Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT

Molecular Cell

Volumn 44, Issue 6, 2011, Pages 997-1004

  Yang, Jing ^a   Kulkarni, Kiran ^a   Manolaridis, Ioannis ^a   Zhang, Ziguo ^a   Dodd, Roger B ^a   Mas Droux, Corine ^a   Barford, David ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CARBOXYL GROUP; CYSTEINE; ISOPRENYLCYSTEINE CARBOXYL; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYTOSOL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; HYDROGEN BOND; HYDROPHILICITY; LIPOPHILICITY; METHANOSARCINA ACETIVORANS; NONHUMAN; ORTHOLOGY; PRENYLATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN METHYLATION; PROTEIN STRUCTURE;

CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; CYTOSOL; LIPID METABOLISM; METHANOSARCINA; METHYLATION; MODELS, MOLECULAR; MUTATION; PROTEIN METHYLTRANSFERASES; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLMETHIONINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84255161994     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.10.020     Document Type: Article

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