An osteoconductive, osteoinductive, and osteogenic tissue-engineered product for trauma and orthopaedic surgery: How far are we?

Stem Cells International

Volumn , Issue , 2012, Pages

  Khan, Wasim S ^a   Rayan, Faizal ^a   Dhinsa, Baljinder S ^a   Marsh, David ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; CALCIUM PHOSPHATE; CALCIUM SULFATE; GLASS; HYALURONIC ACID; HYDROXYAPATITE; MACROGOL; OSTEOGENIC PROTEIN 1; POLYANHYDRIDE; POLYDIOXANONE; POLYGLACTIN; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYURETHAN; TISSUE SCAFFOLD;

ADIPOSE DERIVED STEM CELL; BIOCOMPATIBILITY; BIODEGRADABILITY; BONE DEFECT; BONE GRAFT; BONE PROSTHESIS; BONE REGENERATION; BONE REMODELING; CELL DIFFERENTIATION; CERAMIC PROSTHESIS; EMBRYONIC STEM CELL; HEMATOPOIETIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; ORTHOPEDIC SURGERY; OSSIFICATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; STEM CELL EXPANSION; TISSUE ENGINEERING; TRAUMATOLOGY;

EID: 84855275502     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2012/236231     Document Type: Review

References (86)

1. Tang Y., Wu X., Lei W., Pang L., Wan C., Shi Z., Zhao L., Nagy T. R., Peng X., Hu J., Feng X., Van Hul W., Wan M., Cao X., TGF-beta 1-induced migration of bone mesenchymal stem cells couples bone resorption with formation Nature Medicine 2009 15 7 757 765
2. Kruyt M. C., van Gaalen S. M., Oner F. C., Verbout A. J., De Bruijn J. D., Dhert W. J. A., Bone tissue engineering and spinal fusion: the potential of hybrid constructs by combining osteoprogenitor cells and scaffolds Biomaterials 2004 25 9 1463 1473 (Pubitemid 38094311)
3. Artico M., Ferrante L., Pastore F. S., Ramundo E. O., Cantarelli D., Scopelliti D., Iannetti G., Bone autografting of the calvaria and craniofacial skeleton: historical background, surgical results in a series of 15 patients, and review of the literature Surgical Neurology 2003 60 1 71 79 (Pubitemid 36818962)
4. Konttinen Y. T., Zhao D., Beklen A., Ma G., Takagi M., Kivela-Rajamaki M., Ashammakhi N., Santavirta S., The microenvironment around total hip replacement prostheses Clinical Orthopaedics and Related Research 2005 430 28 38 (Pubitemid 40096129)
5. Mercuri L. G., Giobbie-Hurder A., Long-term outcomes after total alloplastic temporomandibular joint reconstruction following exposure to failed materials Journal of Oral and Maxillofacial Surgery 2004 62 9 1088 1096 (Pubitemid 39165360)
6. Pou A. M., Update on new biomaterials and their use in reconstructive surgery Current Opinion in Otolaryngology and Head and Neck Surgery 2003 11 4 240 244 (Pubitemid 36859675)
7. Langer R., Vacanti J. P., Tissue engineering Science 1993 260 5110 920 926 (Pubitemid 23209960)
8. Govender S., Csimma C., Genant H. K., Valentin-Opran A., Amit Y., Arbel R., Aro H., Atar D., Bishay M., Brner M. G., Chiron P., Choong P., Cinats J., Courtenay B., Feibel R., Geulette B., Govender S., Gravel C., Haas N., Raschke M., Hammacher E., Van der Velde D., Hardy P., Holt M., Josten C., Ketterl R. L., Lindeque B., Lob G., Mathevon H., McCoy G., Marsh D., Miller R., Munting E., Oevre S., Nordsletten L., Patel A., Pohl A., Rennie W., Reynders P., Rommens P. M., Rondia J., Rossouw W. C., Daneel P. J., Ruff S., Rter A., Santavirtal S., Schidhauer T. A., Gekle C., Schnettler R., Segal D., Seiler H., Snowdowne R. B., Stapert J., Taglang G., Verdonik R., Vogels L., Weckbach A., Wentzensen A., Wisriewsk T., Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients Journal of Bone and Joint Surgery: Series A 2002 84 12 2123 2134 (Pubitemid 35417689)
9. Mailhot J. M., Borke J. L., An isolation and in vitro culturing method for human intraoral bone cells derived from dental implant preparation sites Clinical Oral Implants Research 1998 9 1 43 50
10. Hutmacher D. W., Sittinger M., Periosteal cells in bone tissue engineering Tissue Engineering 2003 9 1 S45 S64 (Pubitemid 37046606)
