-
1
-
-
69149097969
-
Cannabinoid receptor ligands as potential anticancer agents - High hopes for new therapies?
-
Oesch S, Gertsch J. 2009; Cannabinoid receptor ligands as potential anticancer agents - High hopes for new therapies? J Pharm Pharmacol 61: 839-853.
-
(2009)
J Pharm Pharmacol
, vol.61
, pp. 839-853
-
-
Oesch, S.1
Gertsch, J.2
-
2
-
-
63349100859
-
CB(2) cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion
-
Montecucco F, Lenglet S, Braunersreuther V, et al. 2009; CB(2) cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion. J Mol Cell Cardiol 46: 612-620.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 612-620
-
-
Montecucco, F.1
Lenglet, S.2
Braunersreuther, V.3
-
3
-
-
0027444581
-
Antinociceptive actions of cannabinoids following intraventricular administration in rats
-
Martin WJ, Lai NK, Patrick SL, Tsou K, Walker JM. 1993; Antinociceptive actions of cannabinoids following intraventricular administration in rats. Brain Res 629: 300-304.
-
(1993)
Brain Res
, vol.629
, pp. 300-304
-
-
Martin, W.J.1
Lai, N.K.2
Patrick, S.L.3
Tsou, K.4
Walker, J.M.5
-
4
-
-
0031834745
-
'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: Biochemistry and possible physiopathological relevance
-
Di MV. 1998; 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: Biochemistry and possible physiopathological relevance. Biochim Biophys Acta 1392: 153-175.
-
(1998)
Biochim Biophys Acta
, vol.1392
, pp. 153-175
-
-
Di, M.V.1
-
5
-
-
0033405883
-
Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells
-
Melck D, Rueda D, Galve-Roperh I, De PL, Guzman M, Di MV. 1999; Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett 463: 235-240.
-
(1999)
FEBS Lett
, vol.463
, pp. 235-240
-
-
Melck, D.1
Rueda, D.2
Galve-Roperh, I.3
De, P.L.4
Guzman, M.5
Di, M.V.6
-
6
-
-
0034654660
-
The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt
-
Gomez del PT, Velasco G, Guzman M. 2000; The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. Biochem J 347: 369-373.
-
(2000)
Biochem J
, vol.347
, pp. 369-373
-
-
Gomez del, P.T.1
Velasco, G.2
Guzman, M.3
-
7
-
-
40649102938
-
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
-
Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K. 2008; GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci USA 105: 2699-2704.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2699-2704
-
-
Lauckner, J.E.1
Jensen, J.B.2
Chen, H.Y.3
Lu, H.C.4
Hille, B.5
Mackie, K.6
-
8
-
-
2342590653
-
Multiple actions of anandamide on neonatal rat cultured sensory neurones
-
Evans RM, Scott RH, Ross RA. 2004; Multiple actions of anandamide on neonatal rat cultured sensory neurones. Br J Pharmacol 141: 1223-1233.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 1223-1233
-
-
Evans, R.M.1
Scott, R.H.2
Ross, R.A.3
-
9
-
-
0029904838
-
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
-
Cravatt BF, Giang DK, Mayfield SP, Boger DL, Lerner RA, Gilula NB. 1996; Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384: 83-87.
-
(1996)
Nature
, vol.384
, pp. 83-87
-
-
Cravatt, B.F.1
Giang, D.K.2
Mayfield, S.P.3
Boger, D.L.4
Lerner, R.A.5
Gilula, N.B.6
-
10
-
-
0034644769
-
Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors
-
Maccarrone M, Lorenzon T, Bari M, Melino G, Finazzi-Agro A. 2000; Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J Biol Chem 275: 31938-31945.
-
(2000)
J Biol Chem
, vol.275
, pp. 31938-31945
-
-
Maccarrone, M.1
Lorenzon, T.2
Bari, M.3
Melino, G.4
Finazzi-Agro, A.5
-
11
-
-
70350350039
-
Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis
-
Pasquariello N, Catanzaro G, Marzano V, et al. 2009; Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. J Biol Chem 284: 29413-29426.
-
(2009)
J Biol Chem
, vol.284
, pp. 29413-29426
-
-
Pasquariello, N.1
Catanzaro, G.2
Marzano, V.3
-
12
-
-
0037253496
-
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
-
Casanova ML, Blazquez C, Martinez-Palacio J, et al. 2003; Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 111: 43-50.
-
(2003)
J Clin Invest
, vol.111
, pp. 43-50
-
-
Casanova, M.L.1
Blazquez, C.2
Martinez-Palacio, J.3
-
13
-
-
33744542391
-
Fatty acid amide hydrolase determines anandamide-induced cell death in the liver
-
Siegmund SV, Seki E, Osawa Y, Uchinami H, Cravatt BF, Schwabe RF. 2006; Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. J Biol Chem 281: 10431-10438.
-
(2006)
J Biol Chem
, vol.281
, pp. 10431-10438
-
-
Siegmund, S.V.1
Seki, E.2
Osawa, Y.3
Uchinami, H.4
Cravatt, B.F.5
Schwabe, R.F.6
-
14
-
-
9444280832
-
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation
-
Bifulco M, Laezza C, Valenti M, Ligresti A, Portella G, Di MV. 2004; A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. FASEB J 18: 1606-1608.
