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Volumn 12, Issue 4, 2011, Pages 295-305

Up-regulation of metallothionein gene expression in Parkinsonian astrocytes

Author keywords

Cell death; Glial degeneration; Megalin; Neuroprotection; Reactive astrocytes

Indexed keywords

MEGALIN; METALLOTHIONEIN;

EID: 84855289046     PISSN: 13646745     EISSN: 13646753     Source Type: Journal    
DOI: 10.1007/s10048-011-0294-5     Document Type: Article
Times cited : (57)

References (68)
  • 1
    • 0032738677 scopus 로고    scopus 로고
    • The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
    • Mirza B, Hadberg H, Thomsen P, Moos T (2000) The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience 95:425-432
    • (2000) Neuroscience , vol.95 , pp. 425-432
    • Mirza, B.1    Hadberg, H.2    Thomsen, P.3    Moos, T.4
  • 4
    • 77950346796 scopus 로고    scopus 로고
    • Ontogenesis and migration of metallothionein I/II-containing glial cells in the human telencephalon during the second trimester
    • Cozzi B, Giacomello M, Zambenedetti P, Bolognin S, Rossipal E, Peruffo A, Zatta P (2010) Ontogenesis and migration of metallothionein I/II-containing glial cells in the human telencephalon during the second trimester. Brain Res 1327:16-23
    • (2010) Brain Res , vol.1327 , pp. 16-23
    • Cozzi, B.1    Giacomello, M.2    Zambenedetti, P.3    Bolognin, S.4    Rossipal, E.5    Peruffo, A.6    Zatta, P.7
  • 5
    • 80755132177 scopus 로고    scopus 로고
    • Metallothionein protein evolution: A miniassay
    • doi:10.1007/s00775-011-0798-3
    • Capdevila M, Atrian S (2011) Metallothionein protein evolution: a miniassay. J Biol Inorg Chem. doi:10.1007/s00775-011-0798-3
    • (2011) J Biol Inorg Chem
    • Capdevila, M.1    Atrian, S.2
  • 6
    • 52649122792 scopus 로고    scopus 로고
    • The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS
    • Hozumi I, Yamada M, Uchida Y, Ozawa K, Takahashi H, Inuzuka T (2008) The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS. Amyotroph Lateral Scler 9:294-298
    • (2008) Amyotroph Lateral Scler , vol.9 , pp. 294-298
    • Hozumi, I.1    Yamada, M.2    Uchida, Y.3    Ozawa, K.4    Takahashi, H.5    Inuzuka, T.6
  • 7
    • 0037996720 scopus 로고    scopus 로고
    • Metallothionein-IIA promotes initial neurite elongation and postinjury reactive neurite growth and facilitates healing after focal cortical brain injury
    • Chung RS, Vickers JC, Chuah MI, West AK (2003) Metallothionein-IIA promotes initial neurite elongation and post-injury reactive neurite growth and facilitates healing after focal cortical brain injury. J Neurosci 23:3336-3342 (Pubitemid 36531975)
    • (2003) Journal of Neuroscience , vol.23 , Issue.8 , pp. 3336-3342
    • Chung, R.S.1    Vickers, J.C.2    Chuah, M.I.3    West, A.K.4
  • 8
    • 34948859040 scopus 로고    scopus 로고
    • Protective effects of metallothionein against dopamine quinone-induced dopaminergic neurotoxicity
    • DOI 10.1016/j.febslet.2007.09.046, PII S0014579307010289
    • Miyazaki I, Asanuma M, Hozumi H, Miyoshi S (2007) Protective effects of metallothionein against dopamine quinone-induced dopaminergic neurotoxicity. FEBS Lett 581:5003-5008 (Pubitemid 47531776)
    • (2007) FEBS Letters , vol.581 , Issue.25 , pp. 5003-5008
    • Miyazaki, I.1    Asanuma, M.2    Hozumi, H.3    Miyoshi, K.4    Sogawa, N.5
  • 11
    • 33750600258 scopus 로고    scopus 로고
    • Novel roles for metallothionein-I + II (MT-I + II) in defense responses, neurogenesis, and tissue restoration after traumatic brain injury: Insights from global gene expression profiling in wild-type and MT-I + II knockout mice