11. Kimelman N., Pelled G., Helm G. A., Huard J., Schwarz E. M., Gazit D., Review: gene- and stem cell-based therapeutics for bone regeneration and repair Tissue Engineering 2007 13 6 1135 1150 (Pubitemid 46986715)
12. Stewart D. A., Guo D., Luider J., Auer I., Klassen J., Ching E., Morris D., Chaudhry A., Brown C., Russell J. A., Factors predicting engraftment of autologous blood stem cells: CD34+ subsets inferior to the total CD34+ cell dose Bone Marrow Transplantation 1999 23 12 1237 1243 (Pubitemid 29312929)
13. Partridge K. A., Oreffo R. O. C., Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies Tissue Engineering 2004 10 1-2 295 307 (Pubitemid 38199384)
14. Cancedda R., Bianchi G., Derubeis A., Quarto R., Cell therapy for bone disease: a review of current status Stem Cells 2003 21 5 610 619 (Pubitemid 37444117)
15. Porter B. D., Oldham J. B., He S. L., Zobitz M. E., Payne R. G., An K. N., Currier B. L., Mikos A. G., Yaszemski M. J., Mechanical properties of a biodegradable bone regeneration scaffold Journal of Biomechanical Engineering 2000 122 3 286 288 (Pubitemid 30483246)
16. Wang J., Qu L., Meng X., Gao J., Li H., Wen G., Preparation and biological properties of PLLA/ -TCP composites reinforced by chitosan fibers Biomedical Materials 2008 3 2
17. Yu H., Matthew H. W., Wooley P. H., Yang S. Y., Effect of porosity and pore size on microstructures and mechanical properties of poly-epsilon- caprolactone- hydroxyapatite composites Journal of Biomedical Materials Research: Part B 2008 86 2 541 547
18. Giannoudis P. V., Dinopoulos H., Tsiridis E., Bone substitutes: an update Injury 2005 36 S20 S27
19. Ahlmann E., Patzakis M., Roidis N., Shepherd L., Holtom P., Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes Journal of Bone and Joint Surgery 2002 84 5 716 720
20. Li J., Wang H. L., Common implant-related advanced bone grafting complications: classification, etiology, and management Implant Dentistry 2008 17 4 389 401
21. Bianco P., Riminucci M., Gronthos S., Robey P. G., Bone marrow stromal stem cells: nature, biology, and potential applications Stem Cells 2001 19 3 180 192 (Pubitemid 32524539)
22. Yang S., Leong K. F., Du Z., Chua C. K., The design of scaffolds for use in tissue engineering. Part I. Traditional factors Tissue Engineering 2001 7 6 679 689 (Pubitemid 34042301)
23. Itoh K., Udagawa N., Katagiri T., Iemura S., Ueno N., Yasuda H., Higashio K., Quinn J. M. W., Gillespie M. T., Martin T. J., Suda T., Takahashi N., Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor- B ligand Endocrinology 2001 142 8 3656 3662 (Pubitemid 32681777)
24. Kaneko H., Arakawa T., Mano H., Kaneda T., Ogasawara A., Nakagawa M., Toyama Y., Yabe Y., Kumegawa M., Hakeda Y., Direct stimulation of osteoclastic bone resorption by bone morphogenetic protein (BMP)-2 and expression of BMP receptors in mature osteoclasts Bone 2000 27 4 479 486
25. Caplan A. I., Adult mesenchymal stem cells for tissue engineering versus regenerative medicine Journal of Cellular Physiology 2007 213 2 341 347 (Pubitemid 47509711)
26. Mauney J. R., Kaplan D. L., Volloch V., Matrix-mediated retention of osteogenic differentiation potential by human adult bone marrow stromal cells during ex vivo expansion Biomaterials 2004 25 16 3233 3243 (Pubitemid 38234784)
27. Gimble J. M., Katz A. J., Bunnell B. A., Adipose-derived stem cells for regenerative medicine Circulation Research 2007 100 9 1249 1260 (Pubitemid 46742916)
28. Zuk P. A., Zhu M., Mizuno H., Huang J., Futrell J. W., Katz A. J., Benhaim P., Lorenz H. P., Hedrick M. H., Multilineage cells from human adipose tissue: implications for cell-based therapies Tissue Engineering 2001 7 2 211 228 (Pubitemid 32295155)
29. Cowan C. M., Shi Y. Y., Aalami O. O., Chou Y. F., Mari C., Thomas R., Quarto N., Contag C. H., Wu B., Longaker M. T., Adipose-derived adult stromal cells heal critical-size mouse calvarial defects Nature Biotechnology 2004 22 5 560 567 (Pubitemid 38585908)
