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Volumn 21, Issue 1, 2012, Pages 7-14

Targeting cognitive deficits in schizophrenia: A review of the development of a new class of medicines from the perspective of community mental health researchers

Author keywords

Clinical trials; Cognitive deficits; Cognitive enhancing agents; Schizophrenia

Indexed keywords

ABT 288; DAVUNETIDE; DEXAMPHETAMINE; DRINABANT; EVP 6124; FARAMPATOR; GALANTAMINE; GSK 239512; ILLICIT DRUG; MK 0777; NEUROLEPTIC AGENT; OXYTOCIN; PF 3463275; PITOLISANT; PREGNENOLONE; QUETIAPINE; RISPERIDONE; RO 4917838; TC 5619; UNCLASSIFIED DRUG; ZICRONAPINE;

EID: 84555190297     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2012.634798     Document Type: Article
Times cited : (5)

References (40)
  • 2
    • 33644698983 scopus 로고    scopus 로고
    • WFSBP task force on treatment guidelines for schizophrenia: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia
    • Falkai P, Wobrock T, Lieberman J, et al. WFSBP task force on treatment guidelines for schizophrenia: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia. World J Biol Psychiatry 2005;21:132-91
    • (2005) World J Biol Psychiatry , vol.21 , pp. 132-191
    • Falkai, P.1    Wobrock, T.2    Lieberman, J.3
  • 4
    • 47249104675 scopus 로고    scopus 로고
    • The evolution of drug development in schizophrenia: Past issues and future opportunities
    • DOI 10.1038/sj.npp.1301639, PII 1301639
    • Carpenter W, Koenig JI. The evolution of drug development in schizophrenia: past issues and future opportunities. Neuropsychopharmacology 2008;33:2061-79 (Pubitemid 351992095)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.9 , pp. 2061-2079
    • Carpenter, W.T.1    Koenig, J.I.2
  • 5
    • 12344326514 scopus 로고    scopus 로고
    • Treatmentsforschizophrenia: Acriticalreviewofpharmacologyand mechanismsofactionofantipsychoticdrugs
    • MiyamotoS,DuncanGE,MarxCE, LiebermanJA.Treatmentsforschizophrenia: acriticalreviewofpharmacologyand mechanismsofactionofantipsychoticdrugs. MolPsychiatry2005;10:79-104
    • (2005) MolPsychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 6
    • 0038653525 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of second-generation antipsychotics
    • DOI 10.1001/archpsyc.60.6.553
    • Davis JM, Chen N, Glick ID. A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry 2003;60:553-64 (Pubitemid 36682312)
    • (2003) Archives of General Psychiatry , vol.60 , Issue.6 , pp. 553-564
    • Davis, J.M.1    Chen, N.2    Glick, I.D.3
  • 8
    • 0031903740 scopus 로고    scopus 로고
    • Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
    • DOI 10.1037/0894-4105.12.3.426
    • Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998;12:426-45 (Pubitemid 28323862)
    • (1998) Neuropsychology , vol.12 , Issue.3 , pp. 426-445
    • Heinrichs, R.W.1    Zakzanis, K.K.2
  • 9
    • 0029918481 scopus 로고    scopus 로고
    • What are the functional consequences of neurocognitive deficits in schizophrenia?
    • Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 1996;153:321-30 (Pubitemid 26074706)
    • (1996) American Journal of Psychiatry , vol.153 , Issue.3 , pp. 321-330
    • Green, M.F.1
  • 10
    • 0035930175 scopus 로고    scopus 로고
    • From the world health organization mental health: New understanding, new hope
    • Brundtland GH. From the world health organization mental health: new understanding, new hope. JAMA 2001;286:2391
    • (2001) JAMA , vol.286 , pp. 2391
    • Brundtland, G.H.1
  • 12
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association 4th edition. American Psychiatric Association; Washington DC
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Text Revision. 4th edition. American Psychiatric Association; Washington, DC: 2000