    • DOI 10.1002/jnr.21043
    • Penkowa M, Cáceres M, Borup R, Nielsen FC, Poulsen CB, Quintana A, Molinero A, Carrasco J, Florit S, Giralt M, Hidalgo J (2006) Novel roles for metallothionein-I+II (MT-I+II) in defenseresponses, neurogenesis, and tissue restoration after traumatic brain injury: insights from global gene expression profiling in wild-type and MT-I+II knockout mice. J Neurosci Res 84:1452-1474 (Pubitemid 44683139)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.7 , pp. 1452-1474
    • Penkowa, M.1    Caceres, M.2    Borup, R.3    Nielsen, F.C.4    Poulsen, C.B.5    Quintana, A.6    Molinero, A.7    Carrasco, J.8    Florit, S.9    Giralt, M.10    Hidalgo, J.11
  • 12
    • 27944450105 scopus 로고    scopus 로고
    • Extensive cortico-subcortical lesions in Wilson's disease: Clinico-pathological study of two cases
    • DOI 10.1007/s00401-005-1061-1
    • Mikol J, Vital C, Wassef M, Chappuis P, Poupon J, Lecharpentier M, Woimant F (2005) Extensive cortico-subcortical lesions in Wilson's disease: clinico-pathological study of two cases. Acta Neuropathol 110:451-458 (Pubitemid 41672338)
    • (2005) Acta Neuropathologica , vol.110 , Issue.5 , pp. 451-458
    • Mikol, J.1    Vital, C.2    Wassef, M.3    Chappuis, P.4    Poupon, J.5    Lecharpentier, M.6    Woimant, F.7
  • 13
    • 77957338177 scopus 로고    scopus 로고
    • Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration
    • Wunderlich K, Leveillard T, Penkowa M, Zrenner E, Perez M (2010) Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration. Investig Ophthalmol Vis Sci 51:4809-4820
    • (2010) Investig Ophthalmol Vis Sci , vol.51 , pp. 4809-4820
    • Wunderlich, K.1    Leveillard, T.2    Penkowa, M.3    Zrenner, E.4    Perez, M.5
  • 14
    • 80755140125 scopus 로고    scopus 로고
    • Chemistry and biology of mammalian metallothioneins
    • doi:10.1007/s00775-011-0799-2
    • Vašák M, Meloni G (2011) Chemistry and biology of mammalian metallothioneins. J Biol Inorg Chem. doi:10.1007/s00775-011-0799-2
    • (2011) J Biol Inorg Chem
    • Vašák, M.1    Meloni, G.2
  • 17
    • 77954359335 scopus 로고    scopus 로고
    • Metallothionein-3 regulates lysosomal function in cultured astrocytes under both normal and oxidative conditions
    • Lee S, Park M, Kim H, Koh J (2010) Metallothionein-3 regulates lysosomal function in cultured astrocytes under both normal and oxidative conditions. Glia 58:1186-1196
    • (2010) Glia , vol.58 , pp. 1186-1196
    • Lee, S.1    Park, M.2    Kim, H.3    Koh, J.4
  • 18
    • 77958147359 scopus 로고    scopus 로고
    • Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes
    • Lee S, Koh J (2010) Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes. Mol Brain 3:30
    • (2010) Mol Brain , vol.3 , pp. 30
    • Lee, S.1    Koh, J.2
  • 19
    • 0037728629 scopus 로고    scopus 로고
    • Differential regulation of metallothionein-I, II, and III mRNA expression in the rat brain following kainic acid treatment
    • DOI 10.1097/00001756-200304150-00004
    • Kim D, Kim EH, Kim C, Sun W, Kim HJ, Uhm CS, Park SH, Kim H (2003) Differential regulation of metallothionein-I, II, and III mRNA expression in the rat brain following kainic acid treatment. Neuroreport 14:679-682 (Pubitemid 36570921)
    • (2003) NeuroReport , vol.14 , Issue.5 , pp. 679-682
    • Kim, D.1    Kim, E.H.2    Kim, C.3    Sun, W.4    Kim, H.J.5    Uhm, C.-S.6    Park, S.-H.7    Kim, H.8
  • 20
    • 0026265241 scopus 로고
    • Glial immunoreactivity for metallothionein in the rat brain
