Orhan I, Aslan M: Appraisal of scopolamine-induced antiamnesic effect in mice and in vitro antiacetylcholinesterase and antioxidant activities of some traditionally used Lamiaceae plants. J Ethnopharmacol, 2009; 122: 327-32
19. Abdolghaffari AH, Baghaei A, Moayer F et al: On the benefit of Teucrium in murine colitis through improvement of toxic inflammatory mediators. Hum Exp Toxicol, 2010; 29: 287-95
20. Baluchnejadmojarad T, Roghani M, Roghani-Dehkordi F: Antinociceptive effect of Teucrium polium leaf extract in the diabetic rat formalin test. J Ethnopharmacol, 2005; 97: 207-10
21. Hasani P, Yasa N, Vosough-Ghanbari S et al: In vivo antioxidant potential of Teucrium polium, as compared to alpha-tocopherol. Acta Pharm, 2007; 57: 123-29
22. Lashgari R, Motamedi F, Zahedi Asl S et al: Behavioral and electrophysiological studies of chronic oral administration of L-type calcium channel blocker verapamil on learning and memory in rats. Behav Brain Res, 2006; 171: 324-28
23. Shahidi S, Motamedi F, Bakeshloo SA et al: The effect of reversible inactivation of the supramammillary nucleus on passive avoidance learning in rats. Behav Brain Res, 2004; 152: 81-87
24. Shahidi S, Komaki A, Mahmoodi M et al: Ascorbic acid supplementation could affect passive avoidance learning and memory in rat. Brain Res Bull, 2008; 76: 109-13
25. Hasani-Ranjbar S, Larijani B, Abdollahi M: A systematic review of Iranian medicinal plants useful in diabetes mellitus. Arch Med Sci, 2008; 3: 285-92
26. Hasani-Ranjbar S, Larijani B, Abdollahi M: A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases. Inflamm Allergy Drug Targets, 2009; 8: 2-10
27. Abdollahi M, Karimpour H, Monsef-Esfehani HR: Antinociceptive effects of Teucrium polium L total extract and essential oil in mouse writhing test. Pharmacol Res, 2003; 48: 31-35
28. Kadifkova-Panovska T, Kulevanova S, Stefova M: In vitro antioxidant activity of some Teucrium species (Lamiaceae). Acta Pharm, 2005; 55: 207-14
29. Ljubuncic P, Azaizeh H, Portnaya I et al: Antioxidant activity and cytotoxicity of eight plants used in traditional Arab medicine in Israel. J Ethnopharmacol, 2005; 99: 43-47
30. Suboh SM, Bilto YY, Aburjai TA: Protective effects of selected medicinal plants against protein degradation, lipid peroxidation and deformability loss of oxidatively stressed human erythrocytes. Phytother Res, 2004; 18: 280-84
31. Proestos C, Sereli D, Komaitis M: Determination of phenolic compounds in aromatic plants by RP-HPLC and GC-MS. Food Chem, 2006; 95: 44-52
32. Tiwari V, Kuhad A, Bishnoi M et al: Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats. Pharmacol Biochem Behav, 2009; 93: 183-89
33. Rahimi R, Nikfar S, Larijani B et al: A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother, 2005; 59: 365-73
34. Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes, 1991; 40: 405-12
35. Kakkar R, Kalra J, Mantha S et al: Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol Cell Biochem, 1995; 151: 113-19
36. Blokland A, Jolles J: Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin. Pharmacol Biochem Behav, 1993; 44: 491-94
37. Sharma M, Gupta YK: Effect of chronic treatment of melatonin on learning, memory and oxidative deficiencies induced by intracerebro-ventricular streptozotocin in rats. Pharmacol Biochem Behav, 2001a; 70: 325-31
38. Sharma M, Gupta YK: Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sci, 2001b; 68: 1021-29
39. Sonkusare S, Srinivasan K, Kaul C et al: Effect of donepezil and lercanidipine on memory impairment induced by intracerebroventricular streptozotocin in rats. Life Sci, 2005; 77: 1-14
40. Biessels GJ, Kerssen A, de Haan EH et al: Cognitive dysfunction and diabetes: Implications for primary care. Prim Care Diabetes, 2007; 1: 187-93
41. Gharaibeh MN, Elayan HH, Salhab AS: Hypoglycemic effects of Teucrium polium. J Ethnopharmacol, 1988; 24: 93-99
42. Shahraki MR, Arab MR, Mirimokaddam E et al: The effect of Teucrium polium (Calpoureh) on liver function, serum lipids and glucose in diabetic male rats. Iran Biomed J, 2007; 11: 65-68
43. Weeks BS: Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Med Sci Monit, 2009;15(11): RA256-62