30. Yoon E., Dhar S., Chun D. E., Gharibjanian N. A., Evans G. R. D., In vivo osteogenic potential of human adipose-derived stem cells/poly lactide-co-glycolic acid constructs for bone regeneration in a rat critical-sized calvarial defect model Tissue Engineering 2007 13 3 619 627 (Pubitemid 46579887)
31. Takahashi K., Yamanaka S., Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 2006 126 4 663 676 (Pubitemid 44233629)
32. Okita K., Nakagawa M., Hyenjong H., Ichisaka T., Yamanaka S., Generation of mouse induced pluripotent stem cells without viral vectors Science 2008 322 5903 949 953
33. Thomson J. A., Itskovitz-Eldor J., Shapiro S. S., Embryonic stem cell lines derived from human blastocysts Science 1998 282 5391 1145 1147 (Pubitemid 28516247)
34. Hoffman L. M., Carpenter M. K., Characterization and culture of human embryonic stem cells Nature Biotechnology 2005 23 6 699 708 (Pubitemid 41716360)
35. Fleming J. E. Jr., Cornell C. N., Muschler G. F., Bone cells and matrices in orthopedic tissue engineering Orthopedic Clinics of North America 2000 31 3 357 374 (Pubitemid 30624511)
36. Jupiter J. B., Winters S., Sigman S., Lowe C., Pappas C., Ladd A. L., Van Wagoner M., Smith S. T., Repair of five distal radius fractures with an investigational cancellous bone cement: a preliminary report Journal of Orthopaedic Trauma 1997 11 2 110 116 (Pubitemid 127452352)
37. Kopylov P., Jonsson K., Thorngren K. G., Aspenberg P., Injectable calcium phosphate in the treatment of distal radial fractures Journal of Hand Surgery 1996 21 6 768 771 (Pubitemid 26421312)
38. Rezwan K., Chen Q. Z., Blaker J. J., Boccaccini A. R., Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering Biomaterials 2006 27 18 3413 3431
39. Mikos A. G., Bao Y., Cima L. G., Ingber D. E., Vacanti J. P., Langer R., Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation Journal of Biomedical Materials Research 1993 27 2 183 189 (Pubitemid 23027517)
40. Mikos A. G., Sarakinos G., Leite S. M., Vacanti J. P., Langer R., Laminated three-dimensional biodegradable foams for use in tissue engineering Biomaterials 1993 14 5 323 330 (Pubitemid 23132989)
41. Mooney D. J., Baldwin D. F., Suh N. P., Vacanti J. P., Langer R., Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents Biomaterials 1996 17 14 1417 1422 (Pubitemid 26237549)
42. Kothapalli C. R., Shaw M. T., Wei M., Biodegradable HA-PLA 3-D porous scaffolds: effect of nano-sized filler content on scaffold properties Acta Biomaterialia 2005 1 6 653 662 (Pubitemid 43348758)
43. Porter J. R., Ruckh T. T., Popat K. C., Bone tissue engineering: a review in bone biomimetics and drug delivery strategies Biotechnology Progress 2009 25 6 1539 1560
44. Christenson E. M., Anseth K. S., Van den Beucken J. J. J. P., Chan C. K., Ercan B., Jansen J. A., Laurencin C. T., Li W. J., Murugan R., Nair L. S., Ramakrishna S., Tuan R. S., Webster T. J., Mikos A. G., Nanobiomaterial applications in orthopedics Journal of Orthopaedic Research 2007 25 1 11 22 (Pubitemid 46070727)
45. Chlopek J., Morawska-Chochol A., Bajor G., The influence of carbon fibres on the resorption time and mechanical properties of the lactide-glycolide co-polymer Journal of Biomaterials Science 2007 18 11 1355 1368 (Pubitemid 47622369)
46. Kaufman J. D., Song J., Klapperich C. M., Nanomechanical analysis of bone tissue engineering scaffolds Journal of Biomedical Materials Research: Part A 2007 81 3 611 623 (Pubitemid 46786892)
47. Kneser U., Schaefer D. J., Polykandriotis E., Horch R. E., Tissue engineering of bone: the reconstructive surgeon's point of view Journal of Cellular and Molecular Medicine 2006 10 1 7 19 (Pubitemid 44882940)