    • Young JK, Garvey JS, Huang PC (1991) Glial immunoreactivity for metallothionein in the rat brain. Glia 4:602-610
    • (1991) Glia , vol.4 , pp. 602-610
    • Young, J.K.1    Garvey, J.S.2    Huang, P.C.3
  • 21
    • 0346457011 scopus 로고    scopus 로고
    • Neuron-glia communication: Metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury
    • Chung RS, Adlard PA, Dittmann J, Vickers JC, Chuah MI, West AK (2004) Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury. J Neurochem 88:454-461 (Pubitemid 38084561)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.2 , pp. 454-461
    • Chung, R.S.1    Adlard, P.A.2    Dittmann, J.3    Vickers, J.C.4    Chuah, M.I.5    West, A.K.6
  • 22
    • 34547683905 scopus 로고    scopus 로고
    • Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia
    • DOI 10.1016/j.neuroscience.2007.04.063, PII S0306452207005453
    • Wakida SM, Hozumi I, Satoh NH, Inuzuka T, Hara H (2007) Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia. Neuroscience 148:105-114 (Pubitemid 47211609)
    • (2007) Neuroscience , vol.148 , Issue.1 , pp. 105-114
    • Wakida, K.1    Shimazawa, M.2    Hozumi, I.3    Satoh, M.4    Nagase, H.5    Inuzuka, T.6    Hara, H.7
  • 23
    • 3042713310 scopus 로고    scopus 로고
    • Zn and Cu alteration in connection with astrocyte metallothionein I/II overexpression in the mouse brain upon physical stress
    • DOI 10.1002/glia.20020
    • Beltramini M, Di Pisa C, Zambenedetti P, Wittkowski W, Mocchegiani E, Musicco M, Zatta P (2004) Zn and Cu alteration in connection with astrocyte metallothionein I/II overexpression in the mouse brain upon physical stress. Glia 47:30-34 (Pubitemid 38879703)
    • (2004) GLIA , vol.47 , Issue.1 , pp. 30-34
    • Beltramini, M.1    Di, P.C.2    Zambenedetti, P.3    Wittkowski, W.4    Mocchegianni, E.5    Musicco, M.6    Zatta, P.7
  • 24
    • 0032127594 scopus 로고    scopus 로고
    • Metallothioneins are highly expressed in astrocytes and microcapillaries in Alzheimer's disease
    • DOI 10.1016/S0891-0618(98)00024-6, PII S0891061898000246
    • Zambenedetti P, Giordano R, Zatta P (1998) Metallothioneins are highly expressed in astrocytes and microcapillaries in Alzheimer's disease. J Chem Neuroanat 15:21-26 (Pubitemid 28377051)
    • (1998) Journal of Chemical Neuroanatomy , vol.15 , Issue.1 , pp. 21-26
    • Zambenedetti, P.1    Giordano, R.2    Zatta, P.3
  • 25
    • 0036667520 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein-positive cells of the kidney are capable of raising a protective biochemical barrier similar to astrocytes: Expression of metallothionein in podocytes
    • DOI 10.1002/ar.10115
    • Buniatian GH, Hartmann HJ, Traub P, Wiesinger H, Albinus M, Nagel W, Shoeman R, Mecke D, Weser U (2002) Glial fibrillary acidic protein-positive cells of the kidney are capable of raising a protective biochemical barrier similar to astrocytes: expression of metallothionein in podocytes. Anat Rec 267:296-306 (Pubitemid 34827617)
    • (2002) Anatomical Record , vol.267 , Issue.4 , pp. 296-306
    • Buniatian, G.H.1    Hartmann, H.-J.2    Traub, P.3    Wiesinger, H.4    Albinus, M.5    Nagel, W.6    Shoeman, R.7    Mecke, D.8    Weser, U.9
  • 26
    • 33745714070 scopus 로고    scopus 로고
    • Region-dependent differences and alterations of protective thiol compound levels in cultured astrocytes and brain tissues
    • Adachi T, Satoh M, Pramanik R, Kuroda S, Ishido M, Kunimoto M (2006) Region-dependent differences and alterations of protective thiol compound levels in cultured astrocytes and brain tissues. Biol Pharm Bull 29:1466-1469
