메뉴 건너뛰기




Volumn 7, Issue 2, 2012, Pages 95-102

Regulation of differentiation of mesenchymal stem cells into musculoskeletal cells

Author keywords

Adipocytes; Chondrocytes; Differentiation; Mesenchymal stem cells; Myocytes; Osteoblasts; Tenocytes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALKALINE PHOSPHATASE; AXIN2 PROTEIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 12; CALCIUM; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH DIFFERENTIATION FACTOR; ISOBUTYLMETHYLXANTHINE; LEUCINE ZIPPER PROTEIN; LEUKOCYTE ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE; PARATHYROID HORMONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLYCAPROLACTONE; SMAD PROTEIN; SYNAPTOPHYSIN; THIOREDOXIN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 467;

EID: 84857778921     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488812799218974     Document Type: Review
Times cited : (31)

References (69)
  • 1
    • 72849113362 scopus 로고    scopus 로고
    • Characterization of mesenchymal stem cells from rat bone marrow: Ultrastructural properties, differentiation potential and immunophenotypic markers
    • Karaoz E, Aksoy A, Ayhan S, Sariboyaci AE, Kaymaz F, Kasap M. Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers. Histochem Cell Biol 2009; 132(5): 533-46.
    • (2009) Histochem Cell Biol , vol.132 , Issue.5 , pp. 533-546
    • Karaoz, E.1    Aksoy, A.2    Ayhan, S.3    Sariboyaci, A.E.4    Kaymaz, F.5    Kasap, M.6
  • 2
    • 28244440913 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells
    • Kemp KC, Hows J, Donaldson C. Bone marrow-derived mesenchymal stem cells. Leuk Lymphoma 2005; 46(11): 1531-44.
    • (2005) Leuk Lymphoma , vol.46 , Issue.11 , pp. 1531-1544
    • Kemp, K.C.1    Hows, J.2    Donaldson, C.3
  • 3
    • 34250660910 scopus 로고    scopus 로고
    • Stem cells from adipose tissue allow challenging new concepts for regenerative medicine
    • Helder MN, Knippenberg M, Klein-Nulend J, Wuisman PI. Stem cells from adipose tissue allow challenging new concepts for regenerative medicine. Tissue Eng 2007; 13(8): 1799-808.
    • (2007) Tissue Eng , vol.13 , Issue.8 , pp. 1799-17808
    • Helder, M.N.1    Knippenberg, M.2    Klein-Nulend, J.3    Wuisman, P.I.4
  • 4
    • 33846406448 scopus 로고    scopus 로고
    • Stem cells in the umbilical cord
    • Weiss ML, Troyer DL. Stem cells in the umbilical cord. Stem Cell Rev 2006; 2(2): 155-62.
    • (2006) Stem Cell Rev , vol.2 , Issue.2 , pp. 155-162
    • Weiss, M.L.1    Troyer, D.L.2
  • 5
    • 34248355601 scopus 로고    scopus 로고
    • Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells
    • Luu HH, Song WX, Luo X, et al. Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res 2007; 25(5): 665-77.
    • (2007) J Orthop Res , vol.25 , Issue.5 , pp. 665-677
    • Luu, H.H.1    Song, W.X.2    Luo, X.3
  • 6
    • 0141495316 scopus 로고    scopus 로고
    • Existence of reserve quiescent stem cells in adults, from amphibians to humans
    • Young HE. Existence of reserve quiescent stem cells in adults, from amphibians to humans. Curt Top Microbiol immunol 2004; 280: 71-109.
    • (2004) Curt Top Microbiol Immunol , vol.280 , pp. 71-109
    • Young, H.E.1
  • 7
    • 0242495039 scopus 로고    scopus 로고
    • Plasticity of marrow-derived stem cells
    • Herzog EL, Chai L, Krause DS. Plasticity of marrow-derived stem cells. Blood 2003; 102(10): 3483.