48. Schantz J. T., Hutmacher D. W., Lam C. X. F., Brinkmann M., Wong K. M., Lim T. C., Chou N., Guldberg R. E., Teoh S. H., Repair of calvarial defects with customised tissue-engineered bone grafts II. Evaluation of cellular efficiency and efficacy in vivo Tissue Engineering 2003 9 1 S127 S139 (Pubitemid 37046612)
49. Reddi A. H., Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials Tissue Engineering 2000 6 4 351 359 (Pubitemid 30655945)
50. Dimitriou R., Dahabreh Z., Katsoulis E., Matthews S. J., Branfoot T., Giannoudis P. V., Application of recombinant BMP-7 on persistent upper and lower limb non-unions Injury 2005 36 4 S51 S59 (Pubitemid 41608591)
51. Yu N. Y., Schindeler A., Little D. G., Ruys A. J., Biodegradable poly(alpha-hydroxy acid) polymer scaffolds for bone tissue engineering Journal of Biomedical Materials Research: Part B 2010 93 1 285 295
52. Gonda K., Nakaoka T., Yoshimura K., Otawara-Hamamoto Y., Harrii K., Heterotopic ossification of degenerating rat skeletal muscle induced by adenovirus-mediated transfer of bone morphogenetic protein-2 gene Journal of Bone and Mineral Research 2000 15 6 1056 1065 (Pubitemid 30350068)
53. Zhang X., Xie C., Lin A. S., Ito H., Awad H., Lieberman J. R., Rubery P. T., Schwarz E. M., O'Keefe R. J., Guldberg R. E., Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering Journal of Bone and Mineral Research 2005 20 12 2124 2137 (Pubitemid 41698776)
54. Olsen D., Yang C., Bodo M., Chang R., Leigh S., Baez J., Carmichael D., Jarvinen M., Polarek J., Recombinant collagen and gelatin for drug delivery Advanced Drug Delivery Reviews 2003 55 12 1547 1567 (Pubitemid 37412593)
55. Matsushita N., Terai H., Okada T., A new bone-inducing biodegradable porous beta-tricalcium phosphate Journal of Biomedical Materials Research 2004 70 3 450 458 (Pubitemid 39145245)
56. Murakami N., Saito N., Horiuchi H., Okada T., Nozaki K., Takaoka K., Repair of segmental defects in rabbit humeri with titanium fiber mesh cylinders containing recombinant human bone morphogenetic protein-2 (rhBMP-2) and a synthetic polymer Journal of Biomedical Materials Research 2002 62 2 169 174 (Pubitemid 34988493)
57. Sikavitsas V. I., Bancroft G. N., Mikos A. G., Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor Journal of Biomedical Materials Research 2002 62 1 136 148 (Pubitemid 34831402)
58. Bancroft G. N., Sikavitsas V. I., Mikos A. G., Design of a flow perfusion bioreactor system for bone tissue-engineering applications Tissue Engineering 2003 9 3 549 554 (Pubitemid 36736136)
59. Sikavitsas V. I., Bancroft G. N., Lemoine J. J., Liebschner M. A. K., Dauner M., Mikos A. G., Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds Annals of Biomedical Engineering 2005 33 1 63 70 (Pubitemid 40496060)
60. Janssen F. W., Oostra J., Van Oorschot A., Van Blitterswijk C. A., A perfusion bioreactor system capable of producing clinically relevant volumes of tissue-engineered bone: in vivo bone formation showing proof of concept Biomaterials 2006 27 3 315 323 (Pubitemid 41457234)
61. Holtorf H. L., Jansen J. A., Mikos A. G., Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor Advances in Experimental Medicine and Biology 2006 585 225 241
62. Petite H., Viateau V., Bensad W., Meunier A., De Pollak C., Bourguignon M., Oudina K., Sedel L., Guillemin G., Tissue-engineered bone regeneration Nature Biotechnology 2000 18 9 959 963 (Pubitemid 32977376)
63. Schimming R., Schmelzeisen R., Tissue-engineered bone for maxillary sinus augmentation Journal of Oral and Maxillofacial Surgery 2004 62 6 724 729 (Pubitemid 38736446)
64. Marcacci M., Kon E., Moukhachev V., Lavroukov A., Kutepov S., Quarto R., Mastrogiacomo M., Cancedda R., Stem cells associated with macroporous bioceramics for long bone repair: 6-to 7-year outcome of a pilot clinical study Tissue Engineering 2007 13 5 947 955 (Pubitemid 46870419)
65. Chimutengwende-Gordon M., Khan W. S., Advances in the use of stem cells and tissue engineering applications in bone repair. Current Stem Cell Research Therapy. In press
