메뉴 건너뛰기




Volumn 77, Issue 6, 2009, Pages 1002-1010

A newly synthetic chromium complex-Chromium (d-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport

Author keywords

AMP activated protein kinase; Chromium; Glucose transport; Insulin resistance

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CHROMIUM (DEXTRO PHENYLALANINE) 3; CHROMIUM DERIVATIVE; DEOXYGLUCOSE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; UNCLASSIFIED DRUG;

EID: 60649110428     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.11.018     Document Type: Article
Times cited : (32)

References (54)
  • 2
    • 0032854777 scopus 로고    scopus 로고
    • Overproduction of insulin in the chromium-deficient rat
    • Striffler J.S., Polansky M.M., and Anderson R.A. Overproduction of insulin in the chromium-deficient rat. Metabolism 48 (1999) 1063-1068
    • (1999) Metabolism , vol.48 , pp. 1063-1068
    • Striffler, J.S.1    Polansky, M.M.2    Anderson, R.A.3
  • 3
    • 0033786814 scopus 로고    scopus 로고
    • Chromium supplementation improves insulin resistance in patients with Type 2 diabetes mellitus
    • Morris B.W., Kouta S., Robinson R., MacNeil S., and Heller S. Chromium supplementation improves insulin resistance in patients with Type 2 diabetes mellitus. Diabet Med 17 (2000) 684-685
    • (2000) Diabet Med , vol.17 , pp. 684-685
    • Morris, B.W.1    Kouta, S.2    Robinson, R.3    MacNeil, S.4    Heller, S.5
  • 4
    • 41649107893 scopus 로고    scopus 로고
    • Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance
    • Horvath E.M., Tackett L., McCarthy A.M., Raman P., Brozinick J.T., and Elmendorf J.S. Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance. Mol Endocrinol 22 (2008) 937-950
    • (2008) Mol Endocrinol , vol.22 , pp. 937-950
    • Horvath, E.M.1    Tackett, L.2    McCarthy, A.M.3    Raman, P.4    Brozinick, J.T.5    Elmendorf, J.S.6
  • 7
    • 44449126331 scopus 로고    scopus 로고
    • Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice
    • Sreejayan N., Dong F., Kandadi M.R., Yang X., and Ren J. Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice. Obesity (Silver Spring) 16 (2008) 1331-1337
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1331-1337
    • Sreejayan, N.1    Dong, F.2    Kandadi, M.R.3    Yang, X.4    Ren, J.5
  • 8
    • 0038199737 scopus 로고    scopus 로고
    • Management of cellular energy by the AMP-activated protein kinase system
    • Hardie D.G., Scott J.W., Pan D.A., and Hudson E.R. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett 546 (2003) 113-120
    • (2003) FEBS Lett , vol.546 , pp. 113-120
    • Hardie, D.G.1    Scott, J.W.2    Pan, D.A.3    Hudson, E.R.4
  • 10
    • 0037428456 scopus 로고    scopus 로고
    • Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells
    • Hallows K.R., McCane J.E., Kemp B.E., Witters L.A., and Foskett J.K. Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells. J Biol Chem 278 (2003) 998-1004
    • (2003) J Biol Chem , vol.278 , pp. 998-1004
    • Hallows, K.R.1    McCane, J.E.2    Kemp, B.E.3    Witters, L.A.4    Foskett, J.K.5
  • 11
    • 0033815967 scopus 로고    scopus 로고
    • Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
    • Woods A., Azzout-Marniche D., Foretz M., Stein S.C., Lemarchand P., Ferre P., et al. Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol 20 (2000) 6704-6711
    • (2000) Mol Cell Biol , vol.20 , pp. 6704-6711
    • Woods, A.1    Azzout-Marniche, D.2    Foretz, M.3    Stein, S.C.4    Lemarchand, P.5    Ferre, P.6
  • 12
    • 0029093341 scopus 로고
    • High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5′-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase
    • Kudo N., Barr A.J., Barr R.L., Desai S., and Lopaschuk G.D. High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5′-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase. J Biol Chem 270 (1995) 17513-17520
    • (1995) J Biol Chem , vol.270 , pp. 17513-17520
    • Kudo, N.1    Barr, A.J.2    Barr, R.L.3    Desai, S.4    Lopaschuk, G.D.5
  • 13
    • 0030015194 scopus 로고    scopus 로고
    • Characterization of 5′AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia
    • Kudo N., Gillespie J.G., Kung L., Witters L.A., Schulz R., Clanachan A.S., et al. Characterization of 5′AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia. Biochim Biophys Acta 1301 (1996) 67-75
    • (1996) Biochim Biophys Acta , vol.1301 , pp. 67-75