    • (2000) Diagnostic and Statistical Manual of Mental Disorders. Text Revision
  • 14
    • 40349102378 scopus 로고    scopus 로고
    • Should cognitive impairment be included in the diagnostic criteria for schizophrenia?
    • Keefe RS. Should cognitive impairment be included in the diagnostic criteria for schizophrenia? World Psychiatry 2008;7:22-8 (Pubitemid 351338182)
    • (2008) World Psychiatry , vol.7 , Issue.1 , pp. 22-28
    • Keefe, R.S.E.1
  • 15
    • 0034481144 scopus 로고    scopus 로고
    • Cognitive impairment in schizophrenia is the core of the disorder
    • Elvevag B, Goldberg TE. Cognitive impairment in schizophrenia is the core of the disorder. Crit Rev Neurobiol 2000;14:1-21 (Pubitemid 32193047)
    • (2000) Critical Reviews in Neurobiology , vol.14 , Issue.1 , pp. 1-21
    • Elvevag, B.1    Goldberg, T.E.2
  • 16
    • 0031903740 scopus 로고    scopus 로고
    • Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
    • DOI 10.1037/0894-4105.12.3.426
    • Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998;12:426-45 (Pubitemid 28323862)
    • (1998) Neuropsychology , vol.12 , Issue.3 , pp. 426-445
    • Heinrichs, R.W.1    Zakzanis, K.K.2
  • 17
    • 4344590645 scopus 로고    scopus 로고
    • Brief cognitive assessment in schizophrenia: Normative data for the Repeatable Battery for the Assessment of Neuropsychological Status
    • DOI 10.1016/j.schres.2003.10.009, PII S0920996403003517
    • Wilk CM, Gold JM, Humber K, et al. Brief cognitive assessment in schizophrenia: normative data for the repeatable battery for the assessment of neuropsychological status. Schizophr Res 2004;70:175-86 (Pubitemid 39141096)
    • (2004) Schizophrenia Research , vol.70 , Issue.2-3 , pp. 175-186
    • Wilk, C.M.1    Gold, J.M.2    Humber, K.3    Dickerson, F.4    Fenton, W.S.5    Buchanan, R.W.6
  • 18
    • 50249090405 scopus 로고    scopus 로고
    • 1-year follow-up study of cognitive function in first episode non-affective psychosis
    • Rodriguez-Sanchez JM, Perez-Iglesias R, Gonzalez-Blanch C, et al. 1-year follow-up study of cognitive function in first episode non-affective psychosis. Schizophr Res 2008;104:165-74
    • (2008) Schizophr Res , vol.104 , pp. 165-174
    • Rodriguez-Sanchez, J.M.1    Perez-Iglesias, R.2    Gonzalez-Blanch, C.3
  • 19
    • 0037327562 scopus 로고    scopus 로고
    • Context-processing deficits in schizophrenia: Diagnostic specificity, 4-week course, and relationships to clinical symptoms
    • DOI 10.1037/0021-843X.112.1.132
    • Barch DM, Carter CS, Cohen JD. Context processing deficit in schizophrenia: diagnostic specificity, 4-week course, and relationships to clinical symptoms. J Abnorm Psychol 2003;112:132-43 (Pubitemid 36249851)
    • (2003) Journal of Abnormal Psychology , vol.112 , Issue.1 , pp. 132-143
    • Barch, D.M.1    Braver, T.S.2    Carter, C.S.3    MacDonald III, A.W.4    Cohen, J.D.5
  • 22
    • 20844439028 scopus 로고    scopus 로고
    • A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia
    • Buchanan HW, Davis M, Goff D, et al. A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia. Schizophr Bull 2005;31:1-15
    • (2005) Schizophr Bull , vol.31 , pp. 1-15
    • Buchanan, H.W.1    Davis, M.2    Goff, D.3
  • 23
    • 79957561422 scopus 로고    scopus 로고
    • The FDA-NIMH-MATRICS guidelines fro clinical trila design og cognitive-enhancing drugs: What do we know 5 years later
    • Buchanan RW, Keefe RS, Umbricht D, et al. The FDA-NIMH-MATRICS guidelines fro clinical trila design og cognitive-enhancing drugs: what do we know 5 years later. Scizophr Bull 2010;37:1209-17
    • (2010) Scizophr Bull , vol.37 , pp. 1209-1217
    • Buchanan, R.W.1    Keefe, R.S.2    Umbricht, D.3
  • 24
    • 84855718455 scopus 로고    scopus 로고