66. Gidado S., Khan W. S., Marsh D. R., The effect of changes in oxygen tension during fracture repair on mesenchymal stem cell and bone activities Current Research Journal of Biological Sciences 2009 1 1 7 10
67. Khaled E. G., Saleh M., Hindocha S., Griffin M., Khan W. S., Tissue engineering for bone production- stem cells, gene therapy and scaffolds Open Orthopaedics Journal 2011 5 288 294
68. Khan W. S., Rayanmarakkar F., Marsh D. R., Beckingsworth R. H., Principles of tissue engineering approaches for bone repair in the hand Hand Surgery: Preoperative Expectations, Techniques and Results 2009 New York, NY, USA Nova Science 71 84
69. Khan W. S., Marsh D., Tissue engineering approaches for bone repair: cells, scaffolds, growth factors and gene therapy Stem Cell Research 2010 2 1 21 32
70. Shekkeris A. S., Jaiswal P. K., Khan W. S., Clinical applications of mesenchymal stem cells in the treatment of fracture non-union and bone defects. Current Stem Cell Research Therapy. In press
71. Tucker B. A., Karamsadkar S. S., Khan W. S., Pastides P., The role of bone marrow derived mesenchymal stem cells in sports injuries. Journal of Stem Cells. In press
72. Kanitkar M., Tailor H. D., Khan W. S., The use of growth factors and mesenchymal stem cells in orthopaedics Open Orthopaedics Journal 2011 5 268 274
73. Kennard L., Tailor H. D., Thanabalasundaram G., Khan W. S., Advances and developments in the use of human mesenchymal stem cellsa few considerations Open Orthopaedics Journal 2011 5 245 249
74. Khan W. S., Adesida A. B., Tew S. R., Andrew J. G., Hardingham T. E., The epitope characterisation and the osteogenic differentiation potential of human fat pad-derived stem cells is maintained with ageing in later life Injury 2009 40 2 150 157
75. Khan W. S., Malik A. A., Hardingham T. E., Stem cell applications and tissue engineering approaches in surgical practice Journal of perioperative practice 2009 19 4 130 135
76. Khan W. S., Marsh D. R., A literature review on the effects of ageing on mesenchymal stem cells Current Research Journal of Biological Sciences 2009 1 1 1 6
77. Khan W. S., Foreword: stem cell applications and tissue engineering approaches in sports medicine- from bench to bedside. Journal of Stem Cells. In press
78. Mafi P., Hindocha S., Mafi R., Griffin M., Khan W. S., Sources of adult mesenchymal stem cells applicable for musculoskeletal applications- a systematic review of the literature Open Orthopaedics Journal 2011 5 238 244
79. Mafi P., Hindocha S., Mafi R., Griffin M., Khan W. S., Adult mesenchymal stem cells and cell surface characterization- a systematic review of the literature Open Orthopaedics Journal 2011 5 250 257
80. Mahapatra A., Khan W. S., Editorial: tissue engineering in orthopaedics and musculoskeletal sciences Open Orthopaedics Journal 2011 5 234 237
81. Malik A., Khan W. S., Editorial: stem cell applications and tissue engineering approaches in orthopaedic surgery and musculoskeletal medicine. Current Stem Cell Research Therapy. In press
82. Mohal J. S., Tailor H. D., Khan W. S., Sources of adult mesenchymal stem cells and their applicability for musculoskeletal applications. Current Stem Cell Research Therapy. In press
83. Nannaparaju M., Oragui E., Khan W. S., Xiao Y., The role of stem cells, scaffolds and bioreactors in musculoskeletal tissue engineering Mesenchymal Stem Cells 2011 New York, NY, USA Nova Science
84. Nannaparaju M., Oragui E., Khan W. S., Stem cells, scaffolds and bioreactors in orthopaedic tissue engineering. Stem Cell Research. In press
85. Oragui E., Nannaparaju M., Khan W. S., The role of bioreactors in tissue engineering for musculoskeletal applications Open Orthopaedics Journal 2011 5 264 267
86. Thanabalasundaram G., Arumalla N., Tailor H. D., Khan W. S., Regulation of differentiation of mesenchymal stem cells into musculoskeletal cells. Current Stem Cell Research Therapy. In press