SM22α-induced activation of p16INK4a/retinoblastoma pathway promotes cellular senescence caused by a subclinical dose of γ-radiation and doxorubicin in HepG2 cells

Biochemical and Biophysical Research Communications

Volumn 400, Issue 1, 2010, Pages 100-105

  Kim, Tae Rim ^a   Lee, Hee Min ^a   Lee, So Yong ^a   Kim, Eun Jin ^a   Kim, Kug Chan ^a   Paik, Sang Gi ^b   Cho, Eun Wie ^c   Kim, In Gyu ^a  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Radiation; Cell growth arrest; Retinoblastoma protein; Senescence; SM22

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DOXORUBICIN; METALLOTHIONEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSGELIN; ACTIN BINDING PROTEIN; ANTINEOPLASTIC ANTIBIOTIC; MT1G PROTEIN, HUMAN; MUSCLE PROTEIN;

ARTICLE; CELL AGING; CELL GROWTH; CELL STRAIN HEPG2; CONTROLLED STUDY; GAMMA RADIATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; GENETICS; METABOLISM; TUMOR CELL LINE;

ANTIBIOTICS, ANTINEOPLASTIC; CELL AGING; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DOXORUBICIN; GAMMA RAYS; HUMANS; METALLOTHIONEIN; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; RETINOBLASTOMA PROTEIN;

EID: 84755161725     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.08.018     Document Type: Article

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