Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats: Dose- and affinity-response relationships

Drug Metabolism and Disposition

Volumn 33, Issue 7, 2005, Pages 1056-1061

  Keyler, D E ^a,b   Roiko, S A ^a   Benlhabib, E ^a   LeSage, M G ^a   St Peter, J V ^b   Stewart, S ^d   Fuller, S ^d   Le, C T ^e   Pentel, P R ^a,c,f  

^a MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d Nabi Biopharmaceuticals   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f HENNEPIN COUNTY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NICOTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG HALF LIFE; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; MICE; NICOTINE; RABBITS; RATS;

ORYCTOLAGUS CUNICULUS;

EID: 22344435723     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.105.004234     Document Type: Article

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