Recombinant Ascaris 16-kilodalton protein-induced protection against Ascaris suum larval migration after intranasal vaccination in pigs

Journal of Infectious Diseases

Volumn 190, Issue 10, 2004, Pages 1812-1820

  Tsuji, Naotoshi ^a   Miyoshi, Takeharu ^a   Islam, M Khyrul ^a   Isobe, Takashi ^a   Yoshihara, Shinobu ^a   Arakawa, Takeshi ^b   Matsumoto, Yasunobu ^c   Yokomizo, Yuichi ^a  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASCARIS ANTIGEN; CHOLERA TOXIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 4; PARASITE ANTIGEN; RECOMBINANT AS16 PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCARIS; ASCARIS SUUM; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; MOLTING; NONHUMAN; PARASITE MIGRATION; PARASITE SURVIVAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SWINE; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; ASCARIASIS; ASCARIS SUUM; CELLS, CULTURED; CHOLERA TOXIN; DIGESTIVE SYSTEM; HELMINTH PROTEINS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN-10; INTERLEUKIN-4; LEUKOCYTES, MONONUCLEAR; LUNG; RECOMBINANT PROTEINS; SWINE; SWINE DISEASES; VACCINES, SYNTHETIC;

EID: 8444242460     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/425074     Document Type: Article

References (49)