    • (2003) Blood , vol.102 , Issue.10 , pp. 3483
    • Herzog, E.L.1    Chai, L.2    Krause, D.S.3
  • 8
    • 77957666829 scopus 로고    scopus 로고
    • Opposite spectrum of activity of canonical Wnt signaling in the osteogenic context of undifferentiated and differentiated mesenchymal cells: Implications for tissue engineering
    • Quarto N, Behr B, Longaker MT. Opposite spectrum of activity of canonical Wnt signaling in the osteogenic context of undifferentiated and differentiated mesenchymal cells: implications for tissue engineering. Tissue Eng Part A 2010; 16(10): 3185-97.
    • (2010) Tissue Eng Part A , vol.16 , Issue.10 , pp. 3185-3197
    • Quarto, N.1    Behr, B.2    Longaker, M.T.3
  • 9
    • 77958089925 scopus 로고    scopus 로고
    • Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj
    • Wang S, Kawashima N, Sakamoto K, Katsube K, Umezawa A, Suda H. Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj. Biochem Biophys Res Commun 2010; 400(1): 39-45.
    • (2010) Biochem Biophys Res Commun , vol.400 , Issue.1 , pp. 39-45
    • Wang, S.1    Kawashima, N.2    Sakamoto, K.3    Katsube, K.4    Umezawa, A.5    Suda, H.6
  • 10
    • 73349110430 scopus 로고    scopus 로고
    • Wnt and PPAR gamma signaling in osteoblastogenesis and adipogenesis
    • Takada I, Kouzmenko AP, Kato S. Wnt and PPAR gamma signaling in osteoblastogenesis and adipogenesis. Nat Rev Rheumatol 2009; 5(8): 442-7.
    • (2009) Nat Rev Rheumatol , vol.5 , Issue.8 , pp. 442-447
    • Takada, I.1    Kouzmenko, A.P.2    Kato, S.3
  • 11
    • 65549165761 scopus 로고    scopus 로고
    • Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization
    • Christopher MJ, Liu F, Hilton MJ, Long F, Link DC. Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. Blood 2009; 114(7): 1331.
    • (2009) Blood , vol.114 , Issue.7 , pp. 1331
    • Christopher, M.J.1    Liu, F.2    Hilton, M.J.3    Long, F.4    Link, D.C.5
  • 12
    • 34249686005 scopus 로고    scopus 로고
    • Osteogenic differentiation of human marrow- derived mesenchymal stem cells
    • Marie PJ, Fromigué O. Osteogenic differentiation of human marrow- derived mesenchymal stem cells. Regenerative Med 2006; 1(4): 539-48.
    • (2006) Regenerative Med , vol.1 , Issue.4 , pp. 539-548
    • Marie, P.J.1    Fromigué, O.2
  • 13
    • 2942534119 scopus 로고    scopus 로고
    • Dexamethasone, BMP-2, and 1, 25-dihydroxyvitamin D enhance a more differentiated osteoblast phenotype: Validation of an in vitro model for human bone marrow-derived primary osteoblasts
    • Jørgensen NR, Henriksen Z, Sørensen OH, Civitelli R. Dexamethasone, BMP-2, and 1, 25-dihydroxyvitamin D enhance a more differentiated osteoblast phenotype: validation of an in vitro model for human bone marrow-derived primary osteoblasts. Steroids 2004; 69(4): 219-26.
    • (2004) Steroids , vol.69 , Issue.4 , pp. 219-226
    • Jørgensen, N.R.1    Henriksen, Z.2    Sørensen, O.H.3    Civitelli, R.4
  • 14
    • 4644369340 scopus 로고    scopus 로고
    • Menin is required for BMP-2- and TGF-$\beta$-regulated osteoblastic differentiation through interaction with Smads and Runx2
    • Sowa H, Kaji H, Hendy GN, et al. Menin is required for BMP-2- and TGF-$\beta$-regulated osteoblastic differentiation through interaction with Smads and Runx2. J Biol Chem 2004; 279(39): 40267-75.
    • (2004) J Biol Chem , vol.279 , Issue.39 , pp. 40267-40275
    • Sowa, H.1    Kaji, H.2    Hendy, G.N.3
  • 15
    • 33744979059 scopus 로고    scopus 로고
    • Epidermal growth factor as a candidate for ex vivo expansion of bone marrow- derived mesenchymal stem cells
    • Tamama K, Fan VH, Griffith LG, Blair HC, Wells A. Epidermal growth factor as a candidate for ex vivo expansion of bone marrow- derived mesenchymal stem cells. Stem Cells 2006; 24(3): 686-95.
