Two patterns of thrombopoietin signaling suggest no coupling between platelet production and thrombopoietin reactivity in thrombocytopenia-absent radii syndrome

Haematologica

Volumn 97, Issue 1, 2012, Pages 73-81

  Fiedler, Janine ^a,b   Strauß, Gabriele ^b   Wannack, Martin ^b   Schwiebert, Silke ^b   Seidel, Kerstin ^b   Henning, Katja ^b   Klopocki, Eva ^b   Schmugge, Markus ^c   Gaedicke, Gerhard ^b   Schulze, Harald ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

Platelets; Therapy; Thrombocytopenia absent radii syndrome; Thrombopoietin

Indexed keywords

ALPHA2 INTEGRIN; ALPHA6 INTEGRIN; BETA1 INTEGRIN; CD42A ANTIGEN; COMPLEMENTARY DNA; FIBRINOGEN RECEPTOR; FIBRONECTIN RECEPTOR; GLYCOPROTEIN IB ALPHA; INTEGRIN RECEPTOR; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE TYK2; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; THROMBIN RECEPTOR; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGE; ARTICLE; CHILD; CLINICAL ARTICLE; CORRELATION ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME RELEASE; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; INFANT; LYSOSOME; MALE; PRESCHOOL CHILD; PROTEIN EXPRESSION; SCHOOL CHILD; SIGNAL TRANSDUCTION; SYNDROME; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOCYTOPENIA; THROMBOCYTOPENIA WITH ABSENT RADII SYNDROME; THROMBOCYTOPOIESIS;

ADOLESCENT; ADULT; AGE FACTORS; BLOOD PLATELETS; CELL LINE; CHILD; CHILD, PRESCHOOL; CHROMOSOME DELETION; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MEGAKARYOCYTES; PLATELET COUNT; RADIUS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; THROMBOPOIETIN; UPPER EXTREMITY DEFORMITIES, CONGENITAL; YOUNG ADULT;

EID: 84855245414     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.049619     Document Type: Article

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