Mutations in Topoisomerase Genes of Fluoroquinolone-Resistant Salmonellae in Hong Kong

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 11, 2003, Pages 3567-3573

  Ling, J M ^a   Chan, E W ^a   Lam, A W ^a   Cheng, A F ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; GENE MUTATION; GYRA GENE; GYRB GENE; HONG KONG; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARC GENE; PARE GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SALMONELLA ENTERICA;

ANTI-INFECTIVE AGENTS; DNA GYRASE; DNA TOPOISOMERASE IV; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FLUOROQUINOLONES; HONG KONG; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALMONELLA; SALMONELLA INFECTIONS;

EID: 0242385482     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.11.3567-3573.2003     Document Type: Article

References (52)

1. Breines, D. M., S. Ouabdesselam, E. Y. Ng, J. Tankovic, S. Shah, C. J. Soussy, and D. C. Hooper. 1997. Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV. Antimicrob. Agents Chemother. 41:175-179.
2. Brown, N. M., M. R. Millar, J. A. Frost, and B. Rowe. 1994. Ciprofloxacin resistance in Salmonella paratyphi A. J. Antimicrob. Chemother. 33:1258-1259.
3. Chu, Y.-W., E. T. S. Houang, and A. F. B. Cheng. 1998. Novel combination of mutations in the DNA gyrase and topoisomerase IV genes in laboratory-grown fluoroquinolone-resistant Shigella flexneri mutants. Antimicrob. Agents Chemother. 42:3051-3052.
4. Deguchi, T., A. Fukuoka, M. Yasuda, M. Nakano, S. Ozeki, E. Kanematsu, Y. Nishino, S. Ishibara, Y. Ban, and Y. Kawada. 1997. Alterations in the GyrA subunit of DNA gyrase and ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae. Antimicrob. Agents Chemother. 41:699-701.
5. Dutta, P., U. Mitra, S. Dutta, A. De, M. K. Chatterjee, and S. K. Bhattacharya. 2001. Ceftriaxone therapy in ciprofloxacin treatment failure in typhoid fever in children. Indian J. Med. Res. 113:210-213.
6. Everett, M. J., Y. F. Jin, V. Ricci, and L. J. V. Piddock. 1996. Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Antimicrob. Agents Chemother. 40:2380-2386.
7. Gensberg, K., Y. F. Jin, and L. J. V. Piddock. 1995. A novel gyrB mutation in a fluoroquinolone-resistant clinical isolate of Salmonella typhimurium. FEMS Microbiol. Lett. 132:57-60.
8. Gibb, A. P., C. S. Lewin, and O. J. Garden. 1991. Development of quinolone resistance in and multiple antibiotic resistance in Salmonella bovismorbificans in a pancreatic abscess. J. Antimicrob. Chemother. 28:318-321.
9. Giraud, E., A. Brisabois, J. L. Martel, and E. Chaslus-Dancla. 1999. Comparative studies of mutations in animal isolates and experimental in vitro-and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field. Antimicrob. Agents Chemother. 43:2131-2137.
10. Giraud, E., A. Cloeckaert, D. Kerboeuf, and E. Chaslus-Dancla. 2000. Evidence for active efflux as the primary mechanism of resistance to ciprofloxacin in Salmonella enterica serovar Typhimurium. Antimicrob. Agents Chemother. 44:1223-1228.
11. González, I., M. Georgiou, F. Alcaide, D. Balas, J. Linares, and A. G. de la Campa. 1998. Fluoroquinolone resistance mutations in the parC, parE, and gyrA genes of clinical isolates of viridans group streptococci. Antimicrob. Agents Chemother. 42:2792-2798.
12. Griggs, D. J., K. Gensberg, and L. J. V. Piddock. 1996. Mutations in gyrA of quinolone-resistant salmonella serotypes isolated from humans and animals. Antimicrob. Agents Chemother. 40:1009-1013.
13. Heisig, P. 1993. High-level fluoroquinolone resistance in a Salmonella typhimurium isolate due to alterations in both gyrA and gyrB genes. J. Antimicrob. Chemother. 32:367-378.
14. Heisig, P. 1996. Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli. Antimicrob. Agents Chemother. 40:879-885.