    • (2006) Stem Cells , vol.24 , Issue.3 , pp. 686-695
    • Tamama, K.1    Fan, V.H.2    Griffith, L.G.3    Blair, H.C.4    Wells, A.5
  • 16
    • 34547925581 scopus 로고    scopus 로고
    • Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation
    • Baksh D, Boland GM, Tuan RS. Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. J cellular biochem 2007; 101(5): 1109-24.
    • (2007) J Cellular Biochem , vol.101 , Issue.5 , pp. 1109-1124
    • Baksh, D.1    Boland, G.M.2    Tuan, R.S.3
  • 17
    • 20344363684 scopus 로고    scopus 로고
    • Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation
    • Kratchmarova I, Blagoev B, Haack-Sorensen M, Kassem M, Mann M. Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science 2005; 308(5727): 1472-77.
    • (2005) Science , vol.308 , Issue.5727 , pp. 1472-1477
    • Kratchmarova, I.1    Blagoev, B.2    Haack-Sorensen, M.3    Kassem, M.4    Mann, M.5
  • 18
    • 77953632883 scopus 로고    scopus 로고
    • Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells
    • Hamidouche Z, Fromigué O, Nuber U, et al. Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells. J Cell Physiol 2010; 224(2): 509-15.
    • (2010) J Cell Physiol , vol.224 , Issue.2 , pp. 509-515
    • Hamidouche, Z.1    Fromigué, O.2    Nuber, U.3
  • 20
    • 0036205735 scopus 로고    scopus 로고
    • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
    • Ohbayashi N, Shibayama M, Kurotaki Y, et al. FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev 2002; 16(7): 870-9.
    • (2002) Genes Dev , vol.16 , Issue.7 , pp. 870-879
    • Ohbayashi, N.1    Shibayama, M.2    Kurotaki, Y.3
  • 21
    • 79953042169 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3α/β inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage
    • Gambardella A, Nagaraju CK, O'Shea PJ, et al. Glycogen synthase kinase-3α/β inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage. J Bone Miner Res 2011; 26(4): 811-21.
    • (2011) J Bone Miner Res , vol.26 , Issue.4 , pp. 811-821
    • Gambardella, A.1    Nagaraju, C.K.2    O'Shea, P.J.3
  • 22
    • 34548379522 scopus 로고    scopus 로고
    • Development of hybrid polymer scaffolds for potential applications in ligament and tendon tissue engineering
    • Sahoo S, Cho-Hong JG, Siew-Lok T. Development of hybrid polymer scaffolds for potential applications in ligament and tendon tissue engineering. Biomed Mater 2007; 2: 169.
    • (2007) Biomed Mater , vol.2 , pp. 169
    • Sahoo, S.1    Cho-Hong, J.G.2    Siew-Lok, T.3
  • 23
    • 67449143406 scopus 로고    scopus 로고
    • Composite tissue engineering on polycaprolactone nanofiber scaffolds
    • Reed CR, Han L, Andrady A, et al. Composite tissue engineering on polycaprolactone nanofiber scaffolds. Ann Plast Surg 2009; 62(5): 505-12.
    • (2009) Ann Plast Surg , vol.62 , Issue.5 , pp. 505-512
    • Reed, C.R.1    Han, L.2    Andrady, A.3
  • 24
    • 78650511385 scopus 로고    scopus 로고
    • Leukocyte common antigenrelated (LAR) tyrosine phosphatase positively regulates osteoblast differentiation by modulating extracellular signal-regulated kinase (ERK) activation
    • Kim WK, Bae KH, Choi HR, et al. Leukocyte common antigenrelated (LAR) tyrosine phosphatase positively regulates osteoblast differentiation by modulating extracellular signal-regulated kinase (ERK) activation. Mol Cells 2010; 30(4): 335-40.
