Involvement of FcγR I (CD64) in the mechanism of HIV-1 inhibition by polyclonal IgG purified from infected patients in cultured monocyte-derived macrophages

Journal of Immunology

Volumn 173, Issue 10, 2004, Pages 6274-6283

  Holl, Vincent ^a   Hemmerter, Stéphane ^a   Burrer, Renaud ^a   Schmidt, Sylvie ^a   Bohbot, Alain ^b   Aubertin, Anne Marie ^a   Moog, Christiane ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Department of Neurology CHU Centre Hospitalier Universitaire   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FC GAMMA RECEPTOR ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MONOCYTE; MONOCYTE DERIVED MACROPHAGE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; VACCINATION; VIRUS INHIBITION; VIRUS NEUTRALIZATION; VIRUS REPLICATION;

EID: 8444246266     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.10.6274     Document Type: Article

References (48)

1. Ho, D. D. 1998. Toward HIV eradication or remission: the tasks ahead. Science 2801866.
2. Aquaro, S., P. Bagnarelli, T. Guenci, A. De Luca, M. Clementi, E. Balestra, R. Calio, and C. F. Perno. 2002. Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus. J. Med. Virol. 68:479.
3. Aquaro, S., R. Calio, J. Balzarini, M. C. Bellocchi, E. Garaci, and C. F. Perno. 2002. Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir. Antiviral Res. 55:209.
4. Sonza, S., H. P. Mutimer, R. Oelrichs, D. Jardine, K. Harvey, A. Dunne, D. F. Purcell, C. Birch, and S. M. Crowe. 2001. Monocytes harbor replication-competent, non latent HIV-1 in patients on HAART. AIDS 15:17.
5. + monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy. J. Virol. 76:707.
6. Perno, C. F., S. M. Crowe, and R. S. Kornbluth. 1997. A continuing enigma: the role of cells of macrophage lineage in the development of HIV disease. J. Leukocyte Biol. 62:1.
7. Embretson, J., M. Zupancic, J. L. Ribas, A. Burke, P. Racz, K. Tenner-Racz, and A. T. Haase. 1993. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362:359.
8. Orenstein, J. M., C. Fox, and S. M. Wahl. 1997. Macrophages as a source of HIV during opportunistic infections. Science 276:1857.
9. Gendelman, H. E., J. M. Orenstein, L. M. Baca, B. Weiser, H. Burger, D. C. Kalter, and M. S. Meltzer. 1989. The macrophage in the persistence and pathogenesis of HIV infection. AIDS 3:475.
10. Herbein, G., A. Coaquette, D. Perez-Bercoff, and G. Pancino. 2002. Macrophage activation and HIV infection: can the Trojan horse turn into a fortress? Curr. Mol. Med. 2:723.
11. Meltzer, M. S., and H. E. Gendelman. 1992. Mononuclear phagocytes as targets, tissue reservoirs, and immunoregulatory cells in human immunodeficiency virus disease. Curr. Top. Microbiol. Immunol. 181:239.
12. + T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): implications for HIV-1 infections of humans. Proc. Natl. Acad. Sci. USA 98:658.
13. Martin, J. C., and J. C. Bandres. 1999. Cells of the monocyte-macrophage lineage and pathogenesis of HIV-1 infection. J. Acquir. Immune Defic. Syndr. 22:413.
14. Kaul, M., G. A. Garden, and S. A. Lipton. 2001. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410:988.
15. Zhuge, W., F. Jia, I. Adany, O. Narayan, and E. B. Stephens. 1997. Plasmas from lymphocyte- and macrophage-tropic SIVmac-infected macaques have antibodies with a broader spectrum of virus neutralization activity in macrophage versus lymphocyte cultures. Virology 227:24.
16. Ruppach, H., P. Nara, I. Raudonat, Z. Elanjikal, H. Rubsamen-Waigmann, and U. Dietrich. 2000. Human immunodeficiency virus (HIV)-positive sera obtained shortly after seroconversion neutralize autologous HIV type 1 isolates on primary macrophages but not on lymphocytes. J. Virol. 74:5403.