    • Targacept presents statistically significant results for TC-5619 on measures of cognitive dysfunction in schizophrenia and negative symptoms of schizophrenia results from phase 2 study
    • presented at the April 7 [Last accessed 1 August 2011]
    • Targacept Presents Statistically Significant Results for TC-5619 on Measures of Cognitive Dysfunction in Schizophrenia and Negative Symptoms of Schizophrenia Results from Phase 2 study presented at the International Congress on Schizophrenia Research. April 7, 2011. Available from: www.targacept.com/wt/ page/pr-1302179429 [Last accessed 1 August 2011]
    • (2011) International Congress on Schizophrenia Research
  • 25
    • 68849104534 scopus 로고    scopus 로고
    • Validity of the CogState brief battery: Relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex
    • Maruff P, Thomas E, Cysique L, et al. Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex. Arch Clin Neuropsychol 2009;24:165-78
    • (2009) Arch Clin Neuropsychol , vol.24 , pp. 165-178
    • Maruff, P.1    Thomas, E.2    Cysique, L.3
  • 27
    • 0033001074 scopus 로고    scopus 로고
    • From research world to real world: Routine outcome measures are the key
    • DOI 10.1097/00001504-199903000-00008
    • Harrison G, Eaton WW. From research world to real world: routine outcome measures are the key. Curr Opin Psychiatry 1999;12:187-9 (Pubitemid 29131200)
    • (1999) Current Opinion in Psychiatry , vol.12 , Issue.2 , pp. 187-189
    • Harrison, G.1    Eaton, W.W.2
  • 28
    • 0035005247 scopus 로고    scopus 로고
    • Clinical trials in psychiatry: Do results apply to practice?
    • Seeman MV. Clinical trials in psychiatry: do results apply to practice? Can J Psychiatry 2001;46:352-5 (Pubitemid 32531568)
    • (2001) Canadian Journal of Psychiatry , vol.46 , Issue.4 , pp. 352-355
    • Seeman, M.V.1
  • 29
    • 0032528707 scopus 로고    scopus 로고
    • Getting research findings into practice. Closing the gap between research and practice: An overview of systematic reviews of interventions to promote the implementation of research findings
    • Bero LA, Grilli R, Grishaw JM, et al. Closing the gap between research and practice: an overview of systematic reviews of interventions to promote the implementation of research findings. BMJ 1998;317:465-8 (Pubitemid 28368041)
    • (1998) British Medical Journal , vol.317 , Issue.7156 , pp. 465-468
    • Bero, L.A.1    Grilli, R.2    Grimshaw, J.M.3    Harvey, E.4    Oxman, A.D.5    Thomson, M.A.6
  • 30
    • 53549118311 scopus 로고    scopus 로고
    • Systematic use of patient-rated depression severity monitoring: Is it helpful and feasible in clinical psychiatry?
    • Duffy FF, Chung H, Trivedi M, et al. Systematic use of patient-rated depression severity monitoring: is it helpful and feasible in clinical psychiatry? Psychiatr Serv 2008;59:1148-54
    • (2008) Psychiatr Serv , vol.59 , pp. 1148-1154
    • Duffy, F.F.1    Chung, H.2    Trivedi, M.3
  • 31
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • DOI 10.1176/appi.ajp.160.4.636
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003;160:636-45 (Pubitemid 41079594)
    • (2003) American Journal of Psychiatry , vol.160 , Issue.4 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 32
    • 33748052338 scopus 로고    scopus 로고
    • Subtyping schizophrenia: Implications for genetic research
    • DOI 10.1038/sj.mp.4001857, PII 4001857
    • Jablensky A. Subtyping schizophrenia: implications for genetic research. Mol Psychiatry 2006;11:815-36 (Pubitemid 44299104)
    • (2006) Molecular Psychiatry , vol.11 , Issue.9 , pp. 815-836
    • Jablensky, A.1
  • 33
    • 43149106929 scopus 로고    scopus 로고
    • Cognitive, clinical, and functional characteristics of verbally superior schizophrenia patients