    • (2010) Mol Cells , vol.30 , Issue.4 , pp. 335-340
    • Kim, W.K.1    Bae, K.H.2    Choi, H.R.3
  • 25
    • 70849131501 scopus 로고    scopus 로고
    • Regulation of adipogenic differentiation by LAR tyrosine phosphatase in human mesenchymal stem cells and 3T3-L1 preadipocytes
    • Kim WK, Jung H, Kim DH, et al. Regulation of adipogenic differentiation by LAR tyrosine phosphatase in human mesenchymal stem cells and 3T3-L1 preadipocytes. J Cell Sci 2009; 122(Pt 22): 4160-7.
    • (2009) J Cell Sci , vol.122 , Issue.PART 22 , pp. 4160-4167
    • Kim, W.K.1    Jung, H.2    Kim, D.H.3
  • 26
    • 0033624587 scopus 로고    scopus 로고
    • Overexpression of Delta FosB transcription factor (s) increases bone formation and inhibits adipogenesis
    • Sabatakos G, Sims NA, Chen J, et al. Overexpression of Delta FosB transcription factor (s) increases bone formation and inhibits adipogenesis. Nat Med 2000; 6(9): 985-90.
    • (2000) Nat Med , vol.6 , Issue.9 , pp. 985-990
    • Sabatakos, G.1    Sims, N.A.2    Chen, J.3
  • 27
  • 28
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006; 7(12): 885-96.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.12 , pp. 885-896
    • Rosen, E.D.1    Macdougald, O.A.2
  • 29
    • 34247116441 scopus 로고    scopus 로고
    • Physiological roles of PKB/Akt isoforms in development and disease
    • Dummler B, Hemmings B. Physiological roles of PKB/Akt isoforms in development and disease. Biochem Soc Trans 2007; 35: 231-5.
    • (2007) Biochem Soc Trans , vol.35 , pp. 231-235
    • Dummler, B.1    Hemmings, B.2
  • 30
    • 79953000714 scopus 로고    scopus 로고
    • Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment
    • Quach JM, Walker EC, Allan E, et al. Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment. J Biol Chem 2011; 286(6): 4186-98.
    • (2011) J Biol Chem , vol.286 , Issue.6 , pp. 4186-4198
    • Quach, J.M.1    Walker, E.C.2    Allan, E.3
  • 31
    • 84857748428 scopus 로고    scopus 로고
    • Role of TRX 1 and TRX2 on proliferation of human adipose tissue-derived mesenchymal stem cells
    • [Internet], Available from
    • Song JS, Cho HH, Lee B, Bae YC, Jung JS. Role of TRX 1 and TRX2 on proliferation of human adipose tissue-derived mesenchymal stem cells. Stem Cells Dev [Internet] 2010; Available from: http://www.ncbi.nlm.nih.gov/pubmed/21158569
    • (2010) Stem Cells Dev
    • Song, J.S.1    Cho, H.H.2    Lee, B.3    Bae, Y.C.4    Jung, J.S.5
  • 32
    • 41949118433 scopus 로고    scopus 로고
    • Regulation of mesenchymal stem cell osteogenic differentiation by glucocorticoid-induced leucine zipper (GILZ)
    • Zhang W, Yang N, Shi XM. Regulation of mesenchymal stem cell osteogenic differentiation by glucocorticoid-induced leucine zipper (GILZ). J Biol Chem 2008; 283(8): 4723.
    • (2008) J Biol Chem , vol.283 , Issue.8 , pp. 4723
    • Zhang, W.1    Yang, N.2    Shi, X.M.3
  • 33
    • 0033573897 scopus 로고    scopus 로고
    • Role of calpain in adipocyte differentiation
    • Patel YM, Lane MD. Role of calpain in adipocyte differentiation. Proc Natl Acad Sci USA 1999; 96(4): 1279-84.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.4 , pp. 1279-1284
    • Patel, Y.M.1    Lane, M.D.2
  • 34
    • 77955652947 scopus 로고    scopus 로고
    • Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution
    • Youm Y, Yang H, Amin R, Smith SR, Leff T, Dixit VD. Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution. Aging Cell 2010; 9(4): 478-89.