17. Moog, C., C. Spenlehauer, H. Fleury, F. Heshmati, S. Saragosti, F. Letourneur, A. Kirn, and A. M. Aubertin. 1997. Neutralization of primary human immunodeficiency virus type 1 isolates: a study of parameters implicated in neutralization in vitro. AIDS Res. Hum. Retroviruses 13:19.
18. Mascola, J. R., M. K. Louder, C. Winter, R. Prabhakara, S. C. De Rosa, D. C. Douek, B. J. Hill, D. Gabuzda, and M. Roederer. 2002. Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells. J. Virol. 76:4810.
19. Faradji, A., A. Bohbot, M. Schmitt-Goguel, J. C. Siffert, S. Dumont, M. L. Wiesel, Y. Piemont, A. Eischen, J. P. Bergerat, J. Bartholeyns, et al. 1994. Large scale isolation of human blood monocytes by continuous flow centrifugation leukapheresis and counterflow centrifugation elutriation for adoptive cellular immunotherapy in cancer patients. J. Immunol. Methods 174:297.
20. Spenlehauer, C., S. Saragosti, H. J. Fleury, A. Kirn, A. M. Aubertin, and C. Moog. 1998. Study of the V3 loop as a target epitope for antibodies involved in the neutralization of primary isolates versus T-cell-line-adapted strains of human immunodeficiency virus type 1. J. Virol. 72:9855.
21. Burrer, R., D. Salmon-Ceron, S. Richert, G. Pancino, G. Spiridon, S. Haessig, V. Roques, F. Barre-Sinoussi, A. M. Aubertin, and C. Moog. 2001. Immunoglobulin G (IgG) and IgA, but also nonantibody factors, account for in vitro neutralization of human immunodeficiency virus (HIV) type I primary isolates by serum and plasma of HIV-infected patients. J. Virol. 75:5421.
22. Dimmock, N. J. 1993. Neutralization of animal viruses. Curr. Top. Microbiol. Immunol. 183:1.
23. Lizeng, Q., P. Skott, S. Sourial, C. Nilsson, S. S. Andersson, M. Ehnlund, N. Taveira, and E. Bjorling. 2003. Serum immunoglobulin A (IgA)-mediated immunity in human immunodeficiency virus type 2 (HIV-2) infection. Virology 308:225.
24. Wu, L., W. A. Paxton, N. Kassam, N. Ruffing, J. B. Rottman, N. Sullivan, H. Choe, J. Sodroski, W. Newman, R. A. Koup, and C. R. Mackay. 1997. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185:1681.
25. Jiang, Y., and P. E. Jolly. 1999. Effect of β-chemokines on human immunodeficiency virus type 1 replication, binding, uncoating, and CCR5 receptor expression in human monocyte-derived macrophages. J. Hum. Virol. 2:123.
26. + T cells. Science 270:1811.
27. Burton, D. R., J. Pyati, R. Koduri, S. J. Sharp, G. B. Thornton, P. W. Parren, L. S. Sawyer, R. M. Hendry, N. Dunlop, P. L. Nara, et al. 1994. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266:1024.
28. D'Souza, M. P., D. Livnat, J. A. Bradac, and S. H. Bridges. 1997. Evaluation of monoclonal antibodies to human immunodeficiency virus type I primary isolates by neutralization assays: performance criteria for selecting candidate antibodies for clinical trials. AIDS Clinical Trials Group Antibody Selection Working Group. J. Infect. Dis. 175:1056.
29. Moulard, M., S. K. Phogat, Y. Shu, A. F. Labrijn, X. Xiao, J. M. Binley, M. Y. Zhang, I. A. Sidorov, C. C. Broder, J. Robinson, et al. 2002. Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes. Proc. Natl. Acad. Sci. USA 99:6913.
30. Zwick, M. B., A. F. Labrijn, M. Wang, C. Spenlehauer, E. O. Saphire, J. M. Binley, J. P. Moore, G. Stiegler, H. Katinger, D. R. Burton, and P. W. Parren. 2001. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J. Virol. 75:10892.
31. Zwick, M. B., P. W. Parren, E. O. Saphire, S. Church, M. Wang, J. K. Scott, P. E. Dawson, I. A. Wilson, and D. R. Burton. 2003. Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120. J. Virol. 77:5863.
32. Zwick, M. B., R. Kelleher, R. Jensen, A. F. Labrijn, M. Wang, G. V. Quinnan, Jr., P. W. Parren, and D. R. Burton. 2003. A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12. J. Virol. 77:6965.
