Ceramide generation and apoptosis in autoimmunity

Clinical and Applied Immunology Reviews

Volumn 1, Issue 3-4, 2001, Pages 173-179

  Goldkorn, Tzipora ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Autoimmune diseases; Ceramide

Indexed keywords

APOLIPOPROTEIN E; BETA2 GLYCOPROTEIN 1; CERAMIDE; FAS ANTIGEN; HLA ANTIGEN CLASS 1; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID ANTIBODY; PROTEIN BCL 2; SPHINGOMYELIN;

APOPTOSIS; ASTHMA; ATHEROSCLEROSIS; AUTOIMMUNE DISEASE; CELL ACTIVATION; CELL DEATH; CELL STRUCTURE; CYSTIC FIBROSIS; EX VIVO STUDY; GENETIC CODE; HUMAN; IMMUNE RESPONSE; INFLAMMATION; INTRACELLULAR SPACE; LIPID METABOLISM; NONHUMAN; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TISSUE INJURY;

EID: 3142587410     PISSN: 15291049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1529-1049(01)00011-3     Document Type: Review

References (52)

1. T. Goldkorn K.A. Dressler J. Muindi N.S. Radin J. Mendelsohn D. Menaldino D. Liotta R.N. Kolesnick Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action J Biol Chem 266 24 1991 16092-16097
2. L.M. Obeid C.M. Linardic L.A. Karolak Y.A. Hannun Programmed cell death induced by ceramide Science 259 5102 1993 1769-1771
3. G.S. Dbaibo L.M. Obeid Y.A. Hannun Tumor necrosis factor-alpha [TNF-alpha] signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B J Biol Chem 268 24 1993 17762-17766
4. N. Andrieu R. Salvayre J.P. Jaffrezou T. Levade Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation J Biol Chem 270 41 1995 24518-24524
5. M.Y. Kim C. Linardic L. Obeid Y. Hannun Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation J Biol Chem 266 1 1991 484-489
6. M.G. Cifone R. De Maria P. Roncaioli M.R. Rippo M. Azuma L.L. Lanier A. Santoni R. Testi Apoptotic signaling through CD95 [Fas/Apo-1] activates an acidic sphingomyelinase J Exp Med 180 4 1994 1547-1552
7. C.G. Tepper S. Jayadev B. Liu A. Bielawska R. Wolff S. Yonehara Y.A. Hannun M.F. Seldin Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity Proc Natl Acad Sci USA 92 18 1995 8443-8447
8. S.J. Martin D.D. Newmeyer S. Mathias D.M. Farschon H.G. Wang J.C. Reed R.N. Kolesnick D.R. Green Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis Embo J 14 21 1995 5191-5200
9. L.M. Boucher K. Wiegmann A. Futterer K. Pfeffer T. Machleidt S. Schutze T.W. Mak M. Kronke CD28 signals through acidic sphingomyelinase J Exp Med 181 6 1995 2059-2068
10. Y.A. Hannun Functions of ceramide in coordinating cellular responses to stress Science 274 5294 1996 1855-1859
11. M. Verheij R. Bose X.H. Lin B. Yao W.D. Jarvis S. Grant M.J. Birrer E. Szabo L.I. Zon J.M. Kyriakis A. Haimovitz-Friedman Z. Fuks R.N. Kolesnick Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis Nature 380 6569 1996 75-79
12. P. Santana L.A. Pena A. Haimovitz-Friedman S. Martin D. Green M. McLoughlin C. Cordon-Cardo E.H. Schuchman Z. Fuks R. Kolesnick Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis Cell 86 2 1996 189-199
13. J.P. Jaffrezou T. Levade A. Bettaieb N. Andrieu C. Bezombes N. Maestre S. Vermeersch A. Rousse G. Laurent Daunorubicin-induced apoptosis triggering of ceramide generation through sphingomyelin hydrolysis Embo J 15 10 1996 2417-2424
