Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase

International Journal of Oncology

Volumn 12, Issue 1, 1998, Pages 37-44

  Dadras, Soheil S ^a   Thorgeirsson, Snorri S ^b   Rao, M Sambasiva ^a   Reddy, Janardan K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; Fatty acyl CoA oxidase; H2O2; Oxidative damage; Peroxisome; Transformation

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; HYDROGEN PEROXIDE; 15 TETRACOSENOIC ACID; ACYL COENZYME A OXIDASE; ERUCIC ACID; LINOLEIC ACID; MONOUNSATURATED FATTY ACID; OXIDOREDUCTASE; PRIMER DNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL IMMORTALIZATION; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME INDUCTION; FIBROSARCOMA; LIPID PEROXIDATION; MALIGNANT TRANSFORMATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CELL TRANSFORMATION; CLONOGENIC ASSAY; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION; MALE; METABOLISM; NICK END LABELING; NORTHERN BLOTTING; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RAT; WESTERN BLOTTING;

ACYL-COA OXIDASE; ANIMALS; APOPTOSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; DNA PRIMERS; ERUCIC ACIDS; FATTY ACIDS, MONOUNSATURATED; FIBROBLASTS; FIBROSARCOMA; GENE EXPRESSION; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LINOLEIC ACID; MALE; MICE; MICE, NUDE; OXIDOREDUCTASES; POLYMERASE CHAIN REACTION; RATS;

EID: 0031974273     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.12.1.37     Document Type: Article

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