Activation of dendritic cells by liposomes prepared from phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette-Guérin and adjuvant activity in vivo

Infection and Immunity

Volumn 72, Issue 9, 2004, Pages 5235-5246

  Sprott, G Dennis ^a   Dicaire, Chantal J ^a   Gurnani, Komal ^a   Sad, Subash ^a   Krishnan, Lakshmi ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BCG VACCINE; CARDIOLIPIN; CHLOROFORM; DIPALMITOYLPHOSPHATIDYLINOSITOLDIMANNOSIDE; GLYCEROLIPID; GLYCOLIPID; INTERLEUKIN 12; INTERLEUKIN 6; LIPID; LIPOSOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MANNOSE; MANNOSIDE; OVALBUMIN; PALMITOYLPHOSPHATIDYLINOSITOLDIMANNOSIDE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOLDIMANNOSIDE; PHOSPHATIDYLINOSITOLMANNOSIDE; PHOSPHOLIPID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG ACTIVITY; ENCAPSULATION; HUMORAL IMMUNITY; IMMUNIZATION; IN VIVO STUDY; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGEN PRESENTATION; ANTIGENS, CD80; CATTLE; DENDRITIC CELLS; IMMUNIZATION; LIPOSOMES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM BOVIS; OVALBUMIN; PHOSPHATIDYLINOSITOLS; T-LYMPHOCYTES, CYTOTOXIC; UP-REGULATION;

EID: 4544288852     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.9.5235-5246.2004     Document Type: Article

References (32)