    • (2010) Aging Cell , vol.9 , Issue.4 , pp. 478-489
    • Youm, Y.1    Yang, H.2    Amin, R.3    Smith, S.R.4    Leff, T.5    Dixit, V.D.6
  • 35
    • 33746987081 scopus 로고    scopus 로고
    • The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling
    • Zhao M, Qiao M, Harris SE, Chen D, Oyajobi BO, Mundy GR. The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Mol cell biol 2006; 26(16): 6197.
    • (2006) Mol Cell Biol , vol.26 , Issue.16 , pp. 6197
    • Zhao, M.1    Qiao, M.2    Harris, S.E.3    Chen, D.4    Oyajobi, B.O.5    Mundy, G.R.6
  • 37
    • 77955163096 scopus 로고    scopus 로고
    • A clinically relevant model of osteoinduction: A process requiring calcium phosphate and BMP/Wnt signalling
    • Eyckmans J, Roberts SJ, Schrooten J, Luyten FP. A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling. J Cell Mol Med 2010; 14(6b): 1845-56.
    • (2010) J Cell Mol Med , vol.14 , Issue.6 b , pp. 1845-1856
    • Eyckmans, J.1    Roberts, S.J.2    Schrooten, J.3    Luyten, F.P.4
  • 38
    • 78650665733 scopus 로고    scopus 로고
    • Arkadia -- Beyond the TGF-{beta} pathway
    • [Internet], Nov 25 [cited 2010 Dec 19]; Available from
    • Miyazono K, Koinuma D. Arkadia -- Beyond the TGF-{beta} pathway. J. Biochem [Internet]. 2010 Nov 25 [cited 2010 Dec 19]; Available from: http://dx.doi.org/10.1093/jb/mvq133
    • (2010) J. Biochem.
    • Miyazono, K.1    Koinuma, D.2
  • 39
    • 0035988715 scopus 로고    scopus 로고
    • Bone morphogenetic proteins-2,-12, and-13 modulate in vitro development of engineered cartilage
    • Gooch KJ, Blunk T, Courter DL, Sieminski AL, Vunjak- Novakovic G, Freed LE. Bone morphogenetic proteins-2,-12, and-13 modulate in vitro development of engineered cartilage. Tissue Eng 2002; 8(4): 591-601.
    • (2002) Tissue Eng , vol.8 , Issue.4 , pp. 591-601
    • Gooch, K.J.1    Blunk, T.2    Courter, D.L.3    Sieminski, A.L.4    Vunjak-Novakovic, G.5    Freed, L.E.6
  • 40
    • 0035698442 scopus 로고    scopus 로고
    • BMP-6 accelerates both chondrogenesis and mineral maturation in differentiating chick limb-bud mesenchymal cell cultures
    • Boskey AL, Paschalis EP, Binderman I, Doty SB. BMP-6 accelerates both chondrogenesis and mineral maturation in differentiating chick limb-bud mesenchymal cell cultures. J cell biochem 2002; 84(3): 509-19.
    • (2002) J Cell Biochem , vol.84 , Issue.3 , pp. 509-519
    • Boskey, A.L.1    Paschalis, E.P.2    Binderman, I.3    Doty, S.B.4
  • 41
    • 0033025281 scopus 로고    scopus 로고
    • Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures
    • Denker AE, Haas AR, Nicoll SB, Tuan RS. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures. Differentiation 1999; 64(2): 67-76.
    • (1999) Differentiation , vol.64 , Issue.2 , pp. 67-76
    • Denker, A.E.1    Haas, A.R.2    Nicoll, S.B.3    Tuan, R.S.4
  • 42
    • 0035527591 scopus 로고    scopus 로고
    • Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells
    • Prockop DJ, Sekiya I, Colter DC. Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells. Cytotherapy 2001; 3(5): 393-6.
    • (2001) Cytotherapy , vol.3 , Issue.5 , pp. 393-396
    • Prockop, D.J.1    Sekiya, I.2    Colter, D.C.3
  • 43
    • 18844447203 scopus 로고    scopus 로고
    • Comparison of effect of BMP-2,-4, and-6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma
    • Sekiya I, Larson BL, Vuoristo JT, Reger RL, Prockop DJ. Comparison of effect of BMP-2,-4, and-6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma. Cell Tissue Res 2005; 320(2): 269-6.
