Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor

Advances in Experimental Medicine and Biology

Volumn 585, Issue , 2006, Pages 225-241

  Holtorf, Heidi L ^a   Jansen, John A ^b   Mikos, Antonios G ^a  

^a Rice University   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84934436472     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-34133-0_16     Document Type: Conference Paper

References (54)

1. R. Langer and J. P. Vacanti, Tissue Engineering, Science 260(5110), 920-926 (1993).
2. M. J. Yaszemski, J. B. Oldham, L. Lu and B. L. Currier, Clinical Needs for Bone Tissue-Engineering Technology, in: Bone Engineering, edited by J. E. Davies (em squared incorporated, Toronto, 2000), pp. 541-546.
3. J. A. Buckwalter, M. J. Glimcher, R. R. Cooper and R. Recker, Bone Biology, J. Bone Joint Surg. Am. 77-A(8), 1256-1289 (1995).
4. V. I. Sikavitsas, J. S. Temenoff and A. G. Mikos, Biomaterials and Bone Mechanotransduction, Biomaterials 22(19), 2581-2593 (2001).
5. J. E. Aubin and A. Herbertson, Osteoblast lineage in experimental animals, in: Marrow Stromal Cell Culture, edited by J. N. Beresford and M. Owen (Cambridge University Press, Cambridge, 1998), pp. 88-110.
6. J. E. Aubin, The Osteoblast Lineage, in: Principles of Bone Biology, edited by J. P. Bilezikian, L. G. Raisz and G. A. Rodan (Academic Press, San Diego, 1996), pp. 51-67.
7. J. E. Aubin, Osteogenic Cell Differentiation, in: Bone Engineering, edited by J. E. Davies (em squared incorporated, Toronto, 2000), pp. 19-29.
8. C. Maniatopolous, J. Sodek and A. H. Melcher, Bone formation in in vitro by stromal cells obtained from bone marrow of young adult rats, Cell Tissue Research 254(2), 317-330 (1988).
9. E. Behravesh, K. Zygourakis and A. G. Mikos, Adhesion and migration of marrow-derived osteoblasts on injectable in situ crosslinkable poly(propylene fumarate-co-ethylene glycol)-based hydrogels with a covalently linked RGDS peptide, J. Biomed. Mater. Res. 65A(2), 261-271 (2003).
10. E. Behravesh and A. G. Mikos, Three-dimensional culture of differentiating marrow stromal osteoblasts in biomimetic poly(propylene fumarate-co-ethylene glycol)-based macroporous hydrogels, J. Biomed. Mater. Res. 66A(3), 698-706 (2003).
11. H. Shin, S. Jo and A. G. Mikos, Modulation of marrow stromal osteoblast adhesion on biomimetic oligo[poly(ethylene glycol) fumarate] hydrogels modified with Arg-Gly-Asp peptides and a poly(ethylene glycol) spacer, J. Biomed. Mater. Res. 61A(2), 169-179 (2002).
12. J. S. Temenoff, H. Park, E. Jabbari, D. E. Conway, T. L. Sheffield, C. G. Ambrose and A. G. Mikos, Thermally Cross-Linked Oligo(poly(ethylene glycol) fumarate) Hydrogels Support Osteogenic Differentiation of Encapsulated Marrow Stromal Cells In Vitro, Biomacromolecules 5(1), 5-10 (2004).
13. R. G. Payne, J. S. McGonigle, M. J. Yaszemski, A. W. Yasko and A. G. Mikos, Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 3. Proliferation and differentiation of encapsulated marrow stromal osteoblasts cultured on crosslinking poly(propylene fumarate), Biomaterials 23(22), 4381-4387 (2002).
14. E. Lieb, J. Tessmar, M. Hacker, C. Fischbach, D. Rose, T. Blunk, A. G. Mikos, A. Gopferich and M. B. Schulz, Poly(D,L-lactic acid)-Poly(ethylene glycol)-Monomethyl Ether Diblock Copolymers Control Adhesion and Osteoblastic Differentiation of Marrow Stromal Cells, Tissue Eng. 9(1), 71-84 (2003).
15. M. J. Gilmcher, L. C. Bonar, M. D. Grynpas, W. J. Landis and A. H. Roufosse, Recent studies of bone mineral: Is the amorphous calcium phosphate theory valid?, J. Cryst. Growth 53(1), 100-119 (1981).
16. B. R. Constantz, I. C. Ison, M. T. Fulmer, R. D. Poser, S. T. Smith, M. VanWagoner, J. Ross, S. A. Goldstein, J. B. Jupiter and D. I. Rosenthal, Skeletal Repair by in Situ Formation of the Mineral Phase of Bone, Science 267(5205), 1796-1799 (1995).
17. C. G. Finkemeier, Bone grafting and bone graft substitutes, J. Bone Joint Surg. Am. 84A(3), 454-464 (2002).
