CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  Matullo, Christine M ^a,b   O'Regan, Kevin J ^a   Curtis, Mark ^b   Rall, Glenn F ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HERNIA; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; EX VIVO STUDY; IMMUNOCOMPETENT CELL; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOCYTIC INFILTRATION; MEASLES VIRUS; MIXED INFECTION; MOUSE; NEUROPATHOLOGY; NONHUMAN; SEIZURE; TRANSGENIC MOUSE; VIRUS INFECTION; ANIMAL; BRAIN; BRAIN EDEMA; CELL MOTION; GENETICS; HUMAN; IMMUNOLOGY; LYMPHOCYTIC CHORIOMENINGITIS; MEASLES; METABOLISM; MOUSE MUTANT; PATHOLOGY; VIROLOGY;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEASLES VIRUS; MUS; MUS MUSCULUS;

ANIMALS; BRAIN; BRAIN EDEMA; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; HUMANS; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEASLES; MEASLES VIRUS; MICE; MICE, KNOCKOUT;

EID: 84855257652     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002462     Document Type: Article

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