    • (2005) Cell Tissue Res , vol.320 , Issue.2 , pp. 266-269
    • Sekiya, I.1    Larson, B.L.2    Vuoristo, J.T.3    Reger, R.L.4    Prockop, D.J.5
  • 44
    • 36448936383 scopus 로고    scopus 로고
    • TGF$\beta$-SMAD signal transduction: Molecular specificity and functional flexibility
    • Schmierer B, Hill CS. TGF$\beta$-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 2007; 8(12): 970-82.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.12 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 46
    • 77749273807 scopus 로고    scopus 로고
    • Activation of epidermal growth factor receptor gene is involved in transforming growth factor- beta-mediated fibronectin expression in a chondrocyte progenitor cell line
    • Takeda H, Inoue H, Kutsuna T, et al. Activation of epidermal growth factor receptor gene is involved in transforming growth factor- beta-mediated fibronectin expression in a chondrocyte progenitor cell line. Int J Mol Med 2010; 25(4): 593-600.
    • (2010) Int J Mol Med , vol.25 , Issue.4 , pp. 593-600
    • Takeda, H.1    Inoue, H.2    Kutsuna, T.3
  • 47
    • 0028126646 scopus 로고
    • Cartilage-derived morphogenetic proteins. New members of the transforming growth factorbeta superfamily predominantly expressed in long bones during human embryonic development
    • Chang SC, Hoang B, Thomas JT, et al. Cartilage-derived morphogenetic proteins. New members of the transforming growth factorbeta superfamily predominantly expressed in long bones during human embryonic development. J Biol Chem 1994; 269(45): 28227.
    • (1994) J Biol Chem , vol.269 , Issue.45 , pp. 28227
    • Chang, S.C.1    Hoang, B.2    Thomas, J.T.3
  • 48
    • 77951458865 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions
    • Khan WS, Adesida AB, Tew SR, Lowe ET, Hardingham TE. Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions. J Orthop Res 2010; 28(6): 834-40.
    • (2010) J Orthop Res , vol.28 , Issue.6 , pp. 834-840
    • Khan, W.S.1    Adesida, A.B.2    Tew, S.R.3    Lowe, E.T.4    Hardingham, T.E.5
  • 49
    • 34347206376 scopus 로고    scopus 로고
    • Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients
    • Khan WS, Adesida AB, Hardingham TE. Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients. Arthritis Res Ther 2007; 9(3): R55.
    • (2007) Arthritis Res Ther , vol.9 , Issue.3
    • Khan, W.S.1    Adesida, A.B.2    Hardingham, T.E.3
  • 50
    • 48249127947 scopus 로고    scopus 로고
    • Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2
    • Khan WS, Tew SR, Adesida AB, Hardingham TE. Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2. Arthritis Res Ther 2008; 10(4): R74.
    • (2008) Arthritis Res Ther , vol.10 , Issue.4
    • Khan, W.S.1    Tew, S.R.2    Adesida, A.B.3    Hardingham, T.E.4
  • 51
    • 0026016355 scopus 로고
    • Towards understanding skeletal muscle regeneration
    • Grounds MD. Towards understanding skeletal muscle regeneration. Pathol. Res Pract 1991; 187(1): 1-22.
    • (1991) Pathol. Res Pract. , vol.187 , Issue.1 , pp. 1-22
    • Grounds, M.D.1
  • 52
    • 12144290852 scopus 로고    scopus 로고
    • Skeletal muscle differentiation potential of human adult bone marrow cells
    • Bossolasco P, Corti S, Strazzer S, et al. Skeletal muscle differentiation potential of human adult bone marrow cells. Exp Cell Res 2004; 295(1): 66-78.
    • (2004) Exp Cell Res , vol.295 , Issue.1 , pp. 66-78
    • Bossolasco, P.1    Corti, S.2    Strazzer, S.3
  • 53
    • 22044450950 scopus 로고    scopus 로고
    • Bone marrow stromal cells generate muscle cells and repair muscle degeneration
    • Dezawa M, Ishikawa H, Itokazu Y, et al. Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 2005; 309(5732): 314-7.