18. S. N. Parikh, Bone graft substitutes in modern orthopedics, Orthopedics 25(11), 1301-1309 (2002).
19. J. A. McAuliffe, Bone Graft Substitutes, J. Hand Ther. 16(2), 180-187 (2003).
20. H. Yuan, M. van den Doel, S. Li, C. A. van Blitterswijk, K. de Groot and J. D. de Bruijn, A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats, J. Mater. Sci. Mater. Med. 13(12), 1271-1275 (2002).
21. P. Q. Ruhé, H. C. Kroese-Deutman, J. G. C. Wolke, P. H. M. Spauwen and J. A. Jansen, Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants in cranial defects in rabbits, Biomaterials 25(11), 2123-2132 (2004).
22. E. J. Blom, J. Klein-Nulend, C. P. A. T. Klein, K. Kurashina, M. A. J. van Waas and E. H. Burger, Transforming growth factor-ß1 incorporated during setting in calcium phosphate cement stimulates bone cell differentiation in vitro, J. Biomed. Mater. Res. A 50(1), 67-74 (2000).
23. P. Laffargue, P. Fialdes, P. Frayssinet, M. Rtaimate, H. F. Hildebrand and X. Marchandise, Adsorption and release of insulin-like growth factor-1 on porous tricalcium phosphate implant, J. Biomed. Mater. Res. 49A(3), 415-421 (2000).
24. J. Toquet, R. Rohanizadeh, J. Guicheux, S. Couillaud, N. Passuti, G. Daculsi and D. Heymann, Osteogenic potential in vitro of human bone marrow cells cultured on macroporous biphasic calcium phosphate ceramic, J. Biomed. Mater. Res. 44A(1), 98-108 (1999).
25. T. Kai, G. Shao-qing and D. Geng-ting, In vivo evaluation of bone marrow stromal-derived osteoblastsporous calcium phosphate ceramic composites as bone graft substitute for lumbar intervertebral spine fusion, Spine 28(15), 1653-1658 (2003).
26. J. Goshima, V. M. Goldberg and A. I. Caplan, Osteogenic potential of culture-expanded rat marrow cells as assayed in vivo with porous calcium phosphate ceramic, Biomaterials 12(2), 253-258 (1991).
27. H. Ohgushi, M. Okumura, S. Tamai, E. C. Shors and A. I. Caplan, Marrow cell induced osteogenesis in porous hydroxyapatite and tricalcium phosphate: a comparative histomorphometric study of ectopic bone formation, J. Biomed. Mater. Res. 24A(12), 1563-1570 (1990).
28. J. W. M. Vehof, P. H. M. Spauwen and J. A. Jansen, Bone formation in calcium-phosphate-coated titanium mesh, Biomaterials 21(2003-2009 (2000).
29. J. W. M. Vehof, M. T. Haus, A. E. de Ruijter, P. H. M. Spauwen and J. A. Jansen, Bone formation in transforming growth factor beta-I-loaded titanium fiber mesh implants, Clin. Oral Implants Res. 13(1), 94-102 (2002).
30. J. W. M. Vehof, A. E. de Ruijter, P. H. M. Spauwen and J. A. Jansen, Influence of rhBMP-2 on rat bone marrow stromal cells cultured on titanium fiber mesh, Tissue Eng. 7(4), 373-383 (2001).
31. J. van den Dolder, J. W. M. Vehof, P. H. M. Spauwen and J. A. Jansen, Bone formation by rat bone marrow cells cultured on titanium fiber mesh: effect of in vitro culture time, J. Biomed. Mater. Res. 62A(3), 350-358 (2002).
32. J. W. M. Vehof, J. van den Dolder, J. E. de Ruijter, P. H. M. Spauwen and J. A. Jansen, Bone formation in CaP-coated and noncoated titanium fiber mesh, J. Biomed. Mater. Res. 64A(417-426 (2003).
33. J. W. M. Vehof, J. Mahmood, H. Takita, M. A. van't Hof, Y. Kuboki, P. H. M. Spauwen and J. A. Jansen, Ectopic bone formation in titanium mesh loaded with bone morphogenetic protein and coated with calcium phosphate, Plast. Reconstr. Surg. 108(2), 434-443 (2001).
34. J. van den Dolder, E. Farber, P. H. M. Spauwen and J. A. Jansen, Bone tissue reconstruction using titanium fiber mesh combined with rat bone marrow stromal cells, Biomaterials 24(1745-1750 (2003).
35. J. van den Dolder, P. H. Spauwen and J. A. Jansen, Evaluation of Various Seeding Techniques for Culturing Osteogenic Cells on Titanium Fiber Mesh, Tissue Eng. 9(2), 315-325 (2003).
36. G. Vunjak-Novakovic, B. Obradovic, I. Martin, P. M. Bursac, R. Langer and L. E. Freed, Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering, Biotechnol. Prog. 14(2), 193-202 (1998).