14. T. Goldkorn N. Balaban M. Shannon V. Chea K. Matsukuma D. Gilchrist H. Wang C. Chan H2O2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells J Cell Sci 111 Pt 21 1998 3209-3220
15. C. Chan T. Goldkorn Ceramide path in human lung cell death Am J Respir Cell Mol Biol 22 4 2000 460-468
16. Lavrentiadou S, Chan C, Rasooly R, van der Vliet A, Kawcak T, Goldkorn T. Ceramide path in lung epithelial cells is regulated by glutathione. Submitted 2000.
17. J.P. Jaffrezou N. Maestre V. de Mas-Mansat C. Bezombes T. Levade G. Laurent Positive feedback control of neutral sphingomyelinase activity by ceramide Faseb J 12 11 1998 999-1006
18. Merrill Jr AH, Jones DD. An update of the enzymology and regulation of sphingomyelin metabolism Biochim Biophys Acta 1044 1 1990 1-12
19. K. Wiegmann S. Schutze T. Machleidt D. Witte M. Kronke Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling Cell 78 6 1994 1005-1015
20. A. Ashkenazi V.M. Dixit Death receptors signaling and modulation Science 281 5381 1998 1305-1308
21. R. Schwandner K. Wiegmann K. Bernardo D. Kreder M. Kronke TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase J Biol Chem 273 10 1998 5916-5922
22. K. Wiegmann R. Schwandner O. Krut W.C. Yeh T.W. Mak M. Kronke Requirement of FADD for tumor necrosis factor-induced activation of acid sphingomyelinase J Biol Chem 274 9 1999 5267-5270
23. S. Adam-Klages R. Schwandner D. Adam D. Kreder K. Bernardo M. Kronke Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor J Leukoc Biol 63 6 1998 678-682
24. S. Mathias L.A. Pena R.N. Kolesnick Signal transduction of stress via ceramide Biochem. J. 335 1998 465-480
25. B.B. Wolf D.R. Green Suicidal tendencies apoptotic cell death by caspase family proteinases J Biol Chem 274 29 1999 20049-20052
26. M.J. Smyth D.K. Perry J. Zhang G.G. Poirier Y.A. Hannun L.M. Obeid prICE a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2 Biochem J 316 Pt 1 1996 25-28
27. G.S. Dbaibo D.K. Perry C.J. Gamard R. Platt G.G. Poirier L.M. Obeid Y.A. Hannun Cytokine response modifier A [CrmA] inhibits ceramide formation in response to tumor necrosis factor [TNF]-alpha CrmA and Bcl-2 target distinct components in the apoptotic pathway J Exp Med 185 3 1997 481-490
28. W. El-Assaad M. El-Sabban C. Awaraji N. Abboushi G.S. Dbaibo Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis Biochem J 336 Pt 3 1998 735-741
29. Y.A. Hannun C. Luberto Ceramide in the eukaryotic stress response Trends Cell Biol 10 2 2000 73-80
30. N. Mizushima H. Kohsaka N. Miyasaka Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells Ann Rheum Dis 57 8 1998 495-499
31. K. Hayashida Y. Shimaoka T. Ochi P.E. Lipsky Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism J Immunol 164 2 2000 1110-1116
32. Y. Ichinose K. Eguchi K. Migita Y. Kawabe T. Tsukada T. Koji K. Abe T. Aoyagi H. Nakamura S. Nagataki Apoptosis induction in synovial fibroblasts by ceramide in vitro and in vivo effects J Lab Clin Med 131 5 1998 410-416
33. C. Miret J. Font R. Molina M. Garcia-Carrasco X. Filella M. Ramos R. Cervera A. Ballesta M. Ingelmo Bcl-2 oncogene [B cell lymphoma/ leukemia-2] levels correlate with systemic lupus erythematosus disease activity Anticancer Res 19 4B 1999 3073-3076