-
(2004)
FASEB J
, vol.18
, pp. 1606-1608
-
-
Bifulco, M.1
Laezza, C.2
Valenti, M.3
Ligresti, A.4
Portella, G.5
Di, M.V.6
-
15
-
-
34250378332
-
Opposing actions of endocannabinoids on cholangiocarcinoma growth: Recruitment of Fas and Fas ligand to lipid rafts
-
DeMorrow S, Glaser S, Francis H, et al. 2007; Opposing actions of endocannabinoids on cholangiocarcinoma growth: Recruitment of Fas and Fas ligand to lipid rafts. J Biol Chem 282: 13098-13113.
-
(2007)
J Biol Chem
, vol.282
, pp. 13098-13113
-
-
DeMorrow, S.1
Glaser, S.2
Francis, H.3
-
16
-
-
77953211523
-
The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells
-
Patsos HA, Greenhough A, Hicks DJ, et al. 2010; The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. Int J Oncol 37: 187-193.
-
(2010)
Int J Oncol
, vol.37
, pp. 187-193
-
-
Patsos, H.A.1
Greenhough, A.2
Hicks, D.J.3
-
17
-
-
0037160078
-
Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides
-
Kozak KR, Crews BC, Morrow JD, et al. 2002; Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277: 44877-44885.
-
(2002)
J Biol Chem
, vol.277
, pp. 44877-44885
-
-
Kozak, K.R.1
Crews, B.C.2
Morrow, J.D.3
-
18
-
-
0030611859
-
Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2
-
Yu M, Ives D, Ramesha CS. 1997; Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. J Biol Chem 272: 21181-21186.
-
(1997)
J Biol Chem
, vol.272
, pp. 21181-21186
-
-
Yu, M.1
Ives, D.2
Ramesha, C.S.3
-
19
-
-
68849119019
-
Metabolism of anandamide by COX-2 Is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes
-
Van Dross RT. 2009; Metabolism of anandamide by COX-2 Is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. Mol Carcinog 48: 724-732.
-
(2009)
Mol Carcinog
, vol.48
, pp. 724-732
-
-
Van Dross, R.T.1
-
20
-
-
28144431771
-
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2
-
Patsos HA, Hicks DJ, Dobson RR, et al. 2005; The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2. Gut 54: 1741-1750.
-
(2005)
Gut
, vol.54
, pp. 1741-1750
-
-
Patsos, H.A.1
Hicks, D.J.2
Dobson, R.R.3
-
21
-
-
58549110631
-
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway
-
Eichele K, Ramer R, Hinz B. 2009; R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. Pharm Res 26: 346-355.
-
(2009)
Pharm Res
, vol.26
, pp. 346-355
-
-
Eichele, K.1
Ramer, R.2
Hinz, B.3
-
22
-
-
0020464736
-
9-deoxy-delta 9-prostaglandin D2, a prostaglandin D2 derivative with potent antineoplastic and weak smooth muscle-contracting activities
-
Fukushima M, Kato T, Ota K, Arai Y, Narumiya S, Hayaishi O. 1982; 9-deoxy-delta 9-prostaglandin D2, a prostaglandin D2 derivative with potent antineoplastic and weak smooth muscle-contracting activities. Biochem Biophys Res Commun 109: 626-633.
-
(1982)
Biochem Biophys Res Commun
, vol.109
, pp. 626-633
-
-
Fukushima, M.1
Kato, T.2
Ota, K.3
Arai, Y.4
Narumiya, S.5
Hayaishi, O.6
-
23
-
-
38949126129
-
15-Deoxy-delta(12,14)-prostaglandin J2: An electrophilic trigger of cellular responses
-
Uchida K, Shibata T. 2007; 15-Deoxy-delta(12, 14)-prostaglandin J2: An electrophilic trigger of cellular responses. Chem Res Toxicol 21: 138-144.
-
(2007)
Chem Res Toxicol
, vol.21
, pp. 138-144
-
-
Uchida, K.1
Shibata, T.2
-
24
-
-
70349440955
-
15-Deoxi-Delta(12,14)-prostaglandin J(2) is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest
-
Cocca C, Dorado J, Calvo E, Lopez JA, Santos A, Perez-Castillo A. 2009; 15-Deoxi-Delta(12, 14)-prostaglandin J(2) is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. Biochem Pharmacol 78: 1330-1339.
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1330-1339
-
-
Cocca, C.1
Dorado, J.2
Calvo, E.3
Lopez, J.A.4
Santos, A.5
Perez-Castillo, A.6
-
25
-
-
17444363390
-
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species
-
Chen YC, Shen SC, Tsai SH. 2005; Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. Biochim Biophys Acta 1743: 291-304.
-
(2005)
Biochim Biophys Acta
, vol.1743
, pp. 291-304
-
-
Chen, Y.C.1
Shen, S.C.2
Tsai, S.H.3
-
26
-
-
0037096205
-
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism
-
Ward C, Dransfield I, Murray J, Farrow SN, Haslett C, Rossi AG. 2002; Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. J Immunol 168: 6232-6243.