15. Helms, M., P. Vastrup, P. Gerner-Smidt, and K. Malbak. 2002. Excess mortality associated with antimicrobial drug-resistant Salmonella typhimurium. Emerg. Infect. Dis. 8:490-495.
16. Heurtin-Le Corre, C., P.-Y. Donnio, M. Perrin, M.-F. Travert, and J.-L. Avril. 1999. Increasing incidence and comparison of nalidixic acid-resistant Salmonella enterica subsp. emerica serotype Typhimurium isolates from humans and animals. J. Clin. Microbiol. 37:266-269.
17. Hiasa, H. 2002. The Glu-84 of the ParC subunit plays critical roles in both topoisomerase IV-quinolone and topoisomerase IV-DNA interactions. Biochemistry 41:11779-11785.
18. Hirose, K., A. Hashimoto, K. Tamura, Y. Kawamura, T. Ezaki, H. Sagara, and H. Watanabe. 2002. DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A. Antimicrob. Agents Chemother. 46:3249-3252.
19. Houssaye, S., L. Gutmann, and E. Varon. 2002. Topoisomerase mutations associated with in vitro selection of resistance to moxifloxacin in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 46:2712-2715.
20. Howard, A. J., T. D. Joseph, L. L. Bloodworth, J. A. Frost, H. Chart, and B. Rowe. 1990. The emergence of ciprofloxacin resistance in Salmonella typhimunum. J. Antimicrob. Chemother. 26:296-298.
21. Kato, J.-I., H. Suzuki, and H. Ikeda. 1992. Purification and characterization of DNA topoisomerase IV in Escherichia coli. J. Biol. Chem. 267:25676-25684.
22. Kern, W. V., M. Oethinger, A. S. Jellen-Ritter, and S. B. Levy. 2000. Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli. Antimicrob. Agents Chemother. 44:814-820.
23. Kim, J. H., E. H. Cho, K. S. Kim, H. Y. Kim, and Y. M. Kim. 1998. Cloning and nucleotide sequence of the DNA gyrase gyrA gene from Serratia marcescens and characterization of mutations in gyrA of quinolone-resistant clinical isolates. Antimicrob. Agents Chemother. 42:190-193.
24. Kumagai, Y., J.-I. Kato, K. Hoshino, T. Akasaka, K. Sato, and H. Ikeda. 1996. Quinolone-resistant mutants of Escherichia coli DNA topoisomerase IV parC gene. Antimicrob. Agents Chemother. 40:710-714.
25. Linde, H.-J., F. Notka, M. Metz, B. Kochanowski, P. Heisig, and N. Lehn. 2000. In vivo increase in resistance to ciprofloxacin in Escherichia coli associated with deletion of the C-terminal part of MarR. Antimicrob. Agents Chemother. 44:1865-1868.
26. Ling, J. M., N. W. S. Lo, Y. M. Ho, K. M. Kam, C. H. Ma, S. C. Wong, and A. F. Cheng. 1996. Emerging resistance in Salmonella enterica serotype Typhi in Hong Kong. Int. J. Antimicrob. Agents 7:161-166.
27. Ling, J. M., I. C. Koo, K. M. Kam, and A. F. Cheng. 1998. Antimicrobial susceptibilities and molecular epidemiology of Salmonella enterica serotype Enteritidis in Hong Kong from 1986 to 1996. J. Clin. Microbiol. 36:1693-1699.
28. Ling, J. M., I. C. Koo, and A. F. Cheng. 2001. Epidemiological analysis of Salmonella enterica serotype Typhimurium from Hong Kong by ribotyping and PFGE. Scand. J. Infect. Dis. 33:272-278.
29. Ling, J. M., E. W. C. Chan, and A. F. Cheng. 2001. Molecular epidemiologic analysis of Salmonella enterica serotype Derby infections in Hong Kong. J. Infect. 42:145-153.
30. Malbak, K., P. Gerner-Smidt, and H. C. Wegener. 2002. Increasing quinolone resistance in Salmonella enterica serotype Enteritidis. Emerg. Infect. Dis. 8:514-515.
31. McIlhatton, B. P., C. Keating, M. D. Curran, M. F. McMullin, J. G. Barr, J. A. Madrigal, and D. Middleton. 2002. Identification of medically important pathogenic fungi by reference strand-mediated conformational analysis (RSCA). J. Med. Microbiol. 51:468-478.
32. National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A4. National Committee for Clinical Laboratory Standards, Wayne, Pa.
33. Ouabdesselam, S., D. C. Hooper, J. Tankovic, and C. J. Soussy. 1995. Detection of gyrA and gyrB mutations in quinolone-resistant clinical isolates of Escherichia coli by single-strand conformational polymorphism analysis and determination of levels of resistance conferred by two different single gyrA mutations. Antimicrob. Agents Chemother. 39:1667-1670.