    • (2005) Science , vol.309 , Issue.5732 , pp. 314-317
    • Dezawa, M.1    Ishikawa, H.2    Itokazu, Y.3
  • 54
    • 0021747723 scopus 로고
    • 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: Evidence for regulatory genes controlling determination
    • Konieczny SF, Emerson CP. 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: evidence for regulatory genes controlling determination. Cell 1984; 38(3): 791-800.
    • (1984) Cell , vol.38 , Issue.3 , pp. 791-800
    • Konieczny, S.F.1    Emerson, C.P.2
  • 55
    • 33749185593 scopus 로고    scopus 로고
    • Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration
    • Chan J, O'Donoghue K, Gavina M, et al. Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration. Stem Cells 2006; 24(8): 1879-91.
    • (2006) Stem Cells , vol.24 , Issue.8 , pp. 1879-1891
    • Chan, J.1    O'Donoghue, K.2    Gavina, M.3
  • 56
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery C, Ward-van Oostwaard D, Doevendans P, et al. Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 2003; 107(21): 2733-40.
    • (2003) Circulation , vol.107 , Issue.21 , pp. 2733-2740
    • Mummery, C.1    Ward-Van oostwaard, D.2    Doevendans, P.3
  • 57
    • 85016530806 scopus 로고
    • Myogenic expression of mesenchymal stem cells within myotubes of mdx mice in vitro and in vivo
    • Saito T, Dennis JE, Lennon DP, Young RG, Caplan AI. Myogenic expression of mesenchymal stem cells within myotubes of mdx mice in vitro and in vivo. Tissue Eng 1995; 1(4): 327-43.
    • (1995) Tissue Eng , vol.1 , Issue.4 , pp. 327-343
    • Saito, T.1    Dennis, J.E.2    Lennon, D.P.3    Young, R.G.4    Caplan, A.I.5
  • 58
    • 42649130645 scopus 로고    scopus 로고
    • Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage
    • Gang EJ, Bosnakovski D, Simsek T, To K, Perlingeiro RC. Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage. Exp Cell Res 2008; 314(8): 1721-33.
    • (2008) Exp Cell Res , vol.314 , Issue.8 , pp. 1721-1733
    • Gang, E.J.1    Bosnakovski, D.2    Simsek, T.3    To, K.4    Perlingeiro, R.C.5
  • 59
    • 0028205049 scopus 로고
    • Regulation of Pax-3 expression in the dermomyotome and its role in muscle development
    • Goulding M, Lumsden A, Paquette AJ. Regulation of Pax-3 expression in the dermomyotome and its role in muscle development. Development 1994; 120(4): 957-1.
    • (1994) Development , vol.120 , Issue.4 , pp. 951-957
    • Goulding, M.1    Lumsden, A.2    Paquette, A.J.3
  • 60
    • 0035003070 scopus 로고    scopus 로고
    • Biocompatibility of NDGApolymerized collagen fibers. I. Evaluation of cytotoxicity with tendon fibroblasts in vitro
    • Koob TJ, Willis TA, Hernandez DJ. Biocompatibility of NDGApolymerized collagen fibers. I. Evaluation of cytotoxicity with tendon fibroblasts in vitro. J Biomed Mater Res 2001; 56(1): 31-9.
    • (2001) J Biomed Mater Res , vol.56 , Issue.1 , pp. 31-39
    • Koob, T.J.1    Willis, T.A.2    Hernandez, D.J.3
  • 61
    • 0017094381 scopus 로고
    • Maintenance of differentiation in primary cultures of avian tendon cells
    • Schwarz R, Colarusso L, Doty P. Maintenance of differentiation in primary cultures of avian tendon cells. Exp Cell Res 1976; 102(1): 63-71.