    • Kudo, N.1    Gillespie, J.G.2    Kung, L.3    Witters, L.A.4    Schulz, R.5    Clanachan, A.S.6
  • 14
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • Winder W.W., and Hardie D.G. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol 270 (1996) EE299-EE304
    • (1996) Am J Physiol , vol.270
    • Winder, W.W.1    Hardie, D.G.2
  • 15
    • 0141905919 scopus 로고    scopus 로고
    • Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
    • Rutter G.A., Da Silva Xavier G., and Leclerc I. Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis. Biochem J 375 (2003) 1-16
    • (2003) Biochem J , vol.375 , pp. 1-16
    • Rutter, G.A.1    Da Silva Xavier, G.2    Leclerc, I.3
  • 16
    • 0034687210 scopus 로고    scopus 로고
    • Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
    • Marsin A.S., Bertrand L., Rider M.H., Deprez J., Beauloye C., Vincent M.F., et al. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr Biol 10 (2000) 1247-1255
    • (2000) Curr Biol , vol.10 , pp. 1247-1255
    • Marsin, A.S.1    Bertrand, L.2    Rider, M.H.3    Deprez, J.4    Beauloye, C.5    Vincent, M.F.6
  • 19
    • 0041355355 scopus 로고    scopus 로고
    • Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells
    • Morrow V.A., Foufelle F., Connell J.M., Petrie J.R., Gould G.W., and Salt I.P. Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. J Biol Chem 278 (2003) 31629-31639
    • (2003) J Biol Chem , vol.278 , pp. 31629-31639
    • Morrow, V.A.1    Foufelle, F.2    Connell, J.M.3    Petrie, J.R.4    Gould, G.W.5    Salt, I.P.6
  • 20
    • 0033026928 scopus 로고    scopus 로고
    • The cerebral metabolic consequences of nitric oxide synthase deficiency: glucose utilization in endothelial and neuronal nitric oxide synthase null mice
    • Browne S.E., Ayata C., Huang P.L., Moskowitz M.A., and Beal M.F. The cerebral metabolic consequences of nitric oxide synthase deficiency: glucose utilization in endothelial and neuronal nitric oxide synthase null mice. J Cereb Blood Flow Metab 19 (1999) 144-148
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 144-148
    • Browne, S.E.1    Ayata, C.2    Huang, P.L.3    Moskowitz, M.A.4    Beal, M.F.5
  • 21
    • 0035902547 scopus 로고    scopus 로고
    • Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase
    • Duplain H., Burcelin R., Sartori C., Cook S., Egli M., Lepori M., et al. Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation 104 (2001) 342-345
    • (2001) Circulation , vol.104 , pp. 342-345
    • Duplain, H.1    Burcelin, R.2    Sartori, C.3    Cook, S.4    Egli, M.5    Lepori, M.6
  • 22
    • 0038665339 scopus 로고    scopus 로고
    • The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance
    • Vicent D., Ilany J., Kondo T., Naruse K., Fisher S.J., Kisanuki Y.Y., et al. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest 111 (2003) 1373-1380
    • (2003) J Clin Invest , vol.111 , pp. 1373-1380
    • Vicent, D.1    Ilany, J.2    Kondo, T.3    Naruse, K.4    Fisher, S.J.5    Kisanuki, Y.Y.6
  • 23
    • 34548486662 scopus 로고    scopus 로고
    • Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2
    • Turdi S., Li Q., Lopez F.L., and Ren J. Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2. Life Sci 81 (2007) 895-905
    • (2007) Life Sci , vol.81 , pp. 895-905
    • Turdi, S.1    Li, Q.2    Lopez, F.L.3    Ren, J.4
  • 24
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
    • Smiley S.T., Reers M., Mottola-Hartshorn C., Lin M., Chen A., Smith T.W., et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci USA 88 (1991) 3671-3675
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3671-3675
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3    Lin, M.4    Chen, A.5    Smith, T.W.6
  • 25
    • 20044372016 scopus 로고    scopus 로고
    • Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells
    • Konrad D., Rudich A., Bilan P.J., Patel N., Richardson C., Witters L.A., et al. Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells. Diabetologia 48 (2005) 954-966
    • (2005) Diabetologia , vol.48 , pp. 954-966
    • Konrad, D.1    Rudich, A.2    Bilan, P.J.3    Patel, N.4    Richardson, C.5    Witters, L.A.6
  • 27
    • 27644477357 scopus 로고    scopus 로고
    • AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart
    • Li J., Miller E.J., Ninomiya-Tsuji J., Russell III R.R., and Young L.H. AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circ Res 97 (2005) 872-879
    • (2005) Circ Res , vol.97 , pp. 872-879