34. R. Caricchio P.L. Cohen Spontaneous and induced apoptosis in systemic lupus erythematosus multiple assays fail to reveal consistent abnormalities Cell Immunol 198 1 1999 54-60
35. M. Salmon C. Gordon The role of apoptosis in systemic lupus erythematosus Rheumatology 38 12 1999 1177-1183
36. K. Sakata A. Sakata N. Vela-Roch R. Espinosa A. Escalante L. Kong T. Nakabayashi J. Cheng N. Talal H. Dang Fas [CD95]-transduced signal preferentially stimulates lupus peripheral T lymphocytes Eur J Immunol 28 9 1998 2648-2660
37. W.E. Stehbens The significance of programmed cell death or apoptosis and matrix vesicles in atherogenesis Cell Mol Biol 46 1 2000 99-110
38. M.M. Kockx A.G. Herman Apoptosis in atherosclerosis beneficial or detrimental? Cardiovasc Res 45 3 2000 736-746
39. M.M. Kockx M.W. Knaapen The role of apoptosis in vascular disease J Pathol 190 3 2000 267-280
40. E. DiMango A.J. Ratner R. Bryan S. Tabibi A. Prince Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells J Clin Invest 101 11 1998 2598-2605
41. S. Jayaraman M. Castro M. O'Sullivan M.J. Bragdon M.J. Holtzman Resistance to Fas-mediated T cell apoptosis in asthma J Immunol 162 3 1999 1717-1722
42. L. Genestier A.F. Prigent R. Paillot L. Quemeneur I. Durand J. Banchereau J.P. Revillard N.J. Bonnefoy-Berard Caspase-dependent ceramide production in Fas- and HLA class I-mediated peripheral T cell apoptosis J Biol Chem 273 9 1998 5060-5066
43. M. Harada-Shiba M. Kinoshita H. Kamido K. Shimokado Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms J Biol Chem 273 16 1998 9681-9687
44. Lavrentiadou S, George J, Gilburd B, Harats D, Shoenfeld Y, Barak A, Goldkorn T. OxLDL induces ceramide and apoptosis in macrophages but not in aortas of ApoE-deficient mice. 6th Annual Meeting of the Oxygen Society. Free Radical Biology & Medicine 1999;27(Suppl 1):S114.
45. S. Visvanathan H.P. McNeil Cellular immunity to beta 2-glycoprotein-1 in patients with the antiphospholipid syndrome J Immunol 162 11 1999 6919-6925
46. J. George A. Afek B. Gilburd M. Blank Y. Levy A. Aron-Maor H. Levkovitz A. Shaish I. Goldberg J. Kopolovic D. Harats Y. Shoenfeld Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I Circulation 98 11 1998 1108-1115
47. V. Pittoni C.T. Ravirajan S. Donohoe S.J. MacHin P.M. Lydyard D.A. Isenberg Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and beta2-glycoprotein I [beta2-GPI] on apoptotic cells Clin Exp Immunol 119 3 2000 533-543
48. J. George D. Harats B. Gilburd A. Afek Y. Levy J. Schneiderman I. Barshack J. Kopolovic Y. Shoenfeld Immunolocalization of beta2-glycoprotein I [apolipoprotein H] to human atherosclerotic plaques potential implications for lesion progression Circulation 99 17 1999 2227-2230
49. J. George Y. Shoenfeld D. Harats The involvement of beta2-glycoprotein I in human and murine atherosclerosis J Autoimmun 13 1 1999 57-60
50. A. Afek J. George Y. Shoenfeld B. Gilburd Y. Levy A. Shaish P. Keren Z. Janackovic I. Goldberg J. Kopolovic D. Harats Enhancement of atherosclerosis in beta-2-glycoprotein I-immunized apolipoprotein E-deficient mice Pathobiology 67 1 1999 19-25
51. T. Levade J.P. Jaffrezou Signaling sphingomyelinases which, where, how and why? Biochim Biophys Acta 1438 1999 1-17
52. K. Hofmann V.M. Dixit Ceramide in apoptosis-does it really matter? Trends Biochem Sci 23 10 1998 374-377