    • (1976) Exp Cell Res , vol.102 , Issue.1 , pp. 63-71
    • Schwarz, R.1    Colarusso, L.2    Doty, P.3
  • 62
    • 65549114268 scopus 로고    scopus 로고
    • Horse bone marrow mesenchymal stem cells express embryo stem cell markers and show the ability for tenogenic differentiation by in vitro exposure to BMP-12
    • Stefania V, Paola R, Chiara G, Paola M. Horse bone marrow mesenchymal stem cells express embryo stem cell markers and show the ability for tenogenic differentiation by in vitro exposure to BMP-12. BMC Cell Biol 2009; 10: 29.
    • (2009) BMC Cell Biol , vol.10 , pp. 29
    • Stefania, V.1    Paola, R.2    Chiara, G.3    Paola, M.4
  • 63
    • 31844456212 scopus 로고    scopus 로고
    • Mesenchymal stem cells differentiate into tenocytes by bone morphogenetic protein (BMP) 12 gene transfer
    • Wang QW, Chen ZL, Piao YJ. Mesenchymal stem cells differentiate into tenocytes by bone morphogenetic protein (BMP) 12 gene transfer. J Biosci Bioeng 2005; 100(4): 418-22.
    • (2005) J Biosci Bioeng , vol.100 , Issue.4 , pp. 418-422
    • Wang, Q.W.1    Chen, Z.L.2    Piao, Y.J.3
  • 64
    • 33748765254 scopus 로고    scopus 로고
    • Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes
    • Shukunami C, Takimoto A, Oro M, Hiraki Y. Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes. Dev Biol 2006; 298(1): 234-47.
    • (2006) Dev Biol , vol.298 , Issue.1 , pp. 234-247
    • Shukunami, C.1    Takimoto, A.2    Oro, M.3    Hiraki, Y.4
  • 65
    • 48849083314 scopus 로고    scopus 로고
    • The effects of GDF-5 and uniaxial strain on mesenchymal stem cells in 3-D culture
    • Farng E, Urdaneta AR, Barba D, Esmende S, McAllister DR. The effects of GDF-5 and uniaxial strain on mesenchymal stem cells in 3-D culture. Clin Orthop Relat Res 2008; 466(8): 1930-7.
    • (2008) Clin Orthop Relat Res , vol.466 , Issue.8 , pp. 1930-1937
    • Farng, E.1    Urdaneta, A.R.2    Barba, D.3    Esmende, S.4    McAllister, D.R.5
  • 66
    • 33645529161 scopus 로고    scopus 로고
    • Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells
    • Hoffmann A, Pelled G, Turgeman G, et al. Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells. J Clin Invest 2006; 116(4): 940-52.
    • (2006) J Clin Invest , vol.116 , Issue.4 , pp. 940-952
    • Hoffmann, A.1    Pelled, G.2    Turgeman, G.3
  • 67
    • 70349999453 scopus 로고    scopus 로고
    • Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells
    • Luo Q, Song G, Song Y, Xu B, Qin J, Shi Y. Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells. Cytotechnology 2009; 61(1): 1-10.
    • (2009) Cytotechnology , vol.61 , Issue.1 , pp. 1-10
    • Luo, Q.1    Song, G.2    Song, Y.3    Xu, B.4    Qin, J.5    Shi, Y.6
  • 68
    • 0034040008 scopus 로고    scopus 로고
    • In vitro characterization of mesenchymal stem cell-seeded collagen scaffolds for tendon repair: Effects of initial seeding density on contraction kinetics
    • Awad HA, Butler DL, Harris MT, et al. In vitro characterization of mesenchymal stem cell-seeded collagen scaffolds for tendon repair: effects of initial seeding density on contraction kinetics. J Biomed Mater Research Part A 2000; 51(2): 233-40.
    • (2000) J Biomed Mater Research Part A , vol.51 , Issue.2 , pp. 233-240
    • Awad, H.A.1    Butler, D.L.2    Harris, M.T.3
  • 69
    • 53049090671 scopus 로고    scopus 로고
    • Mechanoactive tenogenic differentiation of human mesenchymal stem cells
    • Kuo CK, Tuan RS. Mechanoactive tenogenic differentiation of human mesenchymal stem cells. Tissue Eng Part A 2008; 14(10): 1615-27.
    • (2008) Tissue Eng Part A , vol.14 , Issue.10 , pp. 1615-1627
    • Kuo, C.K.1    Tuan, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.