    • (2006) Biol Pharm Bull , vol.29 , pp. 1466-1469
    • Adachi, T.1    Satoh, M.2    Pramanik, R.3    Kuroda, S.4    Ishido, M.5    Kunimoto, M.6
  • 27
    • 33751546646 scopus 로고    scopus 로고
    • Metallothionein-I and -III expression in animal models of Alzheimer disease
    • DOI 10.1016/j.neuroscience.2006.08.054, PII S0306452206011195
    • Carrasco J, Adlard P, Cotman C, Quintana A, Penkowa M, Xu F, Van Nostrand W, Hidalgo J (2006) Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience 143:911-922 (Pubitemid 44834444)
    • (2006) Neuroscience , vol.143 , Issue.4 , pp. 911-922
    • Carrasco, J.1    Adlard, P.2    Cotman, C.3    Quintana, A.4    Penkowa, M.5    Xu, F.6    Van Nostrand, W.E.7    Hidalgo, J.8
  • 29
    • 33749573914 scopus 로고    scopus 로고
    • Quantitative immunogold study of increased expression of metallothionein-I/II in the brain perivascular areas of diabetic scrapie-infected mice
    • DOI 10.1007/s10735-006-9053-6
    • Vorbrodt AW, Dobrogowska DH, Meeker HC, Carp RI (2006) Quantitative immunogold study of increased expression of metallothionein-I/II in the brain perivascular areas of diabetic scrapie-infected mice. J Mol Histol 37:143-151 (Pubitemid 44532064)
    • (2006) Journal of Molecular Histology , vol.37 , Issue.3-4 , pp. 143-151
    • Vorbrodt, A.W.1    Dobrogowska, D.H.2    Meeker, H.C.3    Carp, R.I.4
  • 31
    • 31344462067 scopus 로고    scopus 로고
    • Metallothionein-I-II and GFAP positivity in the brains from frontotemporal dementia patients
    • Zatta P, Zambenedetti P, Musicco M, Adorni F (2005) Metallothionein-I-II and GFAP positivity in the brains from frontotemporal dementia patients. J Alzheimers Dis 8:109-115
    • (2005) J Alzheimers Dis , vol.8 , pp. 109-115
    • Zatta, P.1    Zambenedetti, P.2    Musicco, M.3    Adorni, F.4
  • 32
    • 0036966986 scopus 로고    scopus 로고
    • Metallothionein I-II immunocytochemical reactivity in Binswanger's encephalopathy
    • Zambenedetti P, Schmitt HP, Zatta P (2002) Metallothionein I-II immunocytochemical reactivity in Binswanger's encephalopathy. J Alzheimers Dis 4:459-466 (Pubitemid 36142835)
    • (2002) Journal of Alzheimer's Disease , vol.4 , Issue.6 , pp. 459-466
    • Zambenedetti, P.1    Schmitt, H.P.2    Zatta, P.3
  • 33
    • 33644658492 scopus 로고    scopus 로고
    • Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease
    • DOI 10.1007/s10048-005-0020-2
    • Moran LB, Duke DC, Deprez M, Dexter DT, Pearce RK, Graeber MB (2006) Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease. Neurogenetics 7:1-11 (Pubitemid 43327678)
    • (2006) Neurogenetics , vol.7 , Issue.1 , pp. 1-11
    • Moran, L.B.1    Duke, D.C.2    Deprez, M.3    Dexter, D.T.4    Pearce, R.K.B.5    Graeber, M.B.6
  • 34
    • 23044502947 scopus 로고    scopus 로고
    • Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms
    • DOI 10.1002/ajmg.b.30195
    • Zhang Y, James M, Middleton FA, Davis RL (2005) Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Am J Med Genet B Neuropsychiatr Genet 137:5-16 (Pubitemid 41076605)
    • (2005) American Journal of Medical Genetics - Neuropsychiatric Genetics , vol.137 B , Issue.1 , pp. 5-16
    • Zhang, Y.1    James, M.2    Middleton, F.A.3    Davis, R.L.4
  • 35
    • 38649121744 scopus 로고    scopus 로고
    • Towards a pathway definition of Parkinson's disease: A complex disorder with links to cancer, diabetes and inflammation
    • Moran LB, Graeber MB (2008) Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation. Neurogenetics 9:1-13
    • (2008) Neurogenetics , vol.9 , pp. 1-13