    • Li, J.1    Miller, E.J.2    Ninomiya-Tsuji, J.3    Russell III, R.R.4    Young, L.H.5
  • 28
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • Zong H., Ren J.M., Young L.H., Pypaert M., Mu J., Birnbaum M.J., et al. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci USA 99 (2002) 15983-15987
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3    Pypaert, M.4    Mu, J.5    Birnbaum, M.J.6
  • 30
    • 39549092137 scopus 로고    scopus 로고
    • AMP-activated protein kinase conducts the ischemic stress response orchestra
    • Young L.H. AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation 117 (2008) 832-840
    • (2008) Circulation , vol.117 , pp. 832-840
    • Young, L.H.1
  • 31
    • 78149279712 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
    • Russell III R.R., Li J., Coven D.L., Pypaert M., Zechner C., Palmeri M., et al. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 114 (2004) 495-503
    • (2004) J Clin Invest , vol.114 , pp. 495-503
    • Russell III, R.R.1    Li, J.2    Coven, D.L.3    Pypaert, M.4    Zechner, C.5    Palmeri, M.6
  • 32
    • 0022544189 scopus 로고
    • High performance liquid chromatography: a rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue
    • Sellevold O.F., Jynge P., and Aarstad K. High performance liquid chromatography: a rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue. J Mol Cell Cardiol 18 (1986) 517-527
    • (1986) J Mol Cell Cardiol , vol.18 , pp. 517-527
    • Sellevold, O.F.1    Jynge, P.2    Aarstad, K.3
  • 33
    • 22544469153 scopus 로고    scopus 로고
    • AMP-activated protein kinase: a key stress signaling pathway in the heart
    • Young L.H., Li J., Baron S.J., and Russell R.R. AMP-activated protein kinase: a key stress signaling pathway in the heart. Trends Cardiovasc Med 15 (2005) 110-118
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 110-118
    • Young, L.H.1    Li, J.2    Baron, S.J.3    Russell, R.R.4
  • 34
    • 33645381037 scopus 로고    scopus 로고
    • Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism
    • Chen G., Liu P., Pattar G.R., Tackett L., Bhonagiri P., Strawbridge A.B., et al. Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism. Mol Endocrinol 20 (2006) 857-870
    • (2006) Mol Endocrinol , vol.20 , pp. 857-870
    • Chen, G.1    Liu, P.2    Pattar, G.R.3    Tackett, L.4    Bhonagiri, P.5    Strawbridge, A.B.6
  • 35
    • 33749234572 scopus 로고    scopus 로고
    • Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions
    • Pattar G.R., Tackett L., Liu P., and Elmendorf J.S. Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions. Mutat Res 610 (2006) 93-100
    • (2006) Mutat Res , vol.610 , pp. 93-100
    • Pattar, G.R.1    Tackett, L.2    Liu, P.3    Elmendorf, J.S.4
  • 36
    • 0018410411 scopus 로고
    • Chromium deficiency during total parenteral nutrition
    • Freund H., Atamian S., and Fischer J.E. Chromium deficiency during total parenteral nutrition. JAMA 241 (1979) 496-498
    • (1979) JAMA , vol.241 , pp. 496-498
    • Freund, H.1    Atamian, S.2    Fischer, J.E.3
  • 37
    • 0022496578 scopus 로고
    • Chromium deficiency after long-term total parenteral nutrition
    • Brown R.O., Forloines-Lynn S., Cross R.E., and Heizer W.D. Chromium deficiency after long-term total parenteral nutrition. Dig Dis Sci 31 (1986) 661-664
    • (1986) Dig Dis Sci , vol.31 , pp. 661-664
    • Brown, R.O.1    Forloines-Lynn, S.2    Cross, R.E.3    Heizer, W.D.4
  • 38
    • 0029998809 scopus 로고    scopus 로고
    • Neurologic symptoms due to possible chromium deficiency in long-term parenteral nutrition that closely mimic metronidazole-induced syndromes
    • Verhage A.H., Cheong W.K., and Jeejeebhoy K.N. Neurologic symptoms due to possible chromium deficiency in long-term parenteral nutrition that closely mimic metronidazole-induced syndromes. JPEN J Parenter Enteral Nutr 20 (1996) 123-127
    • (1996) JPEN J Parenter Enteral Nutr , vol.20 , pp. 123-127
    • Verhage, A.H.1    Cheong, W.K.2    Jeejeebhoy, K.N.3
  • 40
    • 0031695322 scopus 로고    scopus 로고
    • Effects of chromium on body composition and weight loss
    • Anderson R.A. Effects of chromium on body composition and weight loss. Nutr Rev 56 (1998) 266-270
    • (1998) Nutr Rev , vol.56 , pp. 266-270
    • Anderson, R.A.1
  • 41
    • 0031730119 scopus 로고    scopus 로고
    • Chromium, glucose intolerance and diabetes
    • Anderson R.A. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 17 (1998) 548-555