1. Chan MS. The global burden of intestinal nematode infections: fifty years on. Parasitol Today 1997; 13:438-43.
2. Crompton DWT. Ascaris and ascariasis. Adv Parasitol 2001; 48:285-375.
3. Anderson TJ, Romero-Abal ME, Jaenike J. Genetic structure and epidemiology of Ascaris populations: patterns of host affiliation in Guatemala. Parasitology 1993; 107:319-34.
4. Inatomi Y, Murakami T, Tokunaga M, Ishiwata K, Nawa Y, Uchino M. Encephalopathy caused by visceral larva migrans due to Ascaris suum. J Neurol Sci 1999; 164:195-9.
5. Maruyama H, Nawa Y, Noda S, Mimori T, Choi WY. An outbreak of visceral larva migrans due to Ascaris suum in Kyushu, Japan. Lancet 1996; 347:1766-7.
6. Wossene A, Tsuji N, Kasuga-Aoki H, et al. Lung stage protein profile and antigenic relationship between Ascaris lumbricoides and Ascaris suum. J Parasitol 2002; 88:826-8.
7. Kurimoto H. Morphological, biochemical and immunological studies on the differences between Ascaris lumbricoides Linneaus, 1758 and Ascaris suum Goeze, 1782. Jpn J Parasitol 1974; 23:251-67.
8. Nadler SA. Biochemical and immunological systematics of some Ascaridoid nematodes: genetic divergence between congeners. J Parasitol 1987; 73:811-6.
9. Peng W, Anderson TJ, Zhou X, Kennedy MW. Genetic variation in sympatric Ascaris populations from humans and pigs in China. Parasitology 1998; 117:355-61.
10. Kelly G, Nayak DP. Acquired immunity to migrating larvae of Ascaris suum induced in pigs by repeated oral inoculation of infective eggs. J Parasitol 1964; 50:499-503.
11. Stankiewicz M, Jeska EL. Evaluation of pyrantel-tartrate abbreviated Ascaris suum infections for the development of resistance in young pigs against migrating larvae. Int J Parasitol 1990; 20:77-81.
12. Urban JF Jr, Tromba FG. Development of immune responsiveness to Ascaris suum antigens in pigs vaccinated with ultraviolet-attenuated eggs. Vet Immunol Immunopathol 1982; 3:399-409.
13. Urban JF Jr, Romanowski RD. Ascaris suum: protective immunity in pigs immunized with products from eggs and larvae. Exp Parasitol 1985; 60:245-54.
14. Khoury PB, Stromberg BE, Soulsby EJ. Immune mechanisms to Ascaris suum in inbred guinea-pigs. I. Passive transfer of immunity by cells or serum. Immunology 1977; 32:405-11.
15. Yamamoto M, McGhee JR, Hagiwara Y, Otake S, Kiyono H. Genetically manipulated bacterial toxin as a new generation mucosal adjuvant. Scand J Immunol 2001; 53:211-7.
16. Johansson EL, Wassen L, Holmgren J, Jertborn M, Rudin A. Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans. Infect Immun 2001; 69:7481-6.
17. Kozlowski PA, Williams SB, Lynch RM, et al. Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle. J Immunol 2002; 169:566-74.
18. Chen D, Colditz IG, Glenn GM, Tsonis CG. Effect of transcutaneous immunization with co-administered antigen and cholera toxin on systemic and mucosal antibody responses in sheep. Vet Immunol Immunopathol 2002; 86:177-82.
19. Foss DL, Murtaugh MP. Mucosal immunogenicity and adjuvanticity of cholera toxin in swine. Vaccine 1999; 17:788-801.
20. Yokomizo Y, Watanabe F, Imada Y, Inumaru S, Yanaka T, Tsuji T. Mucosal immunoadjuvant activity of the low toxic recombinant Escherichia coli heat-labile enterotoxin produced by Bacillus brevis for the bacterial subunit or component vaccine in pigs and cattle. Vet Immunol Immunopathol 2002; 87:291-300.
21. Gregory WF, Atmadja AK, Allen JE, Maizels RM. The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun 2000; 68:4174-9.
22. Tsuji N, Suzuki k, Kasuga-Aoki H, Isobe T, Arakawa T, Matsumoto Y. Mice intranasally immunized with a recombinant 16-kilodalton antigen from the roundworm Ascaris parasites are protected against larval migration of Ascaris suum. Infect Immun 2003; 71:5314-23.
23. Geenen PL, Bresciani J, Boes J, et al. The morphogenesis of Ascaris suum to the infective third-stage larvae within the egg. J Parasitol 1999; 85:616-22.
24. Slotved HC, Eriksen L, Murrell KD, Nansen P. Early Ascaris suum migration in mice as a model for pigs. J Parasitol 1998; 84:16-8.
25. Slotved HC, Roepstorff A, Barnes EH, Eriksen L, Nansen P. Comparison of two methods for recovering migrating Ascaris suum larvae from the liver and lungs of pigs. J Parasitol 1996; 82:612-5.
26. Islam MK, Miyoshi T, Kasuga-Aoki H, et al. Inorganic pyrophosphatase in the roundworm Ascaris, and its role in the development and molting process of the larval stage parasites. Eur J Biochem 2003; 270:2814-26.
27. Hill DE, Fetterer RH, Romanowski RD, Urban JF Jr. The effect of immunization of pigs with Ascaris suum cuticle components on the development of resistance to parenteral migration during a challenge infection. Vet Immunol Immunopathol 1994; 42:161-9.
28. Jungersen G, Eriksen L, Roepstorff A, et al. Experimental Ascaris suum infection in the pig: protective memory response after three immunizations and effect of intestinal adult worm population. Parasite Immunol 1999; 21:619-30.
29. Eriksson K, Holmgren J. Recent advances in mucosal vaccines and adjuvants. Curr Opin Immunol 2002; 14:666-72.
30. McGhee JR, Kiyono H. The mucosal immune system. In: Paul WE, ed. Fundamental immunology. 4th ed. Philadelphia: Lippincott-Raven, 1999:909-45.
31. Spangler BD. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 1992; 56:622-47.
32. van Ginkel FW, Nguyen HH, McGhee JR. Vaccines for mucosal immunity to combat emerging infectious diseases. Emerg Infect Dis 2000; 6:123-32.
33. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-73.
34. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17:138-46.
35. Crawley A, Raymond C, Wilkie BN. Control of immunoglobulin isotype production by porcine B-cells cultured with cytokines. Vet Immunol Immunopathol 2003; 91:141-54.
36. Blackwell NM, Else KJ. B cells and antibodies are required for resistance to the parasitic gastrointestinal nematode Trichuris muris. Infect Immun 2001; 69:3860-8.
37. Garside P, Kennedy MW, Wakelin D, Lawrence CE. Immunopathology of intestinal helminth infection. Parasite Immunol 2000; 22:605-12.
38. Allen JE, Maizels RM. Immunology of human helminth infection. Int Arch Allergy Immunol 1996; 109:3-10.
39. Maizels RM, Holland MJ, Falcone FH, Zang XX, Yazdanbakhsh M. Vaccination against helminth parasites-the ultimate challenge for vaccinologists? Immunol Rev 1999; 171:125-47.
40. Cooper PJ, Chico ME, Sandoval C, et al. Human infection with Ascaris lumbricoides is associated with a polarized cytokine response. J Infect Dis 2000; 182:1207-13.
41. Claerebout E, Vercruysse J. The immune response and the evaluation of acquired immunity against gastrointestinal nematodes in cattle. Parasitology 2000; 120(Suppl):S25-42.
42. Munn EA, Smith TS, Smith H, James FM, Smith FC, Andrews SJ. Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11. Parasite Immunol 1997; 19:243-8.
43. Dalton JP, McGonigle S, Rolph TP, Andrews SJ. Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and with hemoglobin. Infect Immun 1996; 64:5066-74.
44. Stear MJ, Strain S, Bishop SC. Mechanisms underlying resistance to nematode infection. Int J Parasitol 1999; 29:51-6.
45. Sun JB, Mielcarek N, Lakew M, et al. Intranasal administration of a Schistosoma mansoni glutathione S-transferase-cholera toxoid conjugate vaccine evokes antiparasitic and antipathological immunity in mice. J Immunol 1999; 163:1045-52.
46. Harnett W, Harnett MM. Phosphorylcholine: friend or foe of the immune system? Immunol Today 1999; 20:125-9.
47. Lightowlers MW, Rickard MD. Excretory-secretory products of helminth parasites: effects on host immune responses. Parasitology 1988; 96:S123-66.
48. Maizels RM, Blaxter ML, Selkirk ME. Forms and functions of nematode surfaces. Exp Parasitol 1993; 77:380-4.
49. Jeska EL, Stankiewicz M. Responses of NFR/N inbred mice to very low-dose infections with Ascaris suum. Int J Parasitol 1989; 19:85-9.