    • Moran, L.B.1    Graeber, M.B.2
  • 37
    • 0242317675 scopus 로고    scopus 로고
    • Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis
    • Peirson SN, Butler JN, Foster RG (2003) Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31:e73
    • (2003) Nucleic Acids Res , vol.31
    • Peirson, S.N.1    Butler, J.N.2    Foster, R.G.3
  • 38
    • 0030781471 scopus 로고    scopus 로고
    • Astrocyte metallothioneins (MTs) and their neuroprotective role
    • Aschner M (1997) Astrocyte metallothioneins (MTs) and their neuroprotective role. Ann N Y Acad Sci 825:334-347
    • (1997) Ann N Y Acad Sci , vol.825 , pp. 334-347
    • Aschner, M.1
  • 43
    • 0038066517 scopus 로고    scopus 로고
    • Expression of metallothionein-III induced by hypoxia attenuates hypoxia-induced cell death in vitro
    • DOI 10.1016/S0006-8993(03)02633-7
    • Tanji K, Irie Y, Uchida Y, Mori F, Satoh K, Mizushima Y, Wakabayashi K (2003) Expression of metallothionein-III induced by hypoxia attenuates hypoxia-induced cell death in vitro. Brain Res 976:125-129 (Pubitemid 36588544)
    • (2003) Brain Research , vol.976 , Issue.1 , pp. 125-129
    • Tanji, K.1    Irie, Y.2    Uchida, Y.3    Mori, F.4    Satoh, K.5    Mizushima, Y.6    Wakabayashi, K.7
  • 45
    • 0035075017 scopus 로고    scopus 로고
    • Astrocyte-targeted expression of interleukin-3 and interferon-alpha causes region-specific changes in metallothionein expression in the brain
    • DOI 10.1006/exnr.2000.7601
    • Giralt M, Carrasco J, Penkowa M, Morcillo MA, Santamaria J, Campbell IL, Hidalgo J (2001) Astrocyte-targeted expression ofinterleukin-3 and interferon-alpha causes region-specific changes in metallothionein expression in the brain. Exp Neurol 168:334-346 (Pubitemid 32289769)
    • (2001) Experimental Neurology , vol.168 , Issue.2 , pp. 334-346
    • Giralt, M.1    Carrasco, J.2    Penkowa, M.3    Angel, M.M.4    Santamaria, J.5    Campbell, I.L.6    Hidalgo, J.7
  • 47
    • 0038407699 scopus 로고    scopus 로고
    • Metallothionein-I overexpression alters brain inflammation and stimulates brain repair in transgenic mice with astrocyte - Targeted interleukin-6 expression
    • DOI 10.1002/glia.10208
    • Penkowa M, Camats J, Giralt M, Molinero A, Hernández J, Carrasco J, Campbell IL, Hidalgo J (2003) Metallothionein-I overexpression alters brain inflammation and stimulates brain repair in transgenic mice with astrocyte-targeted interleukin-6 expression. Glia 42:287-306 (Pubitemid 36538341)
    • (2003) GLIA , vol.42 , Issue.3 , pp. 287-306
    • Penkowa, M.1    Camats, J.2    Giralt, M.3    Molinero, A.4    Hernandez, J.5    Carrasco, J.6    Campbell, I.L.7    Hidalgo, J.8
  • 48
    • 0036402907 scopus 로고    scopus 로고
    • M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6-aminonicotinamide treatment
    • DOI 10.1006/exnr.2002.7968
    • Penkowa M, Poulsen C, Carrasco J, Hidalgo J (2002) M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6- aminonicotinamide treatment. Exp Neurol 176:308-321 (Pubitemid 35193347)
    • (2002) Experimental Neurology , vol.176 , Issue.2 , pp. 308-321
    • Penkowa, M.1    Poulsen, C.B.2    Carrasco, J.3    Hidalgo, J.4
  • 49
    • 33746263669 scopus 로고    scopus 로고
    • Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice
    • DOI 10.1016/j.expneurol.2006.02.011, PII S0014488606000665
    • Wiese L, Kurtzhals JA, Penkowa M (2006) Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice. Exp Neurol 200:216-226 (Pubitemid 44097022)
    • (2006) Experimental Neurology , vol.200 , Issue.1 , pp. 216-226
