Distribution of spontaneous gyrA mutations in 97 fluoroquinolone-resistant Helicobacter pylori isolates collected in France

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 1, 2012, Pages 550-551

  Garcia, Magali ^a   Raymond, Josette ^b   Garnier, Martine ^a   Cremniter, Julie ^a   Burucoa, Christophe ^a  

^a UNIVERSITÉ DE POITIERS   (France)

^b Institut Pasteur ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; FRANCE; GENE MUTATION; GYRA BACTERIAL GENE; GYRB BACTERIAL GENE; HELICOBACTER PYLORI; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; CIPROFLOXACIN; DNA GYRASE; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; FRANCE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION;

EID: 84455170067     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.05243-11     Document Type: Article

References (23)

1. Alm RA, et al. 1999. Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 397:176-180.
2. Bina JE, et al. 2000. Helicobacter pylori uptake and efflux: basis for intrinsic susceptibility to antibiotics in vitro. Antimicrob. Agents Chemother. 44:248-254. (Pubitemid 30060714)
3. Bogaerts P, Berhin C, Nizet H, Glupczynski Y. 2006. Prevalence and mechanisms of resistance to fluoroquinolones in Helicobacter pylori strains from patients living in Belgium. Helicobacter 11:441-445. (Pubitemid 44352615)
4. Burucoa C, Landron C, Garnier M, Fauchère JL. 2005. T2182C mutation is not associated with clarithromycin resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 49:868-870. (Pubitemid 40175723)
5. Cambau E, et al. 2009. Evaluation of a new test, genotype HelicoDR, for molecular detection of antibiotic resistance in Helicobacter pylori. J. Clin. Microbiol. 47:3600-3607.
6. Cattoir V, et al. 2007. Update on fluoroquinolone resistance in Helicobacter pylori: new mutations leading to resistance and first description of a gyrA polymorphism associated with hypersusceptibility. Int. J. Antimicrob. Agents 29:389-396. (Pubitemid 46357606)
7. Chang WL, et al. 2009. Resistance to metronidazole, clarithromycin and levofloxacin of Helicobacter pylori before and after clarithromycin-based therapy in Taiwan. J. Gastroenterol. Hepatol. 24:1230-1235.
8. Chey WD, Wong BC. 2007. Practice Parameters Committee of the American College of Gastroenterology American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am. J. Gastroenterol. 102:1808-1825. (Pubitemid 47206706)
9. Dunn BE, Cohen H, Blaser MJ. 1997. Helicobacter pylori. Clin. Microbiol. Rev. 10:720-741. (Pubitemid 27477732)
10. European Committee on Antimicrobial Susceptibility Testing. 2011. Clinical breakpoints for Helicobacter pylori. http:/www.eucast.org/fileadmin/ src/media/PDFs/EUCAST-files/Consultation/EUCAST-clinical-breakpoints-for- Helicobacter-pylori.pdf.
11. Fujimura S, Kato S, Iinuma K, Watanabe A. 2004. In vitro activity of fluoroquinolone and the gyrA gene mutation in Helicobacter pylori strains isolated from children. J. Med. Microbiol. 53:1019-1022. (Pubitemid 39391971)
12. Glocker E, Kist M. 2004. Rapid detection of point mutations in the gyrA gene of Helicobacter pylori conferring resistance to ciprofloxacin by a fluorescence resonance energy transfer-based real-time PCR approach. J. Clin. Microbiol. 42:2241-2246. (Pubitemid 38637854)
13. Grignon B, et al. 2002. Validation of diffusion methods for macrolide susceptibility testing of Helicobacter pylori. Microb. Drug Resist. 8:61-66. (Pubitemid 34298583)
14. Hofreuter D, Haas R. 2002. Characterization of two cryptic Helicobacter pylori plasmids: a putative source of horizontal gene transfer and gene shuffling. J. Bacteriol. 184:2755-2766. (Pubitemid 34457043)
15. Kusters JG, van Vliet AH, Kuipers EJ. 2006. Pathogenesis of Helicobacter pylori infection. Clin. Microbiol. Rev. 19:449-490. (Pubitemid 44134306)
16. Ling JM, Chan EW, Lam AW, Cheng AF. 2003. Mutations in topoisomerase genes of fluoroquinolone-resistant salmonellae in Hong Kong. Antimicrob. Agents Chemother. 47:3567-3573. (Pubitemid 37345721)
17. Malfertheiner P, et al. 2007. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 56:772-781. (Pubitemid 46854190)
18. Mégraud F. 2004. H pylori antibiotic resistance: prevalence, importance, and advances in testing. Gut 53:1374-1384. (Pubitemid 39120130)
19. Moore RA, Beckthold B, Wong S, Kureishi A, Bryan LE. 1995. Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori. Antimicrob. Agents Chemother. 39:107-111.
20. Raymond J, Lamarque D, Kalach N, Chaussade S, Burucoa C. 2010. High level of antimicrobial resistance in French Helicobacter pylori isolates. Helicobacter 15:21-27.
21. Rodríguez-Martínez JM. 2005. Mechanisms of plasmid-mediated resistance to quinolones. Enferm. Infecc. Microbiol. Clin. 23:25-31. (In Spanish.) (Pubitemid 40314661)
22. Tankovic J, Lascols C, Sculo Q, Petit JC, Soussy CJ. 2003. Single and double mutations in gyrA but not in gyrB are associated with low- and high-level fluoroquinolone resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 47:3942-3944. (Pubitemid 37485011)
23. Wang G, Wilson TJ, Jiang Q, Taylor DE. 2001. Spontaneous mutations that confer antibiotic resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 45:727-733. (Pubitemid 32182016)