-
(2002)
J Immunol
, vol.168
, pp. 6232-6243
-
-
Ward, C.1
Dransfield, I.2
Murray, J.3
Farrow, S.N.4
Haslett, C.5
Rossi, A.G.6
-
27
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. 2010; Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
28
-
-
0035853707
-
Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress
-
Kondo M, Oya-Ito T, Kumagai T, Osawa T, Uchida K. 2001; Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress. J Biol Chem 276: 12076-12083.
-
(2001)
J Biol Chem
, vol.276
, pp. 12076-12083
-
-
Kondo, M.1
Oya-Ito, T.2
Kumagai, T.3
Osawa, T.4
Uchida, K.5
-
29
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T, Itoh K, Takahashi S, et al. 2000; Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275: 16023-16029.
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
-
30
-
-
1642547042
-
Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry
-
Weber A, Ni J, Ling KH, et al. 2004; Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. J Lipid Res 45: 757-763.
-
(2004)
J Lipid Res
, vol.45
, pp. 757-763
-
-
Weber, A.1
Ni, J.2
Ling, K.H.3
-
31
-
-
84855235278
-
-
Drugs Used in the Treatment of Gastrointestinal Diseases.
-
McQuaid Kenneth R. 2010; Drugs Used in the Treatment of Gastrointestinal Diseases.
-
(2010)
-
-
McQuaid Kenneth, R.1
-
32
-
-
84855235277
-
-
Health Canada Drug Product Database. Ref Type: Generic.
-
Health Canada Drug Product Database. 2010; Ref Type: Generic.
-
(2010)
-
-
-
33
-
-
51649093696
-
The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products
-
Woodward DF, Carling RW, Cornell CL, et al. 2008; The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products. Pharmacol Ther 120: 71-80.
-
(2008)
Pharmacol Ther
, vol.120
, pp. 71-80
-
-
Woodward, D.F.1
Carling, R.W.2
Cornell, C.L.3
-
34
-
-
85048182106
-
Rimonabant: Obituary for a wonder drug
-
Boekholdt SM, Peters RJ. 2010; Rimonabant: Obituary for a wonder drug. Lancet 376: 489-490.
-
(2010)
Lancet
, vol.376
, pp. 489-490
-
-
Boekholdt, S.M.1
Peters, R.J.2
-
35
-
-
9444229367
-
Up-regulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells
-
Hinz B, Ramer R, Eichele K, Weinzierl U, Brune K. 2004; Up-regulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells. Mol Pharmacol 66: 1643-1651.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1643-1651
-
-
Hinz, B.1
Ramer, R.2
Eichele, K.3
Weinzierl, U.4
Brune, K.5
-
36
-
-
11144356025
-
Prostaglandin ethanolamides (prostamides): In vitro pharmacology and metabolism
-
Matias I, Chen J, De PL, et al. 2004; Prostaglandin ethanolamides (prostamides): In vitro pharmacology and metabolism. J Pharmacol Exp Ther 309: 745-757.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 745-757
-
-
Matias, I.1
Chen, J.2
De, P.L.3
-
37
-
-
33751161701
-
Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: Role of the IkappaB kinase/nuclear factor-kappaB pathway
-
Ciucci A, Gianferretti P, Piva R, et al. 2006; Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: Role of the IkappaB kinase/nuclear factor-kappaB pathway. Mol Pharmacol 70: 1812-1821.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1812-1821
-
-
Ciucci, A.1
Gianferretti, P.2
Piva, R.3
-
38
-
-
0032884254
-
Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells
-
Clay CE, Namen AM, Atsumi G, et al. 1999; Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells. Carcinogenesis 20: 1905-1911.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1905-1911
-
-
Clay, C.E.1
Namen, A.M.2
Atsumi, G.3
-
39
-
-
31544451531
-
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis
-
Millan O, Rico D, Peinado H, et al. 2006; Potentiation of tumor formation by topical administration of 15-deoxy-delta12, 14-prostaglandin J2 in a model of skin carcinogenesis. Carcinogenesis 27: 328-336.
-
(2006)
Carcinogenesis
, vol.27
, pp. 328-336
-
-
Millan, O.1
Rico, D.2
Peinado, H.3
-
40
-
-
0035572856
-
Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells
-
Levonen AL, Dickinson DA, Moellering DR, Mulcahy RT, Forman HJ, rley-Usmar VM. 2001; Biphasic effects of 15-deoxy-delta(12, 14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. Arterioscler Thromb Vasc Biol 21: 1846-1851.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1846-1851
-
-
Levonen, A.L.1
Dickinson, D.A.2
Moellering, D.R.3
Mulcahy, R.T.4
Forman, H.J.5
rley-Usmar, V.M.6
-
41
-
-
77956625655
-
TRPV1 splice variants: Structure and function
-
Schumacher MA, Eilers H. 2010; TRPV1 splice variants: Structure and function. Front Biosci 15: 872-882.
-
(2010)
Front Biosci
, vol.15
, pp. 872-882
-
-
Schumacher, M.A.1
Eilers, H.2
|