1. Barratt, G., J. P. Tenu, A. Yapo, and J. F. Petit. 1986. Preparation and characterisation of liposomes containing mannosylated phospholipids capable of targetting drugs to macrophages. Biochim. Biophys. Acta 862:153-164.
2. Besra, G. S., and P. J. Brennan. 1994. The glycolipids of mycobacteria, p. 203-232. In C. Fenselau (ed.), Mass spectrometry for the characterization of microorganisms. Oxford University Press, New York, N.Y.
3. Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Med. Sci. 37:911-917.
4. Brennan, P., and C. E. Ballou. 1967. Biosynthesis of mannophosphoinositides by Mycobacterium phlei. The family of dimannophosphoinositides. J. Biol. Chem. 242:3046-3056.
5. Campos, M. A., I. C. Almeida, O. Takeuchi, S. Akira, E. P. Valente, D. O. Procopio, L. R. Travassos. J. A. Smith, D. T. Golenbock, and R. T. Gazzinelli. 2001. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J. Immunol. 167:416-423.
6. Connor, J., M. B. Yatvin, and L. Huang. 1984. pH-sensitive liposomes: acid-induced liposome fusion. Proc. Natl. Acad. Sci. USA 81:1715-1718.
7. Dudani, R., Y. Chapdelaine, H. H. Faassen, D. K. Smith, H. Shen, L. Krishnan, and S. Sad. 2002. Multiple mechanisms compensate to enhance tumor-protective CD8(+) T cell response in the long-term despite poor CD8(+) T cell priming initially: comparison between an acute versus a chronic intracellular bacterium expressing a model antigen. J. Immunol. 168:5737-5745.
8. Freund, J. 1956. The mode of action of immunologic adjuvants. Bibl. Tuberc. 5:130-148.
9. Gilleron, M., C. Ronet, M. Mempel, B. Monsarrat, G. Gachelin, and G. Puzo. 2001. Acylation state of the phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette Guerin and ability to induce granuloma and recruit natural killer T cells. J. Biol. Chem. 276:34896-34904.
10. Kates, M. 1978. The phytanyl ether-linked polar lipids and isoprenoid neutral lipids of extremely halophilic bacteria. Prog. Chem. Fats Other Lipids 15:301-342.
11. Kates, M. 1986. Techniques of lipidology: isolation, analysis, and identification of lipids. Elsevier, New York, N.Y.
12. Koike, Y., Y. C. Yoo, M. Mitobe, T. Oka, K. Okuma, S. Tono-oka, and I. Azuma. 1998. Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine. Vaccine 16:1982-1989.
13. Krishnan, L., C. J. Dicaire, G. B. Patel, and G. D. Sprott. 2000. Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum. Infect. Immun. 68:54-63.
14. + T cell help. J. Immunol. 165:5177-5185.
15. Krishnan, L., S. Sad, G. B. Patel, and G. D. Sprott. 2001. The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo. J. Immunol. 166:1885-1893.
16. Krishnan, L., S. Sad, G. B. Patel, and G. D. Sprott. 2003. Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped soluble protein in the absence of interleukin 12 and protect against tumor challenge. Cancer Res. 63:2526-2534.
17. Leopold, K., and W. Fischer. 1993. Molecular analysis of the lipoglycans of Mycobacterium tuberculosis. Anal. Biochem. 208:57-64.
18. Lichtenberg, D., and Y. Barenholz. 1988. Liposomes: preparation, characterization, and preservation. Methods Biochem. Anal. 33:337-462.
19. Mosmann, T. R., and T. A. Fong. 1989. Specific assays for cytokine production by T cells. J. Immunol. Methods 116:151-158.
20. Nigou, J., M. Gilleron, B. Cahuzac, J. D. Bounery, M. Herold, M. Thurnher, and G. Puzo. 1997. The phosphatidyl-myo-inositol anchor of the lipoarabinomannans from Mycobacterium bovis bacillus Calmette Guerin. Heterogeneity, structure, and role in the regulation of cytokine secretion. J. Biol. Chem. 272:23094-23103.
21. Nigou, J., M. Gilleron, and G. Puzo. 1999. Lipoarabinomannans: characterization of the multiacylated forms of the phosphatidyl-myo-inositol anchor by NMR spectroscopy. Biochem. J. 337:453-460.
22. Ortalo-Magne, A., A. Lemassu, M. A. Laneelle, F. Bardou, G. Silve, P. Gounon, G. Marchal, and M. Daffe. 1996. Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species. J. Bacteriol. 178:456-461.
23. Pangborn, M. G, and J. A. McKinney. 1966. Purification of serologically active phosphoinositides Mycobacterium tuberculosis. J. Lipid Res. 7:627-633.
24. Retzinger, G. S., S. C. Meredith, K. Takayama, R. L. Hunter, and F. J. Kezdy. 1981. The role of surface in the biological activities of trehalose 6,6′-dimycolate. Surface properties and development of a model system. J. Biol. Chem. 256:8208-8216.
25. Sad, S., R. Marcotte, and T. R. Mosmann. 1995. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity 2:271-279.
26. Skinner, M. A., R. Prestidge, S. Yuan, T. J. Strabala, and P. L. Tan. 2001. The ability of heat-killed Mycobacterium vaccae to stimulate a cytotoxic T-cell response to an unrelated protein is associated with a 65 kilodalton heat-shock protein. Immunology 102:225-233.
27. Sprott, G. D., J. Brisson, C. J. Dicaire, A. K. Pelletier, L. A. Deschatelets, L. Krishnan, and G. B. Patel. 1999. A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities of their liposomes. Biochim. Biophys. Acta 1440:275-288.
28. Sprott, G. D., D. L. Tolson, and G. B. Patel. 1997. Archaeosomes as novel antigen delivery systems. FEMS Microbiol. Lett. 154:17-22.
29. Straubinger, R. M., N. Duzgunes, and D. Papahadjopoulos. 1985. pH-sensitive liposomes mediate cytoplasmic delivery of encapsulated macromolecules. FEES Lett. 179:148-154.
30. Tenu, J. P., D. Sekkai, A. Yapo, J. F. Petit, and G. Lemaire. 1995. Phosphatidylinositolmannoside-based liposomes induce NO synthase in primed mouse peritoneal macrophages. Biochem. Biophys. Res. Commun. 208:295-301.
31. Vijh, S., and E. G. Pamer. 1997. Immunodominant and subdominant CTL responses to Listeria monocytogenes infection. J. Immunol. 158:3366-3371.
32. Wang, L., R. A. Slayden, C. E. Barry III, and J. Liu. 2000. Cell wall structure of a mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids. J. Biol. Chem. 275:7224-7229.