    • Wiese, L.1    Kurtzhals, J.A.L.2    Penkowa, M.3
  • 50
    • 0346363802 scopus 로고    scopus 로고
    • Zinc- or cadmium-pre-induced metallothionein protects human central nervous system cells and astrocytes from radiation-induced apoptosis
    • DOI 10.1016/j.toxlet.2003.09.013
    • Cai L, Iskander S, Cherian MG, Hammond RR (2004) Zinc- or cadmium-pre-induced metallothionein protects human central nervous system cells and astrocytes from radiation-induced apoptosis. Toxicol Lett 146:217-226 (Pubitemid 37542397)
    • (2004) Toxicology Letters , vol.146 , Issue.3 , pp. 217-226
    • Cai, L.1    Iskander, S.2    Cherian, M.G.3    Hammond, R.R.4
  • 51
    • 0036148593 scopus 로고    scopus 로고
    • Metallothionein-1+2 protect the CNS after a focal brain injury
    • DOI 10.1006/exnr.2001.7772
    • Giralt M, Penkowa M, Lago N, Molinero A, Hidalgo J (2002) Metallothionein-1+2 protect the CNS after a focal brain injury. Exp Neurol 173:114-128 (Pubitemid 34081731)
    • (2002) Experimental Neurology , vol.173 , Issue.1 , pp. 114-128
    • Giralt, M.1    Penkowa, M.2    Lago, N.3    Molinero, A.4    Hidalgo, J.5
  • 52
    • 14144255777 scopus 로고    scopus 로고
    • Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures
    • DOI 10.1002/jnr.20387
    • Penkowa M, Florit S, Giralt M, Quintana A, Molinero A, Carrasco J, Hidalgo J (2005) Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures. J Neurosci Res 79:522-534 (Pubitemid 40283352)
    • (2005) Journal of Neuroscience Research , vol.79 , Issue.4 , pp. 522-534
    • Penkowa, M.1    Florit, S.2    Giralt, M.3    Quintana, A.4    Molinero, A.5    Carrasco, J.6    Hidalgo, J.7
  • 53
    • 15744391811 scopus 로고    scopus 로고
    • Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins
    • Ebadi M, Sharma SK, Ghafourifar P, Brown-Borg H, El Refaey H (2005) Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins. Meth Enzymol 396:276-298
    • (2005) Meth Enzymol , vol.396 , pp. 276-298
    • Ebadi, M.1    Sharma, S.K.2    Ghafourifar, P.3    Brown-Borg, H.4    El Refaey, H.5
  • 54
    • 33749610125 scopus 로고    scopus 로고
    • Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease
    • Ebadi M, Sharma S (2006) Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease. Exp Biol Med (Maywood, NJ) 231:1576-1583 (Pubitemid 44547853)
    • (2006) Experimental Biology and Medicine , vol.231 , Issue.9 , pp. 1576-1583
    • Ebadi, M.1    Sharma, S.2
  • 55
    • 12544253496 scopus 로고    scopus 로고
    • Astroglial nitration after postnatal excitotoxic damage: Correlation with nitric oxide sources, cytoskeletal, apoptotic and antioxidant proteins
    • Acarin L, Peluffo H, Barbeito L, Castellano B, González B (2005) Astroglial nitration after postnatal excitotoxic damage: correlation with nitric oxide sources, cytoskeletal, apoptotic and antioxidant proteins. J Neurotrauma 22:189-200
    • (2005) J Neurotrauma , vol.22 , pp. 189-200
    • Acarin, L.1    Peluffo, H.2    Barbeito, L.3    Castellano, B.4    González, B.5
  • 56
    • 33646878524 scopus 로고    scopus 로고
    • Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons
    • Kooncumchoo P, Sharma S, Porter J, Govitrapong P, Ebadi M (2006) Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons. J Mol Neurosci 28:125-141
    • (2006) J Mol Neurosci , vol.28 , pp. 125-141
    • Kooncumchoo, P.1    Sharma, S.2    Porter, J.3    Govitrapong, P.4    Ebadi, M.5
  • 57
    • 33646864094 scopus 로고    scopus 로고
    • Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10
