Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor

Methods in Molecular Biology

Volumn 821, Issue , 2012, Pages 15-28

  Yu, Ker ^a   Toral Barza, Lourdes ^b  

^a FUDAN UNIVERSITY   (China)

^b Pfizer Oncology Research Unit   (United States)

Author keywords

DELFIA; mTOR; mTOR inhibitor; Rapamycin; WYE 125132

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBANILAMIDE DERIVATIVE; CRTC2 PROTEIN, HUMAN; FK 506 BINDING PROTEIN; MTORC1 COMPLEX, HUMAN; PROTEIN; PROTEIN KINASE INHIBITOR; PYRAZOLE DERIVATIVE; RAPAMYCIN; TRANSCRIPTION FACTOR; TUMOR MARKER; WYE 125132;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG DEVELOPMENT; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; DRUG DISCOVERY; HUMANS; PHENYLUREA COMPOUNDS; PROTEIN KINASE INHIBITORS; PROTEINS; PYRAZOLES; SIGNAL TRANSDUCTION; SIROLIMUS; TACROLIMUS BINDING PROTEIN 1A; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

MAMMALIA;

EID: 84555187728     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-430-8_2     Document Type: Article

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