37. B.-S. Kim, A. J. Putnam, T. J. Kulik and D. J. Mooney, Optimizing seeding and culture methods to engineer smooth muscle tissue on biodegradable polymer matrices, Biotechnol. Bioeng. 57(1), 46-54 (1998).
38. J. R. Mauney, J. Blumberg, M. Pirun, V. Volloch, G. Vunjak-Novakovic and D. L. Kaplan, Osteogenic differentiation of human bone marrow stromal cells on partially demineralized bone scaffolds in vitro, Tissue Eng. 10(1-2), 81-92 (2004).
39. R. L. Carrier, M. Papadaki, M. Rupnick, F. J. Schoen, N. Bursac, R. Langer, L. E. Freed and G. Vunjak-Novakovic, Cardiac tissue engineering: cell seeding cultivation parameters, and tissue construct characterization, Biotechnol. Bioeng. 64(5), 580-589 (1999).
40. D. Wendt, A. Marsano, M. Jakob, M. Heberer and I. Martin, Oscillating perfusion of cell suspensions through three-dimensional scaffoldsd enhances cell seeding efficiency and uniformity, Biotechnol. Bioeng. 84(2), 205-214 (2003).
41. W. T. Godbey, B. S. S. Hindy, M. E. Sherman and A. Atala, A novel use of centrifugal force for cell seeding into porous scaffolds, Biomaterials 25(14), 2799-2805 (2004).
42. V. I. Sikavitsas, G. N. Bancroft and A. G. Mikos, Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor, J. Biomed. Mater. Res. 62A(1), 136-148 (2002).
43. A. S. Goldstein, T. M. Juarez, C. D. Helmke, M. C. Gustin and A. G. Mikos, Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds, Biomaterials 22(11), 1279-1288 (2001).
44. L. Meinel, V. Karageorgiou, R. Fajardo, B. Snyder, V. Shinde-Patil, L. Zichner, D. L. Kaplan, R. Langer and G. Vunjak-Novakovic, Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow, Ann. Biomed. Eng. 32(1), 112-122 (2004).
45. G. N. Bancroft, V. I. Sikavitsas and A. G. Mikos, Design of a Flow Perfusion Bioreactor System for Bone Tissue-Engineering Applications, Tissue Eng. 9(3), 549-554 (2003).
46. J. van den Dolder, G. N. Bancroft, V. I. Sikavitsas, P. H. Spauwen, J. A. Jansen and A. G. Mikos, Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh, J. Biomed. Mater. Res. 64A(2), 235-241 (2003).
47. G. N. Bancroft, V. I. Sikavitsas, J. van den Dolder, T. L. Sheffield, C. G. Ambrose, J. A. Jansen and A. G. Mikos, Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner, Proc. Natl. Acad. Sci. U. S. A. 99(20), 12600-12605 (2002).
48. V. I. Sikavitsas, G. N. Bancroft, H. L. Holtorf, J. A. Jansen and A. G. Mikos, Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces, Proc. Natl. Acad. Sci. U. S. A. 100(25), 14683-14688 (2003).
49. M. E. Gomes, V. I. Sikavitsas, E. Behravesh, R. L. Reis and A. G. Mikos, Effect of Flow Perfusion on the Osteogenic Differentiation of Bone Marrow Stromal Cells Cultured on Starch-Based Three-Dimensional Scaffolds, J. Biomed. Mater. Res. 67A(87-95 (2003).
50. V. I. Sikavitsas, G. N. Bancroft, J. J. Lemoine, M. A. K. Liebschner, M. Dauner and A. G. Mikos, Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable non-woven fiber mesh scaffolds, Ann. Biomed. Eng. 33(1), 63-70 (2005).
51. H. L. Holtorf, J. A. Jansen and A. G. Mikos, Ectopic bone formation in rat marrow stromal cell/titanium fiber mesh scaffold constructs: Effect of initial cell phenotype, Biomaterials 26(31), 6208-6216 (2005).
52. N. Datta, H. L. Holtorf, V. I. Sikavitsas, J. A. Jansen and A. G. Mikos, Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells, Biomaterials 26(9), 971-977 (2005).
53. H. L. Holtorf, J. A. Jansen and A. G. Mikos, Flow perfusion culture induces the osteoblastic differentiation of marrow stromal cell-scaffold constructs in the absence of dexamethasone, J. Biomed. Mater. Res. 72A(3), 326-334 (2005).
54. H. L. Holtorf, N. Datta, J. A. Jansen and A. G. Mikos, Scaffold Mesh Size Affects the Osteoblastic Differentiation of Seeded Marrow Stromal Cells Cultured in a Flow Perfusion Bioreactor, J. Biomed. Mater. Res. 74A(2), 171-180 (2005).