Modification of the adenoviral transfer vector enhances expression of the Hantavirus fusion protein GnS0.7 and induces a strong immune response in C57BL/6 mice

Journal of Virological Methods

Volumn 179, Issue 1, 2012, Pages 90-96

  Li, Pu Yuan ^a   Yu, Lan ^a   Wu, Xing An ^a   Bai, Wen Tao ^b   Li, Kai ^a   Wang, Hai Tao ^a   Hu, Gang ^a   Zhang, Liang ^a   Zhang, Fang Lin ^a   Xu, Zhi Kai ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Adenovirus expression system; Fusion protein; Hantavirus; Immunogenicity; Modified vectors

Indexed keywords

ADENOVIRUS VECTOR; HANTAVIRUS FUSION PROTEIN GNSO.7; HEMORRHAGIC FEVER WITH RENAL SYNDROME VACCINE; UNCLASSIFIED DRUG; VACCINE; VIRUS FUSION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CAG PROMOTER; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA MODIFICATION; ENHANCER REGION; FEMALE; HANTAVIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOASSAY; IMMUNOGENICITY; IMMUNOPOTENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY SEQUENCE; VIRUS RECOMBINANT; WOODCHUCK HEPATITIS VIRUS POST TRANSCRIPTIONAL REGULATORY ELEMENT;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; DRUG CARRIERS; FEMALE; GENETIC VECTORS; HANTAVIRUS; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; RECOMBINANT FUSION PROTEINS; VIRAL VACCINES;

ADENOVIRIDAE; ANIMALIA; HANTAAN VIRUS; HANTAVIRUS; MUS; WOODCHUCK HEPATITIS VIRUS;

EID: 84855231917     PISSN: 01660934     EISSN: 18790984     Source Type: Journal    
DOI: 10.1016/j.jviromet.2011.10.005     Document Type: Article

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