    • (1998) J Am Coll Nutr , vol.17 , pp. 548-555
    • Anderson, R.A.1
  • 42
    • 0034016828 scopus 로고    scopus 로고
    • Diabetes mellitus: subclinical cardiovascular disease and risk of incident cardiovascular disease and all-cause mortality
    • Kuller L.H., Velentgas P., Barzilay J., Beauchamp N.J., O'Leary D.H., and Savage P.J. Diabetes mellitus: subclinical cardiovascular disease and risk of incident cardiovascular disease and all-cause mortality. Arterioscler Thromb Vasc Biol 20 (2000) 823-829
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 823-829
    • Kuller, L.H.1    Velentgas, P.2    Barzilay, J.3    Beauchamp, N.J.4    O'Leary, D.H.5    Savage, P.J.6
  • 43
    • 0033646935 scopus 로고    scopus 로고
    • Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level
    • Temelkova-Kurktschiev T.S., Koehler C., Henkel E., Leonhardt W., Fuecker K., and Hanefeld M. Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level. Diabetes Care 23 (2000) 1830-1834
    • (2000) Diabetes Care , vol.23 , pp. 1830-1834
    • Temelkova-Kurktschiev, T.S.1    Koehler, C.2    Henkel, E.3    Leonhardt, W.4    Fuecker, K.5    Hanefeld, M.6
  • 44
    • 33846016991 scopus 로고    scopus 로고
    • Impact of abnormal glucose tolerance, hypertension and other risk factors on coronary artery disease
    • Nakamura Y., Saitoh S., Takagi S., Ohnishi H., Chiba Y., Kato N., et al. Impact of abnormal glucose tolerance, hypertension and other risk factors on coronary artery disease. Circ J 71 (2007) 20-25
    • (2007) Circ J , vol.71 , pp. 20-25
    • Nakamura, Y.1    Saitoh, S.2    Takagi, S.3    Ohnishi, H.4    Chiba, Y.5    Kato, N.6
  • 45
    • 38749137749 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
    • Miller E.J., Li J., Leng L., McDonald C., Atsumi T., Bucala R., et al. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 451 (2008) 578-582
    • (2008) Nature , vol.451 , pp. 578-582
    • Miller, E.J.1    Li, J.2    Leng, L.3    McDonald, C.4    Atsumi, T.5    Bucala, R.6
  • 48
    • 23044432463 scopus 로고    scopus 로고
    • Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
    • Hawley S.A., Pan D.A., Mustard K.J., Ross L., Bain J., Edelman A.M., et al. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2 (2005) 9-19
    • (2005) Cell Metab , vol.2 , pp. 9-19
    • Hawley, S.A.1    Pan, D.A.2    Mustard, K.J.3    Ross, L.4    Bain, J.5    Edelman, A.M.6
  • 49
    • 23044437445 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
    • Woods A., Dickerson K., Heath R., Hong S.P., Momcilovic M., Johnstone S.R., et al. Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2 (2005) 21-33
    • (2005) Cell Metab , vol.2 , pp. 21-33
    • Woods, A.1    Dickerson, K.2    Heath, R.3    Hong, S.P.4    Momcilovic, M.5    Johnstone, S.R.6
  • 50
    • 50249121976 scopus 로고    scopus 로고
    • Antioxidant enzyme activities as affected by trivalent and hexavalent chromium species in Fontinalis antipyretica Hedw
    • Dazy M., Beraud E., Cotelle S., Meux E., Masfaraud J.F., and Ferard J.F. Antioxidant enzyme activities as affected by trivalent and hexavalent chromium species in Fontinalis antipyretica Hedw. Chemosphere 73 (2008) 281-290
    • (2008) Chemosphere , vol.73 , pp. 281-290
    • Dazy, M.1    Beraud, E.2    Cotelle, S.3    Meux, E.4    Masfaraud, J.F.5    Ferard, J.F.6
  • 51
    • 55649118870 scopus 로고    scopus 로고
    • Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts
    • Slodzinski M.K., Aon M.A., and O'Rourke B. Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts. J Mol Cell Cardiol (2008)
    • (2008) J Mol Cell Cardiol
    • Slodzinski, M.K.1    Aon, M.A.2    O'Rourke, B.3
  • 52
    • 33744514139 scopus 로고    scopus 로고
    • Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
    • Cool B., Zinker B., Chiou W., Kifle L., Cao N., Perham M., et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab 3 (2006) 403-416
    • (2006) Cell Metab , vol.3 , pp. 403-416
    • Cool, B.1    Zinker, B.2    Chiou, W.3    Kifle, L.4    Cao, N.5    Perham, M.6
  • 54
    • 0034803430 scopus 로고    scopus 로고
    • AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation
    • Culmsee C., Monnig J., Kemp B.E., and Mattson M.P. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J Mol Neurosci 17 (2001) 45-58
    • (2001) J Mol Neurosci , vol.17 , pp. 45-58
    • Culmsee, C.1    Monnig, J.2    Kemp, B.E.3    Mattson, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.