Influence of lipid components on gene delivery by polycation liposomes: Transfection efficiency, intracellular kinetics and in vivo tumor inhibition

International Journal of Pharmaceutics

Volumn 422, Issue 1-2, 2012, Pages 510-515

  Chen, Jinliang ^a   Sun, Xiaoyi ^b   Yu, Zhenwei ^c   Gao, Jianqing ^d   Liang, Wenquan ^d  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

Intracellular trafficking; Lipid saturation; Polycation liposomes; Transfection efficiency; Tumor inhibition

Indexed keywords

LIPID; LIPOSOME; LUCIFERASE; OLIGONUCLEOTIDE; PHOSPHOLIPID; POLYCATION; PROTAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL KINETICS; CELL LINE; CELL MIGRATION; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EGG; FEMALE; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INCUBATION TIME; LASER SCANNING CYTOMETRY; LIPID COMPOSITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOYBEAN;

ANIMALS; BIOLOGICAL TRANSPORT; CHOLESTEROL; FEMALE; FLOW CYTOMETRY; GENE THERAPY; HELA CELLS; HUMANS; INTERLEUKIN-12; KINETICS; LUCIFERASES; MICE; MICE, INBRED ICR; MICROSCOPY, CONFOCAL; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PHOSPHOLIPIDS; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; POLYETHYLENEIMINE; PROTAMINES; SARCOMA 180; TRANSFECTION; TUMOR BURDEN;

EID: 84655174965     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.11.024     Document Type: Article

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