33. Stamatatos, L., S. Zolla-Pazner, M. K. Gorny, and C. Cheng-Mayer. 1997. Binding of antibodies to virion-associated gp120 molecules of primary-like human immunodeficiency virus type 1 (HIV-1) isolates: effect on HIV-1 infection of macrophages and peripheral blood mononuclear cells. Virology 229:360.
34. Collman, R., B. Godfrey, J. Cutilli, A. Rhodes, N. F. Hassan, R. Sweet, S. D. Douglas, H. Friedman, N. Nathanson, and F. Gonzalez-Scarano. 1990. Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor. J. Virol. 64:4468.
35. Nyambi, P. N., H. A. Mbah, S. Burda, C. Williams, M. K. Gorny, A. Nadas, and S. Zolla-Pazner. 2000. Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M. J. Virol. 74:7096.
36. Daeron, M. 1997. Fc receptor biology. Annu. Rev. Immunol. 15:203.
37. Mabondzo, A., F. Boussin, H. Raoul, R. Le Naour, G. Gras, B. Vaslin, J. Bartholeyns, J. L. Romet-Lemonne, and D. Dormont. 1994. Antibody-dependent cellular cytotoxicity and neutralization of human immunodeficiency virus type 1 by high affinity cross-linking of gp41 to human macrophage Fc IgG receptor using bispecific antibody. J. Gen. Virol. 75:1451.
38. Posner, M. R., H. S. Elboim, T. Cannon, L. Cavacini, and T. Hideshima. 1992. Functional activity of an HIV-1 neutralizing IgG human monoclonal antibody: ADCC and complement-mediated lysis. AIDS Res. Hum. Retroviruses 8:553.
39. Sullivan, B. L., E. J. Knopoff, M. Saifuddin, D. M. Takefman, M. N. Saarloos, B. E. Sha, and G. T. Spear. 1996. Susceptibility of HIV-1 plasma virus to complement-mediated lysis: evidence for a role in clearance of virus in vivo. J. Immunol. 157:1791.
40. Trischmann, H., D. Davis, and P. J. Lachmann. 1995. Lymphocytotropic strains of HIV type 1 when complexed with enhancing antibodies can infect macrophages via FcγRIII, independently of CD4. AIDS Res. Hum. Retroviruses 11:343.
41. Perez-Bercoff, D., A. David, H. Sudry, F. Barre-Sinoussi, and G. Pancino. 2003. Fcγ receptor-mediated suppression of human immunodeficiency virus type 1 replication in primary human macrophages. J. Virol. 77:4081.
42. Marsh, C. B., R. P. Pomerantz, J. M. Parker, A. V. Winnard, E. L. Mazzaferri, Jr., N. Moldovan, T. W. Kelley, E. Beck, and M. D. Wewers. 1999. Regulation of monocyte survival in vitro by deposited IgG: role of macrophage colony-stimulating factor. J. Immunol. 162:6217.
43. Kelly, M. D., H. M Naif, S. L. Adams, A. L. Cunningham, and A. R. Lloyd. 1998. Dichotomous effects of β-chemokines on HIV replication in monocytes and monocyte-derived macrophages. J. Immunol. 160:3091.
44. Bender, B. S., B. L. Davidson, R. Kline, C. Brown, and T. C. Quinn. 1988. Role of the mononuclear phagocyte system in the immunopathogenesis of human immunodeficiency virus infection and the acquired immunodeficiency syndrome. Rev. Infect. Dis. 10:1142.
45. Kedzierska, K., P. Ellery, J. Mak, S. R. Lewin, S. M. Crowe, and A. Jaworowski. 2002. HIV-1 down-modulates γ signaling chain of FcγR in human macrophages: a possible mechanism for inhibition of phagocytosis. J. Immunol. 168:2895.
46. Smith-Franklin, B. A., B. F. Keele, J. G. Tew, S. Gartner, A. K. Szakal, J. D. Estes, T. C. Thacker, and G. F. Burton. 2002. Follicular dendritic cells and the persistence of HIV infectivity: the role of antibodies and Fcγ receptors. J. Immunol. 168:2408.
47. Mascola, J. R., M. G. Lewis, G. Stiegler, D. Harris, T. C. VanCott, D. Hayes, M. K. Louder, C. R. Brown, C. V. Sapan, S. S. Frankel, et al. 1999. Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J. Virol. 73:4009.
48. Binley, J. M., B. Clas, A. Gettie, M. Vesanen, D. C. Montefiori, L. Sawyer, J. Booth, M. Lewis, P. A. Marx, S. Bonhoeffer, and J. P. Moore. 2000. Passive infusion of immune serum into simian immunodeficiency virus-infected rhesus macaques undergoing a rapid disease course has minimal effect on plasma viremia. Virology 270:237.