34. Ouabdesselam, S., J. Tankovic, and C. J. Soussy. 1996. Quinolone resistance mutations in the gyrA gene of clinical isolates of Salmonella. Microb. Drug Resist. 2:299-302.
35. Peng, H., and K. J. Marians. 1993. Escherichia coli topoisomerase IV. J. Biol. Chem. 268:24481-24490.
36. Piddock, L. J. 2002. Fluoroquinolone resistance in Salmonella serovars isolated from humans and food animals. FEMS Microbiol. Rev. 26:3-16.
37. Piddock, L. J. V., K. Whale, and R. Wise. 1990. Quinolone resistance in salmonella: clinical experience. Lancet 335:1459.
38. Piddock, L. J. V., V. Ricci, I. McLaren, and D. J. Griggs. 1998. Role of mutation in the gyrA and parC genes of nalidixic acid-resistant salmonella serotypes isolated from animals in the United Kingdom. J. Antimicrob. Chemother. 41:635-641.
39. Reyna, F., M. Huesca, V. Gonalez, and L. Y. Fuchs. 1995. Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance. Antimicrob. Agents Chemother. 39:1621-1623.
40. Springer, A. L., and M. B. Schmig. 1993. Molecular characterization of the Salmonella typhimurium parE gene. Nucleic Acids Res. 21:1805-1809.
41. Tankovic, J., R. Bachoual, S. Ouabdesselam, A. Boudjadja, and C. J. Soussy. 1999. In vitro activity of moxifloxacin against fluoroquinolone-resistant strains of aerobic gram-negative bacilli and Enterococcus fecalis. J. Antimicrob. Chemother. 43:19-23.
42. Threlfall, E. J., L. R. Ward, and B. Rowe. 1999. Resistance to ciprofloxacin in non-typhoidal salmonellas from humans in England and Wales - the current situation. Clin. Microbiol. Infect. 5:130-134.
43. Troung, Q. C., J.-C. N. Van, D. Shlaes, L. Gutmann, and N. J. Moreau. 1997. A novel, double mutation in DNA gyrase A of Escherichia coli conferring resistance to quinolone antibiotics. Antimicrob. Agents Chemother. 41:85-90.
44. Vasallo, F. J., P. Martin-Rabadan, L. Alcala, J. M. Garcia-Lechuz, M. Rodriguez-Creixems, and E. Bouza. 1998. Failure of ciprofloxacin therapy for invasive nontyphoidal salmonellosis. Clin. Infect. Dis. 26:535-536.
45. Vila, J., J. Ruiz, P. Goni, and M. T. J. de Anta. 1996. Detection of mutations in parC in quinolone-resistant clinical isolates of Escherichia coli. Antimicrob. Agents Chemother. 40:491-493.
46. Wain, J., N. T. Hoa, N. T. Chin, H. Vinh, M. J. Everett, T. S. Diep, N. P. J. Day, T. Solomon, N. J. White, L. J. V. Piddock, and C. M. Parry. 1997. Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment. Clin. Infect. Dis. 25:1404-1410.
47. Walker, R. A., A. J. Lawson, E. A. Lindsay, L. R. Ward, P. A. Wright, P. A. Bolton, F. J. Wareing, D. R. Corkish, R. H. Davies, and E. J. Threlfall. 2000. Decreased susceptibility to ciprofloxacin in outbreak associated multiresistant Salmonella typhimurium DT104. Vet. Rec. 147:395-396.
48. Walker, R. A., N. Saunders, A. J. Lawson, E. A. Lindsay, M. Dassama, L. R. Ward, M. J. Woodward, R. H. Davies, E. Liebana, and E. J. Threlfall. 2001. Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates. J. Clin. Microbiol. 39:1443-1448.
49. Weigel, L. M., C. D. Steward, and F. C. Tenover. 1998. gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae. Antimicrob. Agents Chemother. 42:2661-2667.
50. Weigel, L. M., G. J. Anderson, R. R. Facklam, and F. C. Tenover. 2001. Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 45:3517-3523.
51. Wiuff, C., M. Madsen, D. L. Baggesen, and F. M. Aarestrup. 2000. Quinolone resistance among Salmonella enterica from cattle broilers, and swine in Denmark. Microb. Drug Resist. 6:11-17.
52. Zhou, J., Y. Dong, X. Zhao, S. Lee, A. Amin, S. Ramaswamy, J. Domagala, J. M. Musser, and K. Drlica. 2000. Selection of antibiotic-resistant bacterial mutants: allelic diversity among fluoroquinolone-resistant mutations. J. Infect. Dis. 182:517-525.