    • Sharma SK, El Refaey H, Ebadi M (2006) Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10. Brain Res Bull 70:22-32
    • (2006) Brain Res Bull , vol.70 , pp. 22-32
    • Sharma, S.K.1    El Refaey, H.2    Ebadi, M.3
  • 58
    • 0023147742 scopus 로고
    • +
    • DOI 10.1016/0304-3940(87)90543-X
    • Ransom BR, Kunis DM, Irwin I, Langston JW (1987) Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+. Neurosci Lett 75:323-328 (Pubitemid 17042867)
    • (1987) Neuroscience Letters , vol.75 , Issue.3 , pp. 323-328
    • Ransom, B.R.1    Kunis, D.M.2    Irwin, I.3    Langston, J.W.4
  • 59
    • 33644898880 scopus 로고    scopus 로고
    • Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: Astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase
    • Ishida Y, Nagai A, Kobayashi S, Kim SU (2006) Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase. J Neuropathol Exp Neurol 65:66-77
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 66-77
    • Ishida, Y.1    Nagai, A.2    Kobayashi, S.3    Kim, S.U.4
  • 61
    • 34547727312 scopus 로고    scopus 로고
    • Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease
    • DOI 10.1007/s00401-007-0244-3
    • Braak H, Sastre M, Del Tredici K (2007) Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease. Acta Neuropathol 114:231-241 (Pubitemid 47226149)
    • (2007) Acta Neuropathologica , vol.114 , Issue.3 , pp. 231-241
    • Braak, H.1    Sastre, M.2    Del, T.K.3
  • 62
    • 47349104402 scopus 로고    scopus 로고
    • Glial reactions in Parkinson's disease
    • McGeer PL, McGeer EG (2008) Glial reactions in Parkinson's disease. Mov Disord 23:474-483
    • (2008) Mov Disord , vol.23 , pp. 474-483
    • McGeer, P.L.1    McGeer, E.G.2
  • 63
    • 33746104816 scopus 로고    scopus 로고
    • Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease
    • DOI 10.1007/s10048-006-0033-5
    • Duke DC, Moran LB, Kalaitzakis ME, Deprez M, Dexter DT, Pearce RK, Graeber MB (2006) Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease. Neurogenetics 7:139-148 (Pubitemid 44078291)
    • (2006) Neurogenetics , vol.7 , Issue.3 , pp. 139-148
    • Duke, D.C.1    Moran, L.B.2    Kalaitzakis, M.E.3    Deprez, M.4    Dexter, D.T.5    Pearce, R.K.B.6    Graeber, M.B.7
  • 65
    • 33846787163 scopus 로고    scopus 로고
    • Metallothionein I and II attenuate the thalamic microglial response following traumatic axotomy in the immature brain
    • DOI 10.1089/neu.2006.0056.R1
    • Potter E, Cheng Y, Knight J, Gordish-Dressman H, Natale J (2007) Metallothionein I and II attenuate the thalamic microglial response following traumatic axotomy in the immature brain. J Neurotrauma 24:28-42 (Pubitemid 46214410)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.1 , pp. 28-42
    • Potter, E.G.1    Cheng, Y.2    Knight, J.B.3    Gordish-Dressman, H.4    Natale, J.E.5
  • 66
    • 33847209892 scopus 로고    scopus 로고
    • Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
    • Lederer CW, Torrisi A, Pantelidou M, Santama N, Cavallaro S (2007) Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. BMC Genomics 8:26
    • (2007) BMC Genomics , vol.8 , pp. 26
    • Lederer, C.W.1    Torrisi, A.2    Pantelidou, M.3    Santama, N.4    Cavallaro, S.5
  • 68
    • 33644505507 scopus 로고    scopus 로고
    • Human-specific nonsensemutations identified by genome sequence comparisons
    • Hahn Y, Lee B (2006) Human-specific nonsensemutations identified by genome sequence comparisons. Hum Genet 119(1-2):169-178
    • (2006) Hum Genet , vol.119 , Issue.1-2 , pp. 169-178
    • Hahn, Y.1    Lee, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.