    • DOI 10.1037/0894-4105.22.3.321, PII S0894410508600352
    • Heinrichs RW, Miles AA, Smith D, et al. Cognitive, clinical and functional characteristics of verbally superior schizophrenia patients. Neuropsychology 2008;22:321-8 (Pubitemid 351645172)
    • (2008) Neuropsychology , vol.22 , Issue.3 , pp. 321-328
    • Heinrichs, R.W.1    Miles, A.A.2    Smith, D.3    Zargarian, T.4    Vaz, S.M.5    Goldberg, J.O.6    Ammari, N.7
  • 34
    • 77955057243 scopus 로고    scopus 로고
    • An investigation of 3 neurocognitive subtypes in schizophrenia
    • Ammari N, Heinrichs RW, Miles AA. An investigation of 3 neurocognitive subtypes in schizophrenia. Schizophr Res 2010;121:32-8
    • (2010) Schizophr Res , vol.121 , pp. 32-8
    • Ammari, N.1    Heinrichs, R.W.2    Miles, A.A.3
  • 35
    • 66149166217 scopus 로고    scopus 로고
    • Is executive impairment associated with schizophrenic syndromes? A meta-analysis
    • Dibben CR, Rice C, Laws K, et al. Is executive impairment associated with schizophrenic syndromes? A meta-analysis. Psychol Med 2009;39:381-92
    • (2009) Psychol Med , vol.39 , pp. 381-392
    • Dibben, C.R.1    Rice, C.2    Laws, K.3
  • 36
    • 79955137651 scopus 로고    scopus 로고
    • Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia
    • Green MF, Schooler NR, Kern RS, et al. Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia. Am J Psychiatry 2001;168:400-7
    • (2001) Am J Psychiatry , vol.168 , pp. 400-407
    • Green, M.F.1    Schooler, N.R.2    Kern, R.S.3
  • 37
    • 0034661277 scopus 로고    scopus 로고
    • Age and neuropsychologic function in schizophrenia: A decline in executive abilities beyond that observed in healthy volunteers
    • DOI 10.1016/S0006-3223(00)00240-7, PII S0006322300002407
    • Fucetola R, Seidman LJ, Kremen WS, et al. Age and neuropsychologic function in schizophrenia: a decline in executive abilities beyond that observed in healthy volunteers. Biol Psychiatry 2000;48:137-46 (Pubitemid 30618803)
    • (2000) Biological Psychiatry , vol.48 , Issue.2 , pp. 137-146
    • Fucetola, R.1    Seidman, L.J.2    Kremen, W.S.3    Faraone, S.V.4    Goldstein, J.M.5    Tsuang, M.T.6
  • 38
    • 20444425251 scopus 로고    scopus 로고
    • Neurobiology of executive functions: Catecholamine influences on prefrontal cortical functions
    • DOI 10.1016/j.biopsych.2004.08.019, PII S0006322304009333
    • Arnsten AF, Li BM. Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. Biol Psychiatry 2005;57:1377-84 (Pubitemid 40798558)
    • (2005) Biological Psychiatry , vol.57 , Issue.11 , pp. 1377-1384
    • Arnsten, A.F.T.1    Li, B.-M.2
  • 39
    • 77953945440 scopus 로고    scopus 로고
    • Use of an acute challenge with d-amphetamine to model cognitive improvement in chronic schizophrenia
    • Pietrzak RH, Snyder PJ, Maruff P. Use of an acute challenge with d-amphetamine to model cognitive improvement in chronic schizophrenia. Hum Psychopharmacol Clin Exp 2010;25:353-8
    • (2010) Hum Psychopharmacol Clin Exp , vol.25 , pp. 353-358
    • Pietrzak, R.H.1    Snyder, P.J.2    Maruff, P.3
  • 40
    • 77949540094 scopus 로고    scopus 로고
    • Circumstances under which practice does not make perfect: A review of the practice effect literature in schizophrenia and its relevance to clinical treatment studies
    • Goldberg TE, Keefe RSE, Goldman RS, et al. Circumstances under which practice does not make perfect: a review of the practice effect literature in schizophrenia and its relevance to clinical treatment studies. Neuropsychopharmacology 2010;35:1053-62
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1053-1062
    • Goldberg, T.E.1    Rse, K.